Perilipin-3-like

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Perilipin-3-like

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HE42_LEIBR

TriTrypDb:

LbrM.25.0950 , LBRM2903_250018700 , LBRM2903_250018800

Length:

754

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HE42

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HE42

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	665	669	PF00656	0.686
CLV_NRD_NRD_1	517	519	PF00675	0.505
CLV_PCSK_FUR_1	515	519	PF00082	0.496
CLV_PCSK_KEX2_1	398	400	PF00082	0.339
CLV_PCSK_KEX2_1	517	519	PF00082	0.497
CLV_PCSK_PC1ET2_1	398	400	PF00082	0.339
CLV_PCSK_SKI1_1	309	313	PF00082	0.691
CLV_PCSK_SKI1_1	506	510	PF00082	0.658
CLV_PCSK_SKI1_1	518	522	PF00082	0.552
CLV_PCSK_SKI1_1	701	705	PF00082	0.564
DEG_Nend_Nbox_1	1	3	PF02207	0.528
DOC_CDC14_PxL_1	521	529	PF14671	0.624
DOC_CKS1_1	314	319	PF01111	0.596
DOC_CKS1_1	324	329	PF01111	0.663
DOC_CKS1_1	528	533	PF01111	0.659
DOC_CKS1_1	622	627	PF01111	0.542
DOC_CKS1_1	675	680	PF01111	0.533
DOC_CYCLIN_yClb5_NLxxxL_5	469	475	PF00134	0.457
DOC_CYCLIN_yCln2_LP_2	675	681	PF00134	0.535
DOC_MAPK_DCC_7	519	529	PF00069	0.500
DOC_MAPK_gen_1	328	337	PF00069	0.534
DOC_MAPK_gen_1	412	421	PF00069	0.349
DOC_MAPK_gen_1	517	529	PF00069	0.499
DOC_MAPK_gen_1	650	657	PF00069	0.675
DOC_MAPK_MEF2A_6	522	529	PF00069	0.653
DOC_PP4_FxxP_1	536	539	PF00568	0.542
DOC_PP4_MxPP_1	300	303	PF00568	0.532
DOC_USP7_MATH_1	20	24	PF00917	0.586
DOC_USP7_MATH_1	484	488	PF00917	0.639
DOC_USP7_MATH_1	543	547	PF00917	0.684
DOC_USP7_MATH_1	671	675	PF00917	0.603
DOC_USP7_MATH_2	105	111	PF00917	0.558
DOC_USP7_MATH_2	119	125	PF00917	0.554
DOC_USP7_MATH_2	147	153	PF00917	0.583
DOC_USP7_MATH_2	161	167	PF00917	0.580
DOC_USP7_MATH_2	175	181	PF00917	0.582
DOC_USP7_MATH_2	188	194	PF00917	0.550
DOC_USP7_MATH_2	202	208	PF00917	0.551
DOC_USP7_MATH_2	216	222	PF00917	0.582
DOC_USP7_MATH_2	230	236	PF00917	0.574
DOC_USP7_MATH_2	49	55	PF00917	0.583
DOC_USP7_MATH_2	63	69	PF00917	0.566
DOC_USP7_MATH_2	91	97	PF00917	0.583
DOC_USP7_UBL2_3	505	509	PF12436	0.615
DOC_WW_Pin1_4	313	318	PF00397	0.674
DOC_WW_Pin1_4	323	328	PF00397	0.590
DOC_WW_Pin1_4	500	505	PF00397	0.558
DOC_WW_Pin1_4	527	532	PF00397	0.658
DOC_WW_Pin1_4	572	577	PF00397	0.699
DOC_WW_Pin1_4	582	587	PF00397	0.547
DOC_WW_Pin1_4	600	605	PF00397	0.523
DOC_WW_Pin1_4	621	626	PF00397	0.582
DOC_WW_Pin1_4	674	679	PF00397	0.556
LIG_14-3-3_CanoR_1	255	260	PF00244	0.544
LIG_14-3-3_CanoR_1	304	311	PF00244	0.585
LIG_14-3-3_CanoR_1	330	336	PF00244	0.592
LIG_14-3-3_CanoR_1	584	590	PF00244	0.599
LIG_14-3-3_CanoR_1	597	601	PF00244	0.671
LIG_14-3-3_CanoR_1	650	656	PF00244	0.543
LIG_APCC_ABBA_1	29	34	PF00400	0.596
LIG_BIR_III_2	573	577	PF00653	0.558
LIG_BIR_III_2	668	672	PF00653	0.566
LIG_BRCT_BRCA1_1	7	11	PF00533	0.702
LIG_CtBP_PxDLS_1	678	682	PF00389	0.532
LIG_FHA_1	254	260	PF00498	0.548
LIG_FHA_1	332	338	PF00498	0.537
LIG_FHA_1	367	373	PF00498	0.606
LIG_FHA_1	427	433	PF00498	0.567
LIG_FHA_1	440	446	PF00498	0.445
LIG_FHA_1	455	461	PF00498	0.456
LIG_FHA_1	642	648	PF00498	0.721
LIG_FHA_1	656	662	PF00498	0.675
LIG_FHA_1	695	701	PF00498	0.674
LIG_FHA_2	363	369	PF00498	0.529
LIG_FHA_2	702	708	PF00498	0.565
LIG_LIR_Apic_2	533	539	PF02991	0.540
LIG_LIR_Gen_1	725	736	PF02991	0.552
LIG_LIR_Nem_3	725	731	PF02991	0.548
LIG_PCNA_yPIPBox_3	301	315	PF02747	0.535
LIG_PDZ_Class_1	749	754	PF00595	0.517
LIG_SH2_NCK_1	724	728	PF00017	0.676
LIG_SH2_PTP2	415	418	PF00017	0.477
LIG_SH2_STAP1	724	728	PF00017	0.528
LIG_SH2_STAT3	283	286	PF00017	0.552
LIG_SH2_STAT5	336	339	PF00017	0.545
LIG_SH2_STAT5	415	418	PF00017	0.477
LIG_SH2_STAT5	463	466	PF00017	0.369
LIG_SH3_3	131	137	PF00018	0.576
LIG_SH3_3	311	317	PF00018	0.600
LIG_SH3_3	321	327	PF00018	0.668
LIG_SH3_3	75	81	PF00018	0.574
LIG_SH3_4	301	308	PF00018	0.534
LIG_SH3_CIN85_PxpxPR_1	572	577	PF14604	0.551
LIG_SUMO_SIM_anti_2	738	750	PF11976	0.529
LIG_SUMO_SIM_par_1	355	365	PF11976	0.537
LIG_SUMO_SIM_par_1	738	750	PF11976	0.529
LIG_TRAF2_1	100	103	PF00917	0.587
LIG_TRAF2_1	133	136	PF00917	0.574
LIG_TRAF2_1	142	145	PF00917	0.564
LIG_TRAF2_1	156	159	PF00917	0.586
LIG_TRAF2_1	170	173	PF00917	0.657
LIG_TRAF2_1	184	187	PF00917	0.573
LIG_TRAF2_1	296	299	PF00917	0.696
LIG_TRAF2_1	77	80	PF00917	0.606
LIG_TRAF2_1	86	89	PF00917	0.625
LIG_TYR_ITIM	413	418	PF00017	0.343
LIG_TYR_ITIM	726	731	PF00017	0.522
LIG_UBA3_1	460	469	PF00899	0.373
LIG_UBA3_1	520	526	PF00899	0.548
LIG_WW_3	301	305	PF00397	0.534
MOD_CDK_SPK_2	313	318	PF00069	0.674
MOD_CDK_SPK_2	323	328	PF00069	0.590
MOD_CDK_SPK_2	500	505	PF00069	0.558
MOD_CDK_SPK_2	527	532	PF00069	0.658
MOD_CDK_SPK_2	572	577	PF00069	0.551
MOD_CDK_SPxK_1	500	506	PF00069	0.556
MOD_CDK_SPxxK_3	323	330	PF00069	0.683
MOD_CDK_SPxxK_3	500	507	PF00069	0.553
MOD_CK1_1	253	259	PF00069	0.685
MOD_CK1_1	277	283	PF00069	0.701
MOD_CK1_1	331	337	PF00069	0.626
MOD_CK1_1	352	358	PF00069	0.712
MOD_CK1_1	4	10	PF00069	0.693
MOD_CK1_1	439	445	PF00069	0.434
MOD_CK1_1	473	479	PF00069	0.623
MOD_CK1_1	585	591	PF00069	0.678
MOD_CK1_1	627	633	PF00069	0.542
MOD_CK1_1	648	654	PF00069	0.693
MOD_CK1_1	674	680	PF00069	0.532
MOD_CK1_1	684	690	PF00069	0.517
MOD_CK1_1	729	735	PF00069	0.531
MOD_CK2_1	111	117	PF00069	0.719
MOD_CK2_1	125	131	PF00069	0.602
MOD_CK2_1	139	145	PF00069	0.627
MOD_CK2_1	153	159	PF00069	0.572
MOD_CK2_1	167	173	PF00069	0.675
MOD_CK2_1	181	187	PF00069	0.635
MOD_CK2_1	272	278	PF00069	0.650
MOD_CK2_1	293	299	PF00069	0.693
MOD_CK2_1	362	368	PF00069	0.531
MOD_CK2_1	381	387	PF00069	0.363
MOD_CK2_1	41	47	PF00069	0.615
MOD_CK2_1	55	61	PF00069	0.661
MOD_CK2_1	69	75	PF00069	0.628
MOD_CK2_1	701	707	PF00069	0.562
MOD_CK2_1	83	89	PF00069	0.732
MOD_CK2_1	97	103	PF00069	0.614
MOD_GlcNHglycan	274	277	PF01048	0.536
MOD_GlcNHglycan	330	333	PF01048	0.611
MOD_GlcNHglycan	338	341	PF01048	0.549
MOD_GlcNHglycan	344	347	PF01048	0.574
MOD_GlcNHglycan	472	475	PF01048	0.528
MOD_GlcNHglycan	486	489	PF01048	0.584
MOD_GlcNHglycan	626	629	PF01048	0.679
MOD_GlcNHglycan	683	686	PF01048	0.558
MOD_GSK3_1	1	8	PF00069	0.684
MOD_GSK3_1	103	110	PF00069	0.556
MOD_GSK3_1	117	124	PF00069	0.553
MOD_GSK3_1	145	152	PF00069	0.584
MOD_GSK3_1	159	166	PF00069	0.576
MOD_GSK3_1	173	180	PF00069	0.579
MOD_GSK3_1	186	193	PF00069	0.548
MOD_GSK3_1	20	27	PF00069	0.537
MOD_GSK3_1	200	207	PF00069	0.551
MOD_GSK3_1	214	221	PF00069	0.577
MOD_GSK3_1	228	235	PF00069	0.574
MOD_GSK3_1	242	249	PF00069	0.566
MOD_GSK3_1	250	257	PF00069	0.608
MOD_GSK3_1	326	333	PF00069	0.633
MOD_GSK3_1	33	40	PF00069	0.582
MOD_GSK3_1	348	355	PF00069	0.657
MOD_GSK3_1	362	369	PF00069	0.669
MOD_GSK3_1	426	433	PF00069	0.530
MOD_GSK3_1	435	442	PF00069	0.459
MOD_GSK3_1	47	54	PF00069	0.588
MOD_GSK3_1	580	587	PF00069	0.592
MOD_GSK3_1	596	603	PF00069	0.543
MOD_GSK3_1	61	68	PF00069	0.566
MOD_GSK3_1	624	631	PF00069	0.545
MOD_GSK3_1	641	648	PF00069	0.670
MOD_GSK3_1	651	658	PF00069	0.594
MOD_GSK3_1	677	684	PF00069	0.559
MOD_GSK3_1	692	699	PF00069	0.514
MOD_GSK3_1	726	733	PF00069	0.524
MOD_GSK3_1	745	752	PF00069	0.486
MOD_GSK3_1	89	96	PF00069	0.573
MOD_N-GLC_1	402	407	PF02516	0.469
MOD_N-GLC_1	566	571	PF02516	0.559
MOD_N-GLC_1	580	585	PF02516	0.668
MOD_NEK2_1	1	6	PF00069	0.613
MOD_NEK2_1	254	259	PF00069	0.614
MOD_NEK2_1	285	290	PF00069	0.616
MOD_NEK2_1	393	398	PF00069	0.454
MOD_NEK2_1	655	660	PF00069	0.540
MOD_NEK2_1	681	686	PF00069	0.696
MOD_PIKK_1	304	310	PF00454	0.689
MOD_PIKK_1	316	322	PF00454	0.568
MOD_PKA_2	14	20	PF00069	0.580
MOD_PKA_2	254	260	PF00069	0.548
MOD_PKA_2	342	348	PF00069	0.530
MOD_PKA_2	548	554	PF00069	0.579
MOD_PKA_2	596	602	PF00069	0.695
MOD_PKA_2	651	657	PF00069	0.666
MOD_PKB_1	328	336	PF00069	0.682
MOD_Plk_1	277	283	PF00069	0.701
MOD_Plk_1	348	354	PF00069	0.547
MOD_Plk_1	386	392	PF00069	0.354
MOD_Plk_1	543	549	PF00069	0.661
MOD_Plk_1	691	697	PF00069	0.539
MOD_Plk_1	718	724	PF00069	0.558
MOD_Plk_1	729	735	PF00069	0.508
MOD_Plk_2-3	293	299	PF00069	0.560
MOD_Plk_4	331	337	PF00069	0.540
MOD_Plk_4	548	554	PF00069	0.700
MOD_Plk_4	566	572	PF00069	0.531
MOD_Plk_4	585	591	PF00069	0.545
MOD_Plk_4	671	677	PF00069	0.537
MOD_ProDKin_1	313	319	PF00069	0.672
MOD_ProDKin_1	323	329	PF00069	0.590
MOD_ProDKin_1	500	506	PF00069	0.556
MOD_ProDKin_1	527	533	PF00069	0.659
MOD_ProDKin_1	572	578	PF00069	0.704
MOD_ProDKin_1	582	588	PF00069	0.546
MOD_ProDKin_1	600	606	PF00069	0.523
MOD_ProDKin_1	621	627	PF00069	0.582
MOD_ProDKin_1	674	680	PF00069	0.556
MOD_SUMO_for_1	419	422	PF00179	0.350
MOD_SUMO_rev_2	293	303	PF00179	0.550
MOD_SUMO_rev_2	443	450	PF00179	0.522
MOD_SUMO_rev_2	659	667	PF00179	0.620
TRG_DiLeu_BaEn_1	740	745	PF01217	0.531
TRG_ENDOCYTIC_2	415	418	PF00928	0.477
TRG_ENDOCYTIC_2	728	731	PF00928	0.547
TRG_ER_diArg_1	327	330	PF00400	0.682
TRG_ER_diArg_1	341	344	PF00400	0.548
TRG_ER_diArg_1	515	518	PF00400	0.495
TRG_ER_diArg_1	616	619	PF00400	0.619
TRG_NLS_MonoExtC_3	504	509	PF00514	0.685
TRG_NLS_MonoExtN_4	504	510	PF00514	0.680
TRG_Pf-PMV_PEXEL_1	304	308	PF00026	0.539
TRG_Pf-PMV_PEXEL_1	619	623	PF00026	0.618

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IF98	Leishmania donovani	37%	89%
A4I1E8	Leishmania infantum	37%	89%
E9AXI5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	80%
Q4Q9Y7	Leishmania major	38%	99%