LeishMANIAdb
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Stress-response A/B barrel domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Stress-response A/B barrel domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HFJ8_LEIBR
TriTrypDb:
LbrM.27.0830 , LBRM2903_270014000
Length:
110

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 10
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 16
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 13
NetGPI no yes: 0, no: 13
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HFJ8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HFJ8

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_PCSK_SKI1_1 90 94 PF00082 0.371
DEG_Nend_Nbox_1 1 3 PF02207 0.316
DOC_MAPK_MEF2A_6 93 102 PF00069 0.382
DOC_PP2B_LxvP_1 95 98 PF13499 0.244
DOC_USP7_MATH_1 19 23 PF00917 0.286
DOC_USP7_MATH_1 64 68 PF00917 0.379
DOC_USP7_UBL2_3 8 12 PF12436 0.410
LIG_BIR_III_4 56 60 PF00653 0.182
LIG_Clathr_ClatBox_1 6 10 PF01394 0.330
LIG_FHA_1 60 66 PF00498 0.238
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P6U1 Leptomonas seymouri 66% 99%
A0A0N0P783 Leptomonas seymouri 35% 86%
A0A0S4JUQ9 Bodo saltans 39% 100%
A0A0S4JVR8 Bodo saltans 39% 75%
A0A1X0P411 Trypanosomatidae 36% 100%
A0A1X0P4A0 Trypanosomatidae 35% 98%
A0A3Q8IE23 Leishmania donovani 67% 100%
A0A422NMP7 Trypanosoma rangeli 42% 96%
D0A5S3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 40% 99%
E9AHE6 Leishmania infantum 67% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS