Neur_chan_memb domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved (fragment)

Species:

Leishmania braziliensis

UniProt:

A4HGF7_LEIBR

TriTrypDb:

LbrM.28.1200 , LBRM2903_280018000

Length:

159

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A4HGF7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HGF7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	68	70	PF00675	0.586
CLV_PCSK_KEX2_1	68	70	PF00082	0.586
DEG_Nend_Nbox_1	1	3	PF02207	0.849
DOC_CKS1_1	18	23	PF01111	0.846
DOC_CKS1_1	61	66	PF01111	0.789
DOC_CKS1_1	95	100	PF01111	0.549
DOC_MAPK_gen_1	72	81	PF00069	0.758
DOC_MAPK_MEF2A_6	141	150	PF00069	0.449
DOC_MAPK_MEF2A_6	74	83	PF00069	0.650
DOC_USP7_MATH_1	31	35	PF00917	0.842
DOC_USP7_MATH_1	45	49	PF00917	0.642
DOC_WW_Pin1_4	101	106	PF00397	0.501
DOC_WW_Pin1_4	17	22	PF00397	0.848
DOC_WW_Pin1_4	60	65	PF00397	0.788
DOC_WW_Pin1_4	94	99	PF00397	0.549
LIG_14-3-3_CanoR_1	103	111	PF00244	0.597
LIG_14-3-3_CanoR_1	17	21	PF00244	0.846
LIG_14-3-3_CanoR_1	27	36	PF00244	0.724
LIG_EH1_1	148	156	PF00400	0.549
LIG_eIF4E_1	128	134	PF01652	0.594
LIG_eIF4E_1	149	155	PF01652	0.549
LIG_FHA_1	104	110	PF00498	0.597
LIG_GBD_Chelix_1	146	154	PF00786	0.549
LIG_LIR_Gen_1	142	153	PF02991	0.449
LIG_LIR_Gen_1	57	65	PF02991	0.792
LIG_LIR_Gen_1	76	86	PF02991	0.412
LIG_LIR_Nem_3	142	148	PF02991	0.449
LIG_LIR_Nem_3	48	53	PF02991	0.810
LIG_LIR_Nem_3	57	61	PF02991	0.683
LIG_LIR_Nem_3	76	81	PF02991	0.412
LIG_Pex14_2	78	82	PF04695	0.549
LIG_SH2_CRK	102	106	PF00017	0.593
LIG_SH2_PTP2	149	152	PF00017	0.549
LIG_SH2_SRC	110	113	PF00017	0.603
LIG_SH2_STAT5	110	113	PF00017	0.603
LIG_SH2_STAT5	131	134	PF00017	0.595
LIG_SH2_STAT5	138	141	PF00017	0.495
LIG_SH2_STAT5	145	148	PF00017	0.305
LIG_SH2_STAT5	149	152	PF00017	0.234
LIG_SH2_STAT5	60	63	PF00017	0.783
LIG_SH3_2	64	69	PF14604	0.791
LIG_SH3_3	61	67	PF00018	0.788
LIG_SUMO_SIM_par_1	82	87	PF11976	0.549
MOD_CK1_1	104	110	PF00069	0.597
MOD_CK1_1	12	18	PF00069	0.849
MOD_GlcNHglycan	22	25	PF01048	0.649
MOD_GlcNHglycan	29	32	PF01048	0.559
MOD_GSK3_1	101	108	PF00069	0.378
MOD_GSK3_1	12	19	PF00069	0.847
MOD_GSK3_1	27	34	PF00069	0.662
MOD_GSK3_1	84	91	PF00069	0.549
MOD_N-GLC_1	136	141	PF02516	0.787
MOD_N-GLC_1	38	43	PF02516	0.632
MOD_NEK2_1	2	7	PF00069	0.837
MOD_NEK2_1	26	31	PF00069	0.858
MOD_NEK2_1	84	89	PF00069	0.549
MOD_NEK2_2	105	110	PF00069	0.599
MOD_PKA_2	16	22	PF00069	0.849
MOD_PKA_2	26	32	PF00069	0.729
MOD_Plk_1	136	142	PF00069	0.584
MOD_Plk_1	9	15	PF00069	0.844
MOD_Plk_4	105	111	PF00069	0.599
MOD_Plk_4	129	135	PF00069	0.592
MOD_Plk_4	84	90	PF00069	0.549
MOD_ProDKin_1	101	107	PF00069	0.502
MOD_ProDKin_1	17	23	PF00069	0.848
MOD_ProDKin_1	60	66	PF00069	0.788
MOD_ProDKin_1	94	100	PF00069	0.549
MOD_SUMO_for_1	119	122	PF00179	0.608
TRG_ENDOCYTIC_2	131	134	PF00928	0.595
TRG_ENDOCYTIC_2	145	148	PF00928	0.305
TRG_ENDOCYTIC_2	149	152	PF00928	0.234
TRG_ENDOCYTIC_2	50	53	PF00928	0.813
TRG_ER_diArg_1	67	69	PF00400	0.787