Hydrolase_4 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4HE01_LEIBR

TriTrypDb:

LbrM.25.0540 , LBRM2903_250014200

Length:

388

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HE01

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HE01

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	17	19	PF00675	0.717
CLV_NRD_NRD_1	183	185	PF00675	0.875
CLV_NRD_NRD_1	301	303	PF00675	0.780
CLV_NRD_NRD_1	369	371	PF00675	0.862
CLV_PCSK_KEX2_1	16	18	PF00082	0.721
CLV_PCSK_KEX2_1	301	303	PF00082	0.780
CLV_PCSK_PC7_1	13	19	PF00082	0.709
DOC_ANK_TNKS_1	70	77	PF00023	0.838
DOC_CDC14_PxL_1	294	302	PF14671	0.757
DOC_CYCLIN_RxL_1	76	87	PF00134	0.833
DOC_MAPK_gen_1	13	21	PF00069	0.710
DOC_PP2B_LxvP_1	162	165	PF13499	0.789
DOC_PP2B_LxvP_1	245	248	PF13499	0.726
DOC_PP2B_LxvP_1	66	69	PF13499	0.834
DOC_PP4_FxxP_1	195	198	PF00568	0.813
DOC_USP7_MATH_1	110	114	PF00917	0.841
DOC_USP7_MATH_1	173	177	PF00917	0.821
DOC_USP7_MATH_1	196	200	PF00917	0.805
DOC_USP7_MATH_1	48	52	PF00917	0.819
DOC_USP7_MATH_1	58	62	PF00917	0.656
DOC_USP7_MATH_1	67	71	PF00917	0.502
DOC_USP7_MATH_1	77	81	PF00917	0.523
DOC_USP7_MATH_1	85	89	PF00917	0.475
LIG_14-3-3_CanoR_1	184	192	PF00244	0.849
LIG_14-3-3_CanoR_1	26	32	PF00244	0.800
LIG_14-3-3_CanoR_1	315	319	PF00244	0.756
LIG_BIR_II_1	1	5	PF00653	0.714
LIG_BRCT_BRCA1_1	127	131	PF00533	0.728
LIG_BRCT_BRCA1_1	207	211	PF00533	0.768
LIG_Clathr_ClatBox_1	202	206	PF01394	0.796
LIG_Clathr_ClatBox_1	214	218	PF01394	0.511
LIG_EVH1_2	191	195	PF00568	0.823
LIG_FHA_1	178	184	PF00498	0.865
LIG_FHA_1	231	237	PF00498	0.698
LIG_FHA_1	239	245	PF00498	0.575
LIG_FHA_1	247	253	PF00498	0.447
LIG_FHA_1	282	288	PF00498	0.763
LIG_FHA_1	358	364	PF00498	0.876
LIG_FHA_1	52	58	PF00498	0.822
LIG_FHA_1	63	69	PF00498	0.639
LIG_FHA_1	85	91	PF00498	0.790
LIG_LIR_Gen_1	128	138	PF02991	0.736
LIG_LIR_Gen_1	142	152	PF02991	0.522
LIG_LIR_Gen_1	166	173	PF02991	0.813
LIG_LIR_Gen_1	208	219	PF02991	0.736
LIG_LIR_Nem_3	128	134	PF02991	0.722
LIG_LIR_Nem_3	142	147	PF02991	0.516
LIG_LIR_Nem_3	166	172	PF02991	0.811
LIG_LIR_Nem_3	208	214	PF02991	0.754
LIG_Pex14_1	201	205	PF04695	0.794
LIG_Pex14_2	131	135	PF04695	0.723
LIG_Rb_LxCxE_1	133	149	PF01857	0.761
LIG_SH2_STAP1	31	35	PF00017	0.793
LIG_SH2_STAT5	213	216	PF00017	0.727
LIG_SH2_STAT5	270	273	PF00017	0.743
LIG_SH3_3	167	173	PF00018	0.813
LIG_SH3_3	41	47	PF00018	0.797
LIG_SUMO_SIM_anti_2	233	239	PF11976	0.674
LIG_SUMO_SIM_anti_2	243	249	PF11976	0.555
LIG_SUMO_SIM_anti_2	293	298	PF11976	0.747
LIG_SUMO_SIM_par_1	243	249	PF11976	0.730
LIG_SUMO_SIM_par_1	250	256	PF11976	0.588
MOD_CK1_1	101	107	PF00069	0.855
MOD_CK1_1	133	139	PF00069	0.755
MOD_CK1_1	351	357	PF00069	0.867
MOD_CK1_1	381	387	PF00069	0.853
MOD_CK1_1	51	57	PF00069	0.823
MOD_CK1_1	61	67	PF00069	0.659
MOD_CK2_1	33	39	PF00069	0.782
MOD_GlcNHglycan	100	103	PF01048	0.841
MOD_GlcNHglycan	225	229	PF01048	0.724
MOD_GlcNHglycan	329	333	PF01048	0.832
MOD_GlcNHglycan	338	341	PF01048	0.695
MOD_GlcNHglycan	380	383	PF01048	0.869
MOD_GlcNHglycan	50	53	PF01048	0.820
MOD_GlcNHglycan	60	63	PF01048	0.661
MOD_GSK3_1	142	149	PF00069	0.763
MOD_GSK3_1	173	180	PF00069	0.832
MOD_GSK3_1	248	255	PF00069	0.712
MOD_GSK3_1	310	317	PF00069	0.772
MOD_GSK3_1	328	335	PF00069	0.518
MOD_GSK3_1	336	343	PF00069	0.710
MOD_GSK3_1	348	355	PF00069	0.517
MOD_GSK3_1	58	65	PF00069	0.831
MOD_GSK3_1	85	92	PF00069	0.791
MOD_NEK2_1	12	17	PF00069	0.703
MOD_NEK2_1	205	210	PF00069	0.782
MOD_NEK2_1	281	286	PF00069	0.753
MOD_NEK2_1	310	315	PF00069	0.778
MOD_NEK2_1	350	355	PF00069	0.779
MOD_NEK2_1	83	88	PF00069	0.804
MOD_NEK2_2	207	212	PF00069	0.765
MOD_PIKK_1	238	244	PF00454	0.702
MOD_PIKK_1	353	359	PF00454	0.870
MOD_PIKK_1	51	57	PF00454	0.823
MOD_PIKK_1	85	91	PF00454	0.790
MOD_PK_1	231	237	PF00069	0.698
MOD_PKA_1	325	331	PF00069	0.817
MOD_PKA_2	12	18	PF00069	0.705
MOD_PKA_2	183	189	PF00069	0.863
MOD_PKA_2	314	320	PF00069	0.760
MOD_PKA_2	348	354	PF00069	0.827
MOD_PKA_2	357	363	PF00069	0.756
MOD_Plk_1	310	316	PF00069	0.775
MOD_Plk_1	33	39	PF00069	0.782
MOD_Plk_1	77	83	PF00069	0.850
MOD_Plk_2-3	364	370	PF00069	0.869
MOD_Plk_4	125	131	PF00069	0.742
MOD_Plk_4	197	203	PF00069	0.801
MOD_Plk_4	231	237	PF00069	0.698
MOD_Plk_4	89	95	PF00069	0.803
MOD_SUMO_rev_2	364	372	PF00179	0.864
MOD_SUMO_rev_2	78	86	PF00179	0.834
TRG_DiLeu_BaEn_2	224	230	PF01217	0.709
TRG_ENDOCYTIC_2	213	216	PF00928	0.727
TRG_ENDOCYTIC_2	270	273	PF00928	0.743
TRG_ER_diArg_1	16	18	PF00400	0.721
TRG_ER_diArg_1	300	302	PF00400	0.779
TRG_NES_CRM1_1	309	324	PF08389	0.774
TRG_Pf-PMV_PEXEL_1	304	309	PF00026	0.792