LeishMANIAdb
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S1-like domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
S1-like domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HFP2_LEIBR
TriTrypDb:
LbrM.27.1270 , LBRM2903_270018600
Length:
245

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HFP2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HFP2

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 199 203 PF00656 0.759
CLV_NRD_NRD_1 104 106 PF00675 0.621
CLV_NRD_NRD_1 5 7 PF00675 0.652
CLV_PCSK_SKI1_1 11 15 PF00082 0.611
CLV_PCSK_SKI1_1 162 166 PF00082 0.763
CLV_PCSK_SKI1_1 219 223 PF00082 0.700
CLV_PCSK_SKI1_1 45 49 PF00082 0.593
DEG_APCC_DBOX_1 161 169 PF00400 0.767
DEG_SPOP_SBC_1 175 179 PF00917 0.657
DEG_SPOP_SBC_1 50 54 PF00917 0.558
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P6I4 Leptomonas seymouri 58% 97%
A0A3Q8IEC6 Leishmania donovani 80% 100%
A0A3R7MDN0 Trypanosoma rangeli 43% 100%
A4I2R8 Leishmania infantum 80% 100%
D0A5X3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 40% 100%
E9AD95 Leishmania major 82% 100%
E9AZ20 Leishmania mexicana (strain MHOM/GT/2001/U1103) 79% 100%
V5B8N2 Trypanosoma cruzi 43% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS