| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | yes | yes: 30 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 7 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 21 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 14 |
| NetGPI | no | yes: 0, no: 14 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005840 | ribosome | 5 | 14 |
| GO:0032991 | protein-containing complex | 1 | 15 |
| GO:0043226 | organelle | 2 | 14 |
| GO:0043228 | non-membrane-bounded organelle | 3 | 14 |
| GO:0043229 | intracellular organelle | 3 | 14 |
| GO:0043232 | intracellular non-membrane-bounded organelle | 4 | 14 |
| GO:0110165 | cellular anatomical entity | 1 | 15 |
| GO:1990904 | ribonucleoprotein complex | 2 | 15 |
| GO:0005737 | cytoplasm | 2 | 1 |
| GO:0015934 | large ribosomal subunit | 4 | 1 |
| GO:0022625 | cytosolic large ribosomal subunit | 5 | 1 |
| GO:0044391 | ribosomal subunit | 3 | 1 |
Related structures:
AlphaFold database: A4HFR5
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0009987 | cellular process | 1 | 15 |
| GO:0022613 | ribonucleoprotein complex biogenesis | 4 | 14 |
| GO:0042254 | ribosome biogenesis | 5 | 14 |
| GO:0044085 | cellular component biogenesis | 3 | 14 |
| GO:0071840 | cellular component organization or biogenesis | 2 | 15 |
| GO:0000027 | ribosomal large subunit assembly | 7 | 1 |
| GO:0002181 | cytoplasmic translation | 5 | 1 |
| GO:0006412 | translation | 4 | 1 |
| GO:0006518 | peptide metabolic process | 4 | 1 |
| GO:0006807 | nitrogen compound metabolic process | 2 | 1 |
| GO:0008152 | metabolic process | 1 | 1 |
| GO:0009058 | biosynthetic process | 2 | 1 |
| GO:0009059 | macromolecule biosynthetic process | 4 | 1 |
| GO:0016043 | cellular component organization | 3 | 1 |
| GO:0019538 | protein metabolic process | 3 | 1 |
| GO:0022607 | cellular component assembly | 4 | 1 |
| GO:0022618 | ribonucleoprotein complex assembly | 6 | 1 |
| GO:0034641 | cellular nitrogen compound metabolic process | 3 | 1 |
| GO:0034645 | obsolete cellular macromolecule biosynthetic process | 4 | 1 |
| GO:0043043 | peptide biosynthetic process | 5 | 1 |
| GO:0043170 | macromolecule metabolic process | 3 | 1 |
| GO:0043603 | amide metabolic process | 3 | 1 |
| GO:0043604 | amide biosynthetic process | 4 | 1 |
| GO:0043933 | protein-containing complex organization | 4 | 1 |
| GO:0044237 | cellular metabolic process | 2 | 1 |
| GO:0044238 | primary metabolic process | 2 | 1 |
| GO:0044249 | cellular biosynthetic process | 3 | 1 |
| GO:0044260 | obsolete cellular macromolecule metabolic process | 3 | 1 |
| GO:0044271 | cellular nitrogen compound biosynthetic process | 4 | 1 |
| GO:0065003 | protein-containing complex assembly | 5 | 1 |
| GO:0071704 | organic substance metabolic process | 2 | 1 |
| GO:0071826 | ribonucleoprotein complex subunit organization | 5 | 1 |
| GO:1901564 | organonitrogen compound metabolic process | 3 | 1 |
| GO:1901566 | organonitrogen compound biosynthetic process | 4 | 1 |
| GO:1901576 | organic substance biosynthetic process | 3 | 1 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | 3 | 1 |
| GO:0003723 | RNA binding | 4 | 1 |
| GO:0003735 | structural constituent of ribosome | 2 | 1 |
| GO:0005198 | structural molecule activity | 1 | 1 |
| GO:0005488 | binding | 1 | 1 |
| GO:0019843 | rRNA binding | 5 | 1 |
| GO:0070180 | large ribosomal subunit rRNA binding | 6 | 1 |
| GO:0097159 | organic cyclic compound binding | 2 | 1 |
| GO:1901363 | heterocyclic compound binding | 2 | 1 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_C14_Caspase3-7 | 172 | 176 | PF00656 | 0.479 |
| CLV_NRD_NRD_1 | 42 | 44 | PF00675 | 0.296 |
| CLV_PCSK_KEX2_1 | 42 | 44 | PF00082 | 0.279 |
| CLV_PCSK_KEX2_1 | 8 | 10 | PF00082 | 0.288 |
| CLV_PCSK_PC1ET2_1 | 8 | 10 | PF00082 | 0.288 |
| CLV_PCSK_SKI1_1 | 106 | 110 | PF00082 | 0.219 |
| CLV_PCSK_SKI1_1 | 153 | 157 | PF00082 | 0.314 |
| CLV_PCSK_SKI1_1 | 165 | 169 | PF00082 | 0.240 |
| CLV_PCSK_SKI1_1 | 202 | 206 | PF00082 | 0.427 |
| CLV_PCSK_SKI1_1 | 253 | 257 | PF00082 | 0.279 |
| CLV_PCSK_SKI1_1 | 42 | 46 | PF00082 | 0.374 |
| DOC_CYCLIN_RxL_1 | 250 | 259 | PF00134 | 0.479 |
| DOC_MAPK_gen_1 | 153 | 161 | PF00069 | 0.479 |
| DOC_MAPK_MEF2A_6 | 21 | 30 | PF00069 | 0.547 |
| DOC_MAPK_MEF2A_6 | 253 | 260 | PF00069 | 0.554 |
| DOC_PP1_RVXF_1 | 200 | 207 | PF00149 | 0.427 |
| DOC_PP2B_PxIxI_1 | 1 | 7 | PF00149 | 0.432 |
| DOC_USP7_MATH_1 | 131 | 135 | PF00917 | 0.547 |
| DOC_USP7_MATH_1 | 290 | 294 | PF00917 | 0.535 |
| DOC_USP7_MATH_1 | 298 | 302 | PF00917 | 0.571 |
| DOC_USP7_UBL2_3 | 61 | 65 | PF12436 | 0.494 |
| DOC_WW_Pin1_4 | 185 | 190 | PF00397 | 0.526 |
| DOC_WW_Pin1_4 | 70 | 75 | PF00397 | 0.495 |
| LIG_BRCT_BRCA1_1 | 262 | 266 | PF00533 | 0.585 |
| LIG_FHA_1 | 176 | 182 | PF00498 | 0.585 |
| LIG_FHA_1 | 212 | 218 | PF00498 | 0.364 |
| LIG_FHA_1 | 260 | 266 | PF00498 | 0.568 |
| LIG_FHA_1 | 91 | 97 | PF00498 | 0.499 |
| LIG_FHA_2 | 133 | 139 | PF00498 | 0.479 |
| LIG_FHA_2 | 205 | 211 | PF00498 | 0.503 |
| LIG_GBD_Chelix_1 | 150 | 158 | PF00786 | 0.385 |
| LIG_IRF3_LxIS_1 | 181 | 188 | PF10401 | 0.479 |
| LIG_LIR_Gen_1 | 142 | 151 | PF02991 | 0.479 |
| LIG_LIR_Gen_1 | 20 | 30 | PF02991 | 0.500 |
| LIG_LIR_Nem_3 | 142 | 148 | PF02991 | 0.479 |
| LIG_LIR_Nem_3 | 188 | 194 | PF02991 | 0.373 |
| LIG_LIR_Nem_3 | 20 | 25 | PF02991 | 0.488 |
| LIG_LIR_Nem_3 | 250 | 255 | PF02991 | 0.479 |
| LIG_NBox_RRM_1 | 144 | 154 | PF00076 | 0.479 |
| LIG_PCNA_yPIPBox_3 | 193 | 202 | PF02747 | 0.376 |
| LIG_SH2_CRK | 22 | 26 | PF00017 | 0.488 |
| LIG_SH2_SRC | 11 | 14 | PF00017 | 0.419 |
| LIG_SH2_STAP1 | 11 | 15 | PF00017 | 0.488 |
| LIG_SH2_STAP1 | 22 | 26 | PF00017 | 0.488 |
| LIG_SH2_STAT5 | 264 | 267 | PF00017 | 0.436 |
| LIG_SH3_3 | 111 | 117 | PF00018 | 0.426 |
| LIG_SH3_3 | 125 | 131 | PF00018 | 0.495 |
| LIG_SUMO_SIM_par_1 | 157 | 164 | PF11976 | 0.479 |
| LIG_SUMO_SIM_par_1 | 195 | 201 | PF11976 | 0.518 |
| LIG_SUMO_SIM_par_1 | 254 | 259 | PF11976 | 0.585 |
| LIG_TYR_ITSM | 18 | 25 | PF00017 | 0.488 |
| MOD_CDK_SPxxK_3 | 70 | 77 | PF00069 | 0.495 |
| MOD_CK1_1 | 177 | 183 | PF00069 | 0.479 |
| MOD_CK1_1 | 259 | 265 | PF00069 | 0.479 |
| MOD_CK1_1 | 309 | 315 | PF00069 | 0.458 |
| MOD_CK1_1 | 90 | 96 | PF00069 | 0.530 |
| MOD_CK2_1 | 132 | 138 | PF00069 | 0.479 |
| MOD_Cter_Amidation | 53 | 56 | PF01082 | 0.279 |
| MOD_GlcNHglycan | 240 | 243 | PF01048 | 0.417 |
| MOD_GlcNHglycan | 279 | 282 | PF01048 | 0.388 |
| MOD_GlcNHglycan | 287 | 290 | PF01048 | 0.359 |
| MOD_GlcNHglycan | 292 | 295 | PF01048 | 0.329 |
| MOD_GlcNHglycan | 301 | 304 | PF01048 | 0.346 |
| MOD_GlcNHglycan | 89 | 92 | PF01048 | 0.396 |
| MOD_GSK3_1 | 256 | 263 | PF00069 | 0.585 |
| MOD_N-GLC_1 | 175 | 180 | PF02516 | 0.279 |
| MOD_N-GLC_1 | 185 | 190 | PF02516 | 0.326 |
| MOD_N-GLC_1 | 70 | 75 | PF02516 | 0.269 |
| MOD_NEK2_1 | 256 | 261 | PF00069 | 0.479 |
| MOD_NEK2_1 | 279 | 284 | PF00069 | 0.521 |
| MOD_OFUCOSY | 18 | 24 | PF10250 | 0.347 |
| MOD_PIKK_1 | 137 | 143 | PF00454 | 0.585 |
| MOD_PIKK_1 | 32 | 38 | PF00454 | 0.479 |
| MOD_Plk_2-3 | 195 | 201 | PF00069 | 0.287 |
| MOD_Plk_4 | 140 | 146 | PF00069 | 0.514 |
| MOD_Plk_4 | 177 | 183 | PF00069 | 0.479 |
| MOD_Plk_4 | 195 | 201 | PF00069 | 0.370 |
| MOD_Plk_4 | 260 | 266 | PF00069 | 0.462 |
| MOD_Plk_4 | 279 | 285 | PF00069 | 0.441 |
| MOD_ProDKin_1 | 185 | 191 | PF00069 | 0.530 |
| MOD_ProDKin_1 | 70 | 76 | PF00069 | 0.495 |
| MOD_SUMO_for_1 | 305 | 308 | PF00179 | 0.582 |
| MOD_SUMO_for_1 | 7 | 10 | PF00179 | 0.424 |
| MOD_SUMO_rev_2 | 100 | 108 | PF00179 | 0.419 |
| MOD_SUMO_rev_2 | 160 | 168 | PF00179 | 0.479 |
| TRG_DiLeu_BaEn_1 | 84 | 89 | PF01217 | 0.585 |
| TRG_DiLeu_BaEn_4 | 84 | 90 | PF01217 | 0.547 |
| TRG_ENDOCYTIC_2 | 191 | 194 | PF00928 | 0.375 |
| TRG_ENDOCYTIC_2 | 22 | 25 | PF00928 | 0.503 |
| TRG_ER_diArg_1 | 41 | 43 | PF00400 | 0.479 |
| TRG_Pf-PMV_PEXEL_1 | 220 | 224 | PF00026 | 0.429 |
| TRG_Pf-PMV_PEXEL_1 | 272 | 276 | PF00026 | 0.385 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P2F2 | Leptomonas seymouri | 82% | 100% |
| A0A1X0P470 | Trypanosomatidae | 70% | 100% |
| A0A1X0P504 | Trypanosomatidae | 70% | 100% |
| A0A3Q8IDC2 | Leishmania donovani | 89% | 100% |
| A0A3S7X0P4 | Leishmania donovani | 89% | 100% |
| A0A3S7XBL0 | Leishmania donovani | 23% | 100% |
| A0A422NFR1 | Trypanosoma rangeli | 71% | 99% |
| A3DNI2 | Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1) | 26% | 96% |
| A4FZS8 | Methanococcus maripaludis (strain C5 / ATCC BAA-1333) | 28% | 96% |
| A4HFR6 | Leishmania braziliensis | 100% | 100% |
| A4HPY2 | Leishmania braziliensis | 24% | 100% |
| A4I2U1 | Leishmania infantum | 89% | 100% |
| A4IDP3 | Leishmania infantum | 23% | 100% |
| A5UKU8 | Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS) | 28% | 96% |
| A6UTF8 | Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3) | 28% | 96% |
| A6VIP9 | Methanococcus maripaludis (strain C7 / ATCC BAA-1331) | 31% | 96% |
| A8ABQ7 | Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125) | 26% | 93% |
| A9A838 | Methanococcus maripaludis (strain C6 / ATCC BAA-1332) | 30% | 96% |
| B0R4W1 | Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) | 30% | 92% |
| B6YSX9 | Thermococcus onnurineus (strain NA1) | 29% | 95% |
| C3MR85 | Sulfolobus islandicus (strain L.S.2.15 / Lassen #1) | 25% | 96% |
| C3MXH4 | Sulfolobus islandicus (strain M.14.25 / Kamchatka #1) | 25% | 96% |
| C3MZC0 | Sulfolobus islandicus (strain M.16.27) | 26% | 96% |
| C3N7E1 | Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1) | 25% | 96% |
| C3NG93 | Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2) | 25% | 96% |
| C4KIJ9 | Sulfolobus islandicus (strain M.16.4 / Kamchatka #3) | 25% | 96% |
| C5A428 | Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3) | 27% | 95% |
| C6A1F5 | Thermococcus sibiricus (strain DSM 12597 / MM 739) | 31% | 96% |
| D0A606 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 68% | 99% |
| D0A607 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 68% | 99% |
| E8NHJ8 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 88% | 100% |
| E9ADB9 | Leishmania major | 88% | 100% |
| E9ATP9 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 24% | 100% |
| G0S616 | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | 25% | 100% |
| O04204 | Arabidopsis thaliana | 44% | 100% |
| O24573 | Zea mays | 43% | 100% |
| O27717 | Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) | 27% | 96% |
| O52705 | Methanothermococcus thermolithotrophicus | 29% | 96% |
| O74109 | Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) | 27% | 94% |
| O74864 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 42% | 100% |
| P05317 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 42% | 100% |
| P05388 | Homo sapiens | 41% | 100% |
| P13553 | Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) | 30% | 92% |
| P14869 | Mus musculus | 41% | 100% |
| P15825 | Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) | 27% | 93% |
| P15826 | Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB) | 30% | 96% |
| P19889 | Drosophila melanogaster | 39% | 100% |
| P19945 | Rattus norvegicus | 41% | 100% |
| P22685 | Dictyostelium discoideum | 42% | 100% |
| P26796 | Trypanosoma cruzi | 68% | 100% |
| P29764 | Oxybasis rubra | 42% | 100% |
| P33201 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 27% | 100% |
| P35023 | Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) | 27% | 96% |
| P39096 | Leishmania chagasi | 88% | 100% |
| P39097 | Leishmania infantum | 87% | 100% |
| P41095 | Oryza sativa subsp. japonica | 42% | 100% |
| P41198 | Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) | 29% | 93% |
| P47826 | Gallus gallus | 42% | 100% |
| P50345 | Lupinus luteus | 42% | 100% |
| P50346 | Glycine max | 45% | 100% |
| P54049 | Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) | 26% | 96% |
| P57691 | Arabidopsis thaliana | 42% | 100% |
| P57692 | Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) | 24% | 100% |
| P96039 | Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) | 26% | 96% |
| Q12UP8 | Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M) | 24% | 96% |
| Q29214 | Sus scrofa | 41% | 100% |
| Q2NEW2 | Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3) | 25% | 97% |
| Q3INI7 | Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB 2260 / Gabara) | 29% | 91% |
| Q42112 | Arabidopsis thaliana | 42% | 100% |
| Q46EU9 | Methanosarcina barkeri (strain Fusaro / DSM 804) | 26% | 93% |
| Q4Q0U9 | Leishmania major | 24% | 100% |
| Q5JH36 | Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) | 28% | 95% |
| Q6L1X8 | Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828) | 21% | 100% |
| Q6M0L1 | Methanococcus maripaludis (strain S2 / LL) | 30% | 96% |
| Q75DK9 | Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) | 24% | 100% |
| Q7S302 | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) | 26% | 100% |
| Q8NHW5 | Homo sapiens | 41% | 100% |
| Q8PY51 | Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) | 26% | 93% |
| Q8SRJ7 | Encephalitozoon cuniculi (strain GB-M1) | 38% | 100% |
| Q8TI80 | Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) | 27% | 93% |
| Q8TX50 | Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) | 30% | 90% |
| Q8TZJ8 | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) | 28% | 95% |
| Q90YX1 | Ictalurus punctatus | 41% | 100% |
| Q93572 | Caenorhabditis elegans | 41% | 100% |
| Q94660 | Plasmodium falciparum (isolate 7G8) | 42% | 100% |
| Q95140 | Bos taurus | 41% | 100% |
| Q967Y7 | Eimeria tenella | 36% | 100% |
| Q96TJ5 | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) | 39% | 100% |
| Q971J2 | Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) | 26% | 97% |
| Q97BN3 | Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1) | 25% | 100% |
| Q9C3Z6 | Podospora anserina | 39% | 100% |
| Q9DG68 | Lithobates sylvaticus | 41% | 100% |
| Q9PV90 | Danio rerio | 40% | 100% |
| Q9U3U0 | Ceratitis capitata | 40% | 100% |
| Q9UXS5 | Pyrococcus abyssi (strain GE5 / Orsay) | 28% | 95% |
| Q9Y8J3 | Methanococcus voltae | 30% | 100% |
| V5BL26 | Trypanosoma cruzi | 67% | 99% |