Mitochondrial SSU ribosomal protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Mitochondrial SSU ribosomal protein, putative

Species:

Leishmania braziliensis

UniProt:

A4HFI9_LEIBR

TriTrypDb:

LbrM.27.0740 , LBRM2903_270012500

Length:

890

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	2
GO:0005840	ribosome	5	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1

Expansion

Sequence features

A4HFI9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HFI9

PDB structure(s): 7ane_u

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	771	775	PF00656	0.315
CLV_NRD_NRD_1	194	196	PF00675	0.385
CLV_NRD_NRD_1	205	207	PF00675	0.373
CLV_NRD_NRD_1	247	249	PF00675	0.424
CLV_NRD_NRD_1	31	33	PF00675	0.683
CLV_NRD_NRD_1	379	381	PF00675	0.395
CLV_NRD_NRD_1	545	547	PF00675	0.480
CLV_NRD_NRD_1	552	554	PF00675	0.440
CLV_NRD_NRD_1	601	603	PF00675	0.457
CLV_NRD_NRD_1	672	674	PF00675	0.424
CLV_NRD_NRD_1	747	749	PF00675	0.335
CLV_NRD_NRD_1	790	792	PF00675	0.368
CLV_NRD_NRD_1	808	810	PF00675	0.357
CLV_NRD_NRD_1	861	863	PF00675	0.534
CLV_PCSK_FUR_1	669	673	PF00082	0.464
CLV_PCSK_KEX2_1	205	207	PF00082	0.488
CLV_PCSK_KEX2_1	247	249	PF00082	0.403
CLV_PCSK_KEX2_1	31	33	PF00082	0.683
CLV_PCSK_KEX2_1	378	380	PF00082	0.347
CLV_PCSK_KEX2_1	528	530	PF00082	0.514
CLV_PCSK_KEX2_1	545	547	PF00082	0.403
CLV_PCSK_KEX2_1	601	603	PF00082	0.422
CLV_PCSK_KEX2_1	671	673	PF00082	0.418
CLV_PCSK_KEX2_1	702	704	PF00082	0.394
CLV_PCSK_KEX2_1	731	733	PF00082	0.371
CLV_PCSK_KEX2_1	747	749	PF00082	0.270
CLV_PCSK_KEX2_1	808	810	PF00082	0.470
CLV_PCSK_KEX2_1	842	844	PF00082	0.502
CLV_PCSK_PC1ET2_1	378	380	PF00082	0.347
CLV_PCSK_PC1ET2_1	528	530	PF00082	0.550
CLV_PCSK_PC1ET2_1	702	704	PF00082	0.394
CLV_PCSK_PC1ET2_1	731	733	PF00082	0.382
CLV_PCSK_PC1ET2_1	842	844	PF00082	0.475
CLV_PCSK_PC7_1	838	844	PF00082	0.447
CLV_PCSK_SKI1_1	154	158	PF00082	0.397
CLV_PCSK_SKI1_1	212	216	PF00082	0.397
CLV_PCSK_SKI1_1	217	221	PF00082	0.406
CLV_PCSK_SKI1_1	249	253	PF00082	0.414
CLV_PCSK_SKI1_1	254	258	PF00082	0.406
CLV_PCSK_SKI1_1	280	284	PF00082	0.386
CLV_PCSK_SKI1_1	380	384	PF00082	0.427
CLV_PCSK_SKI1_1	387	391	PF00082	0.442
CLV_PCSK_SKI1_1	398	402	PF00082	0.425
CLV_PCSK_SKI1_1	425	429	PF00082	0.588
CLV_PCSK_SKI1_1	446	450	PF00082	0.401
CLV_PCSK_SKI1_1	501	505	PF00082	0.399
CLV_PCSK_SKI1_1	515	519	PF00082	0.400
CLV_PCSK_SKI1_1	524	528	PF00082	0.501
CLV_PCSK_SKI1_1	838	842	PF00082	0.400
CLV_PCSK_SKI1_1	843	847	PF00082	0.405
CLV_Separin_Metazoa	244	248	PF03568	0.436
DEG_APCC_DBOX_1	670	678	PF00400	0.462
DEG_Nend_Nbox_1	1	3	PF02207	0.645
DEG_SCF_FBW7_1	318	324	PF00400	0.480
DOC_CKS1_1	318	323	PF01111	0.485
DOC_CKS1_1	846	851	PF01111	0.406
DOC_CYCLIN_RxL_1	384	392	PF00134	0.492
DOC_CYCLIN_RxL_1	495	506	PF00134	0.507
DOC_CYCLIN_RxL_1	524	533	PF00134	0.459
DOC_CYCLIN_RxL_1	838	848	PF00134	0.418
DOC_CYCLIN_yClb1_LxF_4	267	272	PF00134	0.277
DOC_CYCLIN_yCln2_LP_2	504	510	PF00134	0.496
DOC_MAPK_gen_1	528	536	PF00069	0.317
DOC_MAPK_gen_1	838	847	PF00069	0.421
DOC_MAPK_MEF2A_6	236	245	PF00069	0.391
DOC_MAPK_MEF2A_6	298	307	PF00069	0.294
DOC_MAPK_MEF2A_6	797	805	PF00069	0.540
DOC_PP1_RVXF_1	189	195	PF00149	0.319
DOC_PP1_RVXF_1	267	273	PF00149	0.454
DOC_PP1_RVXF_1	278	284	PF00149	0.384
DOC_PP4_FxxP_1	684	687	PF00568	0.410
DOC_PP4_FxxP_1	846	849	PF00568	0.381
DOC_USP7_MATH_1	228	232	PF00917	0.558
DOC_USP7_MATH_1	402	406	PF00917	0.545
DOC_USP7_MATH_1	462	466	PF00917	0.563
DOC_USP7_MATH_1	580	584	PF00917	0.478
DOC_USP7_MATH_1	632	636	PF00917	0.648
DOC_USP7_MATH_1	637	641	PF00917	0.634
DOC_USP7_UBL2_3	524	528	PF12436	0.524
DOC_WW_Pin1_4	157	162	PF00397	0.460
DOC_WW_Pin1_4	231	236	PF00397	0.535
DOC_WW_Pin1_4	26	31	PF00397	0.688
DOC_WW_Pin1_4	296	301	PF00397	0.470
DOC_WW_Pin1_4	317	322	PF00397	0.520
DOC_WW_Pin1_4	371	376	PF00397	0.444
DOC_WW_Pin1_4	845	850	PF00397	0.414
LIG_14-3-3_CanoR_1	111	120	PF00244	0.482
LIG_14-3-3_CanoR_1	217	226	PF00244	0.337
LIG_14-3-3_CanoR_1	24	30	PF00244	0.586
LIG_14-3-3_CanoR_1	248	258	PF00244	0.311
LIG_14-3-3_CanoR_1	379	389	PF00244	0.273
LIG_14-3-3_CanoR_1	529	536	PF00244	0.414
LIG_14-3-3_CanoR_1	654	658	PF00244	0.351
LIG_APCC_ABBA_1	144	149	PF00400	0.466
LIG_APCC_ABBAyCdc20_2	143	149	PF00400	0.463
LIG_BIR_III_2	155	159	PF00653	0.495
LIG_BIR_III_4	734	738	PF00653	0.424
LIG_BIR_III_4	869	873	PF00653	0.559
LIG_BRCT_BRCA1_1	206	210	PF00533	0.451
LIG_BRCT_BRCA1_1	464	468	PF00533	0.433
LIG_BRCT_BRCA1_2	206	212	PF00533	0.447
LIG_deltaCOP1_diTrp_1	276	283	PF00928	0.322
LIG_deltaCOP1_diTrp_1	491	496	PF00928	0.420
LIG_deltaCOP1_diTrp_1	705	709	PF00928	0.375
LIG_EH_1	737	741	PF12763	0.483
LIG_FHA_1	12	18	PF00498	0.682
LIG_FHA_1	322	328	PF00498	0.360
LIG_FHA_1	381	387	PF00498	0.374
LIG_FHA_1	440	446	PF00498	0.607
LIG_FHA_1	525	531	PF00498	0.624
LIG_FHA_1	55	61	PF00498	0.593
LIG_FHA_1	571	577	PF00498	0.369
LIG_FHA_2	350	356	PF00498	0.461
LIG_FHA_2	419	425	PF00498	0.336
LIG_FHA_2	563	569	PF00498	0.445
LIG_FHA_2	846	852	PF00498	0.401
LIG_LIR_Apic_2	682	687	PF02991	0.513
LIG_LIR_Apic_2	734	739	PF02991	0.505
LIG_LIR_Apic_2	844	849	PF02991	0.394
LIG_LIR_Gen_1	198	209	PF02991	0.559
LIG_LIR_Gen_1	367	377	PF02991	0.508
LIG_LIR_Gen_1	565	575	PF02991	0.404
LIG_LIR_Gen_1	649	659	PF02991	0.487
LIG_LIR_Gen_1	694	704	PF02991	0.408
LIG_LIR_Gen_1	816	826	PF02991	0.436
LIG_LIR_Gen_1	851	861	PF02991	0.449
LIG_LIR_Nem_3	198	204	PF02991	0.374
LIG_LIR_Nem_3	276	282	PF02991	0.333
LIG_LIR_Nem_3	367	373	PF02991	0.517
LIG_LIR_Nem_3	511	517	PF02991	0.527
LIG_LIR_Nem_3	565	570	PF02991	0.363
LIG_LIR_Nem_3	649	655	PF02991	0.479
LIG_LIR_Nem_3	694	699	PF02991	0.411
LIG_LIR_Nem_3	798	803	PF02991	0.420
LIG_LIR_Nem_3	814	820	PF02991	0.400
LIG_LIR_Nem_3	832	837	PF02991	0.294
LIG_LIR_Nem_3	851	856	PF02991	0.421
LIG_NRBOX	147	153	PF00104	0.479
LIG_NRBOX	328	334	PF00104	0.427
LIG_NRBOX	385	391	PF00104	0.481
LIG_NRBOX	609	615	PF00104	0.484
LIG_NRBOX	782	788	PF00104	0.410
LIG_Pex14_1	279	283	PF04695	0.321
LIG_Pex14_1	706	710	PF04695	0.360
LIG_PTB_Apo_2	265	272	PF02174	0.364
LIG_PTB_Apo_2	695	702	PF02174	0.384
LIG_PTB_Phospho_1	265	271	PF10480	0.370
LIG_PTB_Phospho_1	695	701	PF10480	0.384
LIG_SH2_CRK	514	518	PF00017	0.595
LIG_SH2_CRK	696	700	PF00017	0.409
LIG_SH2_CRK	736	740	PF00017	0.502
LIG_SH2_GRB2like	696	699	PF00017	0.433
LIG_SH2_NCK_1	567	571	PF00017	0.455
LIG_SH2_PTP2	652	655	PF00017	0.401
LIG_SH2_STAP1	873	877	PF00017	0.436
LIG_SH2_STAT3	657	660	PF00017	0.382
LIG_SH2_STAT3	704	707	PF00017	0.377
LIG_SH2_STAT3	769	772	PF00017	0.384
LIG_SH2_STAT5	271	274	PF00017	0.454
LIG_SH2_STAT5	330	333	PF00017	0.340
LIG_SH2_STAT5	535	538	PF00017	0.388
LIG_SH2_STAT5	644	647	PF00017	0.358
LIG_SH2_STAT5	652	655	PF00017	0.315
LIG_SH2_STAT5	657	660	PF00017	0.294
LIG_SH2_STAT5	873	876	PF00017	0.512
LIG_SH3_3	139	145	PF00018	0.420
LIG_SH3_3	155	161	PF00018	0.461
LIG_SH3_3	315	321	PF00018	0.388
LIG_SH3_3	597	603	PF00018	0.482
LIG_SH3_3	804	810	PF00018	0.433
LIG_SUMO_SIM_anti_2	13	20	PF11976	0.488
LIG_SUMO_SIM_anti_2	571	578	PF11976	0.487
LIG_SUMO_SIM_anti_2	608	615	PF11976	0.284
LIG_SUMO_SIM_par_1	237	244	PF11976	0.359
LIG_SUMO_SIM_par_1	299	304	PF11976	0.315
LIG_SUMO_SIM_par_1	330	335	PF11976	0.397
LIG_TRAF2_1	119	122	PF00917	0.501
LIG_TRAF2_1	197	200	PF00917	0.546
LIG_TRAF2_1	360	363	PF00917	0.404
LIG_TRAF2_1	583	586	PF00917	0.448
LIG_TRAF2_1	98	101	PF00917	0.560
LIG_TYR_ITSM	563	570	PF00017	0.491
LIG_WRC_WIRS_1	167	172	PF05994	0.513
MOD_CDK_SPK_2	231	236	PF00069	0.428
MOD_CDK_SPK_2	26	31	PF00069	0.545
MOD_CDK_SPxK_1	26	32	PF00069	0.644
MOD_CDK_SPxxK_3	371	378	PF00069	0.440
MOD_CK1_1	231	237	PF00069	0.599
MOD_CK1_1	296	302	PF00069	0.531
MOD_CK1_1	451	457	PF00069	0.446
MOD_CK1_1	472	478	PF00069	0.379
MOD_CK1_1	54	60	PF00069	0.565
MOD_CK1_1	635	641	PF00069	0.399
MOD_CK1_1	811	817	PF00069	0.412
MOD_CK2_1	116	122	PF00069	0.425
MOD_CK2_1	231	237	PF00069	0.474
MOD_CK2_1	332	338	PF00069	0.475
MOD_CK2_1	438	444	PF00069	0.414
MOD_CK2_1	451	457	PF00069	0.538
MOD_CK2_1	562	568	PF00069	0.452
MOD_CK2_1	580	586	PF00069	0.354
MOD_CMANNOS	706	709	PF00535	0.367
MOD_GlcNHglycan	229	233	PF01048	0.491
MOD_GlcNHglycan	404	407	PF01048	0.521
MOD_GlcNHglycan	453	456	PF01048	0.523
MOD_GlcNHglycan	471	474	PF01048	0.381
MOD_GlcNHglycan	591	594	PF01048	0.370
MOD_GlcNHglycan	625	629	PF01048	0.587
MOD_GlcNHglycan	779	782	PF01048	0.294
MOD_GlcNHglycan	810	813	PF01048	0.405
MOD_GSK3_1	112	119	PF00069	0.453
MOD_GSK3_1	292	299	PF00069	0.458
MOD_GSK3_1	317	324	PF00069	0.549
MOD_GSK3_1	332	339	PF00069	0.395
MOD_GSK3_1	444	451	PF00069	0.434
MOD_GSK3_1	468	475	PF00069	0.368
MOD_GSK3_1	502	509	PF00069	0.432
MOD_GSK3_1	62	69	PF00069	0.401
MOD_GSK3_1	620	627	PF00069	0.541
MOD_GSK3_1	770	777	PF00069	0.381
MOD_GSK3_1	841	848	PF00069	0.421
MOD_LATS_1	127	133	PF00433	0.516
MOD_LATS_1	717	723	PF00433	0.342
MOD_N-GLC_1	217	222	PF02516	0.313
MOD_N-GLC_1	371	376	PF02516	0.471
MOD_N-GLC_1	518	523	PF02516	0.510
MOD_N-GLC_1	62	67	PF02516	0.624
MOD_N-GLC_1	719	724	PF02516	0.340
MOD_N-GLC_1	774	779	PF02516	0.371
MOD_NEK2_1	166	171	PF00069	0.504
MOD_NEK2_1	19	24	PF00069	0.692
MOD_NEK2_1	204	209	PF00069	0.475
MOD_NEK2_1	282	287	PF00069	0.437
MOD_NEK2_1	293	298	PF00069	0.468
MOD_NEK2_1	332	337	PF00069	0.405
MOD_NEK2_1	448	453	PF00069	0.410
MOD_NEK2_1	468	473	PF00069	0.490
MOD_NEK2_1	596	601	PF00069	0.351
MOD_NEK2_1	76	81	PF00069	0.470
MOD_PIKK_1	679	685	PF00454	0.535
MOD_PK_1	719	725	PF00069	0.468
MOD_PKA_1	808	814	PF00069	0.414
MOD_PKA_1	841	847	PF00069	0.419
MOD_PKA_2	204	210	PF00069	0.370
MOD_PKA_2	653	659	PF00069	0.353
MOD_PKA_2	808	814	PF00069	0.458
MOD_PKA_2	861	867	PF00069	0.478
MOD_PKB_1	618	626	PF00069	0.511
MOD_Plk_1	105	111	PF00069	0.509
MOD_Plk_1	217	223	PF00069	0.381
MOD_Plk_1	228	234	PF00069	0.473
MOD_Plk_1	418	424	PF00069	0.384
MOD_Plk_1	562	568	PF00069	0.410
MOD_Plk_1	570	576	PF00069	0.366
MOD_Plk_1	605	611	PF00069	0.297
MOD_Plk_1	62	68	PF00069	0.557
MOD_Plk_1	679	685	PF00069	0.329
MOD_Plk_1	719	725	PF00069	0.337
MOD_Plk_1	774	780	PF00069	0.373
MOD_Plk_2-3	506	512	PF00069	0.421
MOD_Plk_2-3	563	569	PF00069	0.390
MOD_Plk_2-3	827	833	PF00069	0.412
MOD_Plk_4	105	111	PF00069	0.571
MOD_Plk_4	444	450	PF00069	0.409
MOD_Plk_4	605	611	PF00069	0.388
MOD_Plk_4	638	644	PF00069	0.418
MOD_Plk_4	653	659	PF00069	0.350
MOD_Plk_4	813	819	PF00069	0.445
MOD_ProDKin_1	157	163	PF00069	0.453
MOD_ProDKin_1	231	237	PF00069	0.538
MOD_ProDKin_1	26	32	PF00069	0.689
MOD_ProDKin_1	296	302	PF00069	0.456
MOD_ProDKin_1	317	323	PF00069	0.510
MOD_ProDKin_1	371	377	PF00069	0.443
MOD_ProDKin_1	845	851	PF00069	0.415
MOD_SUMO_rev_2	341	350	PF00179	0.383
MOD_SUMO_rev_2	440	448	PF00179	0.416
MOD_SUMO_rev_2	728	733	PF00179	0.473
MOD_SUMO_rev_2	798	807	PF00179	0.427
MOD_SUMO_rev_2	822	831	PF00179	0.523
MOD_SUMO_rev_2	851	859	PF00179	0.450
TRG_DiLeu_BaEn_1	444	449	PF01217	0.385
TRG_DiLeu_BaEn_2	252	258	PF01217	0.265
TRG_DiLeu_BaEn_3	260	266	PF01217	0.274
TRG_DiLeu_BaEn_4	121	127	PF01217	0.485
TRG_DiLeu_BaLyEn_6	512	517	PF01217	0.451
TRG_ENDOCYTIC_2	201	204	PF00928	0.485
TRG_ENDOCYTIC_2	330	333	PF00928	0.375
TRG_ENDOCYTIC_2	514	517	PF00928	0.589
TRG_ENDOCYTIC_2	567	570	PF00928	0.420
TRG_ENDOCYTIC_2	652	655	PF00928	0.373
TRG_ENDOCYTIC_2	696	699	PF00928	0.402
TRG_ENDOCYTIC_2	710	713	PF00928	0.316
TRG_ENDOCYTIC_2	817	820	PF00928	0.426
TRG_ER_diArg_1	189	192	PF00400	0.483
TRG_ER_diArg_1	204	206	PF00400	0.356
TRG_ER_diArg_1	246	248	PF00400	0.414
TRG_ER_diArg_1	266	269	PF00400	0.561
TRG_ER_diArg_1	30	32	PF00400	0.691
TRG_ER_diArg_1	379	381	PF00400	0.395
TRG_ER_diArg_1	600	602	PF00400	0.466
TRG_ER_diArg_1	617	620	PF00400	0.483
TRG_ER_diArg_1	669	672	PF00400	0.429
TRG_ER_diArg_1	747	750	PF00400	0.345
TRG_ER_diArg_1	807	809	PF00400	0.481
TRG_NLS_MonoExtC_3	552	558	PF00514	0.453
TRG_NLS_MonoExtN_4	375	382	PF00514	0.391
TRG_NLS_MonoExtN_4	838	845	PF00514	0.427
TRG_Pf-PMV_PEXEL_1	501	506	PF00026	0.501
TRG_Pf-PMV_PEXEL_1	750	754	PF00026	0.409
TRG_Pf-PMV_PEXEL_1	95	100	PF00026	0.487

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I6Z6	Leptomonas seymouri	67%	99%
A0A0S4JV63	Bodo saltans	38%	100%
A0A1X0P3Z7	Trypanosomatidae	50%	100%
A0A3S7X0G6	Leishmania donovani	83%	100%
A0A422NMT7	Trypanosoma rangeli	51%	100%
D0A5R5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	100%
E9AD40	Leishmania major	82%	100%
E9AHD3	Leishmania infantum	83%	100%
E9AYW4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%