LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HEL5_LEIBR
TriTrypDb:
LbrM.26.0090 , LBRM2903_260005900 *
Length:
77

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HEL5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HEL5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 26 30 PF00656 0.553
CLV_NRD_NRD_1 11 13 PF00675 0.594
CLV_NRD_NRD_1 33 35 PF00675 0.528
CLV_PCSK_FUR_1 9 13 PF00082 0.558
CLV_PCSK_KEX2_1 11 13 PF00082 0.571
CLV_PCSK_KEX2_1 16 18 PF00082 0.539
CLV_PCSK_KEX2_1 35 37 PF00082 0.674
CLV_PCSK_PC1ET2_1 11 13 PF00082 0.557
CLV_PCSK_PC1ET2_1 16 18 PF00082 0.530
CLV_PCSK_PC1ET2_1 35 37 PF00082 0.510
CLV_PCSK_PC7_1 12 18 PF00082 0.565
CLV_PCSK_SKI1_1 25 29 PF00082 0.564
CLV_PCSK_SKI1_1 39 43 PF00082 0.431
CLV_PCSK_SKI1_1 69 73 PF00082 0.529
DEG_APCC_DBOX_1 38 46 PF00400 0.617
DOC_MAPK_gen_1 11 20 PF00069 0.508
DOC_PP1_SILK_1 39 44 PF00149 0.585
DOC_USP7_MATH_1 58 62 PF00917 0.695
DOC_USP7_UBL2_3 49 53 PF12436 0.567
DOC_USP7_UBL2_3 7 11 PF12436 0.554
LIG_14-3-3_CanoR_1 17 27 PF00244 0.555
LIG_FHA_2 19 25 PF00498 0.545
LIG_SH3_3 42 48 PF00018 0.412
MOD_CK2_1 18 24 PF00069 0.495
MOD_Cter_Amidation 32 35 PF01082 0.567
MOD_GlcNHglycan 60 63 PF01048 0.629
MOD_GSK3_1 23 30 PF00069 0.561
MOD_NEK2_1 23 28 PF00069 0.498
MOD_PK_1 37 43 PF00069 0.557
MOD_PKA_1 12 18 PF00069 0.565
MOD_Plk_1 23 29 PF00069 0.551
MOD_Plk_1 37 43 PF00069 0.562
TRG_NLS_MonoCore_2 10 15 PF00514 0.570
TRG_NLS_MonoExtC_3 11 16 PF00514 0.548
TRG_NLS_MonoExtN_4 69 76 PF00514 0.613
TRG_NLS_MonoExtN_4 9 16 PF00514 0.550
TRG_Pf-PMV_PEXEL_1 25 29 PF00026 0.567

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3K4 Leptomonas seymouri 83% 100%
A0A0S4IJI0 Bodo saltans 59% 81%
A0A381MJV1 Leishmania infantum 88% 100%
A0A3Q8IBZ2 Leishmania donovani 88% 100%
C9ZS75 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 61% 81%
E9AXZ1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 100%
Q4Q9I1 Leishmania major 86% 100%
V5DR93 Trypanosoma cruzi 65% 80%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS