Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HE35_LEIBR

TriTrypDb:

LbrM.25.0880 , LBRM2903_250017800

Length:

457

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HE35

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HE35

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	125	129	PF00656	0.870
CLV_C14_Caspase3-7	396	400	PF00656	0.716
CLV_NRD_NRD_1	118	120	PF00675	0.856
CLV_NRD_NRD_1	137	139	PF00675	0.560
CLV_NRD_NRD_1	171	173	PF00675	0.837
CLV_NRD_NRD_1	421	423	PF00675	0.745
CLV_PCSK_KEX2_1	118	120	PF00082	0.856
CLV_PCSK_KEX2_1	137	139	PF00082	0.560
CLV_PCSK_KEX2_1	171	173	PF00082	0.837
CLV_PCSK_KEX2_1	374	376	PF00082	0.680
CLV_PCSK_KEX2_1	427	429	PF00082	0.750
CLV_PCSK_PC1ET2_1	374	376	PF00082	0.680
CLV_PCSK_PC1ET2_1	427	429	PF00082	0.750
CLV_PCSK_SKI1_1	411	415	PF00082	0.706
CLV_PCSK_SKI1_1	440	444	PF00082	0.680
DEG_APCC_DBOX_1	17	25	PF00400	0.818
DEG_SCF_FBW7_1	70	77	PF00400	0.868
DEG_SPOP_SBC_1	309	313	PF00917	0.828
DOC_CKS1_1	281	286	PF01111	0.868
DOC_CYCLIN_yCln2_LP_2	100	106	PF00134	0.851
DOC_MAPK_MEF2A_6	318	326	PF00069	0.813
DOC_PP1_RVXF_1	117	124	PF00149	0.861
DOC_PP2B_LxvP_1	211	214	PF13499	0.844
DOC_PP2B_LxvP_1	78	81	PF13499	0.872
DOC_USP7_MATH_1	175	179	PF00917	0.828
DOC_USP7_MATH_1	302	306	PF00917	0.824
DOC_USP7_MATH_1	31	35	PF00917	0.822
DOC_USP7_MATH_1	96	100	PF00917	0.857
DOC_USP7_UBL2_3	423	427	PF12436	0.716
DOC_WW_Pin1_4	277	282	PF00397	0.871
DOC_WW_Pin1_4	6	11	PF00397	0.871
DOC_WW_Pin1_4	70	75	PF00397	0.865
DOC_WW_Pin1_4	76	81	PF00397	0.768
LIG_14-3-3_CanoR_1	183	191	PF00244	0.853
LIG_14-3-3_CanoR_1	223	228	PF00244	0.852
LIG_14-3-3_CanoR_1	350	357	PF00244	0.821
LIG_14-3-3_CanoR_1	407	413	PF00244	0.698
LIG_CtBP_PxDLS_1	14	18	PF00389	0.814
LIG_FHA_1	261	267	PF00498	0.848
LIG_FHA_1	293	299	PF00498	0.849
LIG_FHA_1	311	317	PF00498	0.506
LIG_FHA_1	321	327	PF00498	0.632
LIG_FHA_1	59	65	PF00498	0.881
LIG_FHA_1	73	79	PF00498	0.627
LIG_FHA_2	331	337	PF00498	0.692
LIG_FHA_2	439	445	PF00498	0.682
LIG_LIR_Apic_2	36	42	PF02991	0.846
LIG_LIR_Apic_2	360	365	PF02991	0.814
LIG_LIR_Gen_1	120	131	PF02991	0.866
LIG_LIR_Gen_1	218	229	PF02991	0.846
LIG_LIR_Gen_1	240	246	PF02991	0.856
LIG_LIR_Gen_1	342	347	PF02991	0.770
LIG_LIR_Gen_1	384	395	PF02991	0.663
LIG_LIR_Nem_3	120	126	PF02991	0.865
LIG_LIR_Nem_3	168	173	PF02991	0.841
LIG_LIR_Nem_3	218	224	PF02991	0.842
LIG_LIR_Nem_3	240	244	PF02991	0.856
LIG_LIR_Nem_3	342	346	PF02991	0.769
LIG_LIR_Nem_3	384	390	PF02991	0.661
LIG_PCNA_PIPBox_1	32	41	PF02747	0.835
LIG_PCNA_yPIPBox_3	27	39	PF02747	0.827
LIG_Rb_LxCxE_1	79	102	PF01857	0.870
LIG_SH2_CRK	221	225	PF00017	0.847
LIG_SH2_CRK	343	347	PF00017	0.767
LIG_SH2_CRK	362	366	PF00017	0.464
LIG_SH2_NCK_1	221	225	PF00017	0.847
LIG_SH2_NCK_1	362	366	PF00017	0.797
LIG_SH2_NCK_1	383	387	PF00017	0.655
LIG_SH2_STAP1	343	347	PF00017	0.767
LIG_SH2_STAP1	383	387	PF00017	0.655
LIG_SH2_STAT5	181	184	PF00017	0.854
LIG_SH2_STAT5	241	244	PF00017	0.858
LIG_SH2_STAT5	362	365	PF00017	0.804
LIG_SH2_STAT5	76	79	PF00017	0.875
LIG_SH3_2	52	57	PF14604	0.888
LIG_SH3_3	158	164	PF00018	0.843
LIG_SH3_3	278	284	PF00018	0.870
LIG_SH3_3	39	45	PF00018	0.863
LIG_SH3_3	49	55	PF00018	0.715
LIG_SH3_3	61	67	PF00018	0.672
LIG_SH3_3	90	96	PF00018	0.869
LIG_SH3_4	423	430	PF00018	0.723
LIG_SH3_4	54	61	PF00018	0.884
LIG_TRAF2_1	9	12	PF00917	0.862
LIG_TRAF2_2	235	240	PF00917	0.839
LIG_TRFH_1	76	80	PF08558	0.874
LIG_TYR_ITIM	341	346	PF00017	0.765
LIG_UBA3_1	100	108	PF00899	0.853
MOD_CDK_SPK_2	280	285	PF00069	0.871
MOD_CK1_1	184	190	PF00069	0.851
MOD_CK1_1	193	199	PF00069	0.716
MOD_CK1_1	280	286	PF00069	0.868
MOD_CK1_1	296	302	PF00069	0.556
MOD_CK1_1	450	456	PF00069	0.728
MOD_CK2_1	193	199	PF00069	0.874
MOD_CK2_1	330	336	PF00069	0.688
MOD_CK2_1	426	432	PF00069	0.736
MOD_CK2_1	438	444	PF00069	0.469
MOD_CK2_1	5	11	PF00069	0.873
MOD_CK2_1	96	102	PF00069	0.856
MOD_GlcNHglycan	142	145	PF01048	0.875
MOD_GlcNHglycan	217	220	PF01048	0.831
MOD_GlcNHglycan	295	298	PF01048	0.849
MOD_GlcNHglycan	304	307	PF01048	0.671
MOD_GlcNHglycan	333	336	PF01048	0.780
MOD_GlcNHglycan	352	355	PF01048	0.492
MOD_GlcNHglycan	365	368	PF01048	0.544
MOD_GSK3_1	1	8	PF00069	0.878
MOD_GSK3_1	136	143	PF00069	0.884
MOD_GSK3_1	177	184	PF00069	0.843
MOD_GSK3_1	186	193	PF00069	0.700
MOD_GSK3_1	240	247	PF00069	0.853
MOD_GSK3_1	288	295	PF00069	0.854
MOD_GSK3_1	316	323	PF00069	0.815
MOD_GSK3_1	342	349	PF00069	0.778
MOD_GSK3_1	70	77	PF00069	0.868
MOD_N-GLC_1	184	189	PF02516	0.848
MOD_N-GLC_1	360	365	PF02516	0.814
MOD_NEK2_1	1	6	PF00069	0.878
MOD_NEK2_1	133	138	PF00069	0.890
MOD_NEK2_1	215	220	PF00069	0.836
MOD_NEK2_1	244	249	PF00069	0.845
MOD_NEK2_1	308	313	PF00069	0.829
MOD_NEK2_1	322	327	PF00069	0.562
MOD_NEK2_1	330	335	PF00069	0.627
MOD_NEK2_1	346	351	PF00069	0.588
MOD_PIKK_1	186	192	PF00454	0.857
MOD_PIKK_1	233	239	PF00454	0.837
MOD_PKA_2	136	142	PF00069	0.885
MOD_PKA_2	215	221	PF00069	0.838
MOD_PKA_2	222	228	PF00069	0.728
MOD_PKA_2	381	387	PF00069	0.663
MOD_PKA_2	406	412	PF00069	0.694
MOD_PKA_2	450	456	PF00069	0.728
MOD_PKB_1	348	356	PF00069	0.817
MOD_Plk_1	447	453	PF00069	0.695
MOD_Plk_1	96	102	PF00069	0.856
MOD_Plk_2-3	432	438	PF00069	0.713
MOD_Plk_4	177	183	PF00069	0.843
MOD_Plk_4	223	229	PF00069	0.853
MOD_Plk_4	240	246	PF00069	0.559
MOD_Plk_4	438	444	PF00069	0.679
MOD_Plk_4	96	102	PF00069	0.856
MOD_ProDKin_1	277	283	PF00069	0.870
MOD_ProDKin_1	6	12	PF00069	0.869
MOD_ProDKin_1	70	76	PF00069	0.867
MOD_SUMO_rev_2	418	425	PF00179	0.726
MOD_SUMO_rev_2	432	441	PF00179	0.460
TRG_ENDOCYTIC_2	221	224	PF00928	0.850
TRG_ENDOCYTIC_2	241	244	PF00928	0.508
TRG_ENDOCYTIC_2	343	346	PF00928	0.765
TRG_ENDOCYTIC_2	387	390	PF00928	0.661
TRG_ER_diArg_1	170	172	PF00400	0.839
TRG_Pf-PMV_PEXEL_1	440	444	PF00026	0.680