LeishMANIAdb
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Cell division protein FtsI

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Cell division protein FtsI
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HDV7_LEIBR
TriTrypDb:
LbrM.25.0100 , LBRM2903_250006200
Length:
71

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
Term Name Level Count
GO:0016020 membrane 2 6
GO:0110165 cellular anatomical entity 1 6

Expansion

Sequence features

A4HDV7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HDV7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 28 30 PF00675 0.462
CLV_NRD_NRD_1 68 70 PF00675 0.559
CLV_PCSK_KEX2_1 27 29 PF00082 0.457
CLV_PCSK_KEX2_1 68 70 PF00082 0.606
CLV_PCSK_PC1ET2_1 27 29 PF00082 0.359
DOC_CKS1_1 1 6 PF01111 0.563
DOC_MAPK_gen_1 12 20 PF00069 0.564
DOC_PP1_RVXF_1 39 46 PF00149 0.411
DOC_WW_Pin1_4 63 68 PF00397 0.393
LIG_14-3-3_CanoR_1 19 26 PF00244 0.606
LIG_BIR_II_1 1 5 PF00653 0.562
LIG_BIR_III_1 1 5 PF00653 0.565
LIG_BIR_III_3 1 5 PF00653 0.565
LIG_FHA_1 1 7 PF00498 0.653
LIG_PTB_Apo_2 55 62 PF02174 0.308
LIG_SH2_STAT5 60 63 PF00017 0.476
LIG_SH3_3 61 67 PF00018 0.316
LIG_SUMO_SIM_anti_2 46 52 PF11976 0.308
LIG_SUMO_SIM_par_1 48 55 PF11976 0.377
LIG_SxIP_EBH_1 35 45 PF03271 0.512
MOD_CDC14_SPxK_1 66 69 PF00782 0.344
MOD_CDK_SPK_2 63 68 PF00069 0.393
MOD_CDK_SPxK_1 63 69 PF00069 0.334
MOD_CMANNOS 42 45 PF00535 0.308
MOD_GlcNHglycan 36 39 PF01048 0.427
MOD_GSK3_1 59 66 PF00069 0.465
MOD_NEK2_1 43 48 PF00069 0.308
MOD_PKA_2 18 24 PF00069 0.610
MOD_Plk_4 52 58 PF00069 0.320
MOD_ProDKin_1 63 69 PF00069 0.396
MOD_SUMO_rev_2 21 26 PF00179 0.615
MOD_SUMO_rev_2 30 37 PF00179 0.621
TRG_ENDOCYTIC_2 60 63 PF00928 0.473
TRG_ER_diArg_1 67 69 PF00400 0.348
TRG_ER_diArg_1 9 12 PF00400 0.617

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I205 Leptomonas seymouri 63% 100%
A0A3S7WYU2 Leishmania donovani 74% 100%
A4I152 Leishmania infantum 75% 100%
E9AX86 Leishmania mexicana (strain MHOM/GT/2001/U1103) 71% 100%
Q4QA86 Leishmania major 75% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS