RAP domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4HEK6_LEIBR

TriTrypDb:

LbrM.25.2630 , LBRM2903_160010900

Length:

230

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HEK6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HEK6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	147	149	PF00675	0.592
CLV_PCSK_KEX2_1	147	149	PF00082	0.537
CLV_PCSK_KEX2_1	88	90	PF00082	0.549
CLV_PCSK_PC1ET2_1	147	149	PF00082	0.537
CLV_PCSK_PC1ET2_1	88	90	PF00082	0.549
CLV_PCSK_SKI1_1	194	198	PF00082	0.545
CLV_PCSK_SKI1_1	225	229	PF00082	0.501
CLV_PCSK_SKI1_1	38	42	PF00082	0.551
DEG_APCC_DBOX_1	37	45	PF00400	0.496
DEG_Nend_UBRbox_1	1	3	PF02207	0.562
DEG_SPOP_SBC_1	100	104	PF00917	0.602
DOC_CYCLIN_yCln2_LP_2	19	25	PF00134	0.563
DOC_MAPK_gen_1	36	43	PF00069	0.489
DOC_MAPK_MEF2A_6	17	26	PF00069	0.570
DOC_MAPK_MEF2A_6	36	43	PF00069	0.489
DOC_MAPK_NFAT4_5	36	44	PF00069	0.491
DOC_PP1_RVXF_1	86	93	PF00149	0.554
DOC_USP7_MATH_1	98	102	PF00917	0.599
LIG_14-3-3_CanoR_1	130	139	PF00244	0.596
LIG_14-3-3_CanoR_1	99	108	PF00244	0.608
LIG_14-3-3_CterR_2	225	230	PF00244	0.564
LIG_BRCT_BRCA1_1	185	189	PF00533	0.461
LIG_deltaCOP1_diTrp_1	84	92	PF00928	0.545
LIG_FHA_1	119	125	PF00498	0.594
LIG_FHA_1	14	20	PF00498	0.713
LIG_FHA_1	167	173	PF00498	0.570
LIG_FHA_2	101	107	PF00498	0.606
LIG_FHA_2	193	199	PF00498	0.686
LIG_LIR_Apic_2	133	138	PF02991	0.523
LIG_LIR_Gen_1	175	184	PF02991	0.685
LIG_LIR_Gen_1	195	204	PF02991	0.480
LIG_LIR_Gen_1	28	39	PF02991	0.665
LIG_LIR_Nem_3	159	164	PF02991	0.577
LIG_LIR_Nem_3	175	180	PF02991	0.446
LIG_LIR_Nem_3	195	200	PF02991	0.484
LIG_LIR_Nem_3	28	34	PF02991	0.519
LIG_PCNA_yPIPBox_3	36	44	PF02747	0.549
LIG_SH2_CRK	135	139	PF00017	0.529
LIG_SH2_GRB2like	135	138	PF00017	0.529
LIG_SH2_SRC	135	138	PF00017	0.529
LIG_SH2_STAT5	214	217	PF00017	0.542
LIG_SH3_3	40	46	PF00018	0.558
LIG_SH3_3	62	68	PF00018	0.590
LIG_SH3_3	92	98	PF00018	0.588
LIG_SUMO_SIM_par_1	162	169	PF11976	0.589
LIG_TRAF2_1	196	199	PF00917	0.541
LIG_ULM_U2AF65_1	146	151	PF00076	0.593
MOD_CK1_1	101	107	PF00069	0.606
MOD_CK1_1	165	171	PF00069	0.583
MOD_CK1_1	192	198	PF00069	0.548
MOD_CK1_1	202	208	PF00069	0.440
MOD_CK2_1	100	106	PF00069	0.700
MOD_CK2_1	192	198	PF00069	0.688
MOD_CK2_1	78	84	PF00069	0.556
MOD_CMANNOS	150	153	PF00535	0.568
MOD_GlcNHglycan	103	106	PF01048	0.630
MOD_GlcNHglycan	132	135	PF01048	0.625
MOD_GlcNHglycan	185	188	PF01048	0.463
MOD_GlcNHglycan	80	83	PF01048	0.548
MOD_GSK3_1	162	169	PF00069	0.729
MOD_N-GLC_2	62	64	PF02516	0.575
MOD_NEK2_1	108	113	PF00069	0.595
MOD_NEK2_1	166	171	PF00069	0.582
MOD_PKA_2	98	104	PF00069	0.541
MOD_Plk_1	108	114	PF00069	0.732
TRG_AP2beta_CARGO_1	28	38	PF09066	0.533
TRG_DiLeu_BaLyEn_6	35	40	PF01217	0.476
TRG_ER_diArg_1	35	38	PF00400	0.651
TRG_ER_diArg_1	8	11	PF00400	0.602
TRG_NLS_MonoCore_2	145	150	PF00514	0.599
TRG_NLS_MonoExtC_3	146	152	PF00514	0.586
TRG_NLS_MonoExtN_4	146	151	PF00514	0.593
TRG_Pf-PMV_PEXEL_1	17	21	PF00026	0.575
TRG_Pf-PMV_PEXEL_1	206	210	PF00026	0.517
TRG_Pf-PMV_PEXEL_1	225	230	PF00026	0.564
TRG_Pf-PMV_PEXEL_1	42	47	PF00026	0.499

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0NL69	Trypanosomatidae	31%	80%
A4H3G5	Leishmania braziliensis	95%	100%