Serine/threonine-protein phosphatase

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

serine/threonine protein phosphatase catalytic subunit, putative

Species:

Leishmania braziliensis

UniProt:

A4HGA9_LEIBR

TriTrypDb:

LbrM.28.0710 , LBRM2903_280012600

Length:

301

Annotations

LeishMANIAdb annotations

A large collection of various protein phosphatases. Very highly expanded in kinetoplastids.

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 9
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 21

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0000164	protein phosphatase type 1 complex	5	5
GO:0005634	nucleus	5	1
GO:0005737	cytoplasm	2	1
GO:0005815	microtubule organizing center	2	1
GO:0008287	protein serine/threonine phosphatase complex	4	5
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032991	protein-containing complex	1	5
GO:0036064	ciliary basal body	3	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0110165	cellular anatomical entity	1	1
GO:1902494	catalytic complex	2	5
GO:1903293	phosphatase complex	3	5

Expansion

Sequence features

A4HGA9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HGA9

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	11
GO:0004721	phosphoprotein phosphatase activity	3	11
GO:0004722	protein serine/threonine phosphatase activity	4	11
GO:0005488	binding	1	11
GO:0016787	hydrolase activity	2	11
GO:0016788	hydrolase activity, acting on ester bonds	3	11
GO:0016791	phosphatase activity	5	11
GO:0017018	myosin phosphatase activity	5	11
GO:0042578	phosphoric ester hydrolase activity	4	11
GO:0043167	ion binding	2	11
GO:0043169	cation binding	3	11
GO:0046872	metal ion binding	4	11
GO:0140096	catalytic activity, acting on a protein	2	11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	136	138	PF00675	0.285
CLV_NRD_NRD_1	254	256	PF00675	0.501
CLV_PCSK_KEX2_1	135	137	PF00082	0.285
CLV_PCSK_KEX2_1	254	256	PF00082	0.385
CLV_PCSK_PC1ET2_1	135	137	PF00082	0.285
CLV_PCSK_PC1ET2_1	254	256	PF00082	0.385
CLV_PCSK_SKI1_1	14	18	PF00082	0.347
CLV_PCSK_SKI1_1	144	148	PF00082	0.285
CLV_PCSK_SKI1_1	181	185	PF00082	0.419
CLV_PCSK_SKI1_1	256	260	PF00082	0.434
CLV_PCSK_SKI1_1	30	34	PF00082	0.206
DOC_CYCLIN_yCln2_LP_2	49	55	PF00134	0.474
DOC_MAPK_gen_1	135	142	PF00069	0.285
DOC_MAPK_gen_1	14	24	PF00069	0.452
DOC_MAPK_gen_1	254	260	PF00069	0.342
DOC_PP1_RVXF_1	103	109	PF00149	0.285
DOC_PP1_RVXF_1	213	220	PF00149	0.363
DOC_PP2B_LxvP_1	49	52	PF13499	0.452
DOC_PP4_FxxP_1	261	264	PF00568	0.299
DOC_USP7_MATH_2	203	209	PF00917	0.285
DOC_USP7_UBL2_3	228	232	PF12436	0.303
DOC_USP7_UBL2_3	291	295	PF12436	0.414
DOC_WW_Pin1_4	168	173	PF00397	0.285
LIG_14-3-3_CanoR_1	215	220	PF00244	0.285
LIG_Actin_WH2_2	276	293	PF00022	0.347
LIG_AP2alpha_1	146	150	PF02296	0.285
LIG_BIR_II_1	1	5	PF00653	0.292
LIG_BRCT_BRCA1_1	217	221	PF00533	0.285
LIG_Clathr_ClatBox_1	46	50	PF01394	0.452
LIG_DLG_GKlike_1	215	223	PF00625	0.285
LIG_eIF4E_1	64	70	PF01652	0.285
LIG_FHA_1	190	196	PF00498	0.328
LIG_FHA_1	34	40	PF00498	0.547
LIG_FHA_1	95	101	PF00498	0.285
LIG_LIR_Apic_2	197	203	PF02991	0.285
LIG_LIR_Apic_2	259	264	PF02991	0.321
LIG_LIR_Gen_1	147	158	PF02991	0.285
LIG_LIR_Gen_1	246	257	PF02991	0.398
LIG_LIR_Gen_1	286	294	PF02991	0.367
LIG_LIR_Gen_1	78	88	PF02991	0.285
LIG_LIR_Nem_3	110	115	PF02991	0.285
LIG_LIR_Nem_3	147	153	PF02991	0.285
LIG_LIR_Nem_3	246	252	PF02991	0.395
LIG_LIR_Nem_3	286	290	PF02991	0.339
LIG_LIR_Nem_3	78	84	PF02991	0.285
LIG_PCNA_PIPBox_1	223	232	PF02747	0.285
LIG_PCNA_yPIPBox_3	223	232	PF02747	0.285
LIG_Pex14_2	104	108	PF04695	0.285
LIG_Pex14_2	146	150	PF04695	0.285
LIG_PTB_Apo_2	69	76	PF02174	0.285
LIG_REV1ctd_RIR_1	110	120	PF16727	0.285
LIG_REV1ctd_RIR_1	249	260	PF16727	0.326
LIG_SH2_CRK	64	68	PF00017	0.285
LIG_SH2_STAT5	266	269	PF00017	0.379
LIG_SH2_STAT5	81	84	PF00017	0.324
LIG_SH2_STAT5	87	90	PF00017	0.354
LIG_SH2_STAT6	248	252	PF00017	0.326
LIG_SH3_3	103	109	PF00018	0.285
LIG_SH3_3	291	297	PF00018	0.457
LIG_SH3_4	17	24	PF00018	0.452
LIG_SH3_4	291	298	PF00018	0.447
LIG_SUMO_SIM_par_1	256	262	PF11976	0.334
LIG_SUMO_SIM_par_1	45	50	PF11976	0.452
LIG_UBA3_1	46	54	PF00899	0.452
LIG_WRC_WIRS_1	284	289	PF05994	0.352
MOD_CK1_1	2	8	PF00069	0.419
MOD_CK2_1	198	204	PF00069	0.287
MOD_CK2_1	2	8	PF00069	0.412
MOD_GlcNHglycan	207	210	PF01048	0.289
MOD_GlcNHglycan	261	264	PF01048	0.336
MOD_GlcNHglycan	271	275	PF01048	0.370
MOD_N-GLC_2	265	267	PF02516	0.342
MOD_NEK2_1	146	151	PF00069	0.285
MOD_NEK2_1	270	275	PF00069	0.345
MOD_NEK2_1	283	288	PF00069	0.351
MOD_PIKK_1	39	45	PF00454	0.507
MOD_PKA_1	181	187	PF00069	0.419
MOD_Plk_2-3	173	179	PF00069	0.285
MOD_Plk_4	2	8	PF00069	0.419
MOD_ProDKin_1	168	174	PF00069	0.285
MOD_SUMO_rev_2	26	32	PF00179	0.467
TRG_DiLeu_BaEn_1	96	101	PF01217	0.285
TRG_DiLeu_BaLyEn_6	42	47	PF01217	0.547
TRG_ENDOCYTIC_2	128	131	PF00928	0.285
TRG_ENDOCYTIC_2	249	252	PF00928	0.337
TRG_ENDOCYTIC_2	63	66	PF00928	0.285
TRG_ENDOCYTIC_2	81	84	PF00928	0.285
TRG_ER_diArg_1	136	138	PF00400	0.285
TRG_ER_diArg_1	34	37	PF00400	0.452
TRG_ER_diLys_1	296	301	PF00400	0.512
TRG_NES_CRM1_1	96	110	PF08389	0.285
TRG_NLS_MonoCore_2	294	299	PF00514	0.489
TRG_NLS_MonoExtN_4	292	299	PF00514	0.462

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7S7	Leptomonas seymouri	98%	100%
A0A0N1HSR2	Leptomonas seymouri	43%	81%
A0A0N1I0V3	Leptomonas seymouri	58%	77%
A0A0N1IBK9	Leptomonas seymouri	42%	98%
A0A0N1ILH2	Leptomonas seymouri	31%	71%
A0A0N1P9X9	Leptomonas seymouri	40%	98%
A0A0N1PAV9	Leptomonas seymouri	63%	83%
A0A0N1PCC5	Leptomonas seymouri	38%	97%
A0A0N1PDK9	Leptomonas seymouri	42%	95%
A0A0S4IIW0	Bodo saltans	33%	76%
A0A0S4ILF8	Bodo saltans	45%	99%
A0A0S4J1J1	Bodo saltans	38%	78%
A0A0S4JDD1	Bodo saltans	39%	67%
A0A0S4JJ52	Bodo saltans	64%	79%
A0A0S4JJ96	Bodo saltans	59%	96%
A0A0S4JJH3	Bodo saltans	58%	96%
A0A0S4KGD7	Bodo saltans	44%	100%
A0A0S4KKU2	Bodo saltans	42%	98%
A0A0S4KLF4	Bodo saltans	22%	73%
A0A0S4KM73	Bodo saltans	48%	76%
A0A1X0NK88	Trypanosomatidae	63%	87%
A0A1X0NMS7	Trypanosomatidae	24%	73%
A0A1X0NNN6	Trypanosomatidae	43%	90%
A0A1X0NS37	Trypanosomatidae	41%	100%
A0A1X0NS65	Trypanosomatidae	43%	99%
A0A1X0NUA6	Trypanosomatidae	41%	75%
A0A1X0NYR5	Trypanosomatidae	90%	99%
A0A1X0P6J3	Trypanosomatidae	39%	79%
A0A1X0P7H9	Trypanosomatidae	38%	67%
A0A1X0P7Q5	Trypanosomatidae	32%	78%
A0A1X0P982	Trypanosomatidae	57%	91%
A0A1X0P9R6	Trypanosomatidae	31%	66%
A0A1X0PA67	Trypanosomatidae	59%	100%
A0A1X0PAK9	Trypanosomatidae	59%	100%
A0A1X0PBJ2	Trypanosomatidae	36%	98%
A0A3Q8I8M6	Leishmania donovani	35%	70%
A0A3Q8IFB2	Leishmania donovani	57%	100%
A0A3Q8IH18	Leishmania donovani	45%	98%
A0A3Q8IHY7	Leishmania donovani	64%	100%
A0A3R7KQR6	Trypanosoma rangeli	43%	89%
A0A3R7M399	Trypanosoma rangeli	33%	69%
A0A3R7MBA3	Trypanosoma rangeli	37%	67%
A0A3R7MFZ7	Trypanosoma rangeli	55%	91%
A0A3R7MM48	Trypanosoma rangeli	41%	75%
A0A3R7N275	Trypanosoma rangeli	88%	99%
A0A3R7NP99	Trypanosoma rangeli	36%	98%
A0A3S5H6K2	Leishmania donovani	23%	71%
A0A3S5H6T9	Leishmania donovani	43%	80%
A0A3S5H7Q6	Leishmania donovani	64%	82%
A0A3S7WZ39	Leishmania donovani	42%	95%
A0A3S7X190	Leishmania donovani	99%	100%
A0A3S7X1Y0	Leishmania donovani	41%	98%
A0A3S7X7I6	Leishmania donovani	58%	100%
A0A3S7X7J8	Leishmania donovani	57%	100%
A0A3S7X7K2	Leishmania donovani	60%	99%
A0A3S7X8K6	Leishmania donovani	37%	97%
A0A3S7XAY3	Leishmania donovani	32%	74%
A0A422N8P1	Trypanosoma rangeli	58%	100%
A0A422N9D5	Trypanosoma rangeli	32%	76%
A0A422NKG0	Trypanosoma rangeli	40%	98%
A0A422NPG1	Trypanosoma rangeli	65%	86%
A0A422NYN7	Trypanosoma rangeli	42%	99%
A0A422P483	Trypanosoma rangeli	39%	71%
A0C1E4	Paramecium tetraurelia	43%	99%
A0CCD2	Paramecium tetraurelia	42%	98%
A0CNL9	Paramecium tetraurelia	49%	96%
A0DJ90	Paramecium tetraurelia	42%	99%
A2X2G3	Oryza sativa subsp. indica	43%	98%
A2XN40	Oryza sativa subsp. indica	44%	98%
A2YEB4	Oryza sativa subsp. indica	43%	98%
A3C4N5	Oryza sativa subsp. japonica	43%	96%
A4H7Z3	Leishmania braziliensis	43%	100%
A4HAI7	Leishmania braziliensis	58%	100%
A4HAI8	Leishmania braziliensis	61%	100%
A4HAI9	Leishmania braziliensis	57%	100%
A4HAJ8	Leishmania braziliensis	56%	100%
A4HBE2	Leishmania braziliensis	39%	100%
A4HE75	Leishmania braziliensis	41%	100%
A4HGX0	Leishmania braziliensis	41%	100%
A4HJQ1	Leishmania braziliensis	61%	100%
A4HKU9	Leishmania braziliensis	45%	98%
A4HP65	Leishmania braziliensis	32%	75%
A4HV49	Leishmania infantum	23%	71%
A4HVT0	Leishmania infantum	35%	70%
A4HWC1	Leishmania infantum	43%	80%
A4I1H6	Leishmania infantum	42%	95%
A4I3E3	Leishmania infantum	99%	100%
A4I400	Leishmania infantum	41%	98%
A4I768	Leishmania infantum	64%	82%
A4I8C8	Leishmania infantum	45%	98%
A4I9P2	Leishmania infantum	57%	100%
A4IAJ0	Leishmania infantum	37%	97%
A4IDH0	Leishmania infantum	32%	74%
A6H772	Bos taurus	44%	98%
A8WGP3	Danio rerio	44%	97%
A8XE00	Caenorhabditis briggsae	46%	90%
A9JRC7	Danio rerio	44%	98%
C9ZJZ6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	93%
C9ZM48	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	71%
C9ZMF3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	60%	87%
C9ZN02	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	56%	92%
C9ZN04	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	55%	100%
C9ZN06	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	57%	100%
C9ZWN3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	61%	87%
C9ZX13	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	70%
D0A358	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	77%
D0A805	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	87%	99%
D0A970	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	98%
D0AAU4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	99%
E9AHS8	Leishmania infantum	60%	100%
E9AHS9	Leishmania infantum	60%	99%
E9AHT0	Leishmania infantum	57%	100%
E9AHT1	Leishmania infantum	58%	100%
E9ANT1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	21%	71%
E9APH5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	70%
E9AQ21	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	80%
E9ASX3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	74%
E9AXL1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	95%
E9AZN0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
E9B090	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	98%
E9B262	Leishmania mexicana (strain MHOM/GT/2001/U1103)	63%	82%
E9B387	Leishmania mexicana (strain MHOM/GT/2001/U1103)	45%	98%
E9B4P8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	58%	100%
E9B4P9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	60%	97%
E9B4Q0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	58%	100%
E9B4Q1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	57%	100%
E9B4Q6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	57%	100%
E9B5L4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	97%
G5EGK8	Caenorhabditis elegans	45%	95%
O00743	Homo sapiens	44%	99%
O02658	Caenorhabditis elegans	52%	99%
O04856	Nicotiana tabacum	69%	95%
O04857	Nicotiana tabacum	70%	97%
O04858	Nicotiana tabacum	69%	99%
O04860	Nicotiana tabacum	44%	96%
O04951	Arabidopsis thaliana	43%	98%
O15757	Dictyostelium discoideum	73%	94%
O74789	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	86%
O76932	Drosophila melanogaster	43%	98%
O82733	Arabidopsis thaliana	68%	91%
O82734	Arabidopsis thaliana	65%	93%
P0C5D7	Oryza sativa subsp. indica	43%	96%
P11084	Oryctolagus cuniculus	43%	98%
P11493	Sus scrofa	47%	100%
P11611	Oryctolagus cuniculus	46%	97%
P11612	Drosophila melanogaster	59%	96%
P12982	Drosophila melanogaster	75%	100%
P13681	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	73%	92%
P20604	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	42%	97%
P20654	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	73%	93%
P22198	Zea mays	70%	95%
P23594	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	46%	82%
P23595	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	47%	80%
P23635	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	43%	97%
P23636	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	43%	93%
P23696	Drosophila melanogaster	45%	97%
P23733	Trypanosoma brucei brucei	60%	87%
P23734	Trypanosoma brucei brucei	61%	87%
P23777	Brassica napus	67%	100%
P23778	Brassica napus	44%	97%
P23880	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	70%	93%
P30366	Arabidopsis thaliana	70%	95%
P32345	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	41%	98%
P32598	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	73%	96%
P32838	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	40%	82%
P34350	Caenorhabditis elegans	31%	80%
P36614	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	41%	99%
P36873	Homo sapiens	76%	93%
P36874	Xenopus laevis	76%	93%
P48458	Caenorhabditis elegans	45%	83%
P48459	Caenorhabditis elegans	44%	66%
P48460	Caenorhabditis elegans	39%	66%
P48461	Drosophila melanogaster	74%	92%
P48462	Drosophila melanogaster	74%	91%
P48463	Gallus gallus	46%	97%
P48480	Acetabularia peniculus	74%	94%
P48481	Acetabularia peniculus	73%	94%
P48482	Arabidopsis thaliana	72%	96%
P48483	Arabidopsis thaliana	68%	93%
P48484	Arabidopsis thaliana	71%	94%
P48485	Arabidopsis thaliana	69%	96%
P48486	Arabidopsis thaliana	67%	93%
P48487	Brassica oleracea	69%	95%
P48488	Medicago sativa subsp. varia	70%	94%
P48489	Oryza sativa subsp. japonica	74%	93%
P48490	Phaseolus vulgaris	66%	96%
P48528	Arabidopsis thaliana	43%	99%
P48529	Arabidopsis thaliana	42%	99%
P48577	Acetabularia peniculus	45%	98%
P48578	Arabidopsis thaliana	44%	96%
P48579	Helianthus annuus	45%	99%
P48580	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	46%	92%
P48726	Paramecium tetraurelia	49%	96%
P48727	Caenorhabditis elegans	75%	90%
P49576	Paramecium tetraurelia	43%	99%
P60510	Homo sapiens	44%	98%
P61287	Bos taurus	76%	93%
P61292	Sus scrofa	75%	92%
P62136	Homo sapiens	74%	91%
P62137	Mus musculus	73%	91%
P62138	Rattus norvegicus	74%	91%
P62139	Oryctolagus cuniculus	74%	91%
P62140	Homo sapiens	75%	92%
P62141	Mus musculus	75%	92%
P62142	Rattus norvegicus	75%	92%
P62143	Oryctolagus cuniculus	75%	92%
P62207	Gallus gallus	75%	92%
P62714	Homo sapiens	46%	97%
P62715	Mus musculus	46%	97%
P62716	Rattus norvegicus	46%	97%
P63087	Mus musculus	76%	93%
P63088	Rattus norvegicus	76%	93%
P63330	Mus musculus	46%	97%
P63331	Rattus norvegicus	46%	97%
P67774	Bos taurus	46%	97%
P67775	Homo sapiens	46%	97%
P67776	Sus scrofa	46%	97%
P67777	Oryctolagus cuniculus	46%	97%
P91420	Caenorhabditis elegans	52%	99%
P97470	Mus musculus	44%	98%
Q05547	Drosophila melanogaster	73%	100%
Q06009	Medicago sativa	44%	96%
Q07098	Arabidopsis thaliana	44%	98%
Q07099	Arabidopsis thaliana	44%	98%
Q07100	Arabidopsis thaliana	44%	96%
Q09496	Caenorhabditis elegans	41%	91%
Q0DBD3	Oryza sativa subsp. japonica	43%	98%
Q0E2S4	Oryza sativa subsp. japonica	43%	98%
Q0P594	Bos taurus	46%	97%
Q10298	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	42%	98%
Q10BT5	Oryza sativa subsp. japonica	44%	98%
Q27497	Caenorhabditis elegans	73%	91%
Q27884	Drosophila melanogaster	43%	99%
Q3SWW9	Bos taurus	75%	92%
Q3T0E7	Bos taurus	74%	91%
Q4Q1M5	Leishmania major	32%	100%
Q4Q2C2	Leishmania major	37%	100%
Q4Q3C0	Leishmania major	57%	100%
Q4Q3C5	Leishmania major	58%	100%
Q4Q3C6	Leishmania major	58%	100%
Q4Q3C7	Leishmania major	61%	100%
Q4Q3C8	Leishmania major	59%	100%
Q4Q4W8	Leishmania major	43%	100%
Q4Q5Z8	Leishmania major	63%	100%
Q4Q7Z5	Leishmania major	41%	100%
Q4Q8K1	Leishmania major	99%	100%
Q4Q9W1	Leishmania major	42%	100%
Q4QFG0	Leishmania major	44%	100%
Q4QG03	Leishmania major	35%	70%
Q4QGT8	Leishmania major	21%	100%
Q4WM22	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	40%	78%
Q54RD6	Dictyostelium discoideum	44%	96%
Q59KY8	Candida albicans (strain SC5314 / ATCC MYA-2876)	41%	96%
Q5A6B6	Candida albicans (strain SC5314 / ATCC MYA-2876)	42%	72%
Q5BJ92	Rattus norvegicus	43%	98%
Q5I085	Xenopus tropicalis	75%	92%
Q5R6K8	Pongo abelii	44%	98%
Q5R740	Pongo abelii	75%	92%
Q61JR3	Caenorhabditis briggsae	73%	91%
Q627N3	Caenorhabditis briggsae	75%	90%
Q64620	Rattus norvegicus	44%	99%
Q6BFF6	Paramecium tetraurelia	48%	96%
Q6CNT6	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	40%	98%
Q6FM81	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	40%	97%
Q6GQL2	Xenopus laevis	75%	92%
Q6IP91	Xenopus laevis	44%	98%
Q6NVU2	Xenopus tropicalis	76%	93%
Q6P861	Xenopus tropicalis	44%	98%
Q74ZR2	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	39%	97%
Q7SZ10	Xenopus laevis	76%	93%
Q8LSN3	Pisum sativum	40%	99%
Q8MJ46	Canis lupus familiaris	75%	93%
Q8MJ47	Canis lupus familiaris	75%	92%
Q8WMS6	Canis lupus familiaris	73%	91%
Q8X178	Blumeria hordei	45%	92%
Q9CQR6	Mus musculus	44%	99%
Q9FN02	Arabidopsis thaliana	31%	73%
Q9HFQ2	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	45%	91%
Q9LHE7	Arabidopsis thaliana	40%	99%
Q9M9W3	Arabidopsis thaliana	66%	95%
Q9SX52	Arabidopsis thaliana	40%	99%
Q9U9A3	Dictyostelium discoideum	43%	99%
Q9UW86	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	73%	98%
Q9XGH7	Nicotiana tabacum	43%	96%
Q9XTT8	Caenorhabditis elegans	47%	94%
Q9XW79	Caenorhabditis elegans	46%	90%
Q9XZE5	Dictyostelium discoideum	45%	98%
Q9Y0B7	Dictyostelium discoideum	43%	99%
Q9ZSE4	Hevea brasiliensis	43%	98%
V5AUW3	Trypanosoma cruzi	54%	91%
V5B3V2	Trypanosoma cruzi	40%	79%
V5B5K9	Trypanosoma cruzi	41%	90%
V5B8G5	Trypanosoma cruzi	43%	89%
V5BBR3	Trypanosoma cruzi	33%	77%
V5BGM0	Trypanosoma cruzi	41%	76%
V5BKU4	Trypanosoma cruzi	89%	99%
V5BQD7	Trypanosoma cruzi	34%	69%
V5D2G9	Trypanosoma cruzi	66%	86%
V5DAX7	Trypanosoma cruzi	62%	100%
V5DCW3	Trypanosoma cruzi	40%	98%
V5DIG8	Trypanosoma cruzi	36%	69%
V5DMS5	Trypanosoma cruzi	37%	98%