LeishMANIAdb
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CHAT domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
CHAT domain-containing protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania braziliensis
UniProt:
A4HG78_LEIBR
TriTrypDb:
LbrM.28.0380 , LBRM2903_280009300 *
Length:
125

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HG78
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HG78

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 98 102 PF00656 0.685
CLV_PCSK_SKI1_1 30 34 PF00082 0.439
DEG_Nend_Nbox_1 1 3 PF02207 0.787
DOC_MAPK_DCC_7 7 15 PF00069 0.478
DOC_MAPK_MEF2A_6 7 15 PF00069 0.728
DOC_PP2B_LxvP_1 13 16 PF13499 0.459
DOC_USP7_MATH_1 74 78 PF00917 0.499
DOC_WW_Pin1_4 5 10 PF00397 0.511
DOC_WW_Pin1_4 51 56 PF00397 0.644
LIG_14-3-3_CanoR_1 109 114 PF00244 0.563
LIG_FHA_1 44 50 PF00498 0.664
LIG_FHA_1 66 72 PF00498 0.525
LIG_FHA_2 110 116 PF00498 0.448
LIG_FHA_2 42 48 PF00498 0.650
LIG_LIR_Gen_1 87 94 PF02991 0.716
LIG_LIR_Nem_3 51 56 PF02991 0.682
LIG_LIR_Nem_3 87 92 PF02991 0.556
LIG_PDZ_Class_2 120 125 PF00595 0.538
LIG_Pex14_2 33 37 PF04695 0.673
LIG_SH2_CRK 53 57 PF00017 0.684
MOD_CK1_1 51 57 PF00069 0.689
MOD_CK2_1 109 115 PF00069 0.453
MOD_CK2_1 66 72 PF00069 0.555
MOD_GlcNHglycan 50 53 PF01048 0.637
MOD_GlcNHglycan 68 71 PF01048 0.420
MOD_GSK3_1 37 44 PF00069 0.478
MOD_NEK2_1 37 42 PF00069 0.527
MOD_NEK2_1 48 53 PF00069 0.598
MOD_Plk_1 63 69 PF00069 0.437
MOD_Plk_4 109 115 PF00069 0.672
MOD_ProDKin_1 5 11 PF00069 0.505
MOD_ProDKin_1 51 57 PF00069 0.639
TRG_DiLeu_BaEn_1 88 93 PF01217 0.461
TRG_ENDOCYTIC_2 53 56 PF00928 0.691
TRG_Pf-PMV_PEXEL_1 76 80 PF00026 0.511

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S5H7I7 Leishmania donovani 74% 100%
A4I3C2 Leishmania infantum 74% 100%
E9AZJ8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 78% 100%
Q4Q8N3 Leishmania major 72% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS