LeishMANIAdb
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DUF772 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
DUF772 domain-containing protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania braziliensis
UniProt:
A4HF53_LEIBR
TriTrypDb:
LbrM.26.2010 , LBRM2903_260024800
Length:
113

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HF53
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HF53

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 87 91 PF00656 0.526
CLV_NRD_NRD_1 97 99 PF00675 0.568
CLV_PCSK_KEX2_1 99 101 PF00082 0.586
CLV_PCSK_PC1ET2_1 99 101 PF00082 0.429
DEG_Nend_UBRbox_3 1 3 PF02207 0.644
DOC_CYCLIN_yCln2_LP_2 71 77 PF00134 0.705
DOC_MAPK_DCC_7 40 49 PF00069 0.444
DOC_MAPK_MEF2A_6 40 49 PF00069 0.444
DOC_MAPK_MEF2A_6 72 81 PF00069 0.561
DOC_PP2B_LxvP_1 71 74 PF13499 0.727
DOC_USP7_MATH_1 48 52 PF00917 0.593
LIG_EH1_1 55 63 PF00400 0.429
LIG_FHA_1 80 86 PF00498 0.369
LIG_FHA_2 55 61 PF00498 0.575
LIG_LIR_Gen_1 25 33 PF02991 0.540
LIG_LIR_Gen_1 91 101 PF02991 0.562
LIG_LIR_Nem_3 25 30 PF02991 0.654
LIG_LIR_Nem_3 91 97 PF02991 0.479
LIG_MYND_1 42 46 PF01753 0.607
LIG_Pex14_2 84 88 PF04695 0.638
LIG_SH2_CRK 27 31 PF00017 0.535
LIG_SH2_CRK 94 98 PF00017 0.570
LIG_SH2_SRC 94 97 PF00017 0.410
LIG_SH2_STAT5 83 86 PF00017 0.525
LIG_SH3_3 35 41 PF00018 0.586
LIG_SH3_3 70 76 PF00018 0.666
LIG_SUMO_SIM_par_1 13 19 PF11976 0.570
LIG_TRAF2_1 57 60 PF00917 0.483
MOD_CK1_1 63 69 PF00069 0.635
MOD_CK2_1 54 60 PF00069 0.565
MOD_CK2_1 63 69 PF00069 0.490
MOD_GlcNHglycan 62 65 PF01048 0.625
MOD_GlcNHglycan 90 93 PF01048 0.531
MOD_N-GLC_1 1 6 PF02516 0.501
MOD_NEK2_1 1 6 PF00069 0.502
MOD_NEK2_1 16 21 PF00069 0.499
MOD_NEK2_1 79 84 PF00069 0.531
MOD_PIKK_1 102 108 PF00454 0.604
MOD_PKA_2 88 94 PF00069 0.530
MOD_PKB_1 98 106 PF00069 0.432
MOD_Plk_1 1 7 PF00069 0.494
MOD_Plk_1 100 106 PF00069 0.590
TRG_ENDOCYTIC_2 27 30 PF00928 0.533
TRG_ENDOCYTIC_2 94 97 PF00928 0.481
TRG_ER_diArg_1 97 100 PF00400 0.429

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8ICY6 Leishmania donovani 70% 100%
A4I2D7 Leishmania infantum 70% 100%
E9AYI9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 69% 100%
Q4Q8Y3 Leishmania major 68% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS