Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4HE83_LEIBR

TriTrypDb:

LbrM.25.1370 , LBRM2903_040006100

Length:

154

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HE83

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HE83

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	15	17	PF00675	0.511
CLV_NRD_NRD_1	2	4	PF00675	0.702
CLV_NRD_NRD_1	71	73	PF00675	0.613
CLV_PCSK_KEX2_1	15	17	PF00082	0.511
CLV_PCSK_KEX2_1	2	4	PF00082	0.702
CLV_PCSK_KEX2_1	71	73	PF00082	0.613
CLV_PCSK_PC7_1	11	17	PF00082	0.519
CLV_PCSK_SKI1_1	61	65	PF00082	0.420
DEG_APCC_DBOX_1	60	68	PF00400	0.418
DEG_APCC_DBOX_1	71	79	PF00400	0.498
DEG_Nend_UBRbox_1	1	4	PF02207	0.656
DEG_SCF_FBW7_2	96	102	PF00400	0.350
DOC_CKS1_1	96	101	PF01111	0.348
DOC_CYCLIN_RxL_1	98	109	PF00134	0.394
DOC_MAPK_MEF2A_6	61	69	PF00069	0.415
DOC_PP1_RVXF_1	99	106	PF00149	0.395
DOC_USP7_MATH_1	137	141	PF00917	0.662
DOC_WW_Pin1_4	95	100	PF00397	0.362
LIG_14-3-3_CanoR_1	111	118	PF00244	0.390
LIG_14-3-3_CanoR_1	15	25	PF00244	0.597
LIG_14-3-3_CanoR_1	30	35	PF00244	0.551
LIG_FHA_1	141	147	PF00498	0.470
LIG_FHA_2	54	60	PF00498	0.598
LIG_LIR_Nem_3	57	63	PF02991	0.429
LIG_NRBOX	63	69	PF00104	0.413
LIG_PDZ_Class_2	149	154	PF00595	0.565
LIG_SH2_CRK	60	64	PF00017	0.421
LIG_SH3_3	18	24	PF00018	0.512
LIG_SH3_3	49	55	PF00018	0.531
MOD_CDK_SPxK_1	95	101	PF00069	0.352
MOD_CK1_1	14	20	PF00069	0.521
MOD_CK1_1	140	146	PF00069	0.478
MOD_CK1_1	33	39	PF00069	0.518
MOD_CK1_1	45	51	PF00069	0.656
MOD_CK2_1	145	151	PF00069	0.506
MOD_GlcNHglycan	135	138	PF01048	0.510
MOD_GlcNHglycan	44	47	PF01048	0.599
MOD_GSK3_1	10	17	PF00069	0.577
MOD_GSK3_1	133	140	PF00069	0.586
MOD_GSK3_1	40	47	PF00069	0.648
MOD_N-GLC_1	40	45	PF02516	0.609
MOD_PKA_1	15	21	PF00069	0.596
MOD_PKA_1	71	77	PF00069	0.493
MOD_PKA_2	10	16	PF00069	0.594
MOD_PKA_2	71	77	PF00069	0.493
MOD_Plk_4	30	36	PF00069	0.499
MOD_ProDKin_1	95	101	PF00069	0.363
MOD_SUMO_rev_2	85	93	PF00179	0.455
TRG_ENDOCYTIC_2	60	63	PF00928	0.421
TRG_ER_diArg_1	1	3	PF00400	0.711
TRG_ER_diArg_1	70	72	PF00400	0.609
TRG_NES_CRM1_1	108	119	PF08389	0.390
TRG_Pf-PMV_PEXEL_1	111	115	PF00026	0.513
TRG_Pf-PMV_PEXEL_1	61	66	PF00026	0.419

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PC29	Leptomonas seymouri	43%	75%
A0A3S5H575	Leishmania donovani	61%	97%
A4H3S9	Leishmania braziliensis	82%	100%
A4HS04	Leishmania infantum	60%	97%
E9AJZ2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	59%	97%
Q9BLQ6	Leishmania major	62%	100%