| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | yes | yes: 15 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 12 |
| NetGPI | no | yes: 0, no: 12 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005654 | nucleoplasm | 2 | 1 |
| GO:0005737 | cytoplasm | 2 | 1 |
| GO:0031974 | membrane-enclosed lumen | 2 | 1 |
| GO:0031981 | nuclear lumen | 5 | 1 |
| GO:0032838 | plasma membrane bounded cell projection cytoplasm | 4 | 1 |
| GO:0043233 | organelle lumen | 3 | 1 |
| GO:0070013 | intracellular organelle lumen | 4 | 1 |
| GO:0097014 | ciliary plasm | 5 | 1 |
| GO:0099568 | cytoplasmic region | 3 | 1 |
| GO:0110165 | cellular anatomical entity | 1 | 1 |
Related structures:
AlphaFold database: A4HFY0
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006082 | organic acid metabolic process | 3 | 13 |
| GO:0006520 | amino acid metabolic process | 3 | 13 |
| GO:0006807 | nitrogen compound metabolic process | 2 | 13 |
| GO:0008152 | metabolic process | 1 | 13 |
| GO:0009081 | branched-chain amino acid metabolic process | 4 | 13 |
| GO:0009987 | cellular process | 1 | 13 |
| GO:0019752 | carboxylic acid metabolic process | 5 | 13 |
| GO:0043436 | oxoacid metabolic process | 4 | 13 |
| GO:0044237 | cellular metabolic process | 2 | 13 |
| GO:0044238 | primary metabolic process | 2 | 13 |
| GO:0044281 | small molecule metabolic process | 2 | 13 |
| GO:0071704 | organic substance metabolic process | 2 | 13 |
| GO:1901564 | organonitrogen compound metabolic process | 3 | 13 |
| GO:0008652 | amino acid biosynthetic process | 4 | 2 |
| GO:0009058 | biosynthetic process | 2 | 2 |
| GO:0009082 | branched-chain amino acid biosynthetic process | 5 | 2 |
| GO:0016053 | organic acid biosynthetic process | 4 | 2 |
| GO:0044249 | cellular biosynthetic process | 3 | 2 |
| GO:0044283 | small molecule biosynthetic process | 3 | 2 |
| GO:0046394 | carboxylic acid biosynthetic process | 5 | 2 |
| GO:1901566 | organonitrogen compound biosynthetic process | 4 | 2 |
| GO:1901576 | organic substance biosynthetic process | 3 | 2 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003824 | catalytic activity | 1 | 13 |
| GO:0004084 | branched-chain-amino-acid transaminase activity | 5 | 13 |
| GO:0008483 | transaminase activity | 4 | 13 |
| GO:0016740 | transferase activity | 2 | 13 |
| GO:0016769 | transferase activity, transferring nitrogenous groups | 3 | 13 |
| GO:0052654 | L-leucine transaminase activity | 6 | 9 |
| GO:0052655 | L-valine transaminase activity | 6 | 9 |
| GO:0052656 | L-isoleucine transaminase activity | 6 | 9 |
| GO:0050048 | L-leucine:2-oxoglutarate aminotransferase activity | 5 | 1 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_NRD_NRD_1 | 226 | 228 | PF00675 | 0.281 |
| CLV_NRD_NRD_1 | 237 | 239 | PF00675 | 0.331 |
| CLV_PCSK_KEX2_1 | 228 | 230 | PF00082 | 0.272 |
| CLV_PCSK_PC1ET2_1 | 228 | 230 | PF00082 | 0.371 |
| CLV_PCSK_SKI1_1 | 149 | 153 | PF00082 | 0.371 |
| CLV_PCSK_SKI1_1 | 31 | 35 | PF00082 | 0.377 |
| DEG_Nend_Nbox_1 | 1 | 3 | PF02207 | 0.701 |
| DEG_SCF_FBW7_1 | 183 | 190 | PF00400 | 0.525 |
| DOC_AGCK_PIF_1 | 73 | 78 | PF00069 | 0.291 |
| DOC_ANK_TNKS_1 | 172 | 179 | PF00023 | 0.485 |
| DOC_MAPK_FxFP_2 | 76 | 79 | PF00069 | 0.280 |
| DOC_MAPK_gen_1 | 112 | 120 | PF00069 | 0.562 |
| DOC_MAPK_gen_1 | 362 | 370 | PF00069 | 0.455 |
| DOC_MAPK_JIP1_4 | 217 | 223 | PF00069 | 0.405 |
| DOC_PP1_RVXF_1 | 41 | 48 | PF00149 | 0.462 |
| DOC_PP4_FxxP_1 | 76 | 79 | PF00568 | 0.478 |
| DOC_USP7_MATH_1 | 13 | 17 | PF00917 | 0.636 |
| DOC_USP7_MATH_1 | 185 | 189 | PF00917 | 0.575 |
| DOC_USP7_MATH_1 | 19 | 23 | PF00917 | 0.454 |
| DOC_USP7_MATH_1 | 371 | 375 | PF00917 | 0.312 |
| DOC_USP7_MATH_1 | 80 | 84 | PF00917 | 0.451 |
| DOC_WW_Pin1_4 | 183 | 188 | PF00397 | 0.515 |
| DOC_WW_Pin1_4 | 195 | 200 | PF00397 | 0.437 |
| DOC_WW_Pin1_4 | 351 | 356 | PF00397 | 0.400 |
| DOC_WW_Pin1_4 | 388 | 393 | PF00397 | 0.468 |
| DOC_WW_Pin1_4 | 49 | 54 | PF00397 | 0.381 |
| LIG_APCC_ABBA_1 | 95 | 100 | PF00400 | 0.575 |
| LIG_BRCT_BRCA1_1 | 366 | 370 | PF00533 | 0.275 |
| LIG_EH1_1 | 326 | 334 | PF00400 | 0.478 |
| LIG_eIF4E_1 | 244 | 250 | PF01652 | 0.499 |
| LIG_eIF4E_1 | 327 | 333 | PF01652 | 0.559 |
| LIG_FHA_1 | 150 | 156 | PF00498 | 0.589 |
| LIG_FHA_1 | 27 | 33 | PF00498 | 0.550 |
| LIG_FHA_1 | 288 | 294 | PF00498 | 0.494 |
| LIG_FHA_1 | 347 | 353 | PF00498 | 0.493 |
| LIG_FHA_1 | 80 | 86 | PF00498 | 0.381 |
| LIG_HCF-1_HBM_1 | 165 | 168 | PF13415 | 0.504 |
| LIG_LIR_Apic_2 | 169 | 174 | PF02991 | 0.474 |
| LIG_LIR_Apic_2 | 365 | 369 | PF02991 | 0.439 |
| LIG_LIR_Apic_2 | 62 | 68 | PF02991 | 0.448 |
| LIG_LIR_Gen_1 | 273 | 282 | PF02991 | 0.597 |
| LIG_LIR_LC3C_4 | 349 | 353 | PF02991 | 0.403 |
| LIG_LIR_Nem_3 | 165 | 171 | PF02991 | 0.531 |
| LIG_LIR_Nem_3 | 273 | 279 | PF02991 | 0.599 |
| LIG_LIR_Nem_3 | 316 | 320 | PF02991 | 0.575 |
| LIG_MYND_1 | 37 | 41 | PF01753 | 0.532 |
| LIG_PDZ_Class_2 | 396 | 401 | PF00595 | 0.483 |
| LIG_Pex14_2 | 279 | 283 | PF04695 | 0.474 |
| LIG_Pex14_2 | 47 | 51 | PF04695 | 0.392 |
| LIG_PTB_Apo_2 | 72 | 79 | PF02174 | 0.287 |
| LIG_SH2_CRK | 244 | 248 | PF00017 | 0.504 |
| LIG_SH2_CRK | 259 | 263 | PF00017 | 0.471 |
| LIG_SH2_CRK | 366 | 370 | PF00017 | 0.416 |
| LIG_SH2_NCK_1 | 366 | 370 | PF00017 | 0.343 |
| LIG_SH2_NCK_1 | 98 | 102 | PF00017 | 0.575 |
| LIG_SH2_SRC | 60 | 63 | PF00017 | 0.305 |
| LIG_SH2_SRC | 98 | 101 | PF00017 | 0.575 |
| LIG_SH2_STAP1 | 168 | 172 | PF00017 | 0.474 |
| LIG_SH2_STAP1 | 375 | 379 | PF00017 | 0.476 |
| LIG_SH2_STAT3 | 87 | 90 | PF00017 | 0.389 |
| LIG_SH2_STAT5 | 161 | 164 | PF00017 | 0.493 |
| LIG_SH2_STAT5 | 171 | 174 | PF00017 | 0.495 |
| LIG_SH2_STAT5 | 328 | 331 | PF00017 | 0.477 |
| LIG_SH3_2 | 38 | 43 | PF14604 | 0.525 |
| LIG_SH3_3 | 196 | 202 | PF00018 | 0.474 |
| LIG_SH3_3 | 290 | 296 | PF00018 | 0.546 |
| LIG_SH3_3 | 30 | 36 | PF00018 | 0.461 |
| LIG_SH3_3 | 349 | 355 | PF00018 | 0.464 |
| LIG_SH3_3 | 365 | 371 | PF00018 | 0.250 |
| LIG_SH3_3 | 47 | 53 | PF00018 | 0.518 |
| LIG_SUMO_SIM_par_1 | 246 | 253 | PF11976 | 0.538 |
| LIG_SUMO_SIM_par_1 | 54 | 59 | PF11976 | 0.432 |
| LIG_TRAF2_1 | 335 | 338 | PF00917 | 0.548 |
| LIG_UBA3_1 | 147 | 156 | PF00899 | 0.437 |
| LIG_UBA3_1 | 383 | 390 | PF00899 | 0.464 |
| LIG_WRC_WIRS_1 | 20 | 25 | PF05994 | 0.491 |
| LIG_WW_2 | 37 | 40 | PF00397 | 0.448 |
| MOD_CDK_SPxK_1 | 183 | 189 | PF00069 | 0.525 |
| MOD_CK1_1 | 374 | 380 | PF00069 | 0.344 |
| MOD_CK1_1 | 393 | 399 | PF00069 | 0.523 |
| MOD_CK2_1 | 105 | 111 | PF00069 | 0.403 |
| MOD_CK2_1 | 306 | 312 | PF00069 | 0.570 |
| MOD_CK2_1 | 313 | 319 | PF00069 | 0.532 |
| MOD_Cter_Amidation | 236 | 239 | PF01082 | 0.329 |
| MOD_GlcNHglycan | 10 | 13 | PF01048 | 0.714 |
| MOD_GSK3_1 | 183 | 190 | PF00069 | 0.500 |
| MOD_GSK3_1 | 278 | 285 | PF00069 | 0.584 |
| MOD_GSK3_1 | 287 | 294 | PF00069 | 0.593 |
| MOD_N-GLC_1 | 130 | 135 | PF02516 | 0.203 |
| MOD_N-GLC_1 | 74 | 79 | PF02516 | 0.399 |
| MOD_N-GLC_2 | 278 | 280 | PF02516 | 0.365 |
| MOD_NEK2_1 | 1 | 6 | PF00069 | 0.689 |
| MOD_NEK2_1 | 130 | 135 | PF00069 | 0.492 |
| MOD_NEK2_1 | 297 | 302 | PF00069 | 0.474 |
| MOD_NEK2_1 | 313 | 318 | PF00069 | 0.474 |
| MOD_NEK2_1 | 320 | 325 | PF00069 | 0.575 |
| MOD_NEK2_2 | 187 | 192 | PF00069 | 0.575 |
| MOD_NEK2_2 | 46 | 51 | PF00069 | 0.491 |
| MOD_PIKK_1 | 86 | 92 | PF00454 | 0.455 |
| MOD_PK_1 | 364 | 370 | PF00069 | 0.471 |
| MOD_PKA_2 | 306 | 312 | PF00069 | 0.474 |
| MOD_Plk_1 | 130 | 136 | PF00069 | 0.403 |
| MOD_Plk_1 | 320 | 326 | PF00069 | 0.416 |
| MOD_Plk_1 | 364 | 370 | PF00069 | 0.488 |
| MOD_Plk_1 | 74 | 80 | PF00069 | 0.423 |
| MOD_Plk_4 | 166 | 172 | PF00069 | 0.481 |
| MOD_Plk_4 | 217 | 223 | PF00069 | 0.577 |
| MOD_Plk_4 | 278 | 284 | PF00069 | 0.571 |
| MOD_Plk_4 | 297 | 303 | PF00069 | 0.483 |
| MOD_Plk_4 | 306 | 312 | PF00069 | 0.485 |
| MOD_Plk_4 | 46 | 52 | PF00069 | 0.403 |
| MOD_ProDKin_1 | 183 | 189 | PF00069 | 0.515 |
| MOD_ProDKin_1 | 195 | 201 | PF00069 | 0.437 |
| MOD_ProDKin_1 | 351 | 357 | PF00069 | 0.400 |
| MOD_ProDKin_1 | 388 | 394 | PF00069 | 0.475 |
| MOD_ProDKin_1 | 49 | 55 | PF00069 | 0.376 |
| MOD_SUMO_for_1 | 155 | 158 | PF00179 | 0.411 |
| MOD_SUMO_for_1 | 397 | 400 | PF00179 | 0.570 |
| MOD_SUMO_rev_2 | 11 | 19 | PF00179 | 0.441 |
| MOD_SUMO_rev_2 | 252 | 256 | PF00179 | 0.440 |
| TRG_DiLeu_BaLyEn_6 | 244 | 249 | PF01217 | 0.538 |
| TRG_ENDOCYTIC_2 | 203 | 206 | PF00928 | 0.403 |
| TRG_ENDOCYTIC_2 | 259 | 262 | PF00928 | 0.505 |
| TRG_ENDOCYTIC_2 | 98 | 101 | PF00928 | 0.538 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N1I9J7 | Leptomonas seymouri | 71% | 100% |
| A0A0S4IPR2 | Bodo saltans | 50% | 100% |
| A0A179HME7 | Purpureocillium lilacinum | 25% | 100% |
| A0A1W5T1Y5 | Penicillium oxalicum | 29% | 100% |
| A0A1X0NR31 | Trypanosomatidae | 59% | 100% |
| A0A3Q8IGG4 | Leishmania donovani | 80% | 100% |
| A0A3R7K7G7 | Trypanosoma rangeli | 54% | 100% |
| A0R066 | Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) | 35% | 100% |
| A4I2W8 | Leishmania infantum | 80% | 100% |
| A7SLW1 | Nematostella vectensis | 39% | 99% |
| A9UZ24 | Monosiga brevicollis | 43% | 100% |
| C9K7B6 | Alternaria alternata | 30% | 100% |
| C9K7D8 | Alternaria alternata | 30% | 100% |
| C9ZJG3 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 57% | 100% |
| C9ZJG4 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 57% | 100% |
| E9ADI3 | Leishmania major | 81% | 100% |
| E9AZA7 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 79% | 100% |
| E9AZA9 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 79% | 100% |
| I1R9B6 | Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) | 27% | 100% |
| K0E3V3 | Aspergillus rugulosus | 27% | 100% |
| K7QHS5 | Humulus lupulus | 33% | 98% |
| K7QKH1 | Humulus lupulus | 31% | 100% |
| O14370 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 44% | 94% |
| O15382 | Homo sapiens | 40% | 100% |
| O26004 | Helicobacter pylori (strain ATCC 700392 / 26695) | 28% | 100% |
| O27481 | Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) | 25% | 100% |
| O31461 | Bacillus subtilis (strain 168) | 38% | 100% |
| O32954 | Mycobacterium leprae (strain TN) | 35% | 100% |
| O35854 | Rattus norvegicus | 40% | 100% |
| O35855 | Mus musculus | 41% | 100% |
| O67733 | Aquifex aeolicus (strain VF5) | 24% | 100% |
| O86505 | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) | 36% | 100% |
| P0A1A5 | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) | 25% | 100% |
| P0A1A6 | Salmonella typhi | 25% | 100% |
| P0AB80 | Escherichia coli (strain K12) | 25% | 100% |
| P0AB81 | Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) | 25% | 100% |
| P0AB82 | Escherichia coli O157:H7 | 25% | 100% |
| P24288 | Mus musculus | 40% | 100% |
| P38891 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 39% | 100% |
| P39576 | Bacillus subtilis (strain 168) | 35% | 100% |
| P47176 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 41% | 100% |
| P54687 | Homo sapiens | 40% | 100% |
| P54688 | Caenorhabditis elegans | 40% | 97% |
| P54689 | Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) | 26% | 100% |
| P54690 | Rattus norvegicus | 39% | 98% |
| P54691 | Synechocystis sp. (strain PCC 6803 / Kazusa) | 29% | 100% |
| P63512 | Staphylococcus aureus (strain Mu50 / ATCC 700699) | 37% | 100% |
| P63513 | Staphylococcus aureus (strain MW2) | 37% | 100% |
| P99138 | Staphylococcus aureus (strain N315) | 37% | 100% |
| P9WQ74 | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) | 34% | 100% |
| P9WQ75 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | 34% | 100% |
| Q1RIJ2 | Rickettsia bellii (strain RML369-C) | 24% | 100% |
| Q4ULR3 | Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) | 24% | 100% |
| Q54N47 | Dictyostelium discoideum | 44% | 100% |
| Q5AV02 | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) | 40% | 100% |
| Q5AV04 | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) | 28% | 100% |
| Q5EA40 | Bos taurus | 42% | 100% |
| Q5HIC1 | Staphylococcus aureus (strain COL) | 37% | 100% |
| Q5HRJ8 | Staphylococcus epidermidis (strain ATCC 35984 / RP62A) | 35% | 100% |
| Q5REP0 | Pongo abelii | 40% | 100% |
| Q6GBT3 | Staphylococcus aureus (strain MSSA476) | 37% | 100% |
| Q6GJB4 | Staphylococcus aureus (strain MRSA252) | 36% | 100% |
| Q8CQ78 | Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) | 35% | 100% |
| Q92I26 | Rickettsia conorii (strain ATCC VR-613 / Malish 7) | 24% | 100% |
| Q93Y32 | Arabidopsis thaliana | 29% | 100% |
| Q9FYA6 | Arabidopsis thaliana | 35% | 97% |
| Q9GKM4 | Ovis aries | 39% | 100% |
| Q9LE06 | Arabidopsis thaliana | 26% | 100% |
| Q9LPM8 | Arabidopsis thaliana | 29% | 100% |
| Q9LPM9 | Arabidopsis thaliana | 30% | 100% |
| Q9M401 | Arabidopsis thaliana | 35% | 97% |
| Q9M439 | Arabidopsis thaliana | 30% | 100% |
| Q9Y885 | Cochliobolus carbonum | 23% | 100% |
| Q9ZJF1 | Helicobacter pylori (strain J99 / ATCC 700824) | 29% | 100% |
| S0DS11 | Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) | 25% | 100% |
| S3DQP8 | Glarea lozoyensis (strain ATCC 20868 / MF5171) | 29% | 100% |
| S7ZEI5 | Penicillium oxalicum (strain 114-2 / CGMCC 5302) | 29% | 100% |