DUF4083 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HFC5_LEIBR

TriTrypDb:

LbrM.27.0070 , LBRM2903_270005900

Length:


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	4
GO:0110165	cellular anatomical entity	1	4

A4HFC5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HFC5


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	8	12	PF00656	0.360
CLV_NRD_NRD_1	44	46	PF00675	0.394
CLV_NRD_NRD_1	47	49	PF00675	0.394
CLV_NRD_NRD_1	66	68	PF00675	0.463
CLV_PCSK_KEX2_1	44	46	PF00082	0.435
CLV_PCSK_KEX2_1	68	70	PF00082	0.438
CLV_PCSK_PC1ET2_1	68	70	PF00082	0.549
CLV_PCSK_SKI1_1	48	52	PF00082	0.443
DOC_MAPK_RevD_3	29	45	PF00069	0.582
LIG_14-3-3_CanoR_1	60	65	PF00244	0.570
LIG_BRCT_BRCA1_1	11	15	PF00533	0.522
LIG_deltaCOP1_diTrp_1	20	27	PF00928	0.371
LIG_EH1_1	25	33	PF00400	0.280
LIG_GBD_Chelix_1	24	32	PF00786	0.350
LIG_LIR_Gen_1	12	19	PF02991	0.436
LIG_LIR_Gen_1	20	31	PF02991	0.337
LIG_LIR_Nem_3	12	18	PF02991	0.437
LIG_LIR_Nem_3	20	26	PF02991	0.346
LIG_Pex14_1	23	27	PF04695	0.280
MOD_CK1_1	13	19	PF00069	0.515
MOD_CK1_1	63	69	PF00069	0.744
MOD_GSK3_1	5	12	PF00069	0.420
MOD_Plk_1	10	16	PF00069	0.468
MOD_Plk_4	10	16	PF00069	0.468
TRG_ENDOCYTIC_2	61	64	PF00928	0.571
TRG_Pf-PMV_PEXEL_1	48	53	PF00026	0.443


Protein	Taxonomy	Sequence identity	Coverage
A4I2K2	Leishmania infantum	83%	100%
C9ZKU2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	95%
E9ACY3	Leishmania major	80%	66%