PSP1 C-terminal domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HGI7_LEIBR

TriTrypDb:

LbrM.28.1500 , LBRM2903_350087300

Length:

241

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 18
NetGPI	no	yes: 0, no: 18

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HGI7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HGI7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	168	172	PF00656	0.418
CLV_C14_Caspase3-7	57	61	PF00656	0.544
CLV_PCSK_SKI1_1	155	159	PF00082	0.297
CLV_PCSK_SKI1_1	203	207	PF00082	0.272
DEG_Nend_Nbox_1	1	3	PF02207	0.577
DOC_MAPK_gen_1	20	28	PF00069	0.673
DOC_MAPK_gen_1	212	220	PF00069	0.311
DOC_MAPK_MEF2A_6	125	133	PF00069	0.434
DOC_MAPK_MEF2A_6	20	28	PF00069	0.564
DOC_PP1_RVXF_1	201	208	PF00149	0.233
DOC_PP1_RVXF_1	212	218	PF00149	0.243
DOC_PP1_SILK_1	151	156	PF00149	0.341
DOC_USP7_MATH_1	149	153	PF00917	0.548
LIG_14-3-3_CanoR_1	134	144	PF00244	0.441
LIG_14-3-3_CanoR_1	155	164	PF00244	0.259
LIG_FHA_1	145	151	PF00498	0.590
LIG_FHA_2	140	146	PF00498	0.534
LIG_FHA_2	156	162	PF00498	0.297
LIG_FHA_2	2	8	PF00498	0.680
LIG_FHA_2	211	217	PF00498	0.426
LIG_IBAR_NPY_1	44	46	PF08397	0.571
LIG_LIR_Apic_2	66	72	PF02991	0.440
LIG_LIR_Gen_1	216	225	PF02991	0.323
LIG_LIR_Nem_3	192	198	PF02991	0.418
LIG_LIR_Nem_3	216	220	PF02991	0.262
LIG_LIR_Nem_3	223	228	PF02991	0.257
LIG_MAD2	22	30	PF02301	0.413
LIG_SH2_CRK	69	73	PF00017	0.470
LIG_SH2_PTP2	118	121	PF00017	0.373
LIG_SH2_SRC	69	72	PF00017	0.418
LIG_SH2_STAT5	118	121	PF00017	0.385
LIG_SH2_STAT5	143	146	PF00017	0.540
LIG_SH3_3	12	18	PF00018	0.590
LIG_SH3_3	82	88	PF00018	0.600
LIG_TRAF2_1	63	66	PF00917	0.639
MOD_CK1_1	139	145	PF00069	0.570
MOD_CK2_1	139	145	PF00069	0.519
MOD_CK2_1	155	161	PF00069	0.264
MOD_GlcNHglycan	56	59	PF01048	0.657
MOD_GSK3_1	135	142	PF00069	0.538
MOD_N-GLC_1	135	140	PF02516	0.400
MOD_NEK2_1	1	6	PF00069	0.696
MOD_NEK2_1	107	112	PF00069	0.535
MOD_PIKK_1	136	142	PF00454	0.638
MOD_PIKK_1	155	161	PF00454	0.274
MOD_PKA_1	203	209	PF00069	0.271
MOD_Plk_4	107	113	PF00069	0.383
MOD_Plk_4	11	17	PF00069	0.410
MOD_Plk_4	139	145	PF00069	0.539
MOD_Plk_4	149	155	PF00069	0.297
MOD_Plk_4	203	209	PF00069	0.239
MOD_Plk_4	93	99	PF00069	0.544
MOD_SUMO_rev_2	163	172	PF00179	0.374
MOD_SUMO_rev_2	197	205	PF00179	0.279
TRG_ENDOCYTIC_2	118	121	PF00928	0.335
TRG_ER_diArg_1	212	215	PF00400	0.379

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8D9	Leptomonas seymouri	77%	100%
A0A0S4J404	Bodo saltans	38%	68%
A0A0S4JV55	Bodo saltans	38%	72%
A0A0S4KL40	Bodo saltans	57%	100%
A0A1X0NLP9	Trypanosomatidae	62%	100%
A0A1X0NWX9	Trypanosomatidae	43%	80%
A0A3Q8ILM8	Leishmania donovani	84%	100%
A0A3R7M5V2	Trypanosoma rangeli	61%	100%
A0A3S5ISC8	Trypanosoma rangeli	38%	80%
A4ICE2	Leishmania infantum	84%	100%
C9ZYF4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	94%
D0A3S8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	56%	100%
D0A7N8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	77%
E9AUD9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%
E9B726	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	86%
Q4Q051	Leishmania major	86%	99%
V5BB20	Trypanosoma cruzi	39%	80%