Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HEW6_LEIBR

TriTrypDb:

LbrM.26.1120 , LBRM2903_260016200

Length:

126


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	8
GO:0110165	cellular anatomical entity	1	8

A4HEW6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HEW6


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	101	103	PF00675	0.563
CLV_NRD_NRD_1	11	13	PF00675	0.395
CLV_NRD_NRD_1	3	5	PF00675	0.391
CLV_PCSK_KEX2_1	101	103	PF00082	0.563
CLV_PCSK_KEX2_1	11	13	PF00082	0.395
CLV_PCSK_KEX2_1	3	5	PF00082	0.391
CLV_PCSK_SKI1_1	38	42	PF00082	0.324
DEG_Nend_Nbox_1	1	3	PF02207	0.602
DOC_CDC14_PxL_1	71	79	PF14671	0.410
DOC_PP1_RVXF_1	99	106	PF00149	0.448
DOC_WW_Pin1_4	10	15	PF00397	0.592
LIG_14-3-3_CanoR_1	3	10	PF00244	0.587
LIG_FHA_1	74	80	PF00498	0.343
LIG_LIR_Apic_2	21	26	PF02991	0.592
LIG_LIR_Gen_1	76	84	PF02991	0.304
LIG_LIR_Nem_3	76	81	PF02991	0.304
LIG_Pex14_2	80	84	PF04695	0.300
LIG_SH2_CRK	23	27	PF00017	0.662
LIG_SH2_STAT5	112	115	PF00017	0.414
LIG_SH2_STAT5	71	74	PF00017	0.286
LIG_SH2_STAT5	78	81	PF00017	0.326
LIG_UBA3_1	79	87	PF00899	0.410
LIG_WW_3	98	102	PF00397	0.384
MOD_CDK_SPxK_1	10	16	PF00069	0.592
MOD_CK1_1	34	40	PF00069	0.617
MOD_CK1_1	73	79	PF00069	0.410
MOD_CK2_1	15	21	PF00069	0.596
MOD_GlcNHglycan	17	20	PF01048	0.393
MOD_GlcNHglycan	34	37	PF01048	0.434
MOD_GlcNHglycan	72	75	PF01048	0.410
MOD_NEK2_1	117	122	PF00069	0.445
MOD_NEK2_1	2	7	PF00069	0.592
MOD_PIKK_1	2	8	PF00454	0.597
MOD_PKA_2	15	21	PF00069	0.596
MOD_PKA_2	2	8	PF00069	0.589
MOD_Plk_2-3	104	110	PF00069	0.406
MOD_Plk_4	46	52	PF00069	0.507
MOD_Plk_4	73	79	PF00069	0.314
MOD_ProDKin_1	10	16	PF00069	0.592
MOD_SUMO_for_1	26	29	PF00179	0.621
TRG_DiLeu_BaEn_4	108	114	PF01217	0.397
TRG_ENDOCYTIC_2	78	81	PF00928	0.297
TRG_ER_diArg_1	10	12	PF00400	0.598
TRG_ER_diArg_1	100	102	PF00400	0.363
TRG_ER_diArg_1	2	4	PF00400	0.596
TRG_NES_CRM1_1	55	69	PF08389	0.505


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I0S5	Leptomonas seymouri	82%	100%
A0A0S4JNG0	Bodo saltans	48%	100%
A0A1X0NTS3	Trypanosomatidae	62%	100%
A0A3Q8IP44	Leishmania donovani	93%	100%
A0A422NSR5	Trypanosoma rangeli	60%	100%
A4I239	Leishmania infantum	93%	100%
C9ZRW5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	62%	100%
E9AY89	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
Q4Q984	Leishmania major	92%	100%