Myb-like domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4HG60_LEIBR

TriTrypDb:

LbrM.28.0200 , LBRM2903_280007400

Length:

516

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HG60

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HG60

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	113	115	PF00675	0.595
CLV_NRD_NRD_1	121	123	PF00675	0.662
CLV_NRD_NRD_1	170	172	PF00675	0.791
CLV_NRD_NRD_1	223	225	PF00675	0.685
CLV_NRD_NRD_1	345	347	PF00675	0.633
CLV_NRD_NRD_1	35	37	PF00675	0.684
CLV_NRD_NRD_1	491	493	PF00675	0.618
CLV_PCSK_FUR_1	489	493	PF00082	0.547
CLV_PCSK_KEX2_1	113	115	PF00082	0.595
CLV_PCSK_KEX2_1	170	172	PF00082	0.791
CLV_PCSK_KEX2_1	223	225	PF00082	0.685
CLV_PCSK_KEX2_1	345	347	PF00082	0.633
CLV_PCSK_KEX2_1	356	358	PF00082	0.630
CLV_PCSK_KEX2_1	491	493	PF00082	0.618
CLV_PCSK_PC1ET2_1	356	358	PF00082	0.732
CLV_PCSK_SKI1_1	114	118	PF00082	0.690
CLV_PCSK_SKI1_1	132	136	PF00082	0.549
CLV_PCSK_SKI1_1	284	288	PF00082	0.656
CLV_PCSK_SKI1_1	345	349	PF00082	0.727
CLV_PCSK_SKI1_1	510	514	PF00082	0.734
DEG_APCC_DBOX_1	490	498	PF00400	0.548
DEG_SCF_FBW7_1	175	180	PF00400	0.530
DOC_CKS1_1	10	15	PF01111	0.559
DOC_CKS1_1	174	179	PF01111	0.531
DOC_CYCLIN_RxL_1	109	121	PF00134	0.454
DOC_CYCLIN_RxL_1	353	363	PF00134	0.472
DOC_MAPK_gen_1	489	499	PF00069	0.547
DOC_MAPK_MEF2A_6	492	501	PF00069	0.546
DOC_PP2B_LxvP_1	229	232	PF13499	0.712
DOC_PP2B_LxvP_1	431	434	PF13499	0.536
DOC_PP2B_LxvP_1	499	502	PF13499	0.535
DOC_PP4_FxxP_1	371	374	PF00568	0.495
DOC_PP4_FxxP_1	384	387	PF00568	0.467
DOC_USP7_MATH_1	142	146	PF00917	0.591
DOC_USP7_MATH_1	17	21	PF00917	0.547
DOC_USP7_MATH_1	177	181	PF00917	0.553
DOC_USP7_MATH_1	273	277	PF00917	0.607
DOC_USP7_MATH_1	330	334	PF00917	0.441
DOC_USP7_MATH_1	409	413	PF00917	0.541
DOC_USP7_MATH_1	426	430	PF00917	0.658
DOC_USP7_MATH_1	441	445	PF00917	0.765
DOC_WW_Pin1_4	173	178	PF00397	0.578
DOC_WW_Pin1_4	252	257	PF00397	0.566
DOC_WW_Pin1_4	268	273	PF00397	0.676
DOC_WW_Pin1_4	287	292	PF00397	0.690
DOC_WW_Pin1_4	450	455	PF00397	0.724
DOC_WW_Pin1_4	9	14	PF00397	0.614
LIG_14-3-3_CanoR_1	113	117	PF00244	0.653
LIG_14-3-3_CanoR_1	226	232	PF00244	0.692
LIG_14-3-3_CanoR_1	233	237	PF00244	0.636
LIG_14-3-3_CanoR_1	36	40	PF00244	0.745
LIG_14-3-3_CanoR_1	413	418	PF00244	0.682
LIG_14-3-3_CanoR_1	491	495	PF00244	0.793
LIG_14-3-3_CanoR_1	74	80	PF00244	0.481
LIG_BRCT_BRCA1_1	144	148	PF00533	0.593
LIG_BRCT_BRCA1_1	337	341	PF00533	0.601
LIG_BRCT_BRCA1_1	367	371	PF00533	0.480
LIG_EVH1_1	384	388	PF00568	0.518
LIG_FHA_1	261	267	PF00498	0.549
LIG_FHA_1	50	56	PF00498	0.728
LIG_FHA_2	10	16	PF00498	0.524
LIG_FHA_2	2	8	PF00498	0.535
LIG_LIR_Apic_2	368	374	PF02991	0.554
LIG_LIR_Nem_3	285	289	PF02991	0.675
LIG_LIR_Nem_3	396	400	PF02991	0.525
LIG_MYND_1	237	241	PF01753	0.531
LIG_Pex14_2	148	152	PF04695	0.547
LIG_Pex14_2	367	371	PF04695	0.480
LIG_PTB_Apo_2	29	36	PF02174	0.676
LIG_PTB_Apo_2	391	398	PF02174	0.531
LIG_SH2_STAP1	456	460	PF00017	0.798
LIG_SH2_STAP1	495	499	PF00017	0.733
LIG_SH2_STAP1	94	98	PF00017	0.674
LIG_SH2_STAT3	206	209	PF00017	0.562
LIG_SH2_STAT3	511	514	PF00017	0.508
LIG_SH2_STAT5	511	514	PF00017	0.547
LIG_SH2_STAT5	54	57	PF00017	0.704
LIG_SH3_3	204	210	PF00018	0.716
LIG_SH3_3	21	27	PF00018	0.507
LIG_SH3_3	231	237	PF00018	0.710
LIG_SH3_3	285	291	PF00018	0.582
LIG_SH3_3	376	382	PF00018	0.569
LIG_SH3_3	445	451	PF00018	0.800
LIG_SH3_3	465	471	PF00018	0.775
LIG_SH3_3	7	13	PF00018	0.737
LIG_SUMO_SIM_par_1	502	509	PF11976	0.641
LIG_TRAF2_1	19	22	PF00917	0.707
LIG_TRAF2_1	505	508	PF00917	0.745
MOD_CDK_SPK_2	287	292	PF00069	0.535
MOD_CK1_1	180	186	PF00069	0.757
MOD_CK1_1	260	266	PF00069	0.659
MOD_CK1_1	271	277	PF00069	0.612
MOD_CK1_1	282	288	PF00069	0.455
MOD_CK1_1	290	296	PF00069	0.568
MOD_CK1_1	335	341	PF00069	0.574
MOD_CK1_1	390	396	PF00069	0.710
MOD_CK1_1	412	418	PF00069	0.682
MOD_CK1_1	493	499	PF00069	0.801
MOD_CK2_1	16	22	PF00069	0.697
MOD_CK2_1	188	194	PF00069	0.559
MOD_CK2_1	35	41	PF00069	0.500
MOD_CK2_1	502	508	PF00069	0.755
MOD_CK2_1	87	93	PF00069	0.439
MOD_Cter_Amidation	168	171	PF01082	0.748
MOD_GlcNHglycan	145	148	PF01048	0.610
MOD_GlcNHglycan	202	205	PF01048	0.620
MOD_GlcNHglycan	216	219	PF01048	0.579
MOD_GlcNHglycan	273	276	PF01048	0.747
MOD_GlcNHglycan	367	370	PF01048	0.538
MOD_GlcNHglycan	371	374	PF01048	0.495
MOD_GlcNHglycan	462	465	PF01048	0.577
MOD_GlcNHglycan	85	88	PF01048	0.494
MOD_GlcNHglycan	89	92	PF01048	0.446
MOD_GSK3_1	112	119	PF00069	0.597
MOD_GSK3_1	132	139	PF00069	0.335
MOD_GSK3_1	173	180	PF00069	0.763
MOD_GSK3_1	248	255	PF00069	0.616
MOD_GSK3_1	332	339	PF00069	0.551
MOD_GSK3_1	341	348	PF00069	0.580
MOD_GSK3_1	35	42	PF00069	0.500
MOD_GSK3_1	365	372	PF00069	0.638
MOD_GSK3_1	409	416	PF00069	0.689
MOD_GSK3_1	460	467	PF00069	0.654
MOD_GSK3_1	473	480	PF00069	0.744
MOD_GSK3_1	493	500	PF00069	0.522
MOD_GSK3_1	83	90	PF00069	0.502
MOD_N-GLC_1	282	287	PF02516	0.690
MOD_N-GLC_1	393	398	PF02516	0.529
MOD_NEK2_1	101	106	PF00069	0.517
MOD_NEK2_1	298	303	PF00069	0.547
MOD_NEK2_1	336	341	PF00069	0.594
MOD_NEK2_1	367	372	PF00069	0.562
MOD_NEK2_1	497	502	PF00069	0.540
MOD_NEK2_1	73	78	PF00069	0.552
MOD_NEK2_2	136	141	PF00069	0.550
MOD_NEK2_2	435	440	PF00069	0.812
MOD_PIKK_1	177	183	PF00454	0.807
MOD_PIKK_1	39	45	PF00454	0.512
MOD_PIKK_1	477	483	PF00454	0.677
MOD_PIKK_1	74	80	PF00454	0.406
MOD_PKA_1	345	351	PF00069	0.732
MOD_PKA_2	112	118	PF00069	0.646
MOD_PKA_2	232	238	PF00069	0.650
MOD_PKA_2	345	351	PF00069	0.732
MOD_PKA_2	35	41	PF00069	0.747
MOD_PKA_2	412	418	PF00069	0.759
MOD_PKA_2	490	496	PF00069	0.761
MOD_PKA_2	73	79	PF00069	0.560
MOD_Plk_1	282	288	PF00069	0.568
MOD_Plk_1	39	45	PF00069	0.624
MOD_Plk_1	393	399	PF00069	0.530
MOD_Plk_1	464	470	PF00069	0.537
MOD_Plk_1	49	55	PF00069	0.691
MOD_Plk_4	136	142	PF00069	0.558
MOD_Plk_4	273	279	PF00069	0.570
MOD_Plk_4	336	342	PF00069	0.504
MOD_Plk_4	374	380	PF00069	0.762
MOD_Plk_4	387	393	PF00069	0.565
MOD_Plk_4	426	432	PF00069	0.530
MOD_ProDKin_1	173	179	PF00069	0.579
MOD_ProDKin_1	252	258	PF00069	0.567
MOD_ProDKin_1	268	274	PF00069	0.677
MOD_ProDKin_1	287	293	PF00069	0.691
MOD_ProDKin_1	450	456	PF00069	0.723
MOD_ProDKin_1	9	15	PF00069	0.615
MOD_SUMO_for_1	108	111	PF00179	0.581
MOD_SUMO_for_1	55	58	PF00179	0.740
MOD_SUMO_for_1	80	83	PF00179	0.418
MOD_SUMO_rev_2	505	512	PF00179	0.649
TRG_DiLeu_BaEn_1	320	325	PF01217	0.626
TRG_DiLeu_BaEn_4	50	56	PF01217	0.728
TRG_DiLeu_BaLyEn_6	253	258	PF01217	0.547
TRG_DiLeu_BaLyEn_6	314	319	PF01217	0.493
TRG_DiLeu_BaLyEn_6	61	66	PF01217	0.659
TRG_ER_diArg_1	112	114	PF00400	0.590
TRG_ER_diArg_1	117	120	PF00400	0.624
TRG_ER_diArg_1	223	226	PF00400	0.677

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P724	Leptomonas seymouri	43%	70%
A0A3S7X148	Leishmania donovani	60%	100%
A4I392	Leishmania infantum	60%	100%
E9AZI0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	57%	100%
Q4Q8Q1	Leishmania major	58%	100%