| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 11 |
| NetGPI | no | yes: 0, no: 11 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005643 | nuclear pore | 3 | 11 |
| GO:0030117 | membrane coat | 3 | 12 |
| GO:0030120 | vesicle coat | 4 | 12 |
| GO:0030127 | COPII vesicle coat | 5 | 12 |
| GO:0032991 | protein-containing complex | 1 | 12 |
| GO:0098796 | membrane protein complex | 2 | 12 |
| GO:0140513 | nuclear protein-containing complex | 2 | 12 |
| GO:0005794 | Golgi apparatus | 5 | 1 |
| GO:0031080 | nuclear pore outer ring | 3 | 1 |
| GO:0043226 | organelle | 2 | 2 |
| GO:0043227 | membrane-bounded organelle | 3 | 1 |
| GO:0043229 | intracellular organelle | 3 | 2 |
| GO:0043231 | intracellular membrane-bounded organelle | 4 | 1 |
| GO:0110165 | cellular anatomical entity | 1 | 2 |
| GO:0005840 | ribosome | 5 | 1 |
| GO:0043228 | non-membrane-bounded organelle | 3 | 1 |
| GO:0043232 | intracellular non-membrane-bounded organelle | 4 | 1 |
| GO:1990904 | ribonucleoprotein complex | 2 | 1 |
Related structures:
AlphaFold database: A4HGA5
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006810 | transport | 3 | 12 |
| GO:0006900 | vesicle budding from membrane | 5 | 12 |
| GO:0006996 | organelle organization | 4 | 12 |
| GO:0008104 | protein localization | 4 | 12 |
| GO:0009966 | regulation of signal transduction | 4 | 12 |
| GO:0009967 | positive regulation of signal transduction | 5 | 12 |
| GO:0009987 | cellular process | 1 | 12 |
| GO:0010646 | regulation of cell communication | 4 | 12 |
| GO:0010647 | positive regulation of cell communication | 5 | 12 |
| GO:0015031 | protein transport | 4 | 12 |
| GO:0015931 | nucleobase-containing compound transport | 5 | 12 |
| GO:0016043 | cellular component organization | 3 | 12 |
| GO:0016050 | vesicle organization | 5 | 12 |
| GO:0023051 | regulation of signaling | 3 | 12 |
| GO:0023056 | positive regulation of signaling | 4 | 12 |
| GO:0032006 | regulation of TOR signaling | 6 | 12 |
| GO:0032008 | positive regulation of TOR signaling | 7 | 12 |
| GO:0033036 | macromolecule localization | 2 | 12 |
| GO:0045184 | establishment of protein localization | 3 | 12 |
| GO:0048518 | positive regulation of biological process | 3 | 12 |
| GO:0048522 | positive regulation of cellular process | 4 | 12 |
| GO:0048583 | regulation of response to stimulus | 3 | 12 |
| GO:0048584 | positive regulation of response to stimulus | 4 | 12 |
| GO:0050657 | nucleic acid transport | 6 | 12 |
| GO:0050658 | RNA transport | 4 | 12 |
| GO:0050789 | regulation of biological process | 2 | 12 |
| GO:0050794 | regulation of cellular process | 3 | 12 |
| GO:0051028 | mRNA transport | 5 | 12 |
| GO:0051179 | localization | 1 | 12 |
| GO:0051234 | establishment of localization | 2 | 12 |
| GO:0051236 | establishment of RNA localization | 3 | 12 |
| GO:0051641 | cellular localization | 2 | 12 |
| GO:0061024 | membrane organization | 4 | 12 |
| GO:0065007 | biological regulation | 1 | 12 |
| GO:0070727 | cellular macromolecule localization | 3 | 12 |
| GO:0071702 | organic substance transport | 4 | 12 |
| GO:0071705 | nitrogen compound transport | 4 | 12 |
| GO:0071840 | cellular component organization or biogenesis | 2 | 12 |
| GO:0090114 | COPII-coated vesicle budding | 6 | 12 |
| GO:1902531 | regulation of intracellular signal transduction | 5 | 12 |
| GO:1902533 | positive regulation of intracellular signal transduction | 6 | 12 |
| GO:1903432 | regulation of TORC1 signaling | 7 | 12 |
| GO:1904263 | positive regulation of TORC1 signaling | 8 | 12 |
| GO:0006606 | protein import into nucleus | 5 | 1 |
| GO:0006886 | intracellular protein transport | 4 | 1 |
| GO:0006913 | nucleocytoplasmic transport | 5 | 1 |
| GO:0033365 | protein localization to organelle | 5 | 1 |
| GO:0034504 | protein localization to nucleus | 6 | 1 |
| GO:0046907 | intracellular transport | 3 | 1 |
| GO:0051169 | nuclear transport | 4 | 1 |
| GO:0051170 | import into nucleus | 6 | 1 |
| GO:0051649 | establishment of localization in cell | 3 | 1 |
| GO:0072594 | establishment of protein localization to organelle | 4 | 1 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005198 | structural molecule activity | 1 | 12 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_C14_Caspase3-7 | 329 | 333 | PF00656 | 0.467 |
| CLV_NRD_NRD_1 | 114 | 116 | PF00675 | 0.455 |
| CLV_PCSK_SKI1_1 | 211 | 215 | PF00082 | 0.288 |
| CLV_PCSK_SKI1_1 | 219 | 223 | PF00082 | 0.292 |
| DOC_CKS1_1 | 122 | 127 | PF01111 | 0.297 |
| DOC_CKS1_1 | 255 | 260 | PF01111 | 0.522 |
| DOC_CYCLIN_yCln2_LP_2 | 269 | 275 | PF00134 | 0.413 |
| DOC_CYCLIN_yCln2_LP_2 | 302 | 305 | PF00134 | 0.449 |
| DOC_PP1_RVXF_1 | 259 | 266 | PF00149 | 0.317 |
| DOC_PP1_RVXF_1 | 314 | 320 | PF00149 | 0.330 |
| DOC_PP2B_LxvP_1 | 187 | 190 | PF13499 | 0.465 |
| DOC_PP2B_LxvP_1 | 269 | 272 | PF13499 | 0.478 |
| DOC_PP2B_LxvP_1 | 302 | 305 | PF13499 | 0.521 |
| DOC_PP4_FxxP_1 | 180 | 183 | PF00568 | 0.458 |
| DOC_PP4_FxxP_1 | 207 | 210 | PF00568 | 0.273 |
| DOC_USP7_MATH_1 | 27 | 31 | PF00917 | 0.459 |
| DOC_USP7_MATH_1 | 277 | 281 | PF00917 | 0.301 |
| DOC_WW_Pin1_4 | 121 | 126 | PF00397 | 0.413 |
| DOC_WW_Pin1_4 | 254 | 259 | PF00397 | 0.423 |
| DOC_WW_Pin1_4 | 306 | 311 | PF00397 | 0.595 |
| LIG_14-3-3_CanoR_1 | 115 | 121 | PF00244 | 0.350 |
| LIG_14-3-3_CanoR_1 | 211 | 220 | PF00244 | 0.387 |
| LIG_14-3-3_CanoR_1 | 348 | 356 | PF00244 | 0.541 |
| LIG_BIR_II_1 | 1 | 5 | PF00653 | 0.538 |
| LIG_BIR_III_4 | 20 | 24 | PF00653 | 0.414 |
| LIG_BRCT_BRCA1_1 | 173 | 177 | PF00533 | 0.254 |
| LIG_deltaCOP1_diTrp_1 | 157 | 165 | PF00928 | 0.367 |
| LIG_EVH1_2 | 203 | 207 | PF00568 | 0.374 |
| LIG_FHA_1 | 117 | 123 | PF00498 | 0.344 |
| LIG_FHA_1 | 157 | 163 | PF00498 | 0.449 |
| LIG_FHA_1 | 307 | 313 | PF00498 | 0.453 |
| LIG_FHA_1 | 32 | 38 | PF00498 | 0.440 |
| LIG_FHA_1 | 322 | 328 | PF00498 | 0.285 |
| LIG_FHA_1 | 6 | 12 | PF00498 | 0.297 |
| LIG_FHA_1 | 87 | 93 | PF00498 | 0.416 |
| LIG_FHA_2 | 2 | 8 | PF00498 | 0.485 |
| LIG_FHA_2 | 92 | 98 | PF00498 | 0.429 |
| LIG_Integrin_isoDGR_2 | 22 | 24 | PF01839 | 0.308 |
| LIG_LIR_Gen_1 | 241 | 252 | PF02991 | 0.481 |
| LIG_LIR_Gen_1 | 318 | 327 | PF02991 | 0.318 |
| LIG_LIR_Nem_3 | 111 | 117 | PF02991 | 0.385 |
| LIG_LIR_Nem_3 | 135 | 139 | PF02991 | 0.458 |
| LIG_LIR_Nem_3 | 174 | 180 | PF02991 | 0.444 |
| LIG_LIR_Nem_3 | 257 | 263 | PF02991 | 0.307 |
| LIG_LIR_Nem_3 | 318 | 322 | PF02991 | 0.327 |
| LIG_LIR_Nem_3 | 324 | 328 | PF02991 | 0.295 |
| LIG_LIR_Nem_3 | 58 | 63 | PF02991 | 0.407 |
| LIG_MAD2 | 348 | 356 | PF02301 | 0.541 |
| LIG_Pex14_1 | 224 | 228 | PF04695 | 0.473 |
| LIG_Pex14_2 | 177 | 181 | PF04695 | 0.388 |
| LIG_Pex14_2 | 220 | 224 | PF04695 | 0.360 |
| LIG_SH2_CRK | 114 | 118 | PF00017 | 0.415 |
| LIG_SH2_CRK | 136 | 140 | PF00017 | 0.427 |
| LIG_SH2_NCK_1 | 120 | 124 | PF00017 | 0.454 |
| LIG_SH2_NCK_1 | 38 | 42 | PF00017 | 0.414 |
| LIG_SH2_SRC | 330 | 333 | PF00017 | 0.474 |
| LIG_SH2_STAP1 | 118 | 122 | PF00017 | 0.313 |
| LIG_SH2_STAP1 | 88 | 92 | PF00017 | 0.360 |
| LIG_SH2_STAT5 | 118 | 121 | PF00017 | 0.337 |
| LIG_SH2_STAT5 | 275 | 278 | PF00017 | 0.278 |
| LIG_SH2_STAT5 | 88 | 91 | PF00017 | 0.453 |
| LIG_SH3_2 | 206 | 211 | PF14604 | 0.397 |
| LIG_SH3_3 | 176 | 182 | PF00018 | 0.332 |
| LIG_SH3_3 | 200 | 206 | PF00018 | 0.516 |
| LIG_SH3_CIN85_PxpxPR_1 | 206 | 211 | PF14604 | 0.378 |
| LIG_TRAF2_1 | 232 | 235 | PF00917 | 0.674 |
| LIG_TRAF2_1 | 69 | 72 | PF00917 | 0.478 |
| LIG_WRC_WIRS_1 | 162 | 167 | PF05994 | 0.489 |
| LIG_WRC_WIRS_1 | 322 | 327 | PF05994 | 0.307 |
| LIG_WW_3 | 208 | 212 | PF00397 | 0.351 |
| MOD_CDK_SPxxK_3 | 254 | 261 | PF00069 | 0.465 |
| MOD_CK1_1 | 164 | 170 | PF00069 | 0.419 |
| MOD_CK1_1 | 31 | 37 | PF00069 | 0.445 |
| MOD_CK1_1 | 40 | 46 | PF00069 | 0.406 |
| MOD_CK2_1 | 229 | 235 | PF00069 | 0.621 |
| MOD_CK2_1 | 348 | 354 | PF00069 | 0.535 |
| MOD_CK2_1 | 66 | 72 | PF00069 | 0.534 |
| MOD_CK2_1 | 91 | 97 | PF00069 | 0.336 |
| MOD_GlcNHglycan | 231 | 234 | PF01048 | 0.465 |
| MOD_GlcNHglycan | 235 | 239 | PF01048 | 0.468 |
| MOD_GlcNHglycan | 68 | 71 | PF01048 | 0.373 |
| MOD_GSK3_1 | 1 | 8 | PF00069 | 0.471 |
| MOD_GSK3_1 | 239 | 246 | PF00069 | 0.583 |
| MOD_GSK3_1 | 27 | 34 | PF00069 | 0.499 |
| MOD_GSK3_1 | 317 | 324 | PF00069 | 0.323 |
| MOD_N-GLC_1 | 312 | 317 | PF02516 | 0.538 |
| MOD_NEK2_1 | 1 | 6 | PF00069 | 0.576 |
| MOD_NEK2_1 | 317 | 322 | PF00069 | 0.327 |
| MOD_NEK2_1 | 326 | 331 | PF00069 | 0.284 |
| MOD_PIKK_1 | 46 | 52 | PF00454 | 0.616 |
| MOD_Plk_1 | 261 | 267 | PF00069 | 0.230 |
| MOD_Plk_1 | 46 | 52 | PF00069 | 0.687 |
| MOD_Plk_2-3 | 161 | 167 | PF00069 | 0.481 |
| MOD_Plk_4 | 1 | 7 | PF00069 | 0.494 |
| MOD_Plk_4 | 239 | 245 | PF00069 | 0.521 |
| MOD_Plk_4 | 321 | 327 | PF00069 | 0.317 |
| MOD_ProDKin_1 | 121 | 127 | PF00069 | 0.414 |
| MOD_ProDKin_1 | 254 | 260 | PF00069 | 0.411 |
| MOD_ProDKin_1 | 306 | 312 | PF00069 | 0.587 |
| TRG_DiLeu_BaLyEn_6 | 298 | 303 | PF01217 | 0.508 |
| TRG_ENDOCYTIC_2 | 114 | 117 | PF00928 | 0.460 |
| TRG_ENDOCYTIC_2 | 136 | 139 | PF00928 | 0.331 |
| TRG_ENDOCYTIC_2 | 38 | 41 | PF00928 | 0.398 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N1PEP1 | Leptomonas seymouri | 79% | 100% |
| A0A0S4JEG3 | Bodo saltans | 36% | 100% |
| A0A1X0NYI1 | Trypanosomatidae | 47% | 100% |
| A0A3Q8IDS6 | Leishmania donovani | 90% | 100% |
| A0A422P1N5 | Trypanosoma rangeli | 46% | 100% |
| A1CGS0 | Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) | 29% | 100% |
| A2QHM1 | Aspergillus niger (strain CBS 513.88 / FGSC A1513) | 29% | 100% |
| A3LNW3 | Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) | 28% | 100% |
| A4I3D9 | Leishmania infantum | 90% | 100% |
| A4REK3 | Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) | 29% | 100% |
| A5DHD9 | Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) | 27% | 100% |
| A5DXE2 | Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) | 29% | 100% |
| D0A808 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 42% | 100% |
| E9AZM6 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 91% | 100% |
| G0SA60 | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | 29% | 100% |
| O64740 | Arabidopsis thaliana | 32% | 100% |
| O94319 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 29% | 100% |
| P0CS50 | Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) | 29% | 100% |
| P0CS51 | Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) | 29% | 100% |
| P53024 | Komagataella phaffii (strain GS115 / ATCC 20864) | 26% | 100% |
| P55735 | Homo sapiens | 29% | 100% |
| Q04491 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 28% | 100% |
| Q0CHM0 | Aspergillus terreus (strain NIH 2624 / FGSC A1156) | 28% | 100% |
| Q0UNA9 | Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) | 30% | 100% |
| Q1DZQ0 | Coccidioides immitis (strain RS) | 29% | 100% |
| Q2GSM6 | Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) | 27% | 100% |
| Q2UG43 | Aspergillus oryzae (strain ATCC 42149 / RIB 40) | 28% | 100% |
| Q3ZCC9 | Bos taurus | 29% | 100% |
| Q4PCB8 | Ustilago maydis (strain 521 / FGSC 9021) | 30% | 98% |
| Q4Q8K5 | Leishmania major | 90% | 100% |
| Q4WNK7 | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) | 29% | 100% |
| Q54DS8 | Dictyostelium discoideum | 27% | 100% |
| Q5AEF2 | Candida albicans (strain SC5314 / ATCC MYA-2876) | 27% | 100% |
| Q5B563 | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) | 29% | 100% |
| Q5XFW8 | Rattus norvegicus | 28% | 100% |
| Q6BIR1 | Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) | 28% | 100% |
| Q6BZX5 | Yarrowia lipolytica (strain CLIB 122 / E 150) | 29% | 100% |
| Q6CSZ5 | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) | 28% | 100% |
| Q6FNV4 | Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) | 29% | 100% |
| Q6FQU6 | Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) | 25% | 100% |
| Q75BS2 | Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) | 26% | 100% |
| Q7RZF5 | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) | 27% | 100% |
| Q9D1M0 | Mus musculus | 28% | 100% |
| Q9N4A7 | Caenorhabditis elegans | 25% | 100% |
| Q9SRI1 | Arabidopsis thaliana | 31% | 100% |
| Q9V3J4 | Drosophila melanogaster | 29% | 100% |
| V5B0S9 | Trypanosoma cruzi | 47% | 100% |