Putative ribosomal protein L38

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ribosomal protein L38, putative

Species:

Leishmania braziliensis

UniProt:

A4HF66_LEIBR

TriTrypDb:

LbrM.26.2140 , LBRM2903_260026300

Length:

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 30

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	10
GO:0032991	protein-containing complex	1	11
GO:0043226	organelle	2	10
GO:0043228	non-membrane-bounded organelle	3	10
GO:0043229	intracellular organelle	3	10
GO:0043232	intracellular non-membrane-bounded organelle	4	10
GO:0110165	cellular anatomical entity	1	11
GO:1990904	ribonucleoprotein complex	2	11
GO:0005737	cytoplasm	2	1
GO:0015934	large ribosomal subunit	4	1
GO:0022625	cytosolic large ribosomal subunit	5	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043233	organelle lumen	3	1
GO:0044391	ribosomal subunit	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1

Expansion

Sequence features

A4HF66

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HF66

Function

Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	11
GO:0006518	peptide metabolic process	4	11
GO:0006807	nitrogen compound metabolic process	2	11
GO:0008152	metabolic process	1	11
GO:0009058	biosynthetic process	2	11
GO:0009059	macromolecule biosynthetic process	4	11
GO:0009987	cellular process	1	11
GO:0019538	protein metabolic process	3	11
GO:0034641	cellular nitrogen compound metabolic process	3	11
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	11
GO:0043043	peptide biosynthetic process	5	11
GO:0043170	macromolecule metabolic process	3	11
GO:0043603	amide metabolic process	3	11
GO:0043604	amide biosynthetic process	4	11
GO:0044237	cellular metabolic process	2	11
GO:0044238	primary metabolic process	2	11
GO:0044249	cellular biosynthetic process	3	11
GO:0044260	obsolete cellular macromolecule metabolic process	3	11
GO:0044271	cellular nitrogen compound biosynthetic process	4	11
GO:0071704	organic substance metabolic process	2	11
GO:1901564	organonitrogen compound metabolic process	3	11
GO:1901566	organonitrogen compound biosynthetic process	4	11
GO:1901576	organic substance biosynthetic process	3	11
GO:0016043	cellular component organization	3	1
GO:0022607	cellular component assembly	4	1
GO:0022618	ribonucleoprotein complex assembly	6	1
GO:0043933	protein-containing complex organization	4	1
GO:0065003	protein-containing complex assembly	5	1
GO:0071826	ribonucleoprotein complex subunit organization	5	1
GO:0071840	cellular component organization or biogenesis	2	1

Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	11
GO:0005198	structural molecule activity	1	11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	16	20	PF00656	0.335
CLV_NRD_NRD_1	16	18	PF00675	0.310
CLV_PCSK_KEX2_1	26	28	PF00082	0.232
CLV_PCSK_PC1ET2_1	26	28	PF00082	0.232
CLV_PCSK_SKI1_1	21	25	PF00082	0.318
CLV_PCSK_SKI1_1	3	7	PF00082	0.334
CLV_PCSK_SKI1_1	9	13	PF00082	0.333
DOC_MAPK_gen_1	17	25	PF00069	0.310
DOC_MAPK_gen_1	37	47	PF00069	0.335
DOC_MAPK_gen_1	6	14	PF00069	0.310
DOC_USP7_MATH_1	13	17	PF00917	0.335
DOC_USP7_UBL2_3	51	55	PF12436	0.310
LIG_14-3-3_CanoR_1	40	46	PF00244	0.336
LIG_FHA_1	42	48	PF00498	0.335
LIG_FHA_2	5	11	PF00498	0.424
LIG_LIR_LC3C_4	44	47	PF02991	0.335
LIG_LIR_Nem_3	10	14	PF02991	0.310
LIG_SH2_CRK	43	47	PF00017	0.310
LIG_SH2_STAP1	43	47	PF00017	0.310
LIG_SH2_STAT5	41	44	PF00017	0.335
LIG_SUMO_SIM_par_1	43	49	PF11976	0.354
MOD_CK2_1	4	10	PF00069	0.372
MOD_GlcNHglycan	29	32	PF01048	0.429
MOD_GSK3_1	56	63	PF00069	0.335
MOD_GSK3_1	70	77	PF00069	0.548
MOD_PKA_2	36	42	PF00069	0.313
MOD_Plk_1	56	62	PF00069	0.335
MOD_Plk_2-3	4	10	PF00069	0.370
MOD_Plk_4	41	47	PF00069	0.310
TRG_ENDOCYTIC_2	43	46	PF00928	0.310
TRG_Pf-PMV_PEXEL_1	6	10	PF00026	0.333

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HWQ9	Leptomonas seymouri	96%	100%
A0A0S4J050	Bodo saltans	80%	100%
A0A1D8PG16	Candida albicans (strain SC5314 / ATCC MYA-2876)	47%	100%
A0A451EJM9	Leishmania donovani	96%	100%
A2I469	Maconellicoccus hirsutus	60%	100%
A4H3J7	Leishmania braziliensis	99%	100%
A4HRT6	Leishmania infantum	96%	100%
A6N9N3	Ornithodoros parkeri	52%	100%
A7L6A2	Artemia franciscana	49%	100%
D0A237	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	83%	100%
E9AJR0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
O17570	Caenorhabditis elegans	57%	100%
O22860	Arabidopsis thaliana	56%	100%
O61570	Ostertagia ostertagi	54%	100%
P46291	Solanum lycopersicum	55%	100%
P49167	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	43%	100%
P63173	Homo sapiens	56%	100%
P63174	Rattus norvegicus	56%	100%
Q09900	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	52%	100%
Q09JT4	Argas monolakensis	52%	100%
Q1HRT4	Aedes aegypti	60%	100%
Q32PB9	Bos taurus	56%	100%
Q4GX86	Timarcha balearica	57%	100%
Q4GX87	Julodis onopordi	57%	100%
Q4N921	Theileria parva	48%	100%
Q4PMD1	Ixodes scapularis	55%	100%
Q4Q8X0	Leishmania major	96%	100%
Q4UGN5	Theileria annulata	43%	100%
Q55GJ7	Dictyostelium discoideum	46%	100%
Q56FC8	Lysiphlebus testaceipes	57%	100%
Q5MGL3	Lonomia obliqua	57%	100%
Q5UAP8	Bombyx mori	58%	100%
Q6F450	Plutella xylostella	58%	100%
Q6XIM7	Drosophila yakuba	63%	100%
Q7Q0U1	Anopheles gambiae	58%	100%
Q8HXB9	Macaca fascicularis	56%	100%
Q95V84	Branchiostoma belcheri	56%	100%
Q962S5	Spodoptera frugiperda	57%	100%
Q9C2B9	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	44%	100%
Q9JJI8	Mus musculus	56%	100%
Q9USR7	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	51%	100%
Q9W5N2	Drosophila melanogaster	63%	100%
V5DAL2	Trypanosoma cruzi	90%	100%