LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HE51_LEIBR
TriTrypDb:
LbrM.25.1050 , LBRM2903_250019700 *
Length:
2580

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 2
GO:0005929 cilium 4 1
GO:0005930 axoneme 2 1
GO:0042995 cell projection 2 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0110165 cellular anatomical entity 1 2
GO:0120025 plasma membrane bounded cell projection 3 1
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Expansion

Sequence features

A4HE51
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
TermNameLevelCount
GO:0008285 negative regulation of cell population proliferation 5 7
GO:0042127 regulation of cell population proliferation 4 7
GO:0048519 negative regulation of biological process 3 7
GO:0048523 negative regulation of cellular process 4 7
GO:0050789 regulation of biological process 2 7
GO:0050794 regulation of cellular process 3 7
GO:0065007 biological regulation 1 7
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Molecular functions
TermNameLevelCount
GO:0005488 binding 1 1
GO:0005515 protein binding 2 1
GO:0008092 cytoskeletal protein binding 3 1
GO:0015631 tubulin binding 4 1
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 1369 1373 PF00656 0.487
CLV_C14_Caspase3-7 1755 1759 PF00656 0.347
CLV_C14_Caspase3-7 2268 2272 PF00656 0.503
CLV_C14_Caspase3-7 2296 2300 PF00656 0.404
CLV_C14_Caspase3-7 2350 2354 PF00656 0.388
CLV_C14_Caspase3-7 2357 2361 PF00656 0.368
CLV_C14_Caspase3-7 2427 2431 PF00656 0.377
CLV_C14_Caspase3-7 409 413 PF00656 0.636
CLV_C14_Caspase3-7 640 644 PF00656 0.664
CLV_C14_Caspase3-7 763 767 PF00656 0.666
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I5U7 Leptomonas seymouri 48% 99%
A0A3Q8ICD6 Leishmania donovani 75% 100%
A4I1H9 Leishmania infantum 75% 99%
E9AXL4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 72% 100%
Q4Q9V8 Leishmania major 73% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS