VPS9 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Vacuolar sorting protein 9 (VPS9) domain containing protein, putative

Species:

Leishmania braziliensis

UniProt:

A4HED6_LEIBR

TriTrypDb:

LbrM.25.1920 , LBRM2903_250032500

Length:

749

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HED6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HED6

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	232	234	PF00675	0.628
CLV_NRD_NRD_1	277	279	PF00675	0.411
CLV_NRD_NRD_1	574	576	PF00675	0.526
CLV_PCSK_KEX2_1	232	234	PF00082	0.628
CLV_PCSK_KEX2_1	277	279	PF00082	0.411
CLV_PCSK_KEX2_1	574	576	PF00082	0.501
CLV_PCSK_SKI1_1	270	274	PF00082	0.406
CLV_PCSK_SKI1_1	344	348	PF00082	0.491
CLV_PCSK_SKI1_1	479	483	PF00082	0.223
CLV_PCSK_SKI1_1	575	579	PF00082	0.507

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKV2	Leptomonas seymouri	62%	89%
A0A0S4IXM9	Bodo saltans	34%	70%
A0A1X0NY26	Trypanosomatidae	39%	82%
A0A3S7WZE1	Leishmania donovani	87%	89%
A0A422P4H0	Trypanosoma rangeli	37%	80%
A4I1T3	Leishmania infantum	88%	89%
C9ZKD9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	81%
E9AXW7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	89%
Q4Q9K3	Leishmania major	86%	100%
V5BH11	Trypanosoma cruzi	40%	85%

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