LeishMANIAdb
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Pentapeptide repeat-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Pentapeptide repeat-containing protein
Gene product:
Pentapeptide repeats (9 copies), putative
Species:
Leishmania braziliensis
UniProt:
A4HES5_LEIBR
TriTrypDb:
LbrM.26.0710 , LBRM2903_260011900 *
Length:
521

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HES5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HES5

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 146 150 PF00656 0.304
CLV_C14_Caspase3-7 306 310 PF00656 0.613
CLV_C14_Caspase3-7 57 61 PF00656 0.518
CLV_NRD_NRD_1 111 113 PF00675 0.541
CLV_NRD_NRD_1 284 286 PF00675 0.367
CLV_NRD_NRD_1 3 5 PF00675 0.500
CLV_NRD_NRD_1 410 412 PF00675 0.462
CLV_NRD_NRD_1 68 70 PF00675 0.515
CLV_NRD_NRD_1 90 92 PF00675 0.614
CLV_PCSK_KEX2_1 111 113 PF00082 0.541
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I5M8 Leptomonas seymouri 40% 100%
A0A3Q8IC33 Leishmania donovani 65% 100%
A4I202 Leishmania infantum 65% 100%
E9AY49 Leishmania mexicana (strain MHOM/GT/2001/U1103) 67% 100%
Q4Q9C4 Leishmania major 64% 98%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS