ANK_REP_REGION domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4HE14_LEIBR

TriTrypDb:

LbrM.25.0670 , LBRM2903_250015600

Length:

1049

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

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Expansion

Sequence features

A4HE14

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HE14

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	294	298	PF00656	0.637
CLV_C14_Caspase3-7	689	693	PF00656	0.688
CLV_C14_Caspase3-7	706	710	PF00656	0.586
CLV_C14_Caspase3-7	810	814	PF00656	0.783
CLV_NRD_NRD_1	1038	1040	PF00675	0.548
CLV_NRD_NRD_1	128	130	PF00675	0.278
CLV_NRD_NRD_1	263	265	PF00675	0.575
CLV_NRD_NRD_1	545	547	PF00675	0.401
CLV_NRD_NRD_1	665	667	PF00675	0.474
CLV_NRD_NRD_1	776	778	PF00675	0.491

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P736	Leptomonas seymouri	39%	88%
A0A3S5H7E4	Leishmania donovani	65%	90%
A4I1C1	Leishmania infantum	65%	90%
E9AXF7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	64%	90%
Q4QA15	Leishmania major	65%	100%

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