Putative ribonuclease II-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DIS3-like exonuclease, putative

Species:

Leishmania braziliensis

UniProt:

A4HG84_LEIBR

TriTrypDb:

LbrM.28.0460 , LBRM2903_280010000

Length:

929

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0000178	exosome (RNase complex)	4	1
GO:0000932	P-body	5	1
GO:0005737	cytoplasm	2	1
GO:0032991	protein-containing complex	1	1
GO:0035770	ribonucleoprotein granule	3	1
GO:0036464	cytoplasmic ribonucleoprotein granule	4	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0099080	supramolecular complex	2	1
GO:0110165	cellular anatomical entity	1	1
GO:1902494	catalytic complex	2	1
GO:1905354	exoribonuclease complex	3	1

Expansion

Sequence features

A4HG84

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HG84

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006401	RNA catabolic process	5	1
GO:0006402	mRNA catabolic process	6	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009056	catabolic process	2	1
GO:0009057	macromolecule catabolic process	4	1
GO:0009892	negative regulation of metabolic process	4	1
GO:0009987	cellular process	1	1
GO:0010468	regulation of gene expression	5	1
GO:0010605	negative regulation of macromolecule metabolic process	5	1
GO:0010629	negative regulation of gene expression	6	1
GO:0016070	RNA metabolic process	5	1
GO:0016071	mRNA metabolic process	6	1
GO:0019222	regulation of metabolic process	3	1
GO:0019439	aromatic compound catabolic process	4	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0034655	nucleobase-containing compound catabolic process	4	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044248	cellular catabolic process	3	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0044265	obsolete cellular macromolecule catabolic process	4	1
GO:0044270	cellular nitrogen compound catabolic process	4	1
GO:0046483	heterocycle metabolic process	3	1
GO:0046700	heterocycle catabolic process	4	1
GO:0048519	negative regulation of biological process	3	1
GO:0050789	regulation of biological process	2	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0065007	biological regulation	1	1
GO:0071704	organic substance metabolic process	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1
GO:1901361	organic cyclic compound catabolic process	4	1
GO:1901575	organic substance catabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	11
GO:0003723	RNA binding	4	11
GO:0003824	catalytic activity	1	11
GO:0004518	nuclease activity	4	11
GO:0004540	RNA nuclease activity	4	11
GO:0005488	binding	1	11
GO:0016787	hydrolase activity	2	11
GO:0016788	hydrolase activity, acting on ester bonds	3	11
GO:0097159	organic cyclic compound binding	2	11
GO:0140098	catalytic activity, acting on RNA	3	11
GO:0140640	catalytic activity, acting on a nucleic acid	2	11
GO:1901363	heterocyclic compound binding	2	11
GO:0000175	3'-5'-RNA exonuclease activity	7	1
GO:0004527	exonuclease activity	5	3
GO:0004532	RNA exonuclease activity	5	1
GO:0008408	3'-5' exonuclease activity	6	1
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6	1
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	6	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	111	115	PF00656	0.513
CLV_C14_Caspase3-7	490	494	PF00656	0.565
CLV_C14_Caspase3-7	819	823	PF00656	0.480
CLV_C14_Caspase3-7	91	95	PF00656	0.397
CLV_NRD_NRD_1	306	308	PF00675	0.215
CLV_NRD_NRD_1	334	336	PF00675	0.321
CLV_NRD_NRD_1	365	367	PF00675	0.330
CLV_NRD_NRD_1	557	559	PF00675	0.268
CLV_NRD_NRD_1	564	566	PF00675	0.246
CLV_NRD_NRD_1	649	651	PF00675	0.215
CLV_NRD_NRD_1	687	689	PF00675	0.413
CLV_NRD_NRD_1	829	831	PF00675	0.695
CLV_PCSK_KEX2_1	156	158	PF00082	0.543
CLV_PCSK_KEX2_1	306	308	PF00082	0.218
CLV_PCSK_KEX2_1	365	367	PF00082	0.334
CLV_PCSK_KEX2_1	557	559	PF00082	0.276
CLV_PCSK_KEX2_1	649	651	PF00082	0.215
CLV_PCSK_KEX2_1	687	689	PF00082	0.636
CLV_PCSK_KEX2_1	752	754	PF00082	0.429
CLV_PCSK_PC1ET2_1	156	158	PF00082	0.543
CLV_PCSK_PC1ET2_1	752	754	PF00082	0.429
CLV_PCSK_SKI1_1	291	295	PF00082	0.528
CLV_PCSK_SKI1_1	356	360	PF00082	0.269
CLV_PCSK_SKI1_1	397	401	PF00082	0.215
CLV_PCSK_SKI1_1	477	481	PF00082	0.241
CLV_PCSK_SKI1_1	571	575	PF00082	0.283
CLV_PCSK_SKI1_1	658	662	PF00082	0.208
CLV_PCSK_SKI1_1	708	712	PF00082	0.472
CLV_PCSK_SKI1_1	752	756	PF00082	0.428
DEG_APCC_DBOX_1	657	665	PF00400	0.353
DOC_CDC14_PxL_1	677	685	PF14671	0.354
DOC_CYCLIN_RxL_1	655	665	PF00134	0.353
DOC_CYCLIN_RxL_1	705	715	PF00134	0.385
DOC_CYCLIN_yCln2_LP_2	59	65	PF00134	0.403
DOC_CYCLIN_yCln2_LP_2	905	908	PF00134	0.248
DOC_MAPK_gen_1	18	27	PF00069	0.377
DOC_MAPK_gen_1	44	54	PF00069	0.505
DOC_MAPK_gen_1	649	656	PF00069	0.428
DOC_MAPK_gen_1	895	905	PF00069	0.470
DOC_MAPK_MEF2A_6	168	175	PF00069	0.423
DOC_MAPK_MEF2A_6	658	666	PF00069	0.471
DOC_MAPK_MEF2A_6	895	903	PF00069	0.436
DOC_PP1_RVXF_1	500	506	PF00149	0.435
DOC_PP1_RVXF_1	543	550	PF00149	0.444
DOC_PP2B_LxvP_1	121	124	PF13499	0.609
DOC_PP2B_LxvP_1	675	678	PF13499	0.399
DOC_PP2B_LxvP_1	905	908	PF13499	0.343
DOC_PP4_FxxP_1	293	296	PF00568	0.370
DOC_PP4_FxxP_1	352	355	PF00568	0.471
DOC_PP4_FxxP_1	644	647	PF00568	0.415
DOC_USP7_MATH_1	107	111	PF00917	0.547
DOC_USP7_MATH_1	136	140	PF00917	0.467
DOC_USP7_MATH_1	3	7	PF00917	0.655
DOC_USP7_MATH_1	347	351	PF00917	0.415
DOC_USP7_MATH_1	573	577	PF00917	0.474
DOC_USP7_MATH_1	63	67	PF00917	0.518
DOC_USP7_MATH_1	816	820	PF00917	0.607
DOC_USP7_MATH_1	851	855	PF00917	0.705
DOC_USP7_MATH_1	862	866	PF00917	0.311
DOC_USP7_UBL2_3	473	477	PF12436	0.425
DOC_USP7_UBL2_3	481	485	PF12436	0.413
DOC_USP7_UBL2_3	831	835	PF12436	0.661
DOC_WW_Pin1_4	511	516	PF00397	0.555
DOC_WW_Pin1_4	643	648	PF00397	0.448
LIG_14-3-3_CanoR_1	34	43	PF00244	0.301
LIG_14-3-3_CanoR_1	365	373	PF00244	0.436
LIG_14-3-3_CanoR_1	383	391	PF00244	0.435
LIG_14-3-3_CanoR_1	898	902	PF00244	0.519
LIG_Actin_WH2_2	297	312	PF00022	0.488
LIG_Actin_WH2_2	479	494	PF00022	0.496
LIG_APCC_ABBA_1	711	716	PF00400	0.292
LIG_APCC_ABBA_1	880	885	PF00400	0.434
LIG_BIR_II_1	1	5	PF00653	0.470
LIG_BIR_III_2	812	816	PF00653	0.474
LIG_BRCT_BRCA1_1	400	404	PF00533	0.430
LIG_Clathr_ClatBox_1	403	407	PF01394	0.471
LIG_Clathr_ClatBox_1	661	665	PF01394	0.387
LIG_EH1_1	604	612	PF00400	0.509
LIG_eIF4E_1	605	611	PF01652	0.425
LIG_EVH1_2	515	519	PF00568	0.509
LIG_FHA_1	125	131	PF00498	0.518
LIG_FHA_1	22	28	PF00498	0.508
LIG_FHA_1	260	266	PF00498	0.293
LIG_FHA_1	35	41	PF00498	0.386
LIG_FHA_1	368	374	PF00498	0.473
LIG_FHA_1	643	649	PF00498	0.468
LIG_FHA_1	695	701	PF00498	0.438
LIG_FHA_1	705	711	PF00498	0.349
LIG_FHA_1	765	771	PF00498	0.449
LIG_FHA_1	856	862	PF00498	0.462
LIG_FHA_1	882	888	PF00498	0.352
LIG_FHA_1	921	927	PF00498	0.547
LIG_FHA_2	109	115	PF00498	0.567
LIG_FHA_2	320	326	PF00498	0.416
LIG_FHA_2	355	361	PF00498	0.509
LIG_FHA_2	604	610	PF00498	0.500
LIG_FHA_2	624	630	PF00498	0.323
LIG_FHA_2	86	92	PF00498	0.410
LIG_FHA_2	870	876	PF00498	0.460
LIG_IRF3_LxIS_1	459	464	PF10401	0.357
LIG_LIR_Apic_2	148	153	PF02991	0.473
LIG_LIR_Apic_2	292	296	PF02991	0.386
LIG_LIR_Apic_2	350	355	PF02991	0.419
LIG_LIR_Apic_2	642	647	PF02991	0.415
LIG_LIR_Gen_1	385	393	PF02991	0.416
LIG_LIR_Gen_1	532	542	PF02991	0.415
LIG_LIR_Gen_1	77	86	PF02991	0.386
LIG_LIR_Gen_1	878	888	PF02991	0.221
LIG_LIR_Nem_3	191	197	PF02991	0.376
LIG_LIR_Nem_3	348	354	PF02991	0.431
LIG_LIR_Nem_3	385	391	PF02991	0.423
LIG_LIR_Nem_3	532	537	PF02991	0.415
LIG_LIR_Nem_3	603	607	PF02991	0.457
LIG_LIR_Nem_3	77	82	PF02991	0.312
LIG_LIR_Nem_3	775	781	PF02991	0.369
LIG_LIR_Nem_3	878	883	PF02991	0.322
LIG_LIR_Nem_3	884	889	PF02991	0.332
LIG_LYPXL_S_1	203	207	PF13949	0.381
LIG_LYPXL_SIV_4	437	445	PF13949	0.471
LIG_LYPXL_yS_3	204	207	PF13949	0.376
LIG_PCNA_yPIPBox_3	528	541	PF02747	0.425
LIG_PDZ_Class_3	924	929	PF00595	0.342
LIG_Pex14_1	640	644	PF04695	0.428
LIG_Pex14_2	400	404	PF04695	0.415
LIG_Pex14_3	530	535	PF04695	0.428
LIG_PTB_Apo_2	275	282	PF02174	0.500
LIG_SH2_CRK	388	392	PF00017	0.428
LIG_SH2_CRK	802	806	PF00017	0.492
LIG_SH2_NCK_1	438	442	PF00017	0.415
LIG_SH2_NCK_1	765	769	PF00017	0.469
LIG_SH2_STAP1	36	40	PF00017	0.356
LIG_SH2_STAP1	613	617	PF00017	0.509
LIG_SH2_STAP1	741	745	PF00017	0.359
LIG_SH2_STAP1	781	785	PF00017	0.375
LIG_SH2_STAT5	351	354	PF00017	0.360
LIG_SH2_STAT5	36	39	PF00017	0.269
LIG_SH2_STAT5	371	374	PF00017	0.496
LIG_SH2_STAT5	388	391	PF00017	0.415
LIG_SH2_STAT5	605	608	PF00017	0.402
LIG_SH2_STAT5	620	623	PF00017	0.424
LIG_SH2_STAT5	641	644	PF00017	0.415
LIG_SH2_STAT5	651	654	PF00017	0.415
LIG_SH2_STAT5	746	749	PF00017	0.306
LIG_SH2_STAT5	765	768	PF00017	0.475
LIG_SH2_STAT5	8	11	PF00017	0.427
LIG_SH3_1	375	381	PF00018	0.446
LIG_SH3_1	558	564	PF00018	0.509
LIG_SH3_1	755	761	PF00018	0.496
LIG_SH3_2	378	383	PF14604	0.428
LIG_SH3_2	561	566	PF14604	0.509
LIG_SH3_3	274	280	PF00018	0.272
LIG_SH3_3	375	381	PF00018	0.428
LIG_SH3_3	509	515	PF00018	0.474
LIG_SH3_3	558	564	PF00018	0.476
LIG_SH3_3	633	639	PF00018	0.509
LIG_SH3_3	675	681	PF00018	0.520
LIG_SH3_3	755	761	PF00018	0.470
LIG_SH3_3	916	922	PF00018	0.573
LIG_SUMO_SIM_anti_2	884	891	PF11976	0.375
LIG_SUMO_SIM_par_1	311	319	PF11976	0.469
LIG_SUMO_SIM_par_1	448	453	PF11976	0.512
LIG_SUMO_SIM_par_1	66	72	PF11976	0.325
LIG_SUMO_SIM_par_1	660	665	PF11976	0.387
LIG_SUMO_SIM_par_1	697	704	PF11976	0.389
LIG_SUMO_SIM_par_1	874	881	PF11976	0.262
LIG_SUMO_SIM_par_1	884	891	PF11976	0.348
LIG_TRAF2_1	585	588	PF00917	0.476
LIG_TRAF2_1	754	757	PF00917	0.297
LIG_TYR_ITIM	349	354	PF00017	0.171
LIG_UBA3_1	479	485	PF00899	0.254
LIG_UBA3_1	592	598	PF00899	0.359
LIG_UBA3_1	747	755	PF00899	0.469
LIG_WRC_WIRS_1	253	258	PF05994	0.467
LIG_WRPW_2	197	200	PF00400	0.387
MOD_CDC14_SPxK_1	2	5	PF00782	0.391
MOD_CDC14_SPxK_1	646	649	PF00782	0.252
MOD_CDK_SPxK_1	643	649	PF00069	0.252
MOD_CDK_SPxxK_3	643	650	PF00069	0.252
MOD_CK1_1	225	231	PF00069	0.386
MOD_CK1_1	367	373	PF00069	0.419
MOD_CK1_1	382	388	PF00069	0.280
MOD_CK1_1	87	93	PF00069	0.523
MOD_CK2_1	145	151	PF00069	0.573
MOD_CK2_1	294	300	PF00069	0.501
MOD_CK2_1	411	417	PF00069	0.171
MOD_CK2_1	582	588	PF00069	0.337
MOD_CK2_1	603	609	PF00069	0.357
MOD_CK2_1	784	790	PF00069	0.459
MOD_CK2_1	921	927	PF00069	0.518
MOD_Cter_Amidation	304	307	PF01082	0.370
MOD_Cter_Amidation	845	848	PF01082	0.505
MOD_GlcNHglycan	102	105	PF01048	0.503
MOD_GlcNHglycan	134	137	PF01048	0.490
MOD_GlcNHglycan	296	299	PF01048	0.407
MOD_GlcNHglycan	400	403	PF01048	0.307
MOD_GlcNHglycan	55	58	PF01048	0.530
MOD_GlcNHglycan	584	587	PF01048	0.379
MOD_GlcNHglycan	732	735	PF01048	0.415
MOD_GlcNHglycan	781	784	PF01048	0.504
MOD_GlcNHglycan	853	856	PF01048	0.725
MOD_GSK3_1	132	139	PF00069	0.510
MOD_GSK3_1	34	41	PF00069	0.474
MOD_GSK3_1	411	418	PF00069	0.384
MOD_GSK3_1	425	432	PF00069	0.384
MOD_GSK3_1	511	518	PF00069	0.457
MOD_GSK3_1	578	585	PF00069	0.290
MOD_GSK3_1	639	646	PF00069	0.293
MOD_GSK3_1	700	707	PF00069	0.369
MOD_GSK3_1	735	742	PF00069	0.502
MOD_GSK3_1	851	858	PF00069	0.573
MOD_GSK3_1	921	928	PF00069	0.391
MOD_GSK3_1	94	101	PF00069	0.534
MOD_N-GLC_1	132	137	PF02516	0.533
MOD_N-GLC_1	34	39	PF02516	0.399
MOD_N-GLC_1	367	372	PF02516	0.384
MOD_N-GLC_1	793	798	PF02516	0.420
MOD_N-GLC_1	94	99	PF02516	0.544
MOD_N-GLC_2	725	727	PF02516	0.491
MOD_NEK2_1	189	194	PF00069	0.407
MOD_NEK2_1	398	403	PF00069	0.252
MOD_NEK2_1	42	47	PF00069	0.407
MOD_NEK2_1	425	430	PF00069	0.252
MOD_NEK2_1	739	744	PF00069	0.455
MOD_NEK2_1	764	769	PF00069	0.512
MOD_NEK2_1	793	798	PF00069	0.491
MOD_NEK2_1	890	895	PF00069	0.496
MOD_PIKK_1	74	80	PF00454	0.292
MOD_PKA_2	189	195	PF00069	0.280
MOD_PKA_2	309	315	PF00069	0.374
MOD_PKA_2	364	370	PF00069	0.275
MOD_PKA_2	382	388	PF00069	0.238
MOD_PKA_2	43	49	PF00069	0.434
MOD_PKA_2	897	903	PF00069	0.531
MOD_Plk_1	136	142	PF00069	0.416
MOD_Plk_1	258	264	PF00069	0.533
MOD_Plk_1	291	297	PF00069	0.565
MOD_Plk_1	347	353	PF00069	0.252
MOD_Plk_1	367	373	PF00069	0.123
MOD_Plk_1	38	44	PF00069	0.395
MOD_Plk_1	487	493	PF00069	0.326
MOD_Plk_1	700	706	PF00069	0.425
MOD_Plk_1	735	741	PF00069	0.327
MOD_Plk_1	817	823	PF00069	0.601
MOD_Plk_2-3	279	285	PF00069	0.442
MOD_Plk_2-3	603	609	PF00069	0.328
MOD_Plk_2-3	784	790	PF00069	0.459
MOD_Plk_4	189	195	PF00069	0.346
MOD_Plk_4	21	27	PF00069	0.453
MOD_Plk_4	222	228	PF00069	0.387
MOD_Plk_4	252	258	PF00069	0.532
MOD_Plk_4	347	353	PF00069	0.179
MOD_Plk_4	367	373	PF00069	0.369
MOD_Plk_4	38	44	PF00069	0.450
MOD_Plk_4	4	10	PF00069	0.593
MOD_Plk_4	425	431	PF00069	0.254
MOD_Plk_4	611	617	PF00069	0.384
MOD_Plk_4	774	780	PF00069	0.464
MOD_Plk_4	921	927	PF00069	0.515
MOD_ProDKin_1	511	517	PF00069	0.448
MOD_ProDKin_1	643	649	PF00069	0.299
MOD_SUMO_for_1	754	757	PF00179	0.297
MOD_SUMO_rev_2	390	399	PF00179	0.331
MOD_SUMO_rev_2	810	816	PF00179	0.714
MOD_SUMO_rev_2	818	825	PF00179	0.499
MOD_SUMO_rev_2	844	849	PF00179	0.548
MOD_SUMO_rev_2	94	101	PF00179	0.410
TRG_AP2beta_CARGO_1	532	541	PF09066	0.252
TRG_DiLeu_BaEn_1	532	537	PF01217	0.275
TRG_DiLeu_BaEn_1	775	780	PF01217	0.460
TRG_DiLeu_BaEn_1	885	890	PF01217	0.403
TRG_DiLeu_BaEn_4	532	538	PF01217	0.296
TRG_DiLeu_BaLyEn_6	801	806	PF01217	0.434
TRG_ENDOCYTIC_2	194	197	PF00928	0.377
TRG_ENDOCYTIC_2	204	207	PF00928	0.409
TRG_ENDOCYTIC_2	351	354	PF00928	0.171
TRG_ENDOCYTIC_2	388	391	PF00928	0.284
TRG_ENDOCYTIC_2	613	616	PF00928	0.307
TRG_ENDOCYTIC_2	641	644	PF00928	0.252
TRG_ENDOCYTIC_2	651	654	PF00928	0.252
TRG_ENDOCYTIC_2	802	805	PF00928	0.545
TRG_ER_diArg_1	430	433	PF00400	0.271
TRG_ER_diArg_1	556	558	PF00400	0.371
TRG_ER_diArg_1	648	650	PF00400	0.252
TRG_ER_diArg_1	687	689	PF00400	0.496
TRG_NES_CRM1_1	881	896	PF08389	0.396
TRG_Pf-PMV_PEXEL_1	116	120	PF00026	0.538
TRG_Pf-PMV_PEXEL_1	307	311	PF00026	0.252
TRG_Pf-PMV_PEXEL_1	324	328	PF00026	0.252

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IJ70	Leptomonas seymouri	62%	98%
A0A0S4KIX9	Bodo saltans	37%	100%
A0A1X0NYL5	Trypanosomatidae	41%	96%
A0A3Q8IHX8	Leishmania donovani	81%	99%
A0A422P1Q3	Trypanosoma rangeli	41%	100%
A0JN80	Bos taurus	27%	88%
A4I3A3	Leishmania infantum	81%	99%
D0A7T6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	96%
D0A826	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	99%
E9AZK5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	99%
O14040	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	31%	100%
P0DM58	Arabidopsis thaliana	31%	88%
Q08162	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	93%
Q0P4R5	Xenopus tropicalis	27%	89%
Q0V9R3	Xenopus tropicalis	31%	100%
Q0WPN0	Arabidopsis thaliana	31%	88%
Q4Q8M6	Leishmania major	80%	100%
Q5R5N8	Pongo abelii	28%	88%
Q5U2P0	Rattus norvegicus	28%	88%
Q6GN11	Xenopus laevis	27%	89%
Q8C0S1	Mus musculus	27%	88%
Q8TF46	Homo sapiens	28%	88%
Q9CSH3	Mus musculus	27%	97%
Q9SHL7	Arabidopsis thaliana	28%	100%
Q9Y2L1	Homo sapiens	27%	97%