4HBT domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

Thioesterase-like superfamily, putative

Species:

Leishmania braziliensis

UniProt:

A4HF38_LEIBR

TriTrypDb:

LbrM.26.1860 , LBRM2903_260023300

Length:

154

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HF38

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HF38

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	135	141	PF00089	0.549
CLV_NRD_NRD_1	152	154	PF00675	0.549
CLV_PCSK_KEX2_1	152	154	PF00082	0.549
DOC_CKS1_1	59	64	PF01111	0.767
DOC_PP1_RVXF_1	136	142	PF00149	0.549
DOC_PP2B_LxvP_1	31	34	PF13499	0.742
DOC_PP4_FxxP_1	69	72	PF00568	0.750
DOC_USP7_MATH_1	21	25	PF00917	0.719
DOC_USP7_MATH_1	38	42	PF00917	0.451
DOC_WW_Pin1_4	58	63	PF00397	0.767
LIG_14-3-3_CanoR_1	136	142	PF00244	0.549
LIG_EVH1_2	65	69	PF00568	0.747
LIG_FHA_1	130	136	PF00498	0.549
LIG_FHA_1	53	59	PF00498	0.742
LIG_LIR_Gen_1	111	120	PF02991	0.549
LIG_LIR_Gen_1	80	91	PF02991	0.693
LIG_LIR_Nem_3	103	108	PF02991	0.549
LIG_LIR_Nem_3	111	116	PF02991	0.410
LIG_LIR_Nem_3	126	130	PF02991	0.287
LIG_LIR_Nem_3	80	86	PF02991	0.703
LIG_Pex14_2	69	73	PF04695	0.753
LIG_Pex14_2	79	83	PF04695	0.539
LIG_PTB_Apo_2	107	114	PF02174	0.549
LIG_PTB_Phospho_1	107	113	PF10480	0.549
LIG_SH2_CRK	96	100	PF00017	0.668
LIG_SH2_STAT5	113	116	PF00017	0.252
LIG_SH2_STAT5	96	99	PF00017	0.663
LIG_SH3_3	59	65	PF00018	0.766
LIG_WW_3	65	69	PF00397	0.747
MOD_CDK_SPK_2	58	63	PF00069	0.767
MOD_CK1_1	144	150	PF00069	0.549
MOD_CK2_1	33	39	PF00069	0.753
MOD_GlcNHglycan	27	30	PF01048	0.751
MOD_GSK3_1	137	144	PF00069	0.549
MOD_GSK3_1	21	28	PF00069	0.726
MOD_N-GLC_1	108	113	PF02516	0.549
MOD_NEK2_1	146	151	PF00069	0.549
MOD_PKA_2	137	143	PF00069	0.549
MOD_PKA_2	21	27	PF00069	0.723
MOD_Plk_1	144	150	PF00069	0.549
MOD_Plk_1	38	44	PF00069	0.742
MOD_Plk_4	123	129	PF00069	0.549
MOD_Plk_4	137	143	PF00069	0.305
MOD_Plk_4	38	44	PF00069	0.742
MOD_ProDKin_1	58	64	PF00069	0.764
TRG_ENDOCYTIC_2	105	108	PF00928	0.392
TRG_ENDOCYTIC_2	113	116	PF00928	0.252
TRG_ENDOCYTIC_2	96	99	PF00928	0.663
TRG_ER_diArg_1	135	138	PF00400	0.549
TRG_ER_diArg_1	20	23	PF00400	0.714
TRG_NES_CRM1_1	89	103	PF08389	0.652
TRG_Pf-PMV_PEXEL_1	100	104	PF00026	0.644
TRG_Pf-PMV_PEXEL_1	15	19	PF00026	0.697
TRG_Pf-PMV_PEXEL_1	75	80	PF00026	0.727