BTB domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

btb/poz domain containing protein, putative

Species:

Leishmania braziliensis

UniProt:

A4HGB0_LEIBR

TriTrypDb:

LbrM.28.0720 , LBRM2903_280012700

Length:

190

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HGB0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HGB0

Function

Biological processes
Term	Name	Level	Count
GO:0009987	cellular process	1	2
GO:0016043	cellular component organization	3	2
GO:0022607	cellular component assembly	4	2
GO:0043933	protein-containing complex organization	4	2
GO:0051259	protein complex oligomerization	6	2
GO:0051260	protein homooligomerization	7	2
GO:0065003	protein-containing complex assembly	5	2
GO:0071840	cellular component organization or biogenesis	2	2

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	31	35	PF00656	0.790
CLV_NRD_NRD_1	150	152	PF00675	0.804
CLV_PCSK_KEX2_1	150	152	PF00082	0.804
CLV_PCSK_KEX2_1	7	9	PF00082	0.839
CLV_PCSK_PC1ET2_1	7	9	PF00082	0.839
CLV_PCSK_SKI1_1	119	123	PF00082	0.549
CLV_PCSK_SKI1_1	27	31	PF00082	0.807
DEG_SCF_FBW7_2	143	148	PF00400	0.775
DOC_MAPK_gen_1	147	155	PF00069	0.799
DOC_MAPK_gen_1	7	17	PF00069	0.840
DOC_MAPK_MEF2A_6	170	177	PF00069	0.766
DOC_PP1_RVXF_1	149	156	PF00149	0.802
DOC_USP7_MATH_1	146	150	PF00917	0.783
DOC_USP7_MATH_1	157	161	PF00917	0.582
DOC_WW_Pin1_4	141	146	PF00397	0.775
DOC_WW_Pin1_4	153	158	PF00397	0.588
DOC_WW_Pin1_4	35	40	PF00397	0.767
DOC_WW_Pin1_4	60	65	PF00397	0.549
LIG_FHA_2	36	42	PF00498	0.740
LIG_LIR_Gen_1	72	82	PF02991	0.549
LIG_LIR_Gen_1	93	102	PF02991	0.549
LIG_LIR_LC3C_4	112	116	PF02991	0.549
LIG_LIR_Nem_3	149	155	PF02991	0.804
LIG_LIR_Nem_3	72	78	PF02991	0.549
LIG_LIR_Nem_3	93	98	PF02991	0.549
LIG_SH2_CRK	105	109	PF00017	0.549
LIG_SH2_STAT5	101	104	PF00017	0.549
LIG_SH3_3	161	167	PF00018	0.767
LIG_SUMO_SIM_anti_2	112	118	PF11976	0.549
LIG_SUMO_SIM_anti_2	160	165	PF11976	0.764
LIG_SUMO_SIM_anti_2	41	47	PF11976	0.549
MOD_CDK_SPxK_1	141	147	PF00069	0.776
MOD_CDK_SPxxK_3	35	42	PF00069	0.746
MOD_CK1_1	62	68	PF00069	0.549
MOD_Cter_Amidation	5	8	PF01082	0.847
MOD_GlcNHglycan	11	15	PF01048	0.847
MOD_GSK3_1	153	160	PF00069	0.791
MOD_GSK3_1	48	55	PF00069	0.549
MOD_GSK3_1	56	63	PF00069	0.410
MOD_NEK2_1	56	61	PF00069	0.549
MOD_PKA_2	146	152	PF00069	0.790
MOD_PKA_2	22	28	PF00069	0.806
MOD_PKB_1	8	16	PF00069	0.841
MOD_Plk_4	159	165	PF00069	0.766
MOD_Plk_4	171	177	PF00069	0.554
MOD_Plk_4	62	68	PF00069	0.549
MOD_ProDKin_1	141	147	PF00069	0.776
MOD_ProDKin_1	153	159	PF00069	0.585
MOD_ProDKin_1	35	41	PF00069	0.753
MOD_ProDKin_1	60	66	PF00069	0.549
MOD_SUMO_for_1	129	132	PF00179	0.662
TRG_ER_diArg_1	150	152	PF00400	0.804

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A6H6X4	BOVIN	32%	73%
B1WC97	RAT	31%	66%
Q6DG99	DANRE	43%	80%
Q6DK85	XENTR	38%	68%
Q8WVF5	HUMAN	32%	73%
Q96MP8	HUMAN	37%	66%
Q9D7X1	MOUSE	32%	73%
Q9SE95	ARATH	35%	64%