Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HEQ8_LEIBR

TriTrypDb:

LbrM.26.0540 , LBRM2903_260010200

Length:

558

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HEQ8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HEQ8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	150	154	PF00656	0.301
CLV_C14_Caspase3-7	357	361	PF00656	0.445
CLV_C14_Caspase3-7	380	384	PF00656	0.401
CLV_NRD_NRD_1	147	149	PF00675	0.285
CLV_NRD_NRD_1	24	26	PF00675	0.498
CLV_NRD_NRD_1	281	283	PF00675	0.502
CLV_NRD_NRD_1	32	34	PF00675	0.509
CLV_NRD_NRD_1	60	62	PF00675	0.485
CLV_NRD_NRD_1	80	82	PF00675	0.451
CLV_PCSK_FUR_1	57	61	PF00082	0.487
CLV_PCSK_KEX2_1	147	149	PF00082	0.285
CLV_PCSK_KEX2_1	202	204	PF00082	0.282
CLV_PCSK_KEX2_1	23	25	PF00082	0.505
CLV_PCSK_KEX2_1	281	283	PF00082	0.502
CLV_PCSK_KEX2_1	32	34	PF00082	0.509
CLV_PCSK_KEX2_1	59	61	PF00082	0.491
CLV_PCSK_KEX2_1	80	82	PF00082	0.451
CLV_PCSK_PC1ET2_1	202	204	PF00082	0.282
CLV_PCSK_SKI1_1	371	375	PF00082	0.271
CLV_PCSK_SKI1_1	61	65	PF00082	0.475
DEG_SPOP_SBC_1	417	421	PF00917	0.508
DOC_CKS1_1	393	398	PF01111	0.521
DOC_CKS1_1	403	408	PF01111	0.525
DOC_CYCLIN_RxL_1	440	452	PF00134	0.484
DOC_CYCLIN_RxL_1	536	545	PF00134	0.285
DOC_MAPK_gen_1	440	450	PF00069	0.485
DOC_MAPK_MEF2A_6	259	267	PF00069	0.241
DOC_PP2B_LxvP_1	224	227	PF13499	0.390
DOC_PP4_FxxP_1	477	480	PF00568	0.458
DOC_USP7_MATH_1	118	122	PF00917	0.339
DOC_USP7_MATH_1	294	298	PF00917	0.458
DOC_USP7_MATH_1	343	347	PF00917	0.524
DOC_USP7_MATH_1	97	101	PF00917	0.467
DOC_USP7_UBL2_3	287	291	PF12436	0.473
DOC_WW_Pin1_4	339	344	PF00397	0.512
DOC_WW_Pin1_4	378	383	PF00397	0.380
DOC_WW_Pin1_4	386	391	PF00397	0.493
DOC_WW_Pin1_4	392	397	PF00397	0.520
DOC_WW_Pin1_4	402	407	PF00397	0.525
DOC_WW_Pin1_4	461	466	PF00397	0.502
DOC_WW_Pin1_4	95	100	PF00397	0.459
LIG_14-3-3_CanoR_1	147	156	PF00244	0.287
LIG_14-3-3_CanoR_1	235	241	PF00244	0.309
LIG_14-3-3_CanoR_1	32	38	PF00244	0.501
LIG_14-3-3_CanoR_1	324	334	PF00244	0.506
LIG_14-3-3_CanoR_1	418	426	PF00244	0.508
LIG_14-3-3_CanoR_1	446	451	PF00244	0.480
LIG_14-3-3_CanoR_1	472	476	PF00244	0.470
LIG_14-3-3_CanoR_1	80	87	PF00244	0.428
LIG_BRCT_BRCA1_1	291	295	PF00533	0.471
LIG_BRCT_BRCA1_1	326	330	PF00533	0.497
LIG_BRCT_BRCA1_1	473	477	PF00533	0.469
LIG_Clathr_ClatBox_1	173	177	PF01394	0.231
LIG_deltaCOP1_diTrp_1	210	218	PF00928	0.311
LIG_deltaCOP1_diTrp_1	513	518	PF00928	0.270
LIG_DLG_GKlike_1	446	454	PF00625	0.481
LIG_FHA_1	106	112	PF00498	0.469
LIG_FHA_1	181	187	PF00498	0.228
LIG_FHA_1	235	241	PF00498	0.309
LIG_FHA_1	252	258	PF00498	0.261
LIG_FHA_1	329	335	PF00498	0.517
LIG_FHA_1	351	357	PF00498	0.502
LIG_FHA_1	445	451	PF00498	0.480
LIG_FHA_1	490	496	PF00498	0.375
LIG_FHA_1	501	507	PF00498	0.328
LIG_FHA_1	549	555	PF00498	0.424
LIG_FHA_2	267	273	PF00498	0.335
LIG_FHA_2	378	384	PF00498	0.387
LIG_FHA_2	510	516	PF00498	0.284
LIG_GSK3_LRP6_1	406	411	PF00069	0.518
LIG_LIR_Apic_2	359	365	PF02991	0.369
LIG_LIR_Apic_2	474	480	PF02991	0.464
LIG_LIR_Apic_2	49	55	PF02991	0.483
LIG_LIR_Gen_1	132	143	PF02991	0.291
LIG_LIR_Gen_1	327	338	PF02991	0.511
LIG_LIR_Gen_1	511	522	PF02991	0.266
LIG_LIR_Gen_1	538	547	PF02991	0.301
LIG_LIR_Nem_3	132	138	PF02991	0.280
LIG_LIR_Nem_3	16	22	PF02991	0.504
LIG_LIR_Nem_3	327	333	PF02991	0.506
LIG_LIR_Nem_3	366	372	PF02991	0.269
LIG_LIR_Nem_3	511	517	PF02991	0.276
LIG_LIR_Nem_3	538	543	PF02991	0.293
LIG_Pex14_1	369	373	PF04695	0.258
LIG_Pex14_1	514	518	PF04695	0.261
LIG_Pex14_2	295	299	PF04695	0.460
LIG_Pex14_2	370	374	PF04695	0.264
LIG_PTB_Apo_2	385	392	PF02174	0.489
LIG_RPA_C_Fungi	254	266	PF08784	0.246
LIG_SH2_CRK	362	366	PF00017	0.330
LIG_SH2_CRK	52	56	PF00017	0.478
LIG_SH2_NCK_1	52	56	PF00017	0.478
LIG_SH2_NCK_1	82	86	PF00017	0.421
LIG_SH2_STAP1	261	265	PF00017	0.232
LIG_SH2_STAT5	21	24	PF00017	0.509
LIG_SH2_STAT5	372	375	PF00017	0.269
LIG_SH3_3	404	410	PF00018	0.519
LIG_SH3_3	429	435	PF00018	0.506
LIG_SUMO_SIM_par_1	112	117	PF11976	0.406
LIG_SUMO_SIM_par_1	446	452	PF11976	0.479
LIG_TRAF2_1	89	92	PF00917	0.426
MOD_CDK_SPxxK_3	392	399	PF00069	0.523
MOD_CDK_SPxxK_3	406	413	PF00069	0.522
MOD_CK1_1	104	110	PF00069	0.474
MOD_CK1_1	196	202	PF00069	0.326
MOD_CK1_1	289	295	PF00069	0.469
MOD_CK1_1	36	42	PF00069	0.485
MOD_CK1_1	402	408	PF00069	0.526
MOD_CK1_1	430	436	PF00069	0.503
MOD_CK1_1	449	455	PF00069	0.482
MOD_CK1_1	463	469	PF00069	0.488
MOD_CK1_1	471	477	PF00069	0.471
MOD_CK1_1	509	515	PF00069	0.293
MOD_CK1_1	95	101	PF00069	0.462
MOD_CK2_1	266	272	PF00069	0.314
MOD_CK2_1	80	86	PF00069	0.432
MOD_GlcNHglycan	101	104	PF01048	0.474
MOD_GlcNHglycan	196	199	PF01048	0.345
MOD_GlcNHglycan	25	28	PF01048	0.484
MOD_GlcNHglycan	29	32	PF01048	0.497
MOD_GlcNHglycan	345	348	PF01048	0.530
MOD_GlcNHglycan	38	41	PF01048	0.480
MOD_GlcNHglycan	420	423	PF01048	0.504
MOD_GlcNHglycan	440	443	PF01048	0.492
MOD_GlcNHglycan	465	468	PF01048	0.484
MOD_GlcNHglycan	477	480	PF01048	0.458
MOD_GSK3_1	103	110	PF00069	0.473
MOD_GSK3_1	124	131	PF00069	0.338
MOD_GSK3_1	23	30	PF00069	0.492
MOD_GSK3_1	266	273	PF00069	0.326
MOD_GSK3_1	276	283	PF00069	0.484
MOD_GSK3_1	324	331	PF00069	0.499
MOD_GSK3_1	339	346	PF00069	0.517
MOD_GSK3_1	350	357	PF00069	0.504
MOD_GSK3_1	391	398	PF00069	0.520
MOD_GSK3_1	402	409	PF00069	0.526
MOD_GSK3_1	413	420	PF00069	0.512
MOD_GSK3_1	430	437	PF00069	0.505
MOD_GSK3_1	457	464	PF00069	0.502
MOD_GSK3_1	471	478	PF00069	0.471
MOD_GSK3_1	502	509	PF00069	0.314
MOD_GSK3_1	520	527	PF00069	0.265
MOD_GSK3_1	95	102	PF00069	0.462
MOD_N-GLC_1	276	281	PF02516	0.477
MOD_NEK2_1	1	6	PF00069	0.509
MOD_NEK2_1	101	106	PF00069	0.474
MOD_NEK2_1	175	180	PF00069	0.226
MOD_NEK2_1	286	291	PF00069	0.476
MOD_NEK2_1	376	381	PF00069	0.336
MOD_NEK2_1	391	396	PF00069	0.517
MOD_NEK2_1	444	449	PF00069	0.482
MOD_NEK2_1	46	51	PF00069	0.488
MOD_NEK2_1	475	480	PF00069	0.462
MOD_NEK2_1	506	511	PF00069	0.302
MOD_NEK2_1	517	522	PF00069	0.256
MOD_NEK2_1	535	540	PF00069	0.281
MOD_NEK2_1	65	70	PF00069	0.430
MOD_NEK2_1	90	95	PF00069	0.426
MOD_PIKK_1	124	130	PF00454	0.350
MOD_PIKK_1	213	219	PF00454	0.338
MOD_PIKK_1	341	347	PF00454	0.520
MOD_PIKK_1	389	395	PF00454	0.514
MOD_PIKK_1	399	405	PF00454	0.535
MOD_PIKK_1	480	486	PF00454	0.432
MOD_PIKK_1	524	530	PF00454	0.291
MOD_PIKK_1	548	554	PF00454	0.404
MOD_PIKK_1	65	71	PF00454	0.429
MOD_PIKK_1	80	86	PF00454	0.432
MOD_PK_1	33	39	PF00069	0.497
MOD_PKA_1	147	153	PF00069	0.290
MOD_PKA_1	23	29	PF00069	0.493
MOD_PKA_1	281	287	PF00069	0.494
MOD_PKA_1	80	86	PF00069	0.432
MOD_PKA_2	129	135	PF00069	0.300
MOD_PKA_2	147	153	PF00069	0.290
MOD_PKA_2	23	29	PF00069	0.493
MOD_PKA_2	234	240	PF00069	0.323
MOD_PKA_2	280	286	PF00069	0.495
MOD_PKA_2	417	423	PF00069	0.507
MOD_PKA_2	471	477	PF00069	0.471
MOD_PKA_2	80	86	PF00069	0.432
MOD_PKB_1	23	31	PF00069	0.492
MOD_Plk_1	328	334	PF00069	0.512
MOD_Plk_1	501	507	PF00069	0.328
MOD_Plk_4	159	165	PF00069	0.253
MOD_Plk_4	203	209	PF00069	0.274
MOD_Plk_4	446	452	PF00069	0.479
MOD_Plk_4	502	508	PF00069	0.315
MOD_ProDKin_1	339	345	PF00069	0.515
MOD_ProDKin_1	378	384	PF00069	0.387
MOD_ProDKin_1	386	392	PF00069	0.497
MOD_ProDKin_1	402	408	PF00069	0.526
MOD_ProDKin_1	461	467	PF00069	0.498
MOD_ProDKin_1	95	101	PF00069	0.462
TRG_DiLeu_BaEn_1	502	507	PF01217	0.319
TRG_ER_diArg_1	147	149	PF00400	0.285
TRG_ER_diArg_1	22	25	PF00400	0.504
TRG_ER_diArg_1	32	34	PF00400	0.509
TRG_ER_diArg_1	57	60	PF00400	0.485
TRG_ER_diArg_1	80	82	PF00400	0.451
TRG_Pf-PMV_PEXEL_1	147	151	PF00026	0.282
TRG_Pf-PMV_PEXEL_1	496	501	PF00026	0.366