Coiled-coil domain-containing protein 153

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HDU2_LEIBR

TriTrypDb:

LbrM.24.2390 , LBRM2903_240031500

Length:

163


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005930	axoneme	2	1
GO:0110165	cellular anatomical entity	1	1

A4HDU2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HDU2


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	112	114	PF00675	0.397
CLV_PCSK_KEX2_1	112	114	PF00082	0.362
CLV_PCSK_KEX2_1	134	136	PF00082	0.495
CLV_PCSK_PC1ET2_1	112	114	PF00082	0.362
CLV_PCSK_PC1ET2_1	134	136	PF00082	0.495
CLV_PCSK_SKI1_1	65	69	PF00082	0.483
DOC_MAPK_gen_1	85	95	PF00069	0.390
DOC_USP7_UBL2_3	72	76	PF12436	0.603
LIG_14-3-3_CanoR_1	143	151	PF00244	0.405
LIG_Actin_WH2_2	23	40	PF00022	0.456
LIG_BRCT_BRCA1_1	122	126	PF00533	0.309
LIG_CaM_IQ_9	105	120	PF13499	0.446
LIG_FHA_1	64	70	PF00498	0.396
LIG_FHA_2	143	149	PF00498	0.316
LIG_LIR_Gen_1	136	142	PF02991	0.412
LIG_LIR_Nem_3	136	140	PF02991	0.413
LIG_SH2_STAT3	18	21	PF00017	0.541
LIG_SH2_STAT5	41	44	PF00017	0.511
LIG_SH3_3	157	163	PF00018	0.374
LIG_SUMO_SIM_anti_2	25	32	PF11976	0.460
LIG_SUMO_SIM_par_1	25	32	PF11976	0.506
LIG_TRAF2_1	107	110	PF00917	0.424
MOD_CK2_1	136	142	PF00069	0.492
MOD_CK2_1	153	159	PF00069	0.418
MOD_Cter_Amidation	70	73	PF01082	0.332
MOD_GlcNHglycan	122	125	PF01048	0.404
MOD_GlcNHglycan	58	61	PF01048	0.528
MOD_GSK3_1	125	132	PF00069	0.563
MOD_GSK3_1	6	13	PF00069	0.604
MOD_NEK2_1	80	85	PF00069	0.495
MOD_PKA_1	6	12	PF00069	0.507
MOD_PKA_2	142	148	PF00069	0.406
MOD_Plk_1	63	69	PF00069	0.570
MOD_Plk_1	81	87	PF00069	0.294
MOD_Plk_2-3	136	142	PF00069	0.523
MOD_SUMO_rev_2	64	74	PF00179	0.347
TRG_DiLeu_BaEn_1	150	155	PF01217	0.487
TRG_DiLeu_BaEn_1	64	69	PF01217	0.322
TRG_NES_CRM1_1	32	43	PF08389	0.499
TRG_NLS_MonoExtC_3	111	117	PF00514	0.538
TRG_Pf-PMV_PEXEL_1	113	117	PF00026	0.376
TRG_Pf-PMV_PEXEL_1	46	50	PF00026	0.357


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCM4	Leptomonas seymouri	59%	100%
A0A1X0NW82	Trypanosomatidae	36%	95%
A0A3Q8ICA5	Leishmania donovani	75%	100%
A0A422N6N3	Trypanosoma rangeli	31%	94%
A4I139	Leishmania infantum	75%	100%
C9ZW69	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	99%
E9AX77	Leishmania mexicana (strain MHOM/GT/2001/U1103)	73%	100%
Q4QA99	Leishmania major	76%	100%