Putative 40S ribosomal protein S33

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

40S ribosomal protein S33, putative

Species:

Leishmania braziliensis

UniProt:

A4HF18_LEIBR

TriTrypDb:

LbrM.26.1660 , LBRM2903_260022200

Length:

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 32

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 8
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	9
GO:0043226	organelle	2	9
GO:0043228	non-membrane-bounded organelle	3	9
GO:0043229	intracellular organelle	3	9
GO:0043232	intracellular non-membrane-bounded organelle	4	9
GO:0110165	cellular anatomical entity	1	10
GO:0005737	cytoplasm	2	1
GO:0015935	small ribosomal subunit	4	1
GO:0022627	cytosolic small ribosomal subunit	5	1
GO:0032991	protein-containing complex	1	1
GO:0044391	ribosomal subunit	3	1
GO:1990904	ribonucleoprotein complex	2	1

Expansion

Sequence features

A4HF18

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HF18

Function

Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	10
GO:0006518	peptide metabolic process	4	10
GO:0006807	nitrogen compound metabolic process	2	10
GO:0008152	metabolic process	1	10
GO:0009058	biosynthetic process	2	10
GO:0009059	macromolecule biosynthetic process	4	10
GO:0009987	cellular process	1	10
GO:0019538	protein metabolic process	3	10
GO:0034641	cellular nitrogen compound metabolic process	3	10
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	10
GO:0043043	peptide biosynthetic process	5	10
GO:0043170	macromolecule metabolic process	3	10
GO:0043603	amide metabolic process	3	10
GO:0043604	amide biosynthetic process	4	10
GO:0044237	cellular metabolic process	2	10
GO:0044238	primary metabolic process	2	10
GO:0044249	cellular biosynthetic process	3	10
GO:0044260	obsolete cellular macromolecule metabolic process	3	10
GO:0044271	cellular nitrogen compound biosynthetic process	4	10
GO:0071704	organic substance metabolic process	2	10
GO:1901564	organonitrogen compound metabolic process	3	10
GO:1901566	organonitrogen compound biosynthetic process	4	10
GO:1901576	organic substance biosynthetic process	3	10
GO:0000028	ribosomal small subunit assembly	7	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006364	rRNA processing	8	1
GO:0006396	RNA processing	6	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0016043	cellular component organization	3	1
GO:0016070	RNA metabolic process	5	1
GO:0016072	rRNA metabolic process	7	1
GO:0022607	cellular component assembly	4	1
GO:0022618	ribonucleoprotein complex assembly	6	1
GO:0030490	maturation of SSU-rRNA	9	1
GO:0034470	ncRNA processing	7	1
GO:0034660	ncRNA metabolic process	6	1
GO:0043933	protein-containing complex organization	4	1
GO:0046483	heterocycle metabolic process	3	1
GO:0065003	protein-containing complex assembly	5	1
GO:0071826	ribonucleoprotein complex subunit organization	5	1
GO:0071840	cellular component organization or biogenesis	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	10
GO:0005198	structural molecule activity	1	10

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	4	8	PF00656	0.692
CLV_NRD_NRD_1	84	86	PF00675	0.267
CLV_PCSK_KEX2_1	84	86	PF00082	0.267
CLV_PCSK_SKI1_1	62	66	PF00082	0.274
DEG_APCC_KENBOX_2	68	72	PF00400	0.549
DOC_USP7_UBL2_3	5	9	PF12436	0.596
DOC_USP7_UBL2_3	65	69	PF12436	0.467
DOC_WW_Pin1_4	50	55	PF00397	0.487
LIG_14-3-3_CanoR_1	37	47	PF00244	0.474
LIG_BIR_II_1	1	5	PF00653	0.719
LIG_FHA_1	9	15	PF00498	0.690
LIG_FHA_2	77	83	PF00498	0.467
LIG_NRP_CendR_1	84	87	PF00754	0.267
LIG_SH3_3	61	67	PF00018	0.467
LIG_SUMO_SIM_anti_2	72	80	PF11976	0.467
LIG_SUMO_SIM_par_1	72	80	PF11976	0.474
MOD_CK2_1	72	78	PF00069	0.471
MOD_GSK3_1	72	79	PF00069	0.492
MOD_N-GLC_1	38	43	PF02516	0.267
MOD_N-GLC_1	56	61	PF02516	0.285
MOD_NEK2_1	1	6	PF00069	0.766
MOD_NEK2_1	31	36	PF00069	0.484
MOD_PIKK_1	38	44	PF00454	0.467
MOD_Plk_1	38	44	PF00069	0.467
MOD_Plk_1	56	62	PF00069	0.485
MOD_Plk_2-3	72	78	PF00069	0.485
MOD_Plk_4	72	78	PF00069	0.502
MOD_ProDKin_1	50	56	PF00069	0.487
MOD_SUMO_rev_2	3	11	PF00179	0.664
TRG_ER_diArg_1	43	46	PF00400	0.485
TRG_ER_diArg_1	84	87	PF00400	0.467

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3M7	Leptomonas seymouri	95%	91%
A0A0S4JWV7	Bodo saltans	79%	97%
A0A1D8PQN0	Candida albicans (strain SC5314 / ATCC MYA-2876)	70%	100%
A0A1X0NS23	Trypanosomatidae	93%	73%
A0A3Q8ID00	Leishmania donovani	99%	100%
A1RS33	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	43%	100%
A1RXH2	Thermofilum pendens (strain DSM 2475 / Hrk 5)	47%	100%
A4FYI6	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	47%	100%
A4WLP1	Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6)	45%	100%
A4YCQ2	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	50%	100%
A6USH4	Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)	48%	100%
A6UT50	Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)	45%	100%
A6VJU6	Methanococcus maripaludis (strain C7 / ATCC BAA-1331)	47%	100%
A9A7E6	Methanococcus maripaludis (strain C6 / ATCC BAA-1332)	47%	100%
B1L5N5	Korarchaeum cryptofilum (strain OPF8)	46%	100%
B1Y9V2	Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / NBRC 100436 / V24Sta)	45%	100%
B9LPY3	Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34)	40%	100%
C9ZRP5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	91%	84%
E9AYE2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
O26356	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	43%	100%
O29493	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	47%	100%
O61590	Ostertagia ostertagi	61%	100%
P0C0X0	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	70%	100%
P0CT79	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	66%	100%
P0CT80	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	66%	100%
P33285	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	69%	100%
P33286	Kluyveromyces marxianus	69%	100%
P34789	Arabidopsis thaliana	57%	100%
P46302	Zea mays	58%	100%
P54065	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	52%	100%
P57711	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	47%	100%
P61029	Pyrococcus abyssi (strain GE5 / Orsay)	46%	100%
P61030	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	46%	100%
P61031	Nanoarchaeum equitans (strain Kin4-M)	48%	99%
P62857	Homo sapiens	61%	100%
P62858	Mus musculus	61%	100%
P62859	Rattus norvegicus	61%	100%
Q3E7X9	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	70%	100%
Q4JAV1	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	44%	100%
Q4Q931	Leishmania major	99%	100%
Q54MZ5	Dictyostelium discoideum	54%	100%
Q56JX6	Bos taurus	61%	100%
Q5JGR4	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	41%	100%
Q6EV21	Papilio dardanus	56%	100%
Q6FLC3	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	70%	100%
Q6KZI6	Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)	45%	100%
Q6LZI8	Methanococcus maripaludis (strain S2 / LL)	48%	100%
Q6PBK3	Danio rerio	62%	100%
Q6PS50	Bombyx mori	56%	100%
Q6QAT1	Sus scrofa	61%	100%
Q74ZD8	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	70%	100%
Q7S6W5	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	62%	100%
Q8TVE7	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	51%	100%
Q8U159	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	46%	100%
Q8ZTA7	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	45%	100%
Q90YP3	Ictalurus punctatus	62%	100%
Q95Y04	Caenorhabditis elegans	53%	100%
Q962Q2	Spodoptera frugiperda	56%	100%
Q975Z8	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	53%	100%
Q97BK7	Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)	42%	100%
Q980Q5	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	52%	100%
Q9N9V5	Leishmania infantum	99%	100%
Q9SR73	Arabidopsis thaliana	57%	100%
Q9W334	Drosophila melanogaster	59%	100%
Q9Y9A6	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	43%	100%