Belongs to a unique family or proteins highly conserved in Kinetoplastida, but not seen outside that group.
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 10 |
| NetGPI | no | yes: 0, no: 10 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0016020 | membrane | 2 | 9 |
| GO:0110165 | cellular anatomical entity | 1 | 9 |
| GO:0005739 | mitochondrion | 5 | 1 |
| GO:0043226 | organelle | 2 | 1 |
| GO:0043227 | membrane-bounded organelle | 3 | 1 |
| GO:0043229 | intracellular organelle | 3 | 1 |
| GO:0043231 | intracellular membrane-bounded organelle | 4 | 1 |
Related structures:
AlphaFold database: A4HFJ1
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_NRD_NRD_1 | 121 | 123 | PF00675 | 0.326 |
| CLV_NRD_NRD_1 | 138 | 140 | PF00675 | 0.341 |
| CLV_NRD_NRD_1 | 17 | 19 | PF00675 | 0.348 |
| CLV_NRD_NRD_1 | 61 | 63 | PF00675 | 0.630 |
| CLV_PCSK_KEX2_1 | 120 | 122 | PF00082 | 0.337 |
| CLV_PCSK_KEX2_1 | 138 | 140 | PF00082 | 0.341 |
| CLV_PCSK_KEX2_1 | 61 | 63 | PF00082 | 0.576 |
| CLV_PCSK_SKI1_1 | 99 | 103 | PF00082 | 0.417 |
| DEG_APCC_DBOX_1 | 98 | 106 | PF00400 | 0.440 |
| DEG_Nend_UBRbox_1 | 1 | 4 | PF02207 | 0.606 |
| DOC_MAPK_MEF2A_6 | 145 | 154 | PF00069 | 0.594 |
| DOC_MAPK_RevD_3 | 5 | 19 | PF00069 | 0.506 |
| DOC_PP4_FxxP_1 | 64 | 67 | PF00568 | 0.429 |
| DOC_WW_Pin1_4 | 90 | 95 | PF00397 | 0.366 |
| LIG_14-3-3_CanoR_1 | 18 | 28 | PF00244 | 0.540 |
| LIG_deltaCOP1_diTrp_1 | 11 | 20 | PF00928 | 0.538 |
| LIG_eIF4E_1 | 97 | 103 | PF01652 | 0.434 |
| LIG_FHA_1 | 105 | 111 | PF00498 | 0.378 |
| LIG_FHA_2 | 20 | 26 | PF00498 | 0.534 |
| LIG_GBD_Chelix_1 | 150 | 158 | PF00786 | 0.428 |
| LIG_LIR_Gen_1 | 147 | 156 | PF02991 | 0.632 |
| LIG_LIR_Nem_3 | 107 | 111 | PF02991 | 0.335 |
| LIG_LIR_Nem_3 | 147 | 152 | PF02991 | 0.600 |
| LIG_PDZ_Class_2 | 162 | 167 | PF00595 | 0.673 |
| LIG_SH2_CRK | 97 | 101 | PF00017 | 0.378 |
| LIG_SH2_GRB2like | 126 | 129 | PF00017 | 0.471 |
| LIG_SH2_STAT3 | 126 | 129 | PF00017 | 0.541 |
| LIG_SH2_STAT3 | 92 | 95 | PF00017 | 0.360 |
| LIG_SH2_STAT5 | 126 | 129 | PF00017 | 0.541 |
| LIG_SH2_STAT5 | 149 | 152 | PF00017 | 0.628 |
| LIG_SH2_STAT5 | 53 | 56 | PF00017 | 0.354 |
| LIG_SH2_STAT5 | 9 | 12 | PF00017 | 0.539 |
| LIG_SH2_STAT5 | 92 | 95 | PF00017 | 0.360 |
| LIG_SH3_3 | 100 | 106 | PF00018 | 0.407 |
| LIG_WRC_WIRS_1 | 105 | 110 | PF05994 | 0.411 |
| MOD_GlcNHglycan | 142 | 145 | PF01048 | 0.400 |
| MOD_GlcNHglycan | 54 | 57 | PF01048 | 0.299 |
| MOD_GSK3_1 | 154 | 161 | PF00069 | 0.534 |
| MOD_GSK3_1 | 52 | 59 | PF00069 | 0.311 |
| MOD_NEK2_1 | 140 | 145 | PF00069 | 0.500 |
| MOD_NEK2_1 | 52 | 57 | PF00069 | 0.301 |
| MOD_NEK2_2 | 56 | 61 | PF00069 | 0.365 |
| MOD_PIKK_1 | 158 | 164 | PF00454 | 0.609 |
| MOD_Plk_1 | 3 | 9 | PF00069 | 0.579 |
| MOD_Plk_4 | 104 | 110 | PF00069 | 0.319 |
| MOD_Plk_4 | 128 | 134 | PF00069 | 0.550 |
| MOD_Plk_4 | 46 | 52 | PF00069 | 0.284 |
| MOD_ProDKin_1 | 90 | 96 | PF00069 | 0.367 |
| MOD_SUMO_for_1 | 1 | 4 | PF00179 | 0.606 |
| MOD_SUMO_rev_2 | 147 | 157 | PF00179 | 0.705 |
| MOD_SUMO_rev_2 | 71 | 78 | PF00179 | 0.488 |
| TRG_ENDOCYTIC_2 | 149 | 152 | PF00928 | 0.627 |
| TRG_ENDOCYTIC_2 | 97 | 100 | PF00928 | 0.353 |
| TRG_ER_diArg_1 | 120 | 122 | PF00400 | 0.538 |
| TRG_ER_diArg_1 | 138 | 140 | PF00400 | 0.543 |
| TRG_ER_diArg_1 | 60 | 62 | PF00400 | 0.409 |
| TRG_Pf-PMV_PEXEL_1 | 138 | 142 | PF00026 | 0.434 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P780 | Leptomonas seymouri | 79% | 100% |
| A0A0S4JRI7 | Bodo saltans | 61% | 99% |
| A0A1X0P491 | Trypanosomatidae | 62% | 99% |
| A0A3Q8IE57 | Leishmania donovani | 92% | 100% |
| A0A422NMQ9 | Trypanosoma rangeli | 67% | 99% |
| D0A5R7 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 63% | 99% |
| E9AD42 | Leishmania major | 92% | 100% |
| E9AHD5 | Leishmania infantum | 92% | 100% |
| E9AYW6 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 90% | 100% |