LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HEI8_LEIBR
TriTrypDb:
LbrM.25.2450 , LBRM2903_250027200
Length:
874

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HEI8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HEI8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 30 34 PF00656 0.870
CLV_NRD_NRD_1 777 779 PF00675 0.856
CLV_NRD_NRD_1 804 806 PF00675 0.869
CLV_PCSK_KEX2_1 806 808 PF00082 0.865
CLV_PCSK_PC1ET2_1 806 808 PF00082 0.865
CLV_PCSK_SKI1_1 92 96 PF00082 0.854
DEG_Nend_Nbox_1 1 3 PF02207 0.864
DEG_SPOP_SBC_1 16 20 PF00917 0.854
DOC_PP1_SILK_1 98 103 PF00149 0.835
DOC_USP7_MATH_1 155 159 PF00917 0.849
DOC_USP7_MATH_1 294 298 PF00917 0.855
DOC_USP7_MATH_1 34 38 PF00917 0.879
DOC_USP7_MATH_1 490 494 PF00917 0.864
DOC_USP7_MATH_1 686 690 PF00917 0.866
DOC_USP7_MATH_1 765 769 PF00917 0.867
DOC_USP7_MATH_1 822 826 PF00917 0.874
DOC_USP7_MATH_1 834 838 PF00917 0.657
DOC_USP7_MATH_1 843 847 PF00917 0.710
DOC_USP7_UBL2_3 328 332 PF12436 0.860
DOC_USP7_UBL2_3 524 528 PF12436 0.869
DOC_USP7_UBL2_3 720 724 PF12436 0.871
DOC_WW_Pin1_4 280 285 PF00397 0.879
DOC_WW_Pin1_4 307 312 PF00397 0.860
DOC_WW_Pin1_4 476 481 PF00397 0.868
DOC_WW_Pin1_4 503 508 PF00397 0.870
DOC_WW_Pin1_4 672 677 PF00397 0.876
DOC_WW_Pin1_4 699 704 PF00397 0.870
DOC_WW_Pin1_4 769 774 PF00397 0.854
DOC_WW_Pin1_4 793 798 PF00397 0.876
DOC_WW_Pin1_4 820 825 PF00397 0.871
DOC_WW_Pin1_4 837 842 PF00397 0.563
LIG_14-3-3_CanoR_1 115 120 PF00244 0.793
LIG_Actin_WH2_2 87 104 PF00022 0.850
LIG_BIR_III_2 84 88 PF00653 0.876
LIG_BRCT_BRCA1_1 103 107 PF00533 0.823
LIG_FHA_1 316 322 PF00498 0.875
LIG_FHA_1 4 10 PF00498 0.848
LIG_FHA_1 512 518 PF00498 0.875
LIG_FHA_1 708 714 PF00498 0.889
LIG_FHA_1 764 770 PF00498 0.868
LIG_FHA_1 834 840 PF00498 0.867
LIG_FHA_1 854 860 PF00498 0.520
LIG_FHA_2 203 209 PF00498 0.870
LIG_FHA_2 320 326 PF00498 0.871
LIG_FHA_2 399 405 PF00498 0.871
LIG_FHA_2 516 522 PF00498 0.876
LIG_FHA_2 595 601 PF00498 0.873
LIG_FHA_2 61 67 PF00498 0.873
LIG_FHA_2 712 718 PF00498 0.882
LIG_FHA_2 864 870 PF00498 0.851
LIG_HCF-1_HBM_1 12 15 PF13415 0.859
LIG_Pex14_2 220 224 PF04695 0.862
LIG_Pex14_2 416 420 PF04695 0.861
LIG_Pex14_2 612 616 PF04695 0.859
LIG_SH2_GRB2like 38 41 PF00017 0.873
LIG_SH2_STAP1 867 871 PF00017 0.842
LIG_SH2_STAT5 15 18 PF00017 0.858
LIG_SH2_STAT5 150 153 PF00017 0.841
LIG_SH2_STAT5 181 184 PF00017 0.859
LIG_SH2_STAT5 247 250 PF00017 0.882
LIG_SH2_STAT5 377 380 PF00017 0.853
LIG_SH2_STAT5 443 446 PF00017 0.870
LIG_SH2_STAT5 573 576 PF00017 0.852
LIG_SH2_STAT5 639 642 PF00017 0.890
LIG_SH3_3 234 240 PF00018 0.876
LIG_SH3_3 430 436 PF00018 0.877
LIG_SH3_3 54 60 PF00018 0.866
LIG_SH3_3 626 632 PF00018 0.885
LIG_SH3_3 816 822 PF00018 0.874
LIG_SH3_4 328 335 PF00018 0.864
LIG_SH3_4 524 531 PF00018 0.871
LIG_SH3_4 720 727 PF00018 0.873
LIG_SUMO_SIM_anti_2 295 300 PF11976 0.860
LIG_SUMO_SIM_anti_2 491 496 PF11976 0.870
LIG_SUMO_SIM_anti_2 687 692 PF11976 0.871
LIG_TRAF2_1 184 187 PF00917 0.850
LIG_TRAF2_1 205 208 PF00917 0.873
LIG_TRAF2_1 270 273 PF00917 0.881
LIG_TRAF2_1 344 347 PF00917 0.871
LIG_TRAF2_1 380 383 PF00917 0.855
LIG_TRAF2_1 401 404 PF00917 0.871
LIG_TRAF2_1 466 469 PF00917 0.862
LIG_TRAF2_1 540 543 PF00917 0.876
LIG_TRAF2_1 576 579 PF00917 0.859
LIG_TRAF2_1 597 600 PF00917 0.871
LIG_TRAF2_1 63 66 PF00917 0.873
LIG_TRAF2_1 662 665 PF00917 0.878
LIG_TRAF2_1 736 739 PF00917 0.874
LIG_TRAF2_1 783 786 PF00917 0.845
MOD_CDC14_SPxK_1 283 286 PF00782 0.882
MOD_CDC14_SPxK_1 479 482 PF00782 0.873
MOD_CDC14_SPxK_1 675 678 PF00782 0.884
MOD_CDC14_SPxK_1 796 799 PF00782 0.880
MOD_CDK_SPK_2 280 285 PF00069 0.879
MOD_CDK_SPK_2 476 481 PF00069 0.868
MOD_CDK_SPK_2 672 677 PF00069 0.876
MOD_CDK_SPxK_1 280 286 PF00069 0.880
MOD_CDK_SPxK_1 476 482 PF00069 0.870
MOD_CDK_SPxK_1 672 678 PF00069 0.878
MOD_CDK_SPxK_1 793 799 PF00069 0.880
MOD_CK1_1 103 109 PF00069 0.701
MOD_CK1_1 110 116 PF00069 0.567
MOD_CK1_1 18 24 PF00069 0.857
MOD_CK1_1 223 229 PF00069 0.862
MOD_CK1_1 27 33 PF00069 0.708
MOD_CK1_1 288 294 PF00069 0.860
MOD_CK1_1 36 42 PF00069 0.557
MOD_CK1_1 369 375 PF00069 0.861
MOD_CK1_1 419 425 PF00069 0.866
MOD_CK1_1 484 490 PF00069 0.857
MOD_CK1_1 565 571 PF00069 0.856
MOD_CK1_1 615 621 PF00069 0.870
MOD_CK1_1 680 686 PF00069 0.868
MOD_CK1_1 760 766 PF00069 0.876
MOD_CK1_1 810 816 PF00069 0.882
MOD_CK1_1 823 829 PF00069 0.651
MOD_CK1_1 837 843 PF00069 0.616
MOD_CK1_1 96 102 PF00069 0.841
MOD_CK2_1 202 208 PF00069 0.864
MOD_CK2_1 267 273 PF00069 0.880
MOD_CK2_1 294 300 PF00069 0.859
MOD_CK2_1 319 325 PF00069 0.871
MOD_CK2_1 335 341 PF00069 0.597
MOD_CK2_1 398 404 PF00069 0.866
MOD_CK2_1 463 469 PF00069 0.868
MOD_CK2_1 490 496 PF00069 0.867
MOD_CK2_1 515 521 PF00069 0.876
MOD_CK2_1 531 537 PF00069 0.602
MOD_CK2_1 594 600 PF00069 0.871
MOD_CK2_1 60 66 PF00069 0.872
MOD_CK2_1 659 665 PF00069 0.877
MOD_CK2_1 686 692 PF00069 0.869
MOD_CK2_1 711 717 PF00069 0.882
MOD_CK2_1 727 733 PF00069 0.604
MOD_CK2_1 824 830 PF00069 0.878
MOD_GlcNHglycan 175 178 PF01048 0.871
MOD_GlcNHglycan 20 23 PF01048 0.854
MOD_GlcNHglycan 26 29 PF01048 0.761
MOD_GlcNHglycan 267 270 PF01048 0.881
MOD_GlcNHglycan 336 340 PF01048 0.877
MOD_GlcNHglycan 371 374 PF01048 0.859
MOD_GlcNHglycan 463 466 PF01048 0.871
MOD_GlcNHglycan 532 536 PF01048 0.882
MOD_GlcNHglycan 567 570 PF01048 0.856
MOD_GlcNHglycan 659 662 PF01048 0.878
MOD_GlcNHglycan 728 732 PF01048 0.884
MOD_GlcNHglycan 763 766 PF01048 0.873
MOD_GlcNHglycan 814 817 PF01048 0.887
MOD_GlcNHglycan 836 839 PF01048 0.866
MOD_GlcNHglycan 849 852 PF01048 0.648
MOD_GlcNHglycan 860 863 PF01048 0.679
MOD_GSK3_1 101 108 PF00069 0.668
MOD_GSK3_1 110 117 PF00069 0.491
MOD_GSK3_1 14 21 PF00069 0.855
MOD_GSK3_1 168 175 PF00069 0.860
MOD_GSK3_1 285 292 PF00069 0.870
MOD_GSK3_1 29 36 PF00069 0.610
MOD_GSK3_1 315 322 PF00069 0.876
MOD_GSK3_1 364 371 PF00069 0.867
MOD_GSK3_1 481 488 PF00069 0.868
MOD_GSK3_1 511 518 PF00069 0.876
MOD_GSK3_1 560 567 PF00069 0.864
MOD_GSK3_1 677 684 PF00069 0.877
MOD_GSK3_1 707 714 PF00069 0.889
MOD_GSK3_1 756 763 PF00069 0.875
MOD_GSK3_1 765 772 PF00069 0.706
MOD_GSK3_1 807 814 PF00069 0.877
MOD_GSK3_1 820 827 PF00069 0.644
MOD_GSK3_1 830 837 PF00069 0.698
MOD_GSK3_1 843 850 PF00069 0.642
MOD_GSK3_1 92 99 PF00069 0.851
MOD_N-GLC_1 166 171 PF02516 0.859
MOD_N-GLC_1 289 294 PF02516 0.859
MOD_N-GLC_1 485 490 PF02516 0.855
MOD_N-GLC_1 681 686 PF02516 0.868
MOD_N-GLC_1 760 765 PF02516 0.876
MOD_N-GLC_1 863 868 PF02516 0.857
MOD_NEK2_1 101 106 PF00069 0.828
MOD_NEK2_1 107 112 PF00069 0.713
MOD_NEK2_1 168 173 PF00069 0.858
MOD_NEK2_1 220 225 PF00069 0.861
MOD_NEK2_1 366 371 PF00069 0.863
MOD_NEK2_1 416 421 PF00069 0.863
MOD_NEK2_1 562 567 PF00069 0.861
MOD_NEK2_1 612 617 PF00069 0.862
MOD_NEK2_1 811 816 PF00069 0.884
MOD_PIKK_1 166 172 PF00454 0.860
MOD_PIKK_1 341 347 PF00454 0.873
MOD_PIKK_1 537 543 PF00454 0.877
MOD_PIKK_1 733 739 PF00454 0.879
MOD_PKA_1 285 291 PF00069 0.873
MOD_PKA_1 481 487 PF00069 0.873
MOD_PKA_1 677 683 PF00069 0.881
MOD_PKA_2 114 120 PF00069 0.480
MOD_PKA_2 3 9 PF00069 0.853
MOD_PKA_2 96 102 PF00069 0.841
MOD_PKB_1 805 813 PF00069 0.875
MOD_Plk_1 155 161 PF00069 0.852
MOD_Plk_1 220 226 PF00069 0.861
MOD_Plk_1 294 300 PF00069 0.859
MOD_Plk_1 416 422 PF00069 0.862
MOD_Plk_1 490 496 PF00069 0.867
MOD_Plk_1 612 618 PF00069 0.863
MOD_Plk_1 66 72 PF00069 0.867
MOD_Plk_1 686 692 PF00069 0.869
MOD_Plk_1 807 813 PF00069 0.876
MOD_Plk_1 863 869 PF00069 0.856
MOD_Plk_2-3 260 266 PF00069 0.871
MOD_Plk_2-3 456 462 PF00069 0.870
MOD_Plk_2-3 652 658 PF00069 0.874
MOD_Plk_2-3 66 72 PF00069 0.867
MOD_Plk_4 294 300 PF00069 0.859
MOD_Plk_4 490 496 PF00069 0.867
MOD_Plk_4 686 692 PF00069 0.869
MOD_Plk_4 807 813 PF00069 0.876
MOD_Plk_4 96 102 PF00069 0.841
MOD_ProDKin_1 280 286 PF00069 0.880
MOD_ProDKin_1 307 313 PF00069 0.862
MOD_ProDKin_1 476 482 PF00069 0.870
MOD_ProDKin_1 503 509 PF00069 0.872
MOD_ProDKin_1 672 678 PF00069 0.878
MOD_ProDKin_1 699 705 PF00069 0.873
MOD_ProDKin_1 769 775 PF00069 0.855
MOD_ProDKin_1 793 799 PF00069 0.880
MOD_ProDKin_1 820 826 PF00069 0.871
MOD_ProDKin_1 837 843 PF00069 0.564
MOD_SUMO_for_1 131 134 PF00179 0.738
MOD_SUMO_for_1 783 786 PF00179 0.845
MOD_SUMO_rev_2 186 191 PF00179 0.856
MOD_SUMO_rev_2 260 268 PF00179 0.871
MOD_SUMO_rev_2 325 330 PF00179 0.865
MOD_SUMO_rev_2 382 387 PF00179 0.866
MOD_SUMO_rev_2 456 464 PF00179 0.872
MOD_SUMO_rev_2 521 526 PF00179 0.868
MOD_SUMO_rev_2 578 583 PF00179 0.865
MOD_SUMO_rev_2 64 69 PF00179 0.872
MOD_SUMO_rev_2 652 660 PF00179 0.875
MOD_SUMO_rev_2 717 722 PF00179 0.874

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS