Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HGB9_LEIBR

TriTrypDb:

LbrM.28.0810

Length:

192

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HGB9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HGB9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	74	78	PF00656	0.502
CLV_MEL_PAP_1	147	153	PF00089	0.501
CLV_NRD_NRD_1	129	131	PF00675	0.542
CLV_NRD_NRD_1	174	176	PF00675	0.613
CLV_NRD_NRD_1	27	29	PF00675	0.529
CLV_PCSK_KEX2_1	128	130	PF00082	0.469
CLV_PCSK_KEX2_1	176	178	PF00082	0.509
CLV_PCSK_KEX2_1	27	29	PF00082	0.529
CLV_PCSK_KEX2_1	88	90	PF00082	0.732
CLV_PCSK_PC1ET2_1	176	178	PF00082	0.509
CLV_PCSK_PC1ET2_1	88	90	PF00082	0.732
CLV_PCSK_SKI1_1	130	134	PF00082	0.471
CLV_PCSK_SKI1_1	144	148	PF00082	0.566
DEG_APCC_DBOX_1	174	182	PF00400	0.583
DEG_APCC_KENBOX_2	106	110	PF00400	0.574
DEG_SPOP_SBC_1	167	171	PF00917	0.453
DOC_PP4_FxxP_1	90	93	PF00568	0.501
DOC_USP7_MATH_1	61	65	PF00917	0.641
DOC_USP7_MATH_1	73	77	PF00917	0.579
DOC_USP7_MATH_1	98	102	PF00917	0.571
DOC_WW_Pin1_4	160	165	PF00397	0.472
DOC_WW_Pin1_4	54	59	PF00397	0.648
DOC_WW_Pin1_4	89	94	PF00397	0.509
LIG_14-3-3_CanoR_1	150	157	PF00244	0.521
LIG_14-3-3_CanoR_1	185	189	PF00244	0.538
LIG_14-3-3_CanoR_1	33	42	PF00244	0.466
LIG_14-3-3_CanoR_1	89	93	PF00244	0.729
LIG_BIR_II_1	1	5	PF00653	0.642
LIG_BRCT_BRCA1_1	14	18	PF00533	0.514
LIG_BRCT_BRCA1_1	75	79	PF00533	0.561
LIG_FHA_1	151	157	PF00498	0.501
LIG_FHA_1	38	44	PF00498	0.539
LIG_FHA_2	136	142	PF00498	0.525
LIG_FHA_2	161	167	PF00498	0.480
LIG_FHA_2	18	24	PF00498	0.571
LIG_FHA_2	8	14	PF00498	0.646
LIG_Pex14_2	133	137	PF04695	0.509
LIG_SH2_STAP1	34	38	PF00017	0.454
LIG_SH2_STAT5	3	6	PF00017	0.497
LIG_SH2_STAT5	30	33	PF00017	0.605
LIG_SH2_STAT5	34	37	PF00017	0.658
LIG_SH3_3	110	116	PF00018	0.594
LIG_SH3_3	161	167	PF00018	0.466
LIG_SH3_3	41	47	PF00018	0.620
LIG_TRAF2_1	10	13	PF00917	0.582
MOD_CK1_1	135	141	PF00069	0.593
MOD_CK1_1	91	97	PF00069	0.536
MOD_CK2_1	135	141	PF00069	0.593
MOD_CK2_1	160	166	PF00069	0.564
MOD_CK2_1	7	13	PF00069	0.588
MOD_GlcNHglycan	80	84	PF01048	0.591
MOD_GlcNHglycan	93	96	PF01048	0.594
MOD_GSK3_1	166	173	PF00069	0.661
MOD_GSK3_1	33	40	PF00069	0.480
MOD_GSK3_1	4	11	PF00069	0.571
MOD_GSK3_1	56	63	PF00069	0.633
MOD_GSK3_1	94	101	PF00069	0.521
MOD_N-GLC_2	6	8	PF02516	0.555
MOD_NEK2_1	132	137	PF00069	0.479
MOD_NEK2_1	17	22	PF00069	0.561
MOD_NEK2_1	184	189	PF00069	0.426
MOD_NEK2_1	79	84	PF00069	0.577
MOD_PIKK_1	8	14	PF00454	0.646
MOD_PKA_1	88	94	PF00069	0.674
MOD_PKA_2	149	155	PF00069	0.543
MOD_PKA_2	184	190	PF00069	0.496
MOD_PKA_2	32	38	PF00069	0.477
MOD_PKA_2	88	94	PF00069	0.614
MOD_Plk_1	79	85	PF00069	0.714
MOD_Plk_4	132	138	PF00069	0.516
MOD_Plk_4	98	104	PF00069	0.681
MOD_ProDKin_1	160	166	PF00069	0.475
MOD_ProDKin_1	54	60	PF00069	0.649
MOD_ProDKin_1	89	95	PF00069	0.503
TRG_ER_diArg_1	128	130	PF00400	0.542
TRG_ER_diArg_1	174	177	PF00400	0.600
TRG_NES_CRM1_1	104	118	PF08389	0.585

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7T0	Leptomonas seymouri	41%	96%
A0A3S7X1A2	Leishmania donovani	70%	100%
E9ADJ8	Leishmania major	74%	100%
E9AHH7	Leishmania infantum	71%	100%
E9AZP0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	74%	100%