LeishMANIAdb
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CX9C domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
CX9C domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HF58_LEIBR
TriTrypDb:
LbrM.26.2060 , LBRM2903_260025300
Length:
113

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HF58
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HF58

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 23 27 PF00082 0.504
CLV_PCSK_SKI1_1 93 97 PF00082 0.507
DEG_APCC_KENBOX_2 81 85 PF00400 0.478
DOC_USP7_UBL2_3 55 59 PF12436 0.557
DOC_USP7_UBL2_3 71 75 PF12436 0.450
LIG_14-3-3_CanoR_1 44 53 PF00244 0.518
LIG_BIR_II_1 1 5 PF00653 0.539
LIG_BRCT_BRCA1_1 77 81 PF00533 0.532
LIG_deltaCOP1_diTrp_1 74 81 PF00928 0.492
LIG_FHA_1 89 95 PF00498 0.460
LIG_SH2_SRC 49 52 PF00017 0.456
LIG_SH2_STAT3 19 22 PF00017 0.455
LIG_SH2_STAT5 49 52 PF00017 0.417
LIG_SH2_STAT5 99 102 PF00017 0.449
MOD_CK1_1 2 8 PF00069 0.496
MOD_GlcNHglycan 46 49 PF01048 0.474
MOD_LATS_1 106 112 PF00433 0.482
MOD_PKA_2 2 8 PF00069 0.503
TRG_Pf-PMV_PEXEL_1 93 97 PF00026 0.513

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P445 Leptomonas seymouri 88% 100%
A0A3R7LKD8 Trypanosoma rangeli 73% 98%
A0A3S5H7G7 Leishmania donovani 89% 100%
A4I2E2 Leishmania infantum 89% 100%
C9ZX65 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 70% 100%
E9AYJ4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 100%
Q4Q8X8 Leishmania major 88% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS