LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HF56_LEIBR
TriTrypDb:
LbrM.26.2040 , LBRM2903_260025100 *
Length:
4199

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Cellular components
TermNameLevelCount
GO:0005634 nucleus 5 1
GO:0005737 cytoplasm 2 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1
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Expansion

Sequence features

A4HF56
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
TermNameLevelCount
GO:0006468 protein phosphorylation 5 1
GO:0006793 phosphorus metabolic process 3 1
GO:0006796 phosphate-containing compound metabolic process 4 1
GO:0006807 nitrogen compound metabolic process 2 1
GO:0007165 signal transduction 2 1
GO:0008152 metabolic process 1 1
GO:0009987 cellular process 1 1
GO:0016310 phosphorylation 5 1
GO:0018105 peptidyl-serine phosphorylation 6 1
GO:0018193 peptidyl-amino acid modification 5 1
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Molecular functions
TermNameLevelCount
GO:0003824 catalytic activity 1 1
GO:0004672 protein kinase activity 3 1
GO:0004674 protein serine/threonine kinase activity 4 1
GO:0004683 calmodulin-dependent protein kinase activity 5 1
GO:0005488 binding 1 1
GO:0005515 protein binding 2 1
GO:0005516 calmodulin binding 3 1
GO:0009931 calcium-dependent protein serine/threonine kinase activity 5 1
GO:0010857 calcium-dependent protein kinase activity 4 1
GO:0016301 kinase activity 4 1
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 124 128 PF00656 0.369
CLV_C14_Caspase3-7 1391 1395 PF00656 0.414
CLV_C14_Caspase3-7 1423 1427 PF00656 0.456
CLV_C14_Caspase3-7 2614 2618 PF00656 0.448
CLV_C14_Caspase3-7 2870 2874 PF00656 0.541
CLV_C14_Caspase3-7 3149 3153 PF00656 0.522
CLV_C14_Caspase3-7 3436 3440 PF00656 0.460
CLV_C14_Caspase3-7 3971 3975 PF00656 0.570
CLV_C14_Caspase3-7 466 470 PF00656 0.398
CLV_NRD_NRD_1 1034 1036 PF00675 0.282
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8IPE6 Leishmania donovani 57% 98%
E9AYJ2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 57% 100%
Q4Q8Y0 Leishmania major 56% 98%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS