LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HGB6_LEIBR
TriTrypDb:
LbrM.28.0780 , LBRM2903_280013300 *
Length:
71

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HGB6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HGB6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 36 38 PF00675 0.610
CLV_NRD_NRD_1 41 43 PF00675 0.631
CLV_PCSK_KEX2_1 36 38 PF00082 0.620
CLV_PCSK_KEX2_1 41 43 PF00082 0.642
CLV_PCSK_PC7_1 37 43 PF00082 0.574
CLV_PCSK_SKI1_1 27 31 PF00082 0.428
DEG_Nend_UBRbox_1 1 4 PF02207 0.566
DOC_CYCLIN_RxL_1 23 34 PF00134 0.421
DOC_MAPK_MEF2A_6 62 71 PF00069 0.472
LIG_PCNA_yPIPBox_3 41 53 PF02747 0.360
LIG_PDZ_Class_2 66 71 PF00595 0.493
MOD_GSK3_1 63 70 PF00069 0.463
MOD_NEK2_1 63 68 PF00069 0.584
MOD_PIKK_1 36 42 PF00454 0.465
MOD_PKA_1 18 24 PF00069 0.451
MOD_PKA_1 36 42 PF00069 0.465
MOD_PKA_2 36 42 PF00069 0.465
MOD_SUMO_for_1 17 20 PF00179 0.468
TRG_DiLeu_BaEn_2 10 16 PF01217 0.497
TRG_DiLeu_BaEn_4 11 17 PF01217 0.490
TRG_ER_diArg_1 35 37 PF00400 0.617
TRG_ER_diArg_1 41 43 PF00400 0.625
TRG_Pf-PMV_PEXEL_1 23 28 PF00026 0.450
TRG_Pf-PMV_PEXEL_1 41 46 PF00026 0.364

Homologs

Protein Taxonomy Sequence identity Coverage
E9AZN7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 96% 100%
Q4Q8J4 Leishmania major 90% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS