LeishMANIAdb
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DNA-directed RNA polymerase subunit beta

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
DNA-directed RNA polymerase subunit beta
Gene product:
RNA polymerase I second largest subunit, putative
Species:
Leishmania braziliensis
UniProt:
A4HEF6_LEIBR
TriTrypDb:
LbrM.25.2130 , LBRM2903_250013200 * , LBRM2903_250013300 *
Length:
1567

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0000428 DNA-directed RNA polymerase complex 4 12
GO:0005634 nucleus 5 11
GO:0030880 RNA polymerase complex 3 12
GO:0032991 protein-containing complex 1 12
GO:0043226 organelle 2 12
GO:0043227 membrane-bounded organelle 3 11
GO:0043229 intracellular organelle 3 12
GO:0043231 intracellular membrane-bounded organelle 4 11
GO:0061695 transferase complex, transferring phosphorus-containing groups 4 12
GO:0110165 cellular anatomical entity 1 12
GO:0140535 intracellular protein-containing complex 2 12
GO:1902494 catalytic complex 2 12
GO:1990234 transferase complex 3 12
GO:0005654 nucleoplasm 2 1
GO:0005730 nucleolus 5 1
GO:0005736 RNA polymerase I complex 4 1
GO:0043228 non-membrane-bounded organelle 3 1
GO:0043232 intracellular non-membrane-bounded organelle 4 1
GO:0055029 nuclear DNA-directed RNA polymerase complex 3 1
GO:0140513 nuclear protein-containing complex 2 1

Expansion

Sequence features

A4HEF6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 12
GO:0006351 DNA-templated transcription 7 12
GO:0006725 cellular aromatic compound metabolic process 3 12
GO:0006807 nitrogen compound metabolic process 2 12
GO:0008152 metabolic process 1 12
GO:0009058 biosynthetic process 2 12
GO:0009059 macromolecule biosynthetic process 4 12
GO:0009987 cellular process 1 12
GO:0016070 RNA metabolic process 5 12
GO:0018130 heterocycle biosynthetic process 4 12
GO:0019438 aromatic compound biosynthetic process 4 12
GO:0032774 RNA biosynthetic process 5 12
GO:0034641 cellular nitrogen compound metabolic process 3 12
GO:0034654 nucleobase-containing compound biosynthetic process 4 12
GO:0043170 macromolecule metabolic process 3 12
GO:0044237 cellular metabolic process 2 12
GO:0044238 primary metabolic process 2 12
GO:0044249 cellular biosynthetic process 3 12
GO:0044271 cellular nitrogen compound biosynthetic process 4 12
GO:0046483 heterocycle metabolic process 3 12
GO:0071704 organic substance metabolic process 2 12
GO:0090304 nucleic acid metabolic process 4 12
GO:0097659 nucleic acid-templated transcription 6 12
GO:1901360 organic cyclic compound metabolic process 3 12
GO:1901362 organic cyclic compound biosynthetic process 4 12
GO:1901576 organic substance biosynthetic process 3 12
Molecular functions
Term Name Level Count
GO:0001882 nucleoside binding 3 12
GO:0003676 nucleic acid binding 3 12
GO:0003677 DNA binding 4 12
GO:0003824 catalytic activity 1 12
GO:0003899 DNA-directed 5'-3' RNA polymerase activity 6 12
GO:0005488 binding 1 12
GO:0016740 transferase activity 2 12
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 12
GO:0016779 nucleotidyltransferase activity 4 12
GO:0032549 ribonucleoside binding 4 12
GO:0034062 5'-3' RNA polymerase activity 5 12
GO:0036094 small molecule binding 2 12
GO:0097159 organic cyclic compound binding 2 12
GO:0097367 carbohydrate derivative binding 2 12
GO:0097747 RNA polymerase activity 4 12
GO:0140098 catalytic activity, acting on RNA 3 12
GO:0140640 catalytic activity, acting on a nucleic acid 2 12
GO:1901363 heterocyclic compound binding 2 12

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1528 1532 PF00656 0.533
CLV_NRD_NRD_1 1041 1043 PF00675 0.448
CLV_NRD_NRD_1 1093 1095 PF00675 0.247
CLV_NRD_NRD_1 1454 1456 PF00675 0.247
CLV_NRD_NRD_1 258 260 PF00675 0.474
CLV_NRD_NRD_1 339 341 PF00675 0.440
CLV_NRD_NRD_1 47 49 PF00675 0.416
CLV_NRD_NRD_1 528 530 PF00675 0.247
CLV_NRD_NRD_1 634 636 PF00675 0.247
CLV_NRD_NRD_1 673 675 PF00675 0.308
CLV_NRD_NRD_1 783 785 PF00675 0.434
CLV_NRD_NRD_1 840 842 PF00675 0.248
CLV_NRD_NRD_1 957 959 PF00675 0.254
CLV_PCSK_FUR_1 502 506 PF00082 0.247
CLV_PCSK_KEX2_1 1204 1206 PF00082 0.247
CLV_PCSK_KEX2_1 1235 1237 PF00082 0.258
CLV_PCSK_KEX2_1 1456 1458 PF00082 0.247
CLV_PCSK_KEX2_1 258 260 PF00082 0.466
CLV_PCSK_KEX2_1 339 341 PF00082 0.440
CLV_PCSK_KEX2_1 504 506 PF00082 0.247
CLV_PCSK_KEX2_1 634 636 PF00082 0.247
CLV_PCSK_KEX2_1 783 785 PF00082 0.352
CLV_PCSK_KEX2_1 957 959 PF00082 0.253
CLV_PCSK_PC1ET2_1 1204 1206 PF00082 0.258
CLV_PCSK_PC1ET2_1 1235 1237 PF00082 0.258
CLV_PCSK_PC1ET2_1 1456 1458 PF00082 0.247
CLV_PCSK_PC1ET2_1 504 506 PF00082 0.247
CLV_PCSK_SKI1_1 1072 1076 PF00082 0.247
CLV_PCSK_SKI1_1 1095 1099 PF00082 0.247
CLV_PCSK_SKI1_1 1154 1158 PF00082 0.275
CLV_PCSK_SKI1_1 1165 1169 PF00082 0.210
CLV_PCSK_SKI1_1 1443 1447 PF00082 0.247
CLV_PCSK_SKI1_1 1508 1512 PF00082 0.258
CLV_PCSK_SKI1_1 1555 1559 PF00082 0.258
CLV_PCSK_SKI1_1 259 263 PF00082 0.474
CLV_PCSK_SKI1_1 433 437 PF00082 0.272
CLV_PCSK_SKI1_1 469 473 PF00082 0.256
CLV_PCSK_SKI1_1 486 490 PF00082 0.269
CLV_PCSK_SKI1_1 556 560 PF00082 0.252
CLV_PCSK_SKI1_1 587 591 PF00082 0.268
CLV_PCSK_SKI1_1 635 639 PF00082 0.250
CLV_PCSK_SKI1_1 783 787 PF00082 0.362
CLV_PCSK_SKI1_1 939 943 PF00082 0.250
CLV_Separin_Metazoa 88 92 PF03568 0.586
DEG_APCC_DBOX_1 432 440 PF00400 0.458
DEG_APCC_DBOX_1 47 55 PF00400 0.402
DEG_APCC_DBOX_1 634 642 PF00400 0.447
DEG_Nend_UBRbox_1 1 4 PF02207 0.345
DEG_SPOP_SBC_1 1322 1326 PF00917 0.371
DOC_CKS1_1 332 337 PF01111 0.440
DOC_CKS1_1 61 66 PF01111 0.565
DOC_CYCLIN_RxL_1 681 691 PF00134 0.533
DOC_CYCLIN_RxL_1 741 750 PF00134 0.467
DOC_CYCLIN_RxL_1 780 788 PF00134 0.356
DOC_CYCLIN_RxL_1 939 948 PF00134 0.474
DOC_CYCLIN_yCln2_LP_2 1009 1015 PF00134 0.346
DOC_CYCLIN_yCln2_LP_2 535 541 PF00134 0.533
DOC_CYCLIN_yCln2_LP_2 991 997 PF00134 0.401
DOC_MAPK_DCC_7 46 56 PF00069 0.255
DOC_MAPK_gen_1 1453 1463 PF00069 0.447
DOC_MAPK_gen_1 46 56 PF00069 0.502
DOC_MAPK_gen_1 529 537 PF00069 0.425
DOC_MAPK_gen_1 674 682 PF00069 0.508
DOC_MAPK_MEF2A_6 1309 1316 PF00069 0.458
DOC_MAPK_MEF2A_6 1343 1352 PF00069 0.513
DOC_MAPK_MEF2A_6 475 482 PF00069 0.438
DOC_MAPK_MEF2A_6 48 56 PF00069 0.260
DOC_MAPK_MEF2A_6 530 539 PF00069 0.418
DOC_MAPK_NFAT4_5 1309 1317 PF00069 0.458
DOC_PP1_RVXF_1 350 356 PF00149 0.406
DOC_PP1_RVXF_1 51 57 PF00149 0.546
DOC_PP1_RVXF_1 527 534 PF00149 0.447
DOC_PP2B_LxvP_1 535 538 PF13499 0.533
DOC_PP4_FxxP_1 1290 1293 PF00568 0.453
DOC_PP4_FxxP_1 1494 1497 PF00568 0.533
DOC_PP4_FxxP_1 175 178 PF00568 0.336
DOC_PP4_FxxP_1 332 335 PF00568 0.397
DOC_PP4_FxxP_1 799 802 PF00568 0.351
DOC_USP7_MATH_1 1028 1032 PF00917 0.451
DOC_USP7_MATH_1 1339 1343 PF00917 0.413
DOC_USP7_MATH_1 1526 1530 PF00917 0.533
DOC_USP7_MATH_1 206 210 PF00917 0.464
DOC_USP7_MATH_1 36 40 PF00917 0.413
DOC_USP7_MATH_1 368 372 PF00917 0.582
DOC_USP7_MATH_1 377 381 PF00917 0.515
DOC_USP7_MATH_1 563 567 PF00917 0.371
DOC_USP7_MATH_1 617 621 PF00917 0.524
DOC_USP7_MATH_1 802 806 PF00917 0.354
DOC_USP7_MATH_1 901 905 PF00917 0.452
DOC_USP7_MATH_1 94 98 PF00917 0.542
DOC_USP7_MATH_2 130 136 PF00917 0.472
DOC_WW_Pin1_4 1067 1072 PF00397 0.447
DOC_WW_Pin1_4 1327 1332 PF00397 0.447
DOC_WW_Pin1_4 185 190 PF00397 0.484
DOC_WW_Pin1_4 331 336 PF00397 0.397
DOC_WW_Pin1_4 60 65 PF00397 0.545
DOC_WW_Pin1_4 645 650 PF00397 0.452
DOC_WW_Pin1_4 662 667 PF00397 0.400
DOC_WW_Pin1_4 853 858 PF00397 0.447
DOC_WW_Pin1_4 874 879 PF00397 0.484
DOC_WW_Pin1_4 924 929 PF00397 0.488
DOC_WW_Pin1_4 959 964 PF00397 0.533
LIG_14-3-3_CanoR_1 1003 1013 PF00244 0.235
LIG_14-3-3_CanoR_1 1154 1163 PF00244 0.533
LIG_14-3-3_CanoR_1 1205 1211 PF00244 0.533
LIG_14-3-3_CanoR_1 1343 1347 PF00244 0.447
LIG_14-3-3_CanoR_1 1434 1442 PF00244 0.508
LIG_14-3-3_CanoR_1 1508 1516 PF00244 0.458
LIG_14-3-3_CanoR_1 205 214 PF00244 0.454
LIG_14-3-3_CanoR_1 267 271 PF00244 0.398
LIG_14-3-3_CanoR_1 292 300 PF00244 0.307
LIG_14-3-3_CanoR_1 385 395 PF00244 0.459
LIG_14-3-3_CanoR_1 486 494 PF00244 0.375
LIG_14-3-3_CanoR_1 587 596 PF00244 0.510
LIG_14-3-3_CanoR_1 744 749 PF00244 0.439
LIG_14-3-3_CanoR_1 80 90 PF00244 0.502
LIG_14-3-3_CanoR_1 836 844 PF00244 0.447
LIG_14-3-3_CanoR_1 900 910 PF00244 0.442
LIG_Actin_WH2_2 1545 1561 PF00022 0.472
LIG_Actin_WH2_2 296 312 PF00022 0.410
LIG_Actin_WH2_2 422 439 PF00022 0.447
LIG_Actin_WH2_2 5 22 PF00022 0.558
LIG_AP2alpha_2 1241 1243 PF02296 0.533
LIG_APCC_ABBA_1 146 151 PF00400 0.190
LIG_APCC_ABBA_1 40 45 PF00400 0.363
LIG_APCC_ABBA_1 480 485 PF00400 0.458
LIG_APCC_ABBA_1 686 691 PF00400 0.533
LIG_APCC_ABBA_1 982 987 PF00400 0.458
LIG_BIR_III_2 960 964 PF00653 0.533
LIG_BRCT_BRCA1_1 606 610 PF00533 0.447
LIG_deltaCOP1_diTrp_1 416 425 PF00928 0.335
LIG_deltaCOP1_diTrp_1 625 631 PF00928 0.447
LIG_DLG_GKlike_1 1498 1505 PF00625 0.552
LIG_DLG_GKlike_1 744 751 PF00625 0.413
LIG_eIF4E_1 1395 1401 PF01652 0.458
LIG_eIF4E_1 986 992 PF01652 0.468
LIG_FHA_1 1050 1056 PF00498 0.507
LIG_FHA_1 1156 1162 PF00498 0.508
LIG_FHA_1 1191 1197 PF00498 0.447
LIG_FHA_1 1282 1288 PF00498 0.447
LIG_FHA_1 1309 1315 PF00498 0.457
LIG_FHA_1 1324 1330 PF00498 0.427
LIG_FHA_1 1352 1358 PF00498 0.533
LIG_FHA_1 1528 1534 PF00498 0.458
LIG_FHA_1 174 180 PF00498 0.499
LIG_FHA_1 27 33 PF00498 0.517
LIG_FHA_1 304 310 PF00498 0.496
LIG_FHA_1 544 550 PF00498 0.517
LIG_FHA_1 588 594 PF00498 0.477
LIG_FHA_1 646 652 PF00498 0.447
LIG_FHA_1 681 687 PF00498 0.533
LIG_FHA_1 786 792 PF00498 0.408
LIG_FHA_1 881 887 PF00498 0.528
LIG_FHA_1 911 917 PF00498 0.351
LIG_FHA_1 964 970 PF00498 0.481
LIG_FHA_2 1135 1141 PF00498 0.447
LIG_FHA_2 1295 1301 PF00498 0.508
LIG_FHA_2 1370 1376 PF00498 0.520
LIG_FHA_2 2 8 PF00498 0.501
LIG_FHA_2 279 285 PF00498 0.546
LIG_FHA_2 361 367 PF00498 0.525
LIG_FHA_2 517 523 PF00498 0.447
LIG_FHA_2 829 835 PF00498 0.472
LIG_FHA_2 83 89 PF00498 0.537
LIG_GBD_Chelix_1 1379 1387 PF00786 0.333
LIG_HCF-1_HBM_1 1218 1221 PF13415 0.447
LIG_IRF3_LxIS_1 1312 1317 PF10401 0.371
LIG_IRF3_LxIS_1 864 871 PF10401 0.425
LIG_LIR_Apic_2 1491 1497 PF02991 0.533
LIG_LIR_Apic_2 343 348 PF02991 0.396
LIG_LIR_Apic_2 407 413 PF02991 0.457
LIG_LIR_Apic_2 796 802 PF02991 0.355
LIG_LIR_Apic_2 968 974 PF02991 0.458
LIG_LIR_Gen_1 1020 1030 PF02991 0.357
LIG_LIR_Gen_1 1052 1062 PF02991 0.415
LIG_LIR_Gen_1 1368 1377 PF02991 0.447
LIG_LIR_Gen_1 151 161 PF02991 0.328
LIG_LIR_Gen_1 260 268 PF02991 0.421
LIG_LIR_Gen_1 389 400 PF02991 0.361
LIG_LIR_Gen_1 406 413 PF02991 0.155
LIG_LIR_Gen_1 416 426 PF02991 0.291
LIG_LIR_Gen_1 590 600 PF02991 0.451
LIG_LIR_Gen_1 607 617 PF02991 0.436
LIG_LIR_Gen_1 673 682 PF02991 0.508
LIG_LIR_Gen_1 804 814 PF02991 0.318
LIG_LIR_LC3C_4 297 302 PF02991 0.306
LIG_LIR_Nem_3 1020 1026 PF02991 0.378
LIG_LIR_Nem_3 1052 1057 PF02991 0.377
LIG_LIR_Nem_3 1116 1120 PF02991 0.447
LIG_LIR_Nem_3 1218 1224 PF02991 0.461
LIG_LIR_Nem_3 1257 1262 PF02991 0.447
LIG_LIR_Nem_3 1368 1373 PF02991 0.447
LIG_LIR_Nem_3 1412 1417 PF02991 0.450
LIG_LIR_Nem_3 1441 1445 PF02991 0.508
LIG_LIR_Nem_3 151 156 PF02991 0.314
LIG_LIR_Nem_3 388 394 PF02991 0.347
LIG_LIR_Nem_3 404 408 PF02991 0.255
LIG_LIR_Nem_3 416 422 PF02991 0.293
LIG_LIR_Nem_3 444 449 PF02991 0.437
LIG_LIR_Nem_3 590 595 PF02991 0.444
LIG_LIR_Nem_3 607 613 PF02991 0.501
LIG_LIR_Nem_3 625 631 PF02991 0.447
LIG_LIR_Nem_3 846 851 PF02991 0.447
LIG_LYPXL_yS_3 1221 1224 PF13949 0.447
LIG_MAD2 530 538 PF02301 0.488
LIG_MAD2 744 752 PF02301 0.258
LIG_MYND_1 649 653 PF01753 0.488
LIG_NRBOX 121 127 PF00104 0.571
LIG_NRBOX 467 473 PF00104 0.458
LIG_NRBOX 553 559 PF00104 0.533
LIG_NRBOX 781 787 PF00104 0.473
LIG_PCNA_PIPBox_1 452 461 PF02747 0.447
LIG_PCNA_yPIPBox_3 1376 1389 PF02747 0.533
LIG_PCNA_yPIPBox_3 447 459 PF02747 0.447
LIG_PDZ_Class_3 1562 1567 PF00595 0.461
LIG_Pex14_1 627 631 PF04695 0.447
LIG_Pex14_2 1011 1015 PF04695 0.416
LIG_Pex14_2 418 422 PF04695 0.446
LIG_Pex14_2 483 487 PF04695 0.425
LIG_Pex14_2 816 820 PF04695 0.447
LIG_REV1ctd_RIR_1 41 50 PF16727 0.389
LIG_SH2_CRK 1420 1424 PF00017 0.447
LIG_SH2_CRK 1442 1446 PF00017 0.533
LIG_SH2_CRK 345 349 PF00017 0.394
LIG_SH2_CRK 408 412 PF00017 0.394
LIG_SH2_CRK 848 852 PF00017 0.472
LIG_SH2_PTP2 592 595 PF00017 0.502
LIG_SH2_PTP2 971 974 PF00017 0.472
LIG_SH2_STAP1 1506 1510 PF00017 0.447
LIG_SH2_STAP1 408 412 PF00017 0.380
LIG_SH2_STAT3 1046 1049 PF00017 0.446
LIG_SH2_STAT3 1103 1106 PF00017 0.447
LIG_SH2_STAT3 517 520 PF00017 0.552
LIG_SH2_STAT3 800 803 PF00017 0.348
LIG_SH2_STAT5 1103 1106 PF00017 0.455
LIG_SH2_STAT5 1108 1111 PF00017 0.437
LIG_SH2_STAT5 1136 1139 PF00017 0.470
LIG_SH2_STAT5 1231 1234 PF00017 0.463
LIG_SH2_STAT5 1251 1254 PF00017 0.316
LIG_SH2_STAT5 21 24 PF00017 0.428
LIG_SH2_STAT5 391 394 PF00017 0.397
LIG_SH2_STAT5 410 413 PF00017 0.385
LIG_SH2_STAT5 458 461 PF00017 0.438
LIG_SH2_STAT5 514 517 PF00017 0.447
LIG_SH2_STAT5 592 595 PF00017 0.464
LIG_SH2_STAT5 687 690 PF00017 0.533
LIG_SH2_STAT5 74 77 PF00017 0.418
LIG_SH2_STAT5 800 803 PF00017 0.364
LIG_SH2_STAT5 925 928 PF00017 0.447
LIG_SH2_STAT5 971 974 PF00017 0.461
LIG_SH2_STAT5 983 986 PF00017 0.422
LIG_SH3_3 1027 1033 PF00018 0.484
LIG_SH3_3 1290 1296 PF00018 0.447
LIG_SH3_3 1533 1539 PF00018 0.447
LIG_SH3_3 851 857 PF00018 0.447
LIG_SUMO_SIM_anti_2 120 126 PF11976 0.331
LIG_SUMO_SIM_anti_2 299 306 PF11976 0.315
LIG_SUMO_SIM_anti_2 590 597 PF11976 0.472
LIG_SUMO_SIM_anti_2 966 971 PF11976 0.489
LIG_SUMO_SIM_par_1 1348 1354 PF11976 0.533
LIG_SUMO_SIM_par_1 1501 1507 PF11976 0.447
LIG_SUMO_SIM_par_1 537 542 PF11976 0.473
LIG_SUMO_SIM_par_1 677 683 PF11976 0.533
LIG_SUMO_SIM_par_1 744 750 PF11976 0.354
LIG_TRAF2_1 1405 1408 PF00917 0.458
LIG_TRAF2_1 448 451 PF00917 0.451
LIG_TRAF2_1 703 706 PF00917 0.447
LIG_TRAF2_1 85 88 PF00917 0.570
LIG_TYR_ITSM 588 595 PF00017 0.371
LIG_UBA3_1 1348 1356 PF00899 0.371
LIG_UBA3_1 668 675 PF00899 0.458
LIG_WRC_WIRS_1 524 529 PF05994 0.447
MOD_CDK_SPK_2 1067 1072 PF00069 0.447
MOD_CK1_1 1001 1007 PF00069 0.354
MOD_CK1_1 1056 1062 PF00069 0.315
MOD_CK1_1 1080 1086 PF00069 0.447
MOD_CK1_1 1324 1330 PF00069 0.496
MOD_CK1_1 1342 1348 PF00069 0.377
MOD_CK1_1 1368 1374 PF00069 0.458
MOD_CK1_1 1488 1494 PF00069 0.465
MOD_CK1_1 1501 1507 PF00069 0.430
MOD_CK1_1 1529 1535 PF00069 0.511
MOD_CK1_1 1561 1567 PF00069 0.460
MOD_CK1_1 288 294 PF00069 0.590
MOD_CK1_1 371 377 PF00069 0.410
MOD_CK1_1 507 513 PF00069 0.451
MOD_CK1_1 542 548 PF00069 0.507
MOD_CK1_1 747 753 PF00069 0.319
MOD_CK1_1 871 877 PF00069 0.391
MOD_CK1_1 899 905 PF00069 0.427
MOD_CK2_1 1 7 PF00069 0.483
MOD_CK2_1 1184 1190 PF00069 0.500
MOD_CK2_1 1244 1250 PF00069 0.522
MOD_CK2_1 1402 1408 PF00069 0.448
MOD_CK2_1 1501 1507 PF00069 0.447
MOD_CK2_1 278 284 PF00069 0.465
MOD_CK2_1 360 366 PF00069 0.511
MOD_CK2_1 421 427 PF00069 0.493
MOD_CK2_1 516 522 PF00069 0.458
MOD_CK2_1 547 553 PF00069 0.466
MOD_CK2_1 82 88 PF00069 0.461
MOD_Cter_Amidation 1453 1456 PF01082 0.247
MOD_GlcNHglycan 1058 1061 PF01048 0.420
MOD_GlcNHglycan 1083 1086 PF01048 0.261
MOD_GlcNHglycan 1278 1281 PF01048 0.286
MOD_GlcNHglycan 1326 1329 PF01048 0.333
MOD_GlcNHglycan 1366 1370 PF01048 0.247
MOD_GlcNHglycan 1404 1407 PF01048 0.267
MOD_GlcNHglycan 193 196 PF01048 0.448
MOD_GlcNHglycan 208 211 PF01048 0.412
MOD_GlcNHglycan 294 297 PF01048 0.435
MOD_GlcNHglycan 370 373 PF01048 0.553
MOD_GlcNHglycan 374 377 PF01048 0.507
MOD_GlcNHglycan 494 497 PF01048 0.288
MOD_GlcNHglycan 506 509 PF01048 0.194
MOD_GlcNHglycan 541 544 PF01048 0.303
MOD_GlcNHglycan 549 552 PF01048 0.298
MOD_GlcNHglycan 804 807 PF01048 0.347
MOD_GlcNHglycan 952 955 PF01048 0.193
MOD_GlcNHglycan 96 99 PF01048 0.518
MOD_GSK3_1 1015 1022 PF00069 0.351
MOD_GSK3_1 1049 1056 PF00069 0.375
MOD_GSK3_1 1077 1084 PF00069 0.499
MOD_GSK3_1 1155 1162 PF00069 0.508
MOD_GSK3_1 1323 1330 PF00069 0.371
MOD_GSK3_1 1365 1372 PF00069 0.533
MOD_GSK3_1 1434 1441 PF00069 0.447
MOD_GSK3_1 1470 1477 PF00069 0.533
MOD_GSK3_1 1508 1515 PF00069 0.455
MOD_GSK3_1 1557 1564 PF00069 0.551
MOD_GSK3_1 181 188 PF00069 0.519
MOD_GSK3_1 288 295 PF00069 0.512
MOD_GSK3_1 368 375 PF00069 0.364
MOD_GSK3_1 539 546 PF00069 0.474
MOD_GSK3_1 56 63 PF00069 0.612
MOD_GSK3_1 587 594 PF00069 0.515
MOD_GSK3_1 868 875 PF00069 0.512
MOD_GSK3_1 90 97 PF00069 0.468
MOD_GSK3_1 959 966 PF00069 0.472
MOD_GSK3_1 997 1004 PF00069 0.281
MOD_N-GLC_1 1049 1054 PF02516 0.378
MOD_N-GLC_1 1067 1072 PF02516 0.192
MOD_N-GLC_1 1147 1152 PF02516 0.258
MOD_N-GLC_1 1206 1211 PF02516 0.313
MOD_N-GLC_1 1244 1249 PF02516 0.322
MOD_N-GLC_1 605 610 PF02516 0.333
MOD_N-GLC_1 94 99 PF02516 0.562
MOD_N-GLC_2 642 644 PF02516 0.352
MOD_NEK2_1 1 6 PF00069 0.483
MOD_NEK2_1 1099 1104 PF00069 0.533
MOD_NEK2_1 1134 1139 PF00069 0.447
MOD_NEK2_1 1276 1281 PF00069 0.533
MOD_NEK2_1 1314 1319 PF00069 0.371
MOD_NEK2_1 1323 1328 PF00069 0.346
MOD_NEK2_1 303 308 PF00069 0.504
MOD_NEK2_1 515 520 PF00069 0.488
MOD_NEK2_1 539 544 PF00069 0.506
MOD_NEK2_1 56 61 PF00069 0.613
MOD_NEK2_1 708 713 PF00069 0.447
MOD_NEK2_1 785 790 PF00069 0.404
MOD_NEK2_1 82 87 PF00069 0.485
MOD_NEK2_1 868 873 PF00069 0.447
MOD_NEK2_1 910 915 PF00069 0.373
MOD_NEK2_1 997 1002 PF00069 0.500
MOD_NEK2_2 934 939 PF00069 0.469
MOD_PIKK_1 1083 1089 PF00454 0.447
MOD_PIKK_1 1149 1155 PF00454 0.401
MOD_PIKK_1 181 187 PF00454 0.476
MOD_PIKK_1 486 492 PF00454 0.458
MOD_PIKK_1 516 522 PF00454 0.552
MOD_PIKK_1 543 549 PF00454 0.533
MOD_PIKK_1 708 714 PF00454 0.447
MOD_PIKK_1 945 951 PF00454 0.517
MOD_PKA_1 504 510 PF00069 0.447
MOD_PKA_2 1171 1177 PF00069 0.553
MOD_PKA_2 1190 1196 PF00069 0.496
MOD_PKA_2 12 18 PF00069 0.472
MOD_PKA_2 1342 1348 PF00069 0.447
MOD_PKA_2 266 272 PF00069 0.418
MOD_PKA_2 291 297 PF00069 0.564
MOD_PKA_2 504 510 PF00069 0.470
MOD_PKA_2 835 841 PF00069 0.447
MOD_PKA_2 899 905 PF00069 0.432
MOD_PKA_2 90 96 PF00069 0.573
MOD_PKB_1 484 492 PF00069 0.375
MOD_Plk_1 1019 1025 PF00069 0.344
MOD_Plk_1 120 126 PF00069 0.565
MOD_Plk_1 1206 1212 PF00069 0.508
MOD_Plk_1 1244 1250 PF00069 0.516
MOD_Plk_1 1365 1371 PF00069 0.447
MOD_Plk_1 1547 1553 PF00069 0.486
MOD_Plk_1 259 265 PF00069 0.461
MOD_Plk_1 285 291 PF00069 0.537
MOD_Plk_1 322 328 PF00069 0.465
MOD_Plk_1 36 42 PF00069 0.482
MOD_Plk_1 605 611 PF00069 0.506
MOD_Plk_1 998 1004 PF00069 0.483
MOD_Plk_2-3 1211 1217 PF00069 0.472
MOD_Plk_2-3 404 410 PF00069 0.495
MOD_Plk_4 120 126 PF00069 0.456
MOD_Plk_4 1244 1250 PF00069 0.522
MOD_Plk_4 1282 1288 PF00069 0.499
MOD_Plk_4 1498 1504 PF00069 0.448
MOD_Plk_4 208 214 PF00069 0.444
MOD_Plk_4 285 291 PF00069 0.553
MOD_Plk_4 36 42 PF00069 0.479
MOD_Plk_4 378 384 PF00069 0.441
MOD_Plk_4 902 908 PF00069 0.456
MOD_ProDKin_1 1067 1073 PF00069 0.447
MOD_ProDKin_1 1327 1333 PF00069 0.447
MOD_ProDKin_1 185 191 PF00069 0.479
MOD_ProDKin_1 331 337 PF00069 0.398
MOD_ProDKin_1 60 66 PF00069 0.540
MOD_ProDKin_1 645 651 PF00069 0.452
MOD_ProDKin_1 662 668 PF00069 0.400
MOD_ProDKin_1 853 859 PF00069 0.447
MOD_ProDKin_1 874 880 PF00069 0.484
MOD_ProDKin_1 924 930 PF00069 0.488
MOD_ProDKin_1 959 965 PF00069 0.533
MOD_SUMO_rev_2 1214 1222 PF00179 0.458
MOD_SUMO_rev_2 1402 1411 PF00179 0.552
MOD_SUMO_rev_2 450 455 PF00179 0.447
MOD_SUMO_rev_2 671 676 PF00179 0.475
TRG_AP2beta_CARGO_1 151 160 PF09066 0.446
TRG_DiLeu_BaEn_1 121 126 PF01217 0.464
TRG_DiLeu_BaEn_1 1467 1472 PF01217 0.447
TRG_DiLeu_BaEn_1 316 321 PF01217 0.425
TRG_DiLeu_BaEn_1 390 395 PF01217 0.341
TRG_DiLeu_BaEn_1 553 558 PF01217 0.472
TRG_DiLeu_BaEn_1 78 83 PF01217 0.497
TRG_DiLeu_BaEn_2 151 157 PF01217 0.437
TRG_DiLeu_BaEn_2 1561 1567 PF01217 0.487
TRG_DiLeu_BaEn_2 845 851 PF01217 0.447
TRG_DiLeu_BaEn_4 316 322 PF01217 0.510
TRG_DiLeu_BaLyEn_6 1480 1485 PF01217 0.447
TRG_DiLeu_BaLyEn_6 535 540 PF01217 0.508
TRG_DiLeu_BaLyEn_6 781 786 PF01217 0.412
TRG_DiLeu_LyEn_5 553 558 PF01217 0.533
TRG_ENDOCYTIC_2 104 107 PF00928 0.449
TRG_ENDOCYTIC_2 1044 1047 PF00928 0.381
TRG_ENDOCYTIC_2 1117 1120 PF00928 0.447
TRG_ENDOCYTIC_2 1221 1224 PF00928 0.452
TRG_ENDOCYTIC_2 1420 1423 PF00928 0.447
TRG_ENDOCYTIC_2 1442 1445 PF00928 0.533
TRG_ENDOCYTIC_2 391 394 PF00928 0.359
TRG_ENDOCYTIC_2 408 411 PF00928 0.158
TRG_ENDOCYTIC_2 458 461 PF00928 0.446
TRG_ENDOCYTIC_2 583 586 PF00928 0.447
TRG_ENDOCYTIC_2 592 595 PF00928 0.447
TRG_ENDOCYTIC_2 628 631 PF00928 0.447
TRG_ENDOCYTIC_2 687 690 PF00928 0.456
TRG_ENDOCYTIC_2 704 707 PF00928 0.406
TRG_ENDOCYTIC_2 817 820 PF00928 0.458
TRG_ENDOCYTIC_2 848 851 PF00928 0.472
TRG_ER_diArg_1 339 341 PF00400 0.466
TRG_ER_diArg_1 633 635 PF00400 0.447
TRG_ER_diArg_1 782 784 PF00400 0.289
TRG_ER_diArg_1 897 900 PF00400 0.515
TRG_ER_diArg_1 956 958 PF00400 0.430
TRG_NES_CRM1_1 114 128 PF08389 0.312
TRG_NES_CRM1_1 140 154 PF08389 0.363
TRG_NES_CRM1_1 1548 1562 PF08389 0.472
TRG_NES_CRM1_1 677 691 PF08389 0.520
TRG_NES_CRM1_1 705 719 PF08389 0.488
TRG_NLS_MonoExtC_3 47 52 PF00514 0.227
TRG_NLS_MonoExtN_4 1453 1459 PF00514 0.447
TRG_NLS_MonoExtN_4 46 52 PF00514 0.481
TRG_Pf-PMV_PEXEL_1 1072 1076 PF00026 0.247
TRG_Pf-PMV_PEXEL_1 1111 1116 PF00026 0.247
TRG_Pf-PMV_PEXEL_1 307 311 PF00026 0.407
TRG_Pf-PMV_PEXEL_1 385 390 PF00026 0.423
TRG_Pf-PMV_PEXEL_1 447 451 PF00026 0.258
TRG_Pf-PMV_PEXEL_1 469 474 PF00026 0.247

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P6L8 Leptomonas seymouri 84% 97%
A0A0N1PFE3 Leptomonas seymouri 25% 100%
A0A0S4JAX3 Bodo saltans 57% 93%
A0A1X0P5I4 Trypanosomatidae 67% 98%
A0A3Q8ICE2 Leishmania donovani 91% 97%
A0A3S7X436 Leishmania donovani 26% 100%
A0A422NX41 Trypanosoma rangeli 65% 98%
A4HIZ1 Leishmania braziliensis 27% 100%
A4I1A3 Leishmania infantum 92% 97%
A4I6A8 Leishmania infantum 26% 100%
B8JKD7 Danio rerio 30% 100%
D0A5J5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 60% 100%
E9AXD9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 97%
E9B1G4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 26% 100%
F4I366 Arabidopsis thaliana 30% 100%
O54888 Rattus norvegicus 30% 100%
O74633 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) 32% 100%
P20028 Drosophila melanogaster 29% 100%
P22138 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 32% 100%
P28365 Euplotoides octocarinatus 29% 100%
P70700 Mus musculus 30% 100%
Q4Q6P8 Leishmania major 26% 100%
Q4QA33 Leishmania major 92% 100%
Q54BM1 Dictyostelium discoideum 30% 100%
Q5REE8 Pongo abelii 31% 100%
Q75DS1 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) 32% 100%
Q9H9Y6 Homo sapiens 31% 100%
Q9P7X8 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 32% 100%
V5B7L4 Trypanosoma cruzi 64% 98%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS