Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HFM2_LEIBR

TriTrypDb:

LbrM.27.1070 , LBRM2903_270016600

Length:

281

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HFM2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HFM2

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	253	255	PF00675	0.707
CLV_NRD_NRD_1	259	261	PF00675	0.709
CLV_NRD_NRD_1	35	37	PF00675	0.614
CLV_NRD_NRD_1	4	6	PF00675	0.553
CLV_PCSK_KEX2_1	253	255	PF00082	0.707
CLV_PCSK_KEX2_1	33	35	PF00082	0.614
CLV_PCSK_PC1ET2_1	33	35	PF00082	0.569
CLV_PCSK_SKI1_1	36	40	PF00082	0.622
CLV_PCSK_SKI1_1	87	91	PF00082	0.516
DEG_COP1_1	264	273	PF00400	0.630

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6J0	Leptomonas seymouri	46%	100%
A0A1X0P427	Trypanosomatidae	35%	100%
A0A3S7X0L8	Leishmania donovani	73%	100%
A0A422N2W4	Trypanosoma rangeli	30%	100%
A4I2Q0	Leishmania infantum	73%	100%
D0A5V2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
E9AD76	Leishmania major	73%	100%
E9AZ00	Leishmania mexicana (strain MHOM/GT/2001/U1103)	74%	100%

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