F-box only protein 22

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HFR7_LEIBR

TriTrypDb:

LbrM.27.1540 , LBRM2903_270021000

Length:

143


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Could not find GO cellular_component term for this entry.

A4HFR7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HFR7


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	51	55	PF00656	0.425
CLV_NRD_NRD_1	85	87	PF00675	0.452
CLV_PCSK_SKI1_1	123	127	PF00082	0.425
CLV_PCSK_SKI1_1	3	7	PF00082	0.495
CLV_PCSK_SKI1_1	53	57	PF00082	0.433
DEG_APCC_DBOX_1	122	130	PF00400	0.422
DOC_MAPK_MEF2A_6	119	126	PF00069	0.414
DOC_PIKK_1	83	91	PF02985	0.534
LIG_14-3-3_CanoR_1	3	8	PF00244	0.471
LIG_BIR_II_1	1	5	PF00653	0.506
LIG_eIF4E_1	111	117	PF01652	0.454
LIG_FHA_1	4	10	PF00498	0.448
LIG_FHA_2	8	14	PF00498	0.406
LIG_LIR_Apic_2	10	14	PF02991	0.419
LIG_LIR_Nem_3	54	60	PF02991	0.427
LIG_LIR_Nem_3	82	88	PF02991	0.423
LIG_NRBOX	4	10	PF00104	0.384
LIG_PCNA_PIPBox_1	101	110	PF02747	0.444
LIG_SH2_CRK	57	61	PF00017	0.437
LIG_SH2_CRK	85	89	PF00017	0.438
LIG_SH2_NCK_1	11	15	PF00017	0.438
LIG_SH2_NCK_1	111	115	PF00017	0.468
LIG_SH2_SRC	11	14	PF00017	0.429
LIG_SH2_STAP1	72	76	PF00017	0.369
LIG_SUMO_SIM_par_1	5	10	PF11976	0.380
LIG_UBA3_1	63	67	PF00899	0.567
MOD_CK1_1	135	141	PF00069	0.743
MOD_CK2_1	29	35	PF00069	0.344
MOD_GlcNHglycan	137	140	PF01048	0.612
MOD_GSK3_1	135	142	PF00069	0.707
MOD_GSK3_1	3	10	PF00069	0.464
MOD_N-GLC_1	48	53	PF02516	0.487
MOD_NEK2_1	56	61	PF00069	0.418
MOD_NEK2_1	91	96	PF00069	0.616
MOD_NEK2_2	37	42	PF00069	0.483
MOD_PK_1	29	35	PF00069	0.428
MOD_PKA_2	135	141	PF00069	0.691
MOD_Plk_1	29	35	PF00069	0.451
MOD_Plk_4	29	35	PF00069	0.451
MOD_Plk_4	3	9	PF00069	0.450
TRG_ENDOCYTIC_2	111	114	PF00928	0.474
TRG_ENDOCYTIC_2	57	60	PF00928	0.431
TRG_ENDOCYTIC_2	85	88	PF00928	0.424
TRG_NES_CRM1_1	54	70	PF08389	0.471


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5C5	Leptomonas seymouri	84%	99%
A0A1X0P4D7	Trypanosomatidae	75%	100%
A0A3Q8IGC5	Leishmania donovani	91%	99%
A0A422NFQ4	Trypanosoma rangeli	73%	100%
A4I2U2	Leishmania infantum	91%	99%
D0A608	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	70%	100%
E9ADC1	Leishmania major	90%	100%
E9AZ45	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	99%