LeishMANIAdb
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Si:ch211-160o17.6

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Si:ch211-160o17.6
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HFG4_LEIBR
TriTrypDb:
LbrM.27.0490 , LBRM2903_270010300
Length:
140

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HFG4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HFG4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 110 114 PF00656 0.384
CLV_NRD_NRD_1 111 113 PF00675 0.497
CLV_PCSK_KEX2_1 111 113 PF00082 0.562
CLV_PCSK_KEX2_1 120 122 PF00082 0.516
CLV_PCSK_PC1ET2_1 120 122 PF00082 0.516
CLV_PCSK_SKI1_1 47 51 PF00082 0.523
DEG_MDM2_SWIB_1 9 16 PF02201 0.583
DEG_Nend_UBRbox_2 1 3 PF02207 0.575
DEG_SPOP_SBC_1 135 139 PF00917 0.579
DOC_MAPK_gen_1 92 100 PF00069 0.550
DOC_USP7_MATH_1 134 138 PF00917 0.594
DOC_USP7_MATH_1 82 86 PF00917 0.439
DOC_USP7_UBL2_3 83 87 PF12436 0.525
LIG_FHA_1 113 119 PF00498 0.384
LIG_FHA_2 108 114 PF00498 0.377
LIG_LIR_Gen_1 59 68 PF02991 0.534
LIG_LIR_Gen_1 95 100 PF02991 0.451
LIG_LIR_Nem_3 10 16 PF02991 0.540
LIG_LIR_Nem_3 59 64 PF02991 0.516
LIG_LIR_Nem_3 95 99 PF02991 0.441
LIG_NRBOX 38 44 PF00104 0.533
LIG_PDZ_Class_1 135 140 PF00595 0.414
LIG_Pex14_2 9 13 PF04695 0.512
LIG_SH2_STAT5 56 59 PF00017 0.352
LIG_SUMO_SIM_anti_2 38 43 PF11976 0.534
MOD_GlcNHglycan 24 27 PF01048 0.574
MOD_GSK3_1 107 114 PF00069 0.375
MOD_NEK2_1 1 6 PF00069 0.666
MOD_NEK2_2 82 87 PF00069 0.544
MOD_PKA_1 111 117 PF00069 0.624
MOD_PKA_2 111 117 PF00069 0.624
MOD_Plk_1 100 106 PF00069 0.475
MOD_Plk_2-3 48 54 PF00069 0.538
TRG_DiLeu_BaEn_1 38 43 PF01217 0.534
TRG_DiLeu_BaEn_1 60 65 PF01217 0.532
TRG_NES_CRM1_1 22 36 PF08389 0.367

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P666 Leptomonas seymouri 69% 99%
A0A1X0P462 Trypanosomatidae 37% 100%
A0A3Q8IE74 Leishmania donovani 82% 100%
A0A422NTD2 Trypanosoma rangeli 35% 100%
A4I2M6 Leishmania infantum 81% 100%
E9AD17 Leishmania major 82% 100%
E9AYU2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 84% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS