Elongation factor 2-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

elongation factor 2-like protein

Species:

Leishmania braziliensis

UniProt:

A4HEB0_LEIBR

TriTrypDb:

LbrM.25.1640 , LBRM2903_250029800

Length:

887

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0032991	protein-containing complex	1	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	1
GO:1990904	ribonucleoprotein complex	2	1

Expansion

Sequence features

A4HEB0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HEB0

Function

Biological processes
Term	Name	Level	Count
GO:0006996	organelle organization	4	1
GO:0009987	cellular process	1	1
GO:0016043	cellular component organization	3	1
GO:0022607	cellular component assembly	4	1
GO:0042255	ribosome assembly	7	1
GO:0042256	cytosolic ribosome assembly	8	1
GO:0070925	organelle assembly	5	1
GO:0071840	cellular component organization or biogenesis	2	1
GO:0140694	non-membrane-bounded organelle assembly	6	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003746	translation elongation factor activity	4	12
GO:0003824	catalytic activity	1	12
GO:0003924	GTPase activity	7	12
GO:0005488	binding	1	12
GO:0005525	GTP binding	5	12
GO:0008135	translation factor activity, RNA binding	3	12
GO:0016462	pyrophosphatase activity	5	12
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	12
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	12
GO:0017076	purine nucleotide binding	4	12
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	12
GO:0019001	guanyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032561	guanyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0045182	translation regulator activity	1	12
GO:0090079	translation regulator activity, nucleic acid binding	2	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12
GO:0043021	ribonucleoprotein complex binding	3	1
GO:0043022	ribosome binding	4	1
GO:0044877	protein-containing complex binding	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	118	122	PF00656	0.453
CLV_C14_Caspase3-7	826	830	PF00656	0.493
CLV_NRD_NRD_1	313	315	PF00675	0.467
CLV_NRD_NRD_1	351	353	PF00675	0.400
CLV_NRD_NRD_1	746	748	PF00675	0.361
CLV_NRD_NRD_1	774	776	PF00675	0.253
CLV_NRD_NRD_1	864	866	PF00675	0.430
CLV_PCSK_FUR_1	861	865	PF00082	0.383
CLV_PCSK_KEX2_1	313	315	PF00082	0.457
CLV_PCSK_KEX2_1	350	352	PF00082	0.422
CLV_PCSK_KEX2_1	639	641	PF00082	0.449
CLV_PCSK_KEX2_1	746	748	PF00082	0.361
CLV_PCSK_KEX2_1	773	775	PF00082	0.253
CLV_PCSK_KEX2_1	863	865	PF00082	0.419
CLV_PCSK_PC1ET2_1	639	641	PF00082	0.419
CLV_PCSK_PC1ET2_1	863	865	PF00082	0.515
CLV_PCSK_SKI1_1	321	325	PF00082	0.397
CLV_PCSK_SKI1_1	369	373	PF00082	0.457
CLV_PCSK_SKI1_1	475	479	PF00082	0.345
CLV_PCSK_SKI1_1	550	554	PF00082	0.386
CLV_PCSK_SKI1_1	66	70	PF00082	0.253
DEG_APCC_DBOX_1	316	324	PF00400	0.381
DEG_APCC_DBOX_1	349	357	PF00400	0.445
DEG_APCC_DBOX_1	792	800	PF00400	0.477
DEG_SCF_FBW7_1	469	474	PF00400	0.390
DEG_SPOP_SBC_1	587	591	PF00917	0.312
DOC_CYCLIN_RxL_1	317	326	PF00134	0.411
DOC_CYCLIN_yClb1_LxF_4	654	659	PF00134	0.432
DOC_CYCLIN_yClb5_NLxxxL_5	235	244	PF00134	0.434
DOC_CYCLIN_yCln2_LP_2	342	348	PF00134	0.396
DOC_MAPK_gen_1	165	172	PF00069	0.539
DOC_MAPK_gen_1	229	237	PF00069	0.526
DOC_MAPK_gen_1	262	269	PF00069	0.529
DOC_MAPK_gen_1	421	430	PF00069	0.402
DOC_MAPK_HePTP_8	520	532	PF00069	0.384
DOC_MAPK_MEF2A_6	136	145	PF00069	0.373
DOC_MAPK_MEF2A_6	262	271	PF00069	0.537
DOC_MAPK_MEF2A_6	523	532	PF00069	0.387
DOC_PP1_RVXF_1	654	660	PF00149	0.424
DOC_PP1_SILK_1	128	133	PF00149	0.493
DOC_USP7_MATH_1	569	573	PF00917	0.396
DOC_USP7_MATH_1	695	699	PF00917	0.403
DOC_USP7_MATH_1	82	86	PF00917	0.554
DOC_USP7_MATH_1	847	851	PF00917	0.425
DOC_USP7_UBL2_3	615	619	PF12436	0.589
DOC_USP7_UBL2_3	881	885	PF12436	0.567
DOC_WW_Pin1_4	255	260	PF00397	0.501
DOC_WW_Pin1_4	341	346	PF00397	0.362
DOC_WW_Pin1_4	361	366	PF00397	0.245
DOC_WW_Pin1_4	375	380	PF00397	0.337
DOC_WW_Pin1_4	44	49	PF00397	0.477
DOC_WW_Pin1_4	467	472	PF00397	0.363
DOC_WW_Pin1_4	90	95	PF00397	0.453
LIG_14-3-3_CanoR_1	132	136	PF00244	0.539
LIG_14-3-3_CanoR_1	351	357	PF00244	0.458
LIG_14-3-3_CanoR_1	500	504	PF00244	0.392
LIG_14-3-3_CanoR_1	66	71	PF00244	0.453
LIG_14-3-3_CanoR_1	773	782	PF00244	0.477
LIG_Actin_WH2_2	116	134	PF00022	0.453
LIG_Actin_WH2_2	410	425	PF00022	0.414
LIG_APCC_ABBA_1	428	433	PF00400	0.403
LIG_APCC_ABBAyCdc20_2	865	871	PF00400	0.464
LIG_BIR_II_1	1	5	PF00653	0.556
LIG_BIR_III_2	829	833	PF00653	0.453
LIG_BRCT_BRCA1_1	222	226	PF00533	0.509
LIG_BRCT_BRCA1_1	458	462	PF00533	0.485
LIG_BRCT_BRCA1_1	758	762	PF00533	0.558
LIG_BRCT_BRCA1_1	786	790	PF00533	0.464
LIG_CSK_EPIYA_1	704	708	PF00017	0.465
LIG_CSL_BTD_1	326	329	PF09270	0.446
LIG_deltaCOP1_diTrp_1	218	227	PF00928	0.453
LIG_deltaCOP1_diTrp_1	242	250	PF00928	0.436
LIG_deltaCOP1_diTrp_1	276	285	PF00928	0.351
LIG_deltaCOP1_diTrp_1	453	462	PF00928	0.254
LIG_deltaCOP1_diTrp_1	675	684	PF00928	0.427
LIG_EH1_1	394	402	PF00400	0.509
LIG_FHA_1	125	131	PF00498	0.513
LIG_FHA_1	252	258	PF00498	0.458
LIG_FHA_1	391	397	PF00498	0.417
LIG_FHA_1	4	10	PF00498	0.344
LIG_FHA_1	453	459	PF00498	0.489
LIG_FHA_1	468	474	PF00498	0.358
LIG_FHA_1	494	500	PF00498	0.420
LIG_FHA_1	587	593	PF00498	0.520
LIG_FHA_1	815	821	PF00498	0.445
LIG_FHA_1	82	88	PF00498	0.561
LIG_FHA_1	849	855	PF00498	0.497
LIG_FHA_2	132	138	PF00498	0.539
LIG_FHA_2	156	162	PF00498	0.477
LIG_FHA_2	32	38	PF00498	0.453
LIG_FHA_2	362	368	PF00498	0.566
LIG_FHA_2	540	546	PF00498	0.410
LIG_FHA_2	835	841	PF00498	0.481
LIG_LIR_Apic_2	200	206	PF02991	0.453
LIG_LIR_Apic_2	247	252	PF02991	0.493
LIG_LIR_Apic_2	306	312	PF02991	0.459
LIG_LIR_Apic_2	831	836	PF02991	0.530
LIG_LIR_Gen_1	160	170	PF02991	0.527
LIG_LIR_Gen_1	225	235	PF02991	0.389
LIG_LIR_Gen_1	474	483	PF02991	0.403
LIG_LIR_Gen_1	557	566	PF02991	0.372
LIG_LIR_Gen_1	675	683	PF02991	0.430
LIG_LIR_Gen_1	823	833	PF02991	0.477
LIG_LIR_Nem_3	160	166	PF02991	0.527
LIG_LIR_Nem_3	225	230	PF02991	0.374
LIG_LIR_Nem_3	276	282	PF02991	0.363
LIG_LIR_Nem_3	325	330	PF02991	0.375
LIG_LIR_Nem_3	408	414	PF02991	0.394
LIG_LIR_Nem_3	474	479	PF02991	0.396
LIG_LIR_Nem_3	487	491	PF02991	0.427
LIG_LIR_Nem_3	557	562	PF02991	0.367
LIG_LIR_Nem_3	675	681	PF02991	0.365
LIG_LIR_Nem_3	823	828	PF02991	0.464
LIG_NRBOX	319	325	PF00104	0.383
LIG_Pex14_1	245	249	PF04695	0.386
LIG_REV1ctd_RIR_1	224	233	PF16727	0.463
LIG_SH2_CRK	476	480	PF00017	0.364
LIG_SH2_CRK	768	772	PF00017	0.461
LIG_SH2_GRB2like	180	183	PF00017	0.513
LIG_SH2_NCK_1	476	480	PF00017	0.495
LIG_SH2_SRC	429	432	PF00017	0.445
LIG_SH2_STAP1	180	184	PF00017	0.513
LIG_SH2_STAP1	282	286	PF00017	0.447
LIG_SH2_STAP1	753	757	PF00017	0.464
LIG_SH2_STAT3	180	183	PF00017	0.513
LIG_SH2_STAT5	157	160	PF00017	0.538
LIG_SH2_STAT5	163	166	PF00017	0.540
LIG_SH2_STAT5	249	252	PF00017	0.411
LIG_SH2_STAT5	38	41	PF00017	0.453
LIG_SH2_STAT5	386	389	PF00017	0.332
LIG_SH2_STAT5	395	398	PF00017	0.468
LIG_SH2_STAT5	429	432	PF00017	0.395
LIG_SH2_STAT5	472	475	PF00017	0.365
LIG_SH2_STAT5	791	794	PF00017	0.443
LIG_SH2_STAT5	833	836	PF00017	0.445
LIG_SH3_3	326	332	PF00018	0.489
LIG_SH3_3	376	382	PF00018	0.402
LIG_SH3_3	480	486	PF00018	0.387
LIG_SH3_3	502	508	PF00018	0.530
LIG_SH3_3	88	94	PF00018	0.453
LIG_SUMO_SIM_anti_2	529	535	PF11976	0.349
LIG_SUMO_SIM_anti_2	609	618	PF11976	0.536
LIG_SUMO_SIM_par_1	113	118	PF11976	0.453
LIG_SUMO_SIM_par_1	489	497	PF11976	0.424
LIG_TRAF2_1	158	161	PF00917	0.453
LIG_TRAF2_1	290	293	PF00917	0.573
LIG_TRAF2_1	838	841	PF00917	0.507
LIG_TYR_ITSM	472	479	PF00017	0.484
LIG_UBA3_1	858	866	PF00899	0.460
LIG_WRC_WIRS_1	485	490	PF05994	0.278
LIG_WRC_WIRS_1	556	561	PF05994	0.395
LIG_WRC_WIRS_1	570	575	PF05994	0.347
MOD_CDK_SPxxK_3	255	262	PF00069	0.582
MOD_CK1_1	2	8	PF00069	0.405
MOD_CK1_1	481	487	PF00069	0.478
MOD_CK1_1	579	585	PF00069	0.572
MOD_CK1_1	652	658	PF00069	0.521
MOD_CK1_1	722	728	PF00069	0.456
MOD_CK1_1	760	766	PF00069	0.479
MOD_CK2_1	131	137	PF00069	0.539
MOD_CK2_1	155	161	PF00069	0.453
MOD_CK2_1	165	171	PF00069	0.453
MOD_CK2_1	286	292	PF00069	0.502
MOD_CK2_1	361	367	PF00069	0.578
MOD_CK2_1	539	545	PF00069	0.408
MOD_CK2_1	569	575	PF00069	0.382
MOD_CK2_1	588	594	PF00069	0.321
MOD_CK2_1	729	735	PF00069	0.514
MOD_CK2_1	820	826	PF00069	0.561
MOD_CK2_1	834	840	PF00069	0.313
MOD_GlcNHglycan	11	15	PF01048	0.500
MOD_GlcNHglycan	282	285	PF01048	0.313
MOD_GlcNHglycan	288	291	PF01048	0.431
MOD_GlcNHglycan	418	421	PF01048	0.324
MOD_GlcNHglycan	457	461	PF01048	0.334
MOD_GlcNHglycan	480	483	PF01048	0.273
MOD_GlcNHglycan	581	584	PF01048	0.619
MOD_GlcNHglycan	620	623	PF01048	0.535
MOD_GlcNHglycan	641	644	PF01048	0.498
MOD_GlcNHglycan	651	654	PF01048	0.342
MOD_GlcNHglycan	697	700	PF01048	0.377
MOD_GlcNHglycan	721	724	PF01048	0.394
MOD_GlcNHglycan	759	762	PF01048	0.277
MOD_GSK3_1	121	128	PF00069	0.457
MOD_GSK3_1	151	158	PF00069	0.509
MOD_GSK3_1	251	258	PF00069	0.526
MOD_GSK3_1	337	344	PF00069	0.457
MOD_GSK3_1	452	459	PF00069	0.431
MOD_GSK3_1	467	474	PF00069	0.367
MOD_GSK3_1	477	484	PF00069	0.372
MOD_GSK3_1	528	535	PF00069	0.437
MOD_GSK3_1	569	576	PF00069	0.372
MOD_GSK3_1	66	73	PF00069	0.453
MOD_GSK3_1	753	760	PF00069	0.457
MOD_GSK3_1	769	776	PF00069	0.433
MOD_GSK3_1	809	816	PF00069	0.456
MOD_GSK3_1	97	104	PF00069	0.453
MOD_N-GLC_1	238	243	PF02516	0.413
MOD_N-GLC_1	579	584	PF02516	0.649
MOD_N-GLC_2	21	23	PF02516	0.253
MOD_NEK2_1	131	136	PF00069	0.512
MOD_NEK2_1	150	155	PF00069	0.356
MOD_NEK2_1	212	217	PF00069	0.477
MOD_NEK2_1	286	291	PF00069	0.506
MOD_NEK2_1	323	328	PF00069	0.291
MOD_NEK2_1	39	44	PF00069	0.453
MOD_NEK2_1	390	395	PF00069	0.436
MOD_NEK2_1	493	498	PF00069	0.496
MOD_NEK2_1	555	560	PF00069	0.372
MOD_NEK2_1	56	61	PF00069	0.453
MOD_NEK2_1	573	578	PF00069	0.373
MOD_NEK2_1	597	602	PF00069	0.358
MOD_NEK2_1	70	75	PF00069	0.453
MOD_NEK2_1	711	716	PF00069	0.499
MOD_NEK2_1	820	825	PF00069	0.464
MOD_NEK2_2	569	574	PF00069	0.402
MOD_NEK2_2	753	758	PF00069	0.464
MOD_PIKK_1	121	127	PF00454	0.453
MOD_PIKK_1	151	157	PF00454	0.539
MOD_PIKK_1	390	396	PF00454	0.394
MOD_PIKK_1	760	766	PF00454	0.464
MOD_PIKK_1	809	815	PF00454	0.464
MOD_PK_1	165	171	PF00069	0.477
MOD_PK_1	71	77	PF00069	0.453
MOD_PKA_1	313	319	PF00069	0.323
MOD_PKA_1	639	645	PF00069	0.488
MOD_PKA_1	773	779	PF00069	0.477
MOD_PKA_2	131	137	PF00069	0.539
MOD_PKA_2	313	319	PF00069	0.323
MOD_PKA_2	499	505	PF00069	0.375
MOD_PKA_2	573	579	PF00069	0.384
MOD_PKA_2	639	645	PF00069	0.480
MOD_PKA_2	773	779	PF00069	0.477
MOD_PKB_1	350	358	PF00069	0.520
MOD_Plk_1	437	443	PF00069	0.474
MOD_Plk_1	452	458	PF00069	0.496
MOD_Plk_1	528	534	PF00069	0.431
MOD_Plk_1	753	759	PF00069	0.464
MOD_Plk_2-3	196	202	PF00069	0.493
MOD_Plk_2-3	288	294	PF00069	0.577
MOD_Plk_4	126	132	PF00069	0.464
MOD_Plk_4	323	329	PF00069	0.390
MOD_Plk_4	352	358	PF00069	0.503
MOD_Plk_4	440	446	PF00069	0.510
MOD_Plk_4	494	500	PF00069	0.410
MOD_Plk_4	528	534	PF00069	0.445
MOD_Plk_4	573	579	PF00069	0.426
MOD_Plk_4	588	594	PF00069	0.487
MOD_Plk_4	684	690	PF00069	0.389
MOD_Plk_4	753	759	PF00069	0.464
MOD_ProDKin_1	255	261	PF00069	0.501
MOD_ProDKin_1	341	347	PF00069	0.368
MOD_ProDKin_1	361	367	PF00069	0.247
MOD_ProDKin_1	375	381	PF00069	0.331
MOD_ProDKin_1	44	50	PF00069	0.477
MOD_ProDKin_1	467	473	PF00069	0.359
MOD_ProDKin_1	90	96	PF00069	0.453
MOD_SUMO_rev_2	247	254	PF00179	0.502
MOD_SUMO_rev_2	361	371	PF00179	0.566
MOD_SUMO_rev_2	612	621	PF00179	0.557
TRG_DiLeu_BaEn_1	392	397	PF01217	0.319
TRG_DiLeu_BaEn_1	609	614	PF01217	0.504
TRG_DiLeu_BaLyEn_6	516	521	PF01217	0.416
TRG_DiLeu_BaLyEn_6	52	57	PF01217	0.453
TRG_ENDOCYTIC_2	163	166	PF00928	0.453
TRG_ENDOCYTIC_2	282	285	PF00928	0.367
TRG_ENDOCYTIC_2	476	479	PF00928	0.367
TRG_ENDOCYTIC_2	768	771	PF00928	0.461
TRG_ER_diArg_1	164	167	PF00400	0.453
TRG_ER_diArg_1	312	314	PF00400	0.452
TRG_ER_diArg_1	350	352	PF00400	0.422
TRG_ER_diArg_1	745	747	PF00400	0.377
TRG_ER_diArg_1	773	775	PF00400	0.453
TRG_NES_CRM1_1	554	568	PF08389	0.387
TRG_NLS_MonoCore_2	862	867	PF00514	0.516
TRG_NLS_MonoExtN_4	861	867	PF00514	0.519
TRG_Pf-PMV_PEXEL_1	167	171	PF00026	0.264
TRG_Pf-PMV_PEXEL_1	296	300	PF00026	0.544
TRG_Pf-PMV_PEXEL_1	509	513	PF00026	0.557
TRG_Pf-PMV_PEXEL_1	550	554	PF00026	0.386
TRG_Pf-PMV_PEXEL_1	604	609	PF00026	0.416
TRG_Pf-PMV_PEXEL_1	746	750	PF00026	0.305

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I9M7	Leptomonas seymouri	85%	100%
A0A0N1PBS6	Leptomonas seymouri	31%	100%
A0A0S4JM05	Bodo saltans	31%	100%
A0A0S4JP20	Bodo saltans	55%	90%
A0A1X0NY54	Trypanosomatidae	71%	99%
A0A1X0P8P3	Trypanosomatidae	31%	100%
A0A3Q8IIX7	Leishmania donovani	31%	100%
A0A3R7MX75	Trypanosoma rangeli	68%	100%
A0A3R7NHC0	Trypanosoma rangeli	31%	100%
A0A3S7WZE0	Leishmania donovani	92%	100%
A0A422N8J1	Trypanosoma rangeli	25%	93%
A0B7D5	Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)	27%	100%
A0SXL6	Callithrix jacchus	31%	100%
A3CXM8	Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)	27%	100%
A4FUD3	Bos taurus	26%	91%
A4HNM7	Leishmania braziliensis	31%	100%
A4I1Q6	Leishmania infantum	92%	100%
A4ICW8	Leishmania infantum	31%	100%
A5DI11	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	31%	100%
A5ULM6	Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)	27%	100%
A6UV44	Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)	27%	100%
B0R8C8	Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)	28%	100%
C3MQ53	Sulfolobus islandicus (strain L.S.2.15 / Lassen #1)	27%	100%
C3MVH1	Sulfolobus islandicus (strain M.14.25 / Kamchatka #1)	27%	100%
C3N5S0	Sulfolobus islandicus (strain M.16.27)	27%	100%
C3NED6	Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1)	27%	100%
C3NHB6	Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2)	27%	100%
C4KHE9	Sulfolobus islandicus (strain M.16.4 / Kamchatka #3)	27%	100%
C4YJQ8	Candida albicans (strain WO-1)	31%	100%
C7NYH7	Halomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541)	28%	100%
C9ZKB0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	69%	100%
D0A2I0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	100%
E9ASD6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9AXU0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
F4JWP9	Arabidopsis thaliana	28%	91%
O08810	Mus musculus	26%	91%
O14460	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	31%	100%
O23755	Beta vulgaris	32%	100%
O27131	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	27%	100%
O74945	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	89%
O94316	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	90%
P05197	Rattus norvegicus	31%	100%
P09445	Cricetulus griseus	30%	100%
P13060	Drosophila melanogaster	32%	100%
P13639	Homo sapiens	31%	100%
P15112	Dictyostelium discoideum	32%	100%
P23112	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	26%	100%
P28996	Parachlorella kessleri	32%	100%
P29691	Caenorhabditis elegans	31%	100%
P30925	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	27%	100%
P32324	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	31%	100%
P36048	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	88%
P58252	Mus musculus	31%	100%
Q06193	Entamoeba histolytica	31%	100%
Q15029	Homo sapiens	26%	91%
Q17152	Blastocystis hominis	31%	100%
Q1HPK6	Bombyx mori	32%	100%
Q23716	Cryptosporidium parvum	32%	100%
Q2NEL0	Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)	26%	100%
Q3SYU2	Bos taurus	31%	100%
Q4Q259	Leishmania major	31%	93%
Q4Q9N1	Leishmania major	92%	100%
Q5A0M4	Candida albicans (strain SC5314 / ATCC MYA-2876)	31%	100%
Q5F3X4	Gallus gallus	26%	91%
Q5R6E0	Pongo abelii	26%	91%
Q5R8Z3	Pongo abelii	31%	100%
Q6BJ25	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	31%	100%
Q6CPQ9	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	31%	100%
Q6FYA7	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	30%	100%
Q6L200	Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)	28%	100%
Q754C8	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	31%	100%
Q7Z2Z2	Homo sapiens	30%	79%
Q874B9	Komagataella pastoris	30%	100%
Q875S0	Lachancea kluyveri (strain ATCC 58438 / CBS 3082 / BCRC 21498 / NBRC 1685 / JCM 7257 / NCYC 543 / NRRL Y-12651)	31%	100%
Q875Z2	Naumovozyma castellii (strain ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC 1992 / NRRL Y-12630)	31%	100%
Q8SQT7	Encephalitozoon cuniculi (strain GB-M1)	28%	100%
Q90705	Gallus gallus	31%	100%
Q96X45	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	31%	100%
Q975H5	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	27%	100%
Q9ASR1	Arabidopsis thaliana	32%	100%
Q9HM85	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	28%	100%
Q9LNC5	Arabidopsis thaliana	28%	90%
Q9YC19	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	28%	100%
V5AW74	Trypanosoma cruzi	25%	93%
V5BI00	Trypanosoma cruzi	69%	100%
V5DRS6	Trypanosoma cruzi	31%	100%