Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HED0_LEIBR

TriTrypDb:

LbrM.25.1840 , LBRM2903_250031700

Length:

133


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	7
GO:0110165	cellular anatomical entity	1	7

A4HED0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HED0


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	123	127	PF00656	0.401
CLV_NRD_NRD_1	104	106	PF00675	0.580
CLV_NRD_NRD_1	48	50	PF00675	0.398
CLV_NRD_NRD_1	92	94	PF00675	0.582
CLV_PCSK_KEX2_1	116	118	PF00082	0.582
CLV_PCSK_KEX2_1	48	50	PF00082	0.403
CLV_PCSK_KEX2_1	92	94	PF00082	0.581
CLV_PCSK_PC1ET2_1	116	118	PF00082	0.595
DEG_Nend_UBRbox_2	1	3	PF02207	0.646
DOC_MAPK_gen_1	45	54	PF00069	0.491
DOC_MAPK_MEF2A_6	45	54	PF00069	0.506
DOC_PP4_FxxP_1	27	30	PF00568	0.561
DOC_USP7_MATH_1	85	89	PF00917	0.315
LIG_14-3-3_CanoR_1	105	110	PF00244	0.425
LIG_EH1_1	53	61	PF00400	0.287
LIG_FHA_1	108	114	PF00498	0.449
LIG_FHA_1	53	59	PF00498	0.318
LIG_FHA_2	106	112	PF00498	0.433
LIG_LIR_Apic_2	25	30	PF02991	0.568
LIG_LIR_Nem_3	110	115	PF02991	0.324
LIG_LIR_Nem_3	95	101	PF02991	0.352
LIG_NRP_CendR_1	131	133	PF00754	0.637
LIG_SH2_NCK_1	15	19	PF00017	0.596
LIG_SH2_STAT3	101	104	PF00017	0.344
LIG_SH2_STAT5	15	18	PF00017	0.552
LIG_SH2_STAT5	67	70	PF00017	0.418
LIG_SH2_STAT5	72	75	PF00017	0.361
LIG_SH3_3	59	65	PF00018	0.229
LIG_SUMO_SIM_anti_2	55	60	PF11976	0.184
LIG_TRAF2_1	121	124	PF00917	0.405
LIG_TRAF2_2	30	35	PF00917	0.521
MOD_CK2_1	105	111	PF00069	0.387
MOD_CK2_1	118	124	PF00069	0.439
MOD_CMANNOS	109	112	PF00535	0.615
MOD_GlcNHglycan	120	123	PF01048	0.657
MOD_GlcNHglycan	16	19	PF01048	0.480
MOD_GlcNHglycan	45	48	PF01048	0.422
MOD_N-GLC_1	118	123	PF02516	0.649
MOD_NEK2_1	100	105	PF00069	0.341
MOD_NEK2_1	52	57	PF00069	0.397
MOD_PIKK_1	100	106	PF00454	0.356
MOD_PKA_1	105	111	PF00069	0.426
MOD_PKA_2	83	89	PF00069	0.395
MOD_Plk_4	54	60	PF00069	0.327
MOD_Plk_4	85	91	PF00069	0.349
MOD_SUMO_rev_2	95	100	PF00179	0.319
TRG_ER_diArg_1	48	50	PF00400	0.593


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I3S0	Leptomonas seymouri	74%	94%
A0A0S4IXM4	Bodo saltans	56%	100%
A0A1X0NZL2	Trypanosomatidae	62%	97%
A0A3R7N4F6	Trypanosoma rangeli	68%	98%
C9ZKD3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	67%	99%