Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HFX8_LEIBR

TriTrypDb:

LbrM.27.2190 , LBRM2903_270029000

Length:

557

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HFX8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HFX8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	111	115	PF00656	0.886
CLV_C14_Caspase3-7	504	508	PF00656	0.786
CLV_NRD_NRD_1	150	152	PF00675	0.885
CLV_NRD_NRD_1	171	173	PF00675	0.871
CLV_NRD_NRD_1	296	298	PF00675	0.867
CLV_NRD_NRD_1	338	340	PF00675	0.853
CLV_NRD_NRD_1	471	473	PF00675	0.689
CLV_PCSK_FUR_1	294	298	PF00082	0.866
CLV_PCSK_FUR_1	435	439	PF00082	0.693
CLV_PCSK_FUR_1	469	473	PF00082	0.680
CLV_PCSK_KEX2_1	150	152	PF00082	0.885
CLV_PCSK_KEX2_1	171	173	PF00082	0.871
CLV_PCSK_KEX2_1	296	298	PF00082	0.867
CLV_PCSK_KEX2_1	338	340	PF00082	0.853
CLV_PCSK_KEX2_1	437	439	PF00082	0.695
CLV_PCSK_KEX2_1	471	473	PF00082	0.689
CLV_PCSK_PC1ET2_1	437	439	PF00082	0.695
CLV_PCSK_SKI1_1	437	441	PF00082	0.694
CLV_PCSK_SKI1_1	506	510	PF00082	0.782
DEG_APCC_DBOX_1	470	478	PF00400	0.687
DEG_APCC_DBOX_1	505	513	PF00400	0.779
DEG_APCC_DBOX_1	51	59	PF00400	0.668
DEG_COP1_1	114	122	PF00400	0.884
DOC_MAPK_gen_1	19	26	PF00069	0.679
DOC_MAPK_MEF2A_6	171	180	PF00069	0.874
DOC_MAPK_MEF2A_6	25	33	PF00069	0.650
DOC_PP2B_LxvP_1	323	326	PF13499	0.871
DOC_PP2B_LxvP_1	74	77	PF13499	0.650
DOC_USP7_MATH_1	122	126	PF00917	0.866
DOC_USP7_MATH_1	158	162	PF00917	0.880
DOC_USP7_MATH_1	166	170	PF00917	0.734
DOC_USP7_MATH_1	20	24	PF00917	0.419
DOC_USP7_MATH_1	285	289	PF00917	0.878
DOC_USP7_MATH_1	328	332	PF00917	0.875
DOC_USP7_MATH_1	386	390	PF00917	0.849
DOC_USP7_MATH_1	485	489	PF00917	0.726
DOC_USP7_MATH_1	5	9	PF00917	0.849
DOC_USP7_MATH_1	540	544	PF00917	0.829
DOC_WW_Pin1_4	118	123	PF00397	0.883
DOC_WW_Pin1_4	129	134	PF00397	0.674
DOC_WW_Pin1_4	172	177	PF00397	0.870
DOC_WW_Pin1_4	182	187	PF00397	0.701
DOC_WW_Pin1_4	243	248	PF00397	0.882
DOC_WW_Pin1_4	274	279	PF00397	0.855
DOC_WW_Pin1_4	3	8	PF00397	0.855
DOC_WW_Pin1_4	301	306	PF00397	0.847
DOC_WW_Pin1_4	316	321	PF00397	0.613
LIG_14-3-3_CanoR_1	123	131	PF00244	0.869
LIG_14-3-3_CanoR_1	19	25	PF00244	0.691
LIG_14-3-3_CanoR_1	294	302	PF00244	0.865
LIG_14-3-3_CanoR_1	385	395	PF00244	0.846
LIG_14-3-3_CanoR_1	430	439	PF00244	0.673
LIG_14-3-3_CanoR_1	57	63	PF00244	0.684
LIG_APCC_ABBA_1	84	89	PF00400	0.656
LIG_BRCT_BRCA1_1	291	295	PF00533	0.866
LIG_CtBP_PxDLS_1	280	284	PF00389	0.866
LIG_CtBP_PxDLS_1	368	374	PF00389	0.786
LIG_FHA_1	511	517	PF00498	0.789
LIG_FHA_2	193	199	PF00498	0.884
LIG_FHA_2	413	419	PF00498	0.688
LIG_FHA_2	452	458	PF00498	0.685
LIG_FHA_2	502	508	PF00498	0.789
LIG_Integrin_isoDGR_2	105	107	PF01839	0.871
LIG_LIR_Apic_2	2	7	PF02991	0.855
LIG_LIR_Nem_3	513	518	PF02991	0.796
LIG_PDZ_Class_2	552	557	PF00595	0.820
LIG_SH2_CRK	271	275	PF00017	0.868
LIG_SH2_CRK	342	346	PF00017	0.843
LIG_SH2_CRK	35	39	PF00017	0.627
LIG_SH2_CRK	4	8	PF00017	0.852
LIG_SH2_CRK	533	537	PF00017	0.840
LIG_SH2_NCK_1	300	304	PF00017	0.856
LIG_SH2_NCK_1	342	346	PF00017	0.843
LIG_SH2_NCK_1	4	8	PF00017	0.852
LIG_SH2_SRC	271	274	PF00017	0.869
LIG_SH2_SRC	300	303	PF00017	0.860
LIG_SH2_SRC	515	518	PF00017	0.805
LIG_SH2_STAP1	456	460	PF00017	0.683
LIG_SH2_STAT5	422	425	PF00017	0.667
LIG_SH2_STAT5	515	518	PF00017	0.805
LIG_SH3_2	183	188	PF14604	0.878
LIG_SH3_2	249	254	PF14604	0.803
LIG_SH3_3	116	122	PF00018	0.883
LIG_SH3_3	177	183	PF00018	0.881
LIG_SH3_3	246	252	PF00018	0.797
LIG_SH3_3	275	281	PF00018	0.850
LIG_SH3_3	378	384	PF00018	0.864
LIG_SUMO_SIM_anti_2	89	96	PF11976	0.653
LIG_TRAF2_1	62	65	PF00917	0.673
LIG_TRAF2_2	7	12	PF00917	0.845
LIG_TYR_ITIM	33	38	PF00017	0.633
LIG_TYR_ITSM	511	518	PF00017	0.791
MOD_CDC14_SPxK_1	185	188	PF00782	0.880
MOD_CDK_SPK_2	118	123	PF00069	0.883
MOD_CDK_SPK_2	243	248	PF00069	0.882
MOD_CDK_SPxK_1	182	188	PF00069	0.879
MOD_CK1_1	115	121	PF00069	0.886
MOD_CK1_1	161	167	PF00069	0.883
MOD_CK1_1	224	230	PF00069	0.838
MOD_CK1_1	321	327	PF00069	0.865
MOD_CK1_1	8	14	PF00069	0.848
MOD_CK2_1	295	301	PF00069	0.867
MOD_DYRK1A_RPxSP_1	172	176	PF00069	0.869
MOD_GlcNHglycan	156	159	PF01048	0.878
MOD_GlcNHglycan	164	167	PF01048	0.743
MOD_GlcNHglycan	223	226	PF01048	0.827
MOD_GlcNHglycan	240	243	PF01048	0.583
MOD_GlcNHglycan	258	261	PF01048	0.569
MOD_GlcNHglycan	287	290	PF01048	0.869
MOD_GlcNHglycan	323	326	PF01048	0.871
MOD_GlcNHglycan	332	335	PF01048	0.710
MOD_GlcNHglycan	365	368	PF01048	0.874
MOD_GlcNHglycan	388	391	PF01048	0.841
MOD_GlcNHglycan	404	407	PF01048	0.505
MOD_GlcNHglycan	46	49	PF01048	0.644
MOD_GlcNHglycan	546	549	PF01048	0.834
MOD_GSK3_1	118	125	PF00069	0.877
MOD_GSK3_1	127	134	PF00069	0.709
MOD_GSK3_1	154	161	PF00069	0.880
MOD_GSK3_1	162	169	PF00069	0.740
MOD_GSK3_1	220	227	PF00069	0.825
MOD_GSK3_1	285	292	PF00069	0.876
MOD_GSK3_1	3	10	PF00069	0.853
MOD_GSK3_1	301	308	PF00069	0.564
MOD_GSK3_1	328	335	PF00069	0.871
MOD_GSK3_1	363	370	PF00069	0.787
MOD_GSK3_1	398	405	PF00069	0.815
MOD_GSK3_1	483	490	PF00069	0.721
MOD_GSK3_1	540	547	PF00069	0.831
MOD_N-GLC_1	214	219	PF02516	0.844
MOD_N-GLC_1	349	354	PF02516	0.851
MOD_N-GLC_1	483	488	PF02516	0.708
MOD_N-GLC_2	360	362	PF02516	0.872
MOD_NEK2_1	162	167	PF00069	0.883
MOD_NEK2_1	214	219	PF00069	0.844
MOD_NEK2_1	221	226	PF00069	0.702
MOD_NEK2_1	295	300	PF00069	0.867
MOD_NEK2_1	349	354	PF00069	0.851
MOD_NEK2_1	451	456	PF00069	0.681
MOD_NEK2_2	20	25	PF00069	0.677
MOD_NEK2_2	501	506	PF00069	0.791
MOD_PIKK_1	261	267	PF00454	0.875
MOD_PIKK_1	369	375	PF00454	0.873
MOD_PIKK_1	5	11	PF00454	0.846
MOD_PKA_1	296	302	PF00069	0.865
MOD_PKA_1	437	443	PF00069	0.695
MOD_PKA_2	106	112	PF00069	0.880
MOD_PKA_2	122	128	PF00069	0.586
MOD_PKA_2	20	26	PF00069	0.665
MOD_PKA_2	253	259	PF00069	0.893
MOD_PKA_2	285	291	PF00069	0.835
MOD_PKA_2	295	301	PF00069	0.736
MOD_PKA_2	437	443	PF00069	0.695
MOD_PKA_2	44	50	PF00069	0.660
MOD_PKA_2	540	546	PF00069	0.830
MOD_PKA_2	56	62	PF00069	0.476
MOD_PKB_1	294	302	PF00069	0.865
MOD_PKB_1	383	391	PF00069	0.853
MOD_Plk_1	214	220	PF00069	0.839
MOD_Plk_1	451	457	PF00069	0.682
MOD_Plk_1	483	489	PF00069	0.716
MOD_Plk_1	551	557	PF00069	0.821
MOD_Plk_2-3	412	418	PF00069	0.690
MOD_Plk_2-3	551	557	PF00069	0.821
MOD_Plk_4	412	418	PF00069	0.690
MOD_Plk_4	487	493	PF00069	0.757
MOD_ProDKin_1	118	124	PF00069	0.877
MOD_ProDKin_1	129	135	PF00069	0.674
MOD_ProDKin_1	172	178	PF00069	0.872
MOD_ProDKin_1	182	188	PF00069	0.704
MOD_ProDKin_1	243	249	PF00069	0.883
MOD_ProDKin_1	274	280	PF00069	0.850
MOD_ProDKin_1	3	9	PF00069	0.855
MOD_ProDKin_1	301	307	PF00069	0.845
MOD_ProDKin_1	316	322	PF00069	0.611
TRG_DiLeu_BaEn_3	64	70	PF01217	0.651
TRG_ENDOCYTIC_2	35	38	PF00928	0.628
TRG_ENDOCYTIC_2	515	518	PF00928	0.805
TRG_ENDOCYTIC_2	533	536	PF00928	0.525
TRG_ER_diArg_1	149	151	PF00400	0.881
TRG_ER_diArg_1	18	21	PF00400	0.767
TRG_ER_diArg_1	24	27	PF00400	0.523
TRG_ER_diArg_1	283	286	PF00400	0.839
TRG_ER_diArg_1	295	297	PF00400	0.715
TRG_ER_diArg_1	382	385	PF00400	0.867
TRG_Pf-PMV_PEXEL_1	465	470	PF00026	0.668
TRG_Pf-PMV_PEXEL_1	472	476	PF00026	0.567