Putative DNA polymerase kappa

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Download

Quick info

Protein:

Gene product:

DNA polymerase kappa, putative

Species:

Leishmania braziliensis

UniProt:

A4HGJ5_LEIBR

TriTrypDb:

LbrM.28.1590 , LBRM2903_280022000

Length:

138

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HGJ5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HGJ5

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	2
GO:0003887	DNA-directed DNA polymerase activity	5	2
GO:0016740	transferase activity	2	2
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	2
GO:0016779	nucleotidyltransferase activity	4	2
GO:0034061	DNA polymerase activity	4	2
GO:0140097	catalytic activity, acting on DNA	3	2
GO:0140640	catalytic activity, acting on a nucleic acid	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	120	122	PF00675	0.850
CLV_NRD_NRD_1	14	16	PF00675	0.801
CLV_NRD_NRD_1	82	84	PF00675	0.719
CLV_PCSK_KEX2_1	14	16	PF00082	0.801
CLV_PCSK_KEX2_1	81	83	PF00082	0.739
CLV_PCSK_SKI1_1	91	95	PF00082	0.813
DEG_Nend_UBRbox_4	1	3	PF02207	0.729
DOC_CKS1_1	103	108	PF01111	0.834
DOC_USP7_MATH_1	8	12	PF00917	0.767
DOC_WW_Pin1_4	102	107	PF00397	0.831
DOC_WW_Pin1_4	109	114	PF00397	0.729
DOC_WW_Pin1_4	31	36	PF00397	0.732
LIG_14-3-3_CanoR_1	126	135	PF00244	0.845
LIG_14-3-3_CanoR_1	14	19	PF00244	0.800
LIG_Actin_WH2_2	21	39	PF00022	0.762
LIG_eIF4E_1	23	29	PF01652	0.790
LIG_FHA_1	49	55	PF00498	0.724
LIG_FHA_1	60	66	PF00498	0.521
LIG_FHA_2	103	109	PF00498	0.837
LIG_FHA_2	65	71	PF00498	0.723
LIG_LIR_Nem_3	46	52	PF02991	0.721
LIG_LYPXL_yS_3	49	52	PF13949	0.726
LIG_PTB_Apo_2	58	65	PF02174	0.700
LIG_SH2_CRK	21	25	PF00017	0.807
LIG_SH2_GRB2like	23	26	PF00017	0.800
LIG_SH2_NCK_1	30	34	PF00017	0.736
LIG_SH2_SRC	45	48	PF00017	0.702
LIG_SH2_SRC	5	8	PF00017	0.736
LIG_SH2_STAT5	23	26	PF00017	0.800
LIG_SH2_STAT5	30	33	PF00017	0.621
LIG_SH3_3	1	7	PF00018	0.721
LIG_SH3_3	100	106	PF00018	0.825
LIG_SH3_3	44	50	PF00018	0.708
MOD_CDC14_SPxK_1	34	37	PF00782	0.732
MOD_CDK_SPK_2	109	114	PF00069	0.851
MOD_CDK_SPxK_1	31	37	PF00069	0.732
MOD_CDK_SPxxK_3	102	109	PF00069	0.836
MOD_CK1_1	127	133	PF00069	0.843
MOD_CK1_1	13	19	PF00069	0.799
MOD_CK1_1	85	91	PF00069	0.770
MOD_CK2_1	102	108	PF00069	0.833
MOD_Cter_Amidation	119	122	PF01082	0.850
MOD_GlcNHglycan	118	121	PF01048	0.849
MOD_GlcNHglycan	16	19	PF01048	0.794
MOD_GlcNHglycan	31	34	PF01048	0.463
MOD_GSK3_1	10	17	PF00069	0.796
MOD_GSK3_1	109	116	PF00069	0.850
MOD_GSK3_1	120	127	PF00069	0.656
MOD_GSK3_1	55	62	PF00069	0.694
MOD_GSK3_1	82	89	PF00069	0.743
MOD_N-GLC_1	116	121	PF02516	0.851
MOD_N-GLC_1	133	138	PF02516	0.553
MOD_N-GLC_1	83	88	PF02516	0.733
MOD_NEK2_1	125	130	PF00069	0.848
MOD_NEK2_1	28	33	PF00069	0.749
MOD_NEK2_1	64	69	PF00069	0.719
MOD_PKA_1	14	20	PF00069	0.801
MOD_PKA_1	82	88	PF00069	0.735
MOD_PKA_2	113	119	PF00069	0.853
MOD_PKA_2	120	126	PF00069	0.726
MOD_PKA_2	13	19	PF00069	0.799
MOD_PKA_2	82	88	PF00069	0.735
MOD_PKB_1	81	89	PF00069	0.743
MOD_Plk_1	55	61	PF00069	0.688
MOD_Plk_2-3	55	61	PF00069	0.688
MOD_ProDKin_1	102	108	PF00069	0.833
MOD_ProDKin_1	109	115	PF00069	0.727
MOD_ProDKin_1	31	37	PF00069	0.732
TRG_ENDOCYTIC_2	21	24	PF00928	0.812
TRG_ENDOCYTIC_2	49	52	PF00928	0.726
TRG_ER_diArg_1	80	83	PF00400	0.724