LeishMANIAdb
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ATP synthase subunit e, mitochondrial

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
ATP synthase subunit e, mitochondrial
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HEF9_LEIBR
TriTrypDb:
LbrM.25.2160 , LBRM2903_250012800 *
Length:
98

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 18
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 1, no: 8
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HEF9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HEF9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 38 42 PF00656 0.421
DEG_Nend_Nbox_1 1 3 PF02207 0.473
DOC_USP7_UBL2_3 8 12 PF12436 0.548
DOC_USP7_UBL2_3 91 95 PF12436 0.583
LIG_14-3-3_CanoR_1 18 23 PF00244 0.548
LIG_FHA_1 4 10 PF00498 0.536
LIG_LIR_Gen_1 21 30 PF02991 0.542
LIG_LIR_Nem_3 21 25 PF02991 0.541
LIG_Pex14_2 30 34 PF04695 0.516
LIG_SH2_CRK 22 26 PF00017 0.327
LIG_TYR_ITIM 20 25 PF00017 0.327
MOD_GlcNHglycan 36 40 PF01048 0.353
MOD_N-GLC_1 18 23 PF02516 0.521
MOD_N-GLC_2 15 17 PF02516 0.362
MOD_NEK2_1 1 6 PF00069 0.655
MOD_NEK2_1 74 79 PF00069 0.640
MOD_Plk_1 18 24 PF00069 0.546
MOD_Plk_1 74 80 PF00069 0.630
MOD_Plk_4 18 24 PF00069 0.331
TRG_ENDOCYTIC_2 22 25 PF00928 0.543
TRG_ENDOCYTIC_2 90 93 PF00928 0.576

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IL82 Leptomonas seymouri 80% 99%
A0A0S4ITT9 Bodo saltans 36% 96%
A0A3S7WYZ3 Leishmania donovani 81% 99%
A0A422NXB3 Trypanosoma rangeli 51% 78%
A4I1A0 Leishmania infantum 81% 99%
D0A5J1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 51% 92%
E9AXD6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 80% 99%
V5BNA9 Trypanosoma cruzi 57% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS