Putative 2-oxoglutarate dehydrogenase subunit

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

2-oxoglutarate dehydrogenase subunit, putative

Species:

Leishmania braziliensis

UniProt:

A4HFL1_LEIBR

TriTrypDb:

LbrM.27.0960 , LBRM2903_270015500

Length:

1007

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 45

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 24

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 2, no: 15
NetGPI	no	yes: 0, no: 17

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0005739	mitochondrion	5	2
GO:0005929	cilium	4	1
GO:0032991	protein-containing complex	1	2
GO:0042995	cell projection	2	1
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0045239	tricarboxylic acid cycle enzyme complex	3	2
GO:0045240	dihydrolipoyl dehydrogenase complex	4	2
GO:0045252	oxoglutarate dehydrogenase complex	4	2
GO:0110165	cellular anatomical entity	1	2
GO:0120025	plasma membrane bounded cell projection	3	1
GO:1902494	catalytic complex	2	2
GO:1990204	oxidoreductase complex	3	2
GO:1990234	transferase complex	3	2
GO:0005815	microtubule organizing center	2	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0036064	ciliary basal body	3	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1

Expansion

Sequence features

A4HFL1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HFL1

Function

Biological processes
Term	Name	Level	Count
GO:0006099	tricarboxylic acid cycle	3	18
GO:0008152	metabolic process	1	18
GO:0044238	primary metabolic process	2	18

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	18
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	5	18
GO:0005488	binding	1	18
GO:0016491	oxidoreductase activity	2	18
GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	4	18
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	3	18
GO:0019842	vitamin binding	3	18
GO:0030976	thiamine pyrophosphate binding	3	18
GO:0036094	small molecule binding	2	18
GO:0043167	ion binding	2	18
GO:0043168	anion binding	3	18
GO:0043169	cation binding	3	18
GO:0050997	quaternary ammonium group binding	2	18
GO:0097159	organic cyclic compound binding	2	18
GO:1901363	heterocyclic compound binding	2	18
GO:1901681	sulfur compound binding	2	18

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	448	452	PF00656	0.574
CLV_C14_Caspase3-7	626	630	PF00656	0.515
CLV_NRD_NRD_1	182	184	PF00675	0.474
CLV_NRD_NRD_1	220	222	PF00675	0.509
CLV_NRD_NRD_1	3	5	PF00675	0.599
CLV_NRD_NRD_1	324	326	PF00675	0.298
CLV_NRD_NRD_1	479	481	PF00675	0.324
CLV_NRD_NRD_1	501	503	PF00675	0.269
CLV_NRD_NRD_1	620	622	PF00675	0.481
CLV_NRD_NRD_1	805	807	PF00675	0.390
CLV_NRD_NRD_1	825	827	PF00675	0.273
CLV_NRD_NRD_1	876	878	PF00675	0.305
CLV_PCSK_FUR_1	803	807	PF00082	0.374
CLV_PCSK_KEX2_1	182	184	PF00082	0.411
CLV_PCSK_KEX2_1	3	5	PF00082	0.599
CLV_PCSK_KEX2_1	324	326	PF00082	0.378
CLV_PCSK_KEX2_1	479	481	PF00082	0.321
CLV_PCSK_KEX2_1	501	503	PF00082	0.345
CLV_PCSK_KEX2_1	805	807	PF00082	0.360
CLV_PCSK_KEX2_1	825	827	PF00082	0.273
CLV_PCSK_PC1ET2_1	324	326	PF00082	0.378
CLV_PCSK_SKI1_1	150	154	PF00082	0.353
CLV_PCSK_SKI1_1	241	245	PF00082	0.294
CLV_PCSK_SKI1_1	297	301	PF00082	0.309
CLV_PCSK_SKI1_1	3	7	PF00082	0.565
CLV_PCSK_SKI1_1	326	330	PF00082	0.298
CLV_PCSK_SKI1_1	455	459	PF00082	0.322
CLV_PCSK_SKI1_1	717	721	PF00082	0.374
CLV_PCSK_SKI1_1	878	882	PF00082	0.268
DEG_APCC_DBOX_1	2	10	PF00400	0.623
DEG_APCC_DBOX_1	281	289	PF00400	0.516
DOC_CKS1_1	814	819	PF01111	0.506
DOC_CYCLIN_RxL_1	773	784	PF00134	0.473
DOC_CYCLIN_yCln2_LP_2	256	262	PF00134	0.498
DOC_MAPK_gen_1	324	330	PF00069	0.536
DOC_MAPK_gen_1	501	509	PF00069	0.436
DOC_MAPK_gen_1	94	102	PF00069	0.425
DOC_MAPK_MEF2A_6	146	153	PF00069	0.572
DOC_MAPK_MEF2A_6	830	839	PF00069	0.511
DOC_MAPK_NFAT4_5	146	154	PF00069	0.294
DOC_PIKK_1	39	47	PF02985	0.605
DOC_PP1_RVXF_1	148	154	PF00149	0.537
DOC_PP1_RVXF_1	875	882	PF00149	0.473
DOC_PP1_RVXF_1	99	105	PF00149	0.462
DOC_PP2B_LxvP_1	756	759	PF13499	0.484
DOC_PP2B_LxvP_1	845	848	PF13499	0.576
DOC_PP4_FxxP_1	491	494	PF00568	0.473
DOC_PP4_FxxP_1	82	85	PF00568	0.543
DOC_PP4_FxxP_1	832	835	PF00568	0.516
DOC_USP7_MATH_1	342	346	PF00917	0.473
DOC_USP7_MATH_1	422	426	PF00917	0.516
DOC_USP7_MATH_1	68	72	PF00917	0.533
DOC_USP7_MATH_1	767	771	PF00917	0.506
DOC_USP7_MATH_1	77	81	PF00917	0.538
DOC_USP7_MATH_1	857	861	PF00917	0.496
DOC_USP7_MATH_1	880	884	PF00917	0.494
DOC_USP7_MATH_1	983	987	PF00917	0.518
DOC_USP7_UBL2_3	146	150	PF12436	0.298
DOC_USP7_UBL2_3	222	226	PF12436	0.403
DOC_USP7_UBL2_3	241	245	PF12436	0.622
DOC_USP7_UBL2_3	605	609	PF12436	0.561
DOC_USP7_UBL2_3	674	678	PF12436	0.574
DOC_WW_Pin1_4	683	688	PF00397	0.539
DOC_WW_Pin1_4	813	818	PF00397	0.506
DOC_WW_Pin1_4	898	903	PF00397	0.567
DOC_WW_Pin1_4	981	986	PF00397	0.471
LIG_14-3-3_CanoR_1	101	105	PF00244	0.499
LIG_14-3-3_CanoR_1	13	20	PF00244	0.630
LIG_14-3-3_CanoR_1	426	434	PF00244	0.543
LIG_14-3-3_CanoR_1	542	552	PF00244	0.664
LIG_14-3-3_CanoR_1	660	670	PF00244	0.464
LIG_14-3-3_CanoR_1	717	722	PF00244	0.418
LIG_14-3-3_CanoR_1	959	964	PF00244	0.536
LIG_14-3-3_CanoR_1	979	985	PF00244	0.480
LIG_Actin_WH2_1	284	299	PF00022	0.574
LIG_Actin_WH2_2	281	299	PF00022	0.574
LIG_Actin_WH2_2	581	596	PF00022	0.491
LIG_ActinCP_TwfCPI_2	82	89	PF01115	0.647
LIG_APCC_ABBA_1	376	381	PF00400	0.516
LIG_BRCT_BRCA1_1	194	198	PF00533	0.444
LIG_Clathr_ClatBox_1	335	339	PF01394	0.404
LIG_Clathr_ClatBox_1	910	914	PF01394	0.527
LIG_EH1_1	41	49	PF00400	0.479
LIG_FHA_1	363	369	PF00498	0.518
LIG_FHA_1	405	411	PF00498	0.501
LIG_FHA_1	509	515	PF00498	0.609
LIG_FHA_1	714	720	PF00498	0.606
LIG_FHA_1	899	905	PF00498	0.567
LIG_FHA_1	936	942	PF00498	0.540
LIG_FHA_2	171	177	PF00498	0.404
LIG_FHA_2	511	517	PF00498	0.521
LIG_FHA_2	519	525	PF00498	0.547
LIG_FHA_2	528	534	PF00498	0.554
LIG_FHA_2	561	567	PF00498	0.648
LIG_FHA_2	584	590	PF00498	0.485
LIG_FHA_2	652	658	PF00498	0.578
LIG_FHA_2	718	724	PF00498	0.574
LIG_GBD_Chelix_1	288	296	PF00786	0.374
LIG_IBAR_NPY_1	30	32	PF08397	0.661
LIG_LIR_Apic_2	490	494	PF02991	0.484
LIG_LIR_Apic_2	80	85	PF02991	0.535
LIG_LIR_Apic_2	831	835	PF02991	0.540
LIG_LIR_Gen_1	108	117	PF02991	0.494
LIG_LIR_Gen_1	235	243	PF02991	0.501
LIG_LIR_Gen_1	389	399	PF02991	0.516
LIG_LIR_Gen_1	530	540	PF02991	0.440
LIG_LIR_Gen_1	546	556	PF02991	0.378
LIG_LIR_Gen_1	566	577	PF02991	0.720
LIG_LIR_Gen_1	775	783	PF02991	0.516
LIG_LIR_Gen_1	937	947	PF02991	0.496
LIG_LIR_Nem_3	108	112	PF02991	0.448
LIG_LIR_Nem_3	195	201	PF02991	0.383
LIG_LIR_Nem_3	235	240	PF02991	0.501
LIG_LIR_Nem_3	393	399	PF02991	0.540
LIG_LIR_Nem_3	530	535	PF02991	0.522
LIG_LIR_Nem_3	546	552	PF02991	0.374
LIG_LIR_Nem_3	566	572	PF02991	0.721
LIG_LIR_Nem_3	59	65	PF02991	0.490
LIG_LIR_Nem_3	723	729	PF02991	0.521
LIG_LIR_Nem_3	775	780	PF02991	0.473
LIG_LIR_Nem_3	789	794	PF02991	0.473
LIG_LIR_Nem_3	860	865	PF02991	0.505
LIG_LIR_Nem_3	937	943	PF02991	0.488
LIG_LIR_Nem_3	986	992	PF02991	0.498
LIG_MLH1_MIPbox_1	195	199	PF16413	0.483
LIG_MYND_3	63	67	PF01753	0.513
LIG_PAM2_1	812	824	PF00658	0.574
LIG_PCNA_PIPBox_1	960	969	PF02747	0.494
LIG_Pex14_1	722	726	PF04695	0.506
LIG_Pex14_1	809	813	PF04695	0.506
LIG_Pex14_2	463	467	PF04695	0.464
LIG_Rb_LxCxE_1	738	757	PF01857	0.516
LIG_REV1ctd_RIR_1	196	206	PF16727	0.397
LIG_REV1ctd_RIR_1	837	846	PF16727	0.507
LIG_SH2_CRK	185	189	PF00017	0.484
LIG_SH2_CRK	32	36	PF00017	0.654
LIG_SH2_CRK	569	573	PF00017	0.678
LIG_SH2_CRK	989	993	PF00017	0.473
LIG_SH2_NCK_1	569	573	PF00017	0.595
LIG_SH2_STAP1	161	165	PF00017	0.456
LIG_SH2_STAP1	32	36	PF00017	0.572
LIG_SH2_STAP1	364	368	PF00017	0.573
LIG_SH2_STAP1	510	514	PF00017	0.527
LIG_SH2_STAP1	569	573	PF00017	0.678
LIG_SH2_STAT5	185	188	PF00017	0.403
LIG_SH2_STAT5	20	23	PF00017	0.599
LIG_SH2_STAT5	364	367	PF00017	0.551
LIG_SH2_STAT5	43	46	PF00017	0.458
LIG_SH2_STAT5	430	433	PF00017	0.498
LIG_SH2_STAT5	510	513	PF00017	0.615
LIG_SH2_STAT5	679	682	PF00017	0.540
LIG_SH2_STAT5	820	823	PF00017	0.516
LIG_SH3_3	552	558	PF00018	0.652
LIG_SH3_3	574	580	PF00018	0.657
LIG_SH3_3	808	814	PF00018	0.503
LIG_Sin3_3	862	869	PF02671	0.574
LIG_SUMO_SIM_anti_2	337	342	PF11976	0.498
LIG_SUMO_SIM_anti_2	906	912	PF11976	0.514
LIG_SUMO_SIM_par_1	334	339	PF11976	0.494
LIG_SUMO_SIM_par_1	505	511	PF11976	0.496
LIG_SUMO_SIM_par_1	690	695	PF11976	0.518
LIG_SUMO_SIM_par_1	906	912	PF11976	0.574
LIG_TRAF2_1	138	141	PF00917	0.429
LIG_TRAF2_1	173	176	PF00917	0.277
LIG_TRAF2_1	217	220	PF00917	0.549
LIG_TRAF2_1	521	524	PF00917	0.546
LIG_TYR_ITIM	223	228	PF00017	0.376
LIG_TYR_ITIM	567	572	PF00017	0.519
LIG_TYR_ITIM	677	682	PF00017	0.540
LIG_TYR_ITSM	985	992	PF00017	0.473
LIG_UBA3_1	963	970	PF00899	0.540
LIG_WRC_WIRS_1	79	84	PF05994	0.554
MOD_CK1_1	167	173	PF00069	0.494
MOD_CK1_1	295	301	PF00069	0.404
MOD_CK1_1	425	431	PF00069	0.508
MOD_CK1_1	560	566	PF00069	0.674
MOD_CK1_1	695	701	PF00069	0.508
MOD_CK1_1	781	787	PF00069	0.521
MOD_CK1_1	80	86	PF00069	0.603
MOD_CK1_1	978	984	PF00069	0.494
MOD_CK2_1	170	176	PF00069	0.368
MOD_CK2_1	342	348	PF00069	0.512
MOD_CK2_1	386	392	PF00069	0.504
MOD_CK2_1	510	516	PF00069	0.512
MOD_CK2_1	518	524	PF00069	0.526
MOD_CK2_1	583	589	PF00069	0.519
MOD_CK2_1	695	701	PF00069	0.498
MOD_CK2_1	717	723	PF00069	0.555
MOD_CK2_1	739	745	PF00069	0.527
MOD_CK2_1	87	93	PF00069	0.588
MOD_Cter_Amidation	322	325	PF01082	0.294
MOD_GlcNHglycan	122	125	PF01048	0.675
MOD_GlcNHglycan	14	17	PF01048	0.664
MOD_GlcNHglycan	166	169	PF01048	0.535
MOD_GlcNHglycan	195	198	PF01048	0.446
MOD_GlcNHglycan	273	276	PF01048	0.391
MOD_GlcNHglycan	314	317	PF01048	0.316
MOD_GlcNHglycan	427	430	PF01048	0.387
MOD_GlcNHglycan	54	57	PF01048	0.624
MOD_GlcNHglycan	563	566	PF01048	0.612
MOD_GlcNHglycan	6	9	PF01048	0.776
MOD_GlcNHglycan	762	765	PF01048	0.318
MOD_GlcNHglycan	770	773	PF01048	0.318
MOD_GlcNHglycan	882	885	PF01048	0.298
MOD_GlcNHglycan	981	984	PF01048	0.372
MOD_GSK3_1	153	160	PF00069	0.480
MOD_GSK3_1	164	171	PF00069	0.536
MOD_GSK3_1	18	25	PF00069	0.582
MOD_GSK3_1	386	393	PF00069	0.543
MOD_GSK3_1	425	432	PF00069	0.506
MOD_GSK3_1	527	534	PF00069	0.592
MOD_GSK3_1	557	564	PF00069	0.628
MOD_GSK3_1	668	675	PF00069	0.522
MOD_GSK3_1	681	688	PF00069	0.522
MOD_GSK3_1	690	697	PF00069	0.471
MOD_GSK3_1	713	720	PF00069	0.494
MOD_GSK3_1	809	816	PF00069	0.589
MOD_GSK3_1	975	982	PF00069	0.527
MOD_GSK3_1	984	991	PF00069	0.520
MOD_N-GLC_1	153	158	PF02516	0.470
MOD_N-GLC_1	18	23	PF02516	0.551
MOD_N-GLC_1	483	488	PF02516	0.322
MOD_N-GLC_1	543	548	PF02516	0.321
MOD_N-GLC_1	561	566	PF02516	0.652
MOD_N-GLC_1	695	700	PF02516	0.321
MOD_N-GLC_1	848	853	PF02516	0.447
MOD_NEK2_1	100	105	PF00069	0.417
MOD_NEK2_1	153	158	PF00069	0.411
MOD_NEK2_1	193	198	PF00069	0.463
MOD_NEK2_1	265	270	PF00069	0.424
MOD_NEK2_1	292	297	PF00069	0.540
MOD_NEK2_1	543	548	PF00069	0.463
MOD_NEK2_1	713	718	PF00069	0.578
MOD_NEK2_1	754	759	PF00069	0.479
MOD_NEK2_2	386	391	PF00069	0.516
MOD_NEK2_2	988	993	PF00069	0.496
MOD_PIKK_1	489	495	PF00454	0.506
MOD_PIKK_1	543	549	PF00454	0.444
MOD_PIKK_1	661	667	PF00454	0.488
MOD_PIKK_1	685	691	PF00454	0.565
MOD_PKA_1	622	628	PF00069	0.553
MOD_PKA_2	100	106	PF00069	0.479
MOD_PKA_2	12	18	PF00069	0.744
MOD_PKA_2	425	431	PF00069	0.506
MOD_PKA_2	651	657	PF00069	0.510
MOD_PKA_2	659	665	PF00069	0.500
MOD_PKA_2	978	984	PF00069	0.499
MOD_PKB_1	957	965	PF00069	0.540
MOD_Plk_1	153	159	PF00069	0.403
MOD_Plk_1	161	167	PF00069	0.424
MOD_Plk_1	368	374	PF00069	0.559
MOD_Plk_1	565	571	PF00069	0.537
MOD_Plk_1	614	620	PF00069	0.572
MOD_Plk_1	695	701	PF00069	0.473
MOD_Plk_1	871	877	PF00069	0.476
MOD_Plk_2-3	87	93	PF00069	0.629
MOD_Plk_4	100	106	PF00069	0.412
MOD_Plk_4	161	167	PF00069	0.505
MOD_Plk_4	369	375	PF00069	0.576
MOD_Plk_4	510	516	PF00069	0.455
MOD_Plk_4	531	537	PF00069	0.449
MOD_Plk_4	58	64	PF00069	0.444
MOD_Plk_4	885	891	PF00069	0.484
MOD_Plk_4	959	965	PF00069	0.518
MOD_ProDKin_1	683	689	PF00069	0.539
MOD_ProDKin_1	813	819	PF00069	0.506
MOD_ProDKin_1	898	904	PF00069	0.567
MOD_ProDKin_1	981	987	PF00069	0.471
MOD_SUMO_for_1	525	528	PF00179	0.504
MOD_SUMO_rev_2	145	152	PF00179	0.295
MOD_SUMO_rev_2	218	223	PF00179	0.456
MOD_SUMO_rev_2	523	527	PF00179	0.574
MOD_SUMO_rev_2	83	91	PF00179	0.686
MOD_SUMO_rev_2	887	896	PF00179	0.494
MOD_SUMO_rev_2	991	1001	PF00179	0.523
TRG_DiLeu_BaEn_1	147	152	PF01217	0.292
TRG_DiLeu_BaEn_1	750	755	PF01217	0.574
TRG_DiLeu_BaEn_1	996	1001	PF01217	0.498
TRG_ENDOCYTIC_2	109	112	PF00928	0.458
TRG_ENDOCYTIC_2	225	228	PF00928	0.482
TRG_ENDOCYTIC_2	32	35	PF00928	0.600
TRG_ENDOCYTIC_2	391	394	PF00928	0.484
TRG_ENDOCYTIC_2	497	500	PF00928	0.467
TRG_ENDOCYTIC_2	540	543	PF00928	0.522
TRG_ENDOCYTIC_2	569	572	PF00928	0.679
TRG_ENDOCYTIC_2	679	682	PF00928	0.527
TRG_ENDOCYTIC_2	820	823	PF00928	0.506
TRG_ENDOCYTIC_2	989	992	PF00928	0.473
TRG_ER_diArg_1	181	183	PF00400	0.437
TRG_ER_diArg_1	2	4	PF00400	0.605
TRG_ER_diArg_1	282	285	PF00400	0.506
TRG_ER_diArg_1	478	480	PF00400	0.486
TRG_ER_diArg_1	500	502	PF00400	0.540
TRG_ER_diArg_1	69	72	PF00400	0.369
TRG_ER_diArg_1	802	805	PF00400	0.557
TRG_ER_diArg_1	824	826	PF00400	0.506
TRG_ER_diArg_1	956	959	PF00400	0.473
TRG_NES_CRM1_1	637	647	PF08389	0.540
TRG_NLS_MonoExtC_3	620	626	PF00514	0.449
TRG_Pf-PMV_PEXEL_1	135	140	PF00026	0.565
TRG_Pf-PMV_PEXEL_1	24	28	PF00026	0.612
TRG_Pf-PMV_PEXEL_1	512	516	PF00026	0.390
TRG_Pf-PMV_PEXEL_1	89	93	PF00026	0.583

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HVP3	Leptomonas seymouri	78%	100%
A0A0N1HXR5	Leptomonas seymouri	38%	99%
A0A0S4JH30	Bodo saltans	39%	100%
A0A0S4JV11	Bodo saltans	51%	98%
A0A1X0P3C5	Trypanosomatidae	38%	100%
A0A1X0P407	Trypanosomatidae	62%	100%
A0A3Q8IEB5	Leishmania donovani	90%	100%
A0A3R7KVU5	Trypanosoma rangeli	36%	100%
A0A3S5IR73	Trypanosoma rangeli	58%	100%
A0A3S7XBB9	Leishmania donovani	39%	100%
A0PVU7	Mycobacterium ulcerans (strain Agy99)	35%	81%
A0R2B1	Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)	36%	82%
A1KI36	Mycobacterium bovis (strain BCG / Pasteur 1173P2)	35%	82%
A1TDK2	Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 / PYR-1)	36%	81%
A1UK81	Mycobacterium sp. (strain KMS)	35%	79%
A2ATU0	Mus musculus	35%	100%
A3Q3N5	Mycobacterium sp. (strain JLS)	35%	80%
A4HPL4	Leishmania braziliensis	38%	100%
A4I2P6	Leishmania infantum	90%	100%
A4ID50	Leishmania infantum	39%	100%
A5ISU5	Staphylococcus aureus (strain JH9)	34%	100%
A5U1U6	Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)	35%	82%
A5VSQ0	Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)	37%	100%
A6QGW6	Staphylococcus aureus (strain Newman)	34%	100%
A6U1N4	Staphylococcus aureus (strain JH1)	34%	100%
A6WXF0	Brucella anthropi (strain ATCC 49188 / DSM 6882 / CCUG 24695 / JCM 21032 / LMG 3331 / NBRC 15819 / NCTC 12168 / Alc 37)	37%	100%
A7GMD4	Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)	34%	100%
A7X295	Staphylococcus aureus (strain Mu3 / ATCC 700698)	34%	100%
A7Z5J9	Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42)	35%	100%
A8FE66	Bacillus pumilus (strain SAFR-032)	34%	100%
A8Z3Z0	Staphylococcus aureus (strain USA300 / TCH1516)	34%	100%
A9M8Q9	Brucella canis (strain ATCC 23365 / NCTC 10854)	37%	100%
A9VJX9	Bacillus mycoides (strain KBAB4)	35%	100%
B0CIS7	Brucella suis (strain ATCC 23445 / NCTC 10510)	37%	100%
B2S877	Brucella abortus (strain S19)	37%	100%
B7HH19	Bacillus cereus (strain B4264)	35%	100%
B7I0H2	Bacillus cereus (strain AH187)	35%	100%
B7IM94	Bacillus cereus (strain G9842)	35%	100%
B7JEU9	Bacillus cereus (strain AH820)	35%	100%
B9IU58	Bacillus cereus (strain Q1)	35%	100%
C0RFG8	Brucella melitensis biotype 2 (strain ATCC 23457)	37%	100%
C1ELG5	Bacillus cereus (strain 03BB102)	36%	100%
C3LAU3	Bacillus anthracis (strain CDC 684 / NRRL 3495)	35%	100%
C3P487	Bacillus anthracis (strain A0248)	35%	100%
C4L3W2	Exiguobacterium sp. (strain ATCC BAA-1283 / AT1b)	34%	100%
C5D802	Geobacillus sp. (strain WCH70)	35%	100%
D0A5T7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	55%	100%
D0A8K0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
D3ZQD3	Rattus norvegicus	37%	100%
E9AD65	Leishmania major	89%	100%
E9ATC6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	39%	100%
E9AYZ0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
O61199	Caenorhabditis elegans	36%	98%
O74378	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	100%
P0AFG3	Escherichia coli (strain K12)	35%	100%
P0AFG4	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	35%	100%
P0AFG5	Escherichia coli O157:H7	35%	100%
P0C601	Staphylococcus aureus	34%	100%
P20707	Azotobacter vinelandii	36%	100%
P20967	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	99%
P23129	Bacillus subtilis (strain 168)	33%	100%
P45303	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	34%	100%
P51056	Coxiella burnetii (strain RSA 493 / Nine Mile phase I)	35%	100%
P57388	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	33%	100%
P9WIS4	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	35%	82%
P9WIS5	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	35%	82%
Q02218	Homo sapiens	36%	98%
Q148N0	Bos taurus	35%	98%
Q1B4V6	Mycobacterium sp. (strain MCS)	35%	79%
Q1RHI4	Rickettsia bellii (strain RML369-C)	35%	100%
Q23629	Caenorhabditis elegans	35%	100%
Q2FH25	Staphylococcus aureus (strain USA300)	34%	100%
Q2FYM1	Staphylococcus aureus (strain NCTC 8325 / PS 47)	34%	100%
Q2YLS2	Brucella abortus (strain 2308)	37%	100%
Q2YY05	Staphylococcus aureus (strain bovine RF122 / ET3-1)	34%	100%
Q49XM5	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)	34%	100%
Q4KLP0	Rattus norvegicus	35%	100%
Q4L6C4	Staphylococcus haemolyticus (strain JCSC1435)	34%	100%
Q4Q171	Leishmania major	39%	98%
Q4UKI8	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)	37%	100%
Q54JE4	Dictyostelium discoideum	38%	99%
Q54VG0	Dictyostelium discoideum	32%	100%
Q57AX5	Brucella abortus biovar 1 (strain 9-941)	37%	100%
Q59106	Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)	37%	100%
Q5HG06	Staphylococcus aureus (strain COL)	34%	100%
Q5HPC6	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	34%	100%
Q5L172	Geobacillus kaustophilus (strain HTA426)	34%	100%
Q5PRA2	Danio rerio	35%	100%
Q5R7H0	Pongo abelii	34%	100%
Q5R9L8	Pongo abelii	38%	100%
Q5RCB8	Pongo abelii	36%	98%
Q5WG56	Alkalihalobacillus clausii (strain KSM-K16)	34%	100%
Q5XI78	Rattus norvegicus	36%	98%
Q60597	Mus musculus	35%	98%
Q60HE2	Macaca fascicularis	36%	98%
Q623T0	Caenorhabditis briggsae	38%	98%
Q63EB1	Bacillus cereus (strain ZK / E33L)	36%	100%
Q65IH4	Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46)	34%	100%
Q68EW0	Xenopus laevis	36%	99%
Q68XI7	Rickettsia typhi (strain ATCC VR-144 / Wilmington)	36%	100%
Q6G9E8	Staphylococcus aureus (strain MSSA476)	34%	100%
Q6GGZ5	Staphylococcus aureus (strain MRSA252)	34%	100%
Q6HLS8	Bacillus thuringiensis subsp. konkukian (strain 97-27)	35%	100%
Q6P286	Xenopus laevis	34%	100%
Q6P6Z8	Xenopus laevis	36%	99%
Q72PJ7	Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)	37%	100%
Q73BN8	Bacillus cereus (strain ATCC 10987 / NRS 248)	35%	100%
Q73WX4	Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)	35%	81%
Q7U0A6	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	35%	82%
Q81GF2	Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)	35%	100%
Q81TK1	Bacillus anthracis	35%	100%
Q89AJ7	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	34%	100%
Q8CP83	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	34%	100%
Q8CUL8	Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)	34%	100%
Q8F6S7	Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)	37%	100%
Q8FYF7	Brucella suis biovar 1 (strain 1330)	37%	100%
Q8K9N3	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	35%	100%
Q8NRC3	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)	38%	82%
Q8NWR6	Staphylococcus aureus (strain MW2)	34%	100%
Q8YJE4	Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)	37%	100%
Q92J42	Rickettsia conorii (strain ATCC VR-613 / Malish 7)	36%	100%
Q931R8	Staphylococcus aureus (strain Mu50 / ATCC 700699)	34%	100%
Q96HY7	Homo sapiens	34%	100%
Q99U74	Staphylococcus aureus (strain N315)	34%	100%
Q9CC97	Mycobacterium leprae (strain TN)	35%	81%
Q9KAT1	Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)	34%	100%
Q9ULD0	Homo sapiens	38%	100%
Q9VA02	Drosophila melanogaster	32%	100%
Q9ZDY3	Rickettsia prowazekii (strain Madrid E)	36%	100%
V5BIL1	Trypanosoma cruzi	60%	100%
V5BWU3	Trypanosoma cruzi	37%	100%