ATPase beta subunit, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP synthase subunit beta, mitochondrial, putative (fragment)

Species:

Leishmania braziliensis

UniProt:

A4HEJ4_LEIBR

TriTrypDb:

LbrM.25.2510 , LBRM2903_250021100

Length:

213

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 10

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HEJ4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HEJ4

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	3
GO:0006163	purine nucleotide metabolic process	5	3
GO:0006725	cellular aromatic compound metabolic process	3	3
GO:0006753	nucleoside phosphate metabolic process	4	3
GO:0006793	phosphorus metabolic process	3	3
GO:0006796	phosphate-containing compound metabolic process	4	3
GO:0006807	nitrogen compound metabolic process	2	3
GO:0006810	transport	3	3
GO:0006811	monoatomic ion transport	4	3
GO:0006812	monoatomic cation transport	5	3
GO:0008152	metabolic process	1	3
GO:0009117	nucleotide metabolic process	5	3
GO:0009141	nucleoside triphosphate metabolic process	5	3
GO:0009144	purine nucleoside triphosphate metabolic process	6	3
GO:0009150	purine ribonucleotide metabolic process	6	3
GO:0009199	ribonucleoside triphosphate metabolic process	6	3
GO:0009205	purine ribonucleoside triphosphate metabolic process	7	3
GO:0009259	ribonucleotide metabolic process	5	3
GO:0009987	cellular process	1	3
GO:0019637	organophosphate metabolic process	3	3
GO:0019693	ribose phosphate metabolic process	4	3
GO:0034220	monoatomic ion transmembrane transport	3	3
GO:0034641	cellular nitrogen compound metabolic process	3	3
GO:0044237	cellular metabolic process	2	3
GO:0044238	primary metabolic process	2	3
GO:0044281	small molecule metabolic process	2	3
GO:0046034	ATP metabolic process	7	3
GO:0046483	heterocycle metabolic process	3	3
GO:0051179	localization	1	3
GO:0051234	establishment of localization	2	3
GO:0055085	transmembrane transport	2	3
GO:0055086	nucleobase-containing small molecule metabolic process	3	3
GO:0071704	organic substance metabolic process	2	3
GO:0072521	purine-containing compound metabolic process	4	3
GO:0098655	monoatomic cation transmembrane transport	4	3
GO:0098660	inorganic ion transmembrane transport	4	3
GO:0098662	inorganic cation transmembrane transport	5	3
GO:1901135	carbohydrate derivative metabolic process	3	3
GO:1901360	organic cyclic compound metabolic process	3	3
GO:1901564	organonitrogen compound metabolic process	3	3
GO:1902600	proton transmembrane transport	6	3

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	3
GO:0005488	binding	1	3
GO:0005524	ATP binding	5	3
GO:0017076	purine nucleotide binding	4	3
GO:0030554	adenyl nucleotide binding	5	3
GO:0032553	ribonucleotide binding	3	3
GO:0032555	purine ribonucleotide binding	4	3
GO:0032559	adenyl ribonucleotide binding	5	3
GO:0035639	purine ribonucleoside triphosphate binding	4	3
GO:0036094	small molecule binding	2	3
GO:0043167	ion binding	2	3
GO:0043168	anion binding	3	3
GO:0097159	organic cyclic compound binding	2	3
GO:0097367	carbohydrate derivative binding	2	3
GO:1901265	nucleoside phosphate binding	3	3
GO:1901363	heterocyclic compound binding	2	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	11	13	PF00675	0.560
CLV_PCSK_KEX2_1	11	13	PF00082	0.608
CLV_PCSK_SKI1_1	11	15	PF00082	0.589
DEG_APCC_DBOX_1	116	124	PF00400	0.369
DEG_Nend_Nbox_1	1	3	PF02207	0.625
DOC_MAPK_MEF2A_6	70	78	PF00069	0.282
DOC_PP2B_LxvP_1	171	174	PF13499	0.258
DOC_USP7_MATH_1	22	26	PF00917	0.564
DOC_USP7_UBL2_3	99	103	PF12436	0.282
LIG_14-3-3_CanoR_1	17	26	PF00244	0.722
LIG_APCC_ABBA_1	143	148	PF00400	0.400
LIG_APCC_ABBAyCdc20_2	142	148	PF00400	0.398
LIG_FHA_1	161	167	PF00498	0.339
LIG_FHA_1	190	196	PF00498	0.258
LIG_FHA_1	63	69	PF00498	0.282
LIG_FHA_1	73	79	PF00498	0.221
LIG_FHA_1	92	98	PF00498	0.282
LIG_FHA_2	58	64	PF00498	0.282
LIG_PDZ_Class_2	208	213	PF00595	0.354
LIG_SH2_STAT3	38	41	PF00017	0.282
LIG_SH2_STAT5	175	178	PF00017	0.337
LIG_SH2_STAT5	38	41	PF00017	0.282
LIG_SH3_3	23	29	PF00018	0.561
LIG_SUMO_SIM_anti_2	192	197	PF11976	0.258
LIG_SUMO_SIM_anti_2	75	80	PF11976	0.282
LIG_SUMO_SIM_par_1	191	197	PF11976	0.258
LIG_SUMO_SIM_par_1	71	77	PF11976	0.282
LIG_UBA3_1	195	204	PF00899	0.258
LIG_UBA3_1	97	103	PF00899	0.282
MOD_GlcNHglycan	19	22	PF01048	0.707
MOD_GlcNHglycan	6	9	PF01048	0.603
MOD_GSK3_1	157	164	PF00069	0.371
MOD_GSK3_1	99	106	PF00069	0.515
MOD_N-GLC_1	109	114	PF02516	0.356
MOD_NEK2_2	207	212	PF00069	0.381
MOD_PIKK_1	37	43	PF00454	0.282
MOD_PKA_1	11	17	PF00069	0.613
MOD_PKA_2	11	17	PF00069	0.543
MOD_PKA_2	116	122	PF00069	0.369
MOD_Plk_1	109	115	PF00069	0.356
MOD_Plk_1	157	163	PF00069	0.383
MOD_Plk_2-3	72	78	PF00069	0.282
MOD_Plk_4	157	163	PF00069	0.383
MOD_Plk_4	189	195	PF00069	0.258
TRG_ER_diArg_1	10	12	PF00400	0.568

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4I1G0	Leishmania infantum	94%	79%
Q24751	Drosophila virilis	61%	93%