Phosphatidylinositol 3-kinase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

phosphatidylinositol 3-kinase, putative

Species:

Leishmania braziliensis

UniProt:

A4HDR3_LEIBR

TriTrypDb:

LbrM.24.2090 , LBRM2903_240028600

Length:

1089

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0000407	phagophore assembly site	2	1
GO:0005737	cytoplasm	2	1
GO:0005768	endosome	7	1
GO:0005777	peroxisome	6	1
GO:0005942	phosphatidylinositol 3-kinase complex	3	1
GO:0016020	membrane	2	1
GO:0031410	cytoplasmic vesicle	6	1
GO:0031982	vesicle	4	1
GO:0032991	protein-containing complex	1	1
GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I	5	1
GO:0034272	phosphatidylinositol 3-kinase complex, class III, type II	5	1
GO:0035032	phosphatidylinositol 3-kinase complex, class III	4	1
GO:0042579	microbody	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0061695	transferase complex, transferring phosphorus-containing groups	4	1
GO:0097708	intracellular vesicle	5	1
GO:0098796	membrane protein complex	2	1
GO:0110165	cellular anatomical entity	1	1
GO:1902494	catalytic complex	2	1
GO:1990234	transferase complex	3	1

Expansion

Sequence features

A4HDR3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HDR3

Function

Biological processes
Term	Name	Level	Count
GO:0006793	phosphorus metabolic process	3	8
GO:0006796	phosphate-containing compound metabolic process	4	8
GO:0007165	signal transduction	2	8
GO:0008152	metabolic process	1	8
GO:0009987	cellular process	1	8
GO:0016310	phosphorylation	5	8
GO:0035556	intracellular signal transduction	3	8
GO:0044237	cellular metabolic process	2	8
GO:0048015	phosphatidylinositol-mediated signaling	5	8
GO:0048017	inositol lipid-mediated signaling	4	8
GO:0050789	regulation of biological process	2	8
GO:0050794	regulation of cellular process	3	8
GO:0065007	biological regulation	1	8
GO:0000045	autophagosome assembly	6	1
GO:0006629	lipid metabolic process	3	2
GO:0006644	phospholipid metabolic process	4	2
GO:0006650	glycerophospholipid metabolic process	5	2
GO:0006661	phosphatidylinositol biosynthetic process	6	2
GO:0006810	transport	3	1
GO:0006897	endocytosis	5	1
GO:0006914	autophagy	3	1
GO:0006996	organelle organization	4	1
GO:0007033	vacuole organization	5	1
GO:0008610	lipid biosynthetic process	4	2
GO:0008654	phospholipid biosynthetic process	5	2
GO:0009056	catabolic process	2	1
GO:0009058	biosynthetic process	2	2
GO:0016043	cellular component organization	3	1
GO:0016192	vesicle-mediated transport	4	1
GO:0019637	organophosphate metabolic process	3	2
GO:0022607	cellular component assembly	4	1
GO:0030242	autophagy of peroxisome	4	1
GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	8	1
GO:0044238	primary metabolic process	2	2
GO:0044248	cellular catabolic process	3	1
GO:0044249	cellular biosynthetic process	3	2
GO:0044255	cellular lipid metabolic process	3	2
GO:0045017	glycerolipid biosynthetic process	4	2
GO:0046474	glycerophospholipid biosynthetic process	5	2
GO:0046486	glycerolipid metabolic process	4	2
GO:0046488	phosphatidylinositol metabolic process	6	2
GO:0046854	phosphatidylinositol phosphate biosynthetic process	7	2
GO:0051179	localization	1	1
GO:0051234	establishment of localization	2	1
GO:0061919	process utilizing autophagic mechanism	2	1
GO:0070925	organelle assembly	5	1
GO:0071704	organic substance metabolic process	2	2
GO:0071840	cellular component organization or biogenesis	2	1
GO:0090407	organophosphate biosynthetic process	4	2
GO:1901576	organic substance biosynthetic process	3	2
GO:1905037	autophagosome organization	6	1

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	8
GO:0016301	kinase activity	4	8
GO:0016303	1-phosphatidylinositol-3-kinase activity	6	7
GO:0016740	transferase activity	2	8
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	8
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	7
GO:0035004	phosphatidylinositol 3-kinase activity	5	7
GO:0052742	phosphatidylinositol kinase activity	5	7
GO:0000166	nucleotide binding	3	1
GO:0005488	binding	1	1
GO:0005524	ATP binding	5	1
GO:0017076	purine nucleotide binding	4	1
GO:0030554	adenyl nucleotide binding	5	1
GO:0032553	ribonucleotide binding	3	1
GO:0032555	purine ribonucleotide binding	4	1
GO:0032559	adenyl ribonucleotide binding	5	1
GO:0035639	purine ribonucleoside triphosphate binding	4	1
GO:0036094	small molecule binding	2	1
GO:0043167	ion binding	2	1
GO:0043168	anion binding	3	1
GO:0097159	organic cyclic compound binding	2	1
GO:0097367	carbohydrate derivative binding	2	1
GO:1901265	nucleoside phosphate binding	3	1
GO:1901363	heterocyclic compound binding	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	294	298	PF00656	0.632
CLV_C14_Caspase3-7	644	648	PF00656	0.755
CLV_C14_Caspase3-7	666	670	PF00656	0.567
CLV_NRD_NRD_1	1007	1009	PF00675	0.430
CLV_NRD_NRD_1	244	246	PF00675	0.762
CLV_NRD_NRD_1	354	356	PF00675	0.651
CLV_NRD_NRD_1	418	420	PF00675	0.430
CLV_NRD_NRD_1	458	460	PF00675	0.486
CLV_NRD_NRD_1	517	519	PF00675	0.555
CLV_NRD_NRD_1	542	544	PF00675	0.564
CLV_NRD_NRD_1	615	617	PF00675	0.821
CLV_NRD_NRD_1	796	798	PF00675	0.573
CLV_PCSK_KEX2_1	244	246	PF00082	0.770
CLV_PCSK_KEX2_1	354	356	PF00082	0.651
CLV_PCSK_KEX2_1	418	420	PF00082	0.376
CLV_PCSK_KEX2_1	516	518	PF00082	0.534
CLV_PCSK_KEX2_1	542	544	PF00082	0.564
CLV_PCSK_KEX2_1	615	617	PF00082	0.821
CLV_PCSK_SKI1_1	182	186	PF00082	0.394
CLV_PCSK_SKI1_1	399	403	PF00082	0.413
CLV_PCSK_SKI1_1	430	434	PF00082	0.473
CLV_PCSK_SKI1_1	602	606	PF00082	0.483
CLV_PCSK_SKI1_1	745	749	PF00082	0.548
CLV_PCSK_SKI1_1	900	904	PF00082	0.376
CLV_Separin_Metazoa	914	918	PF03568	0.430
DEG_APCC_DBOX_1	1037	1045	PF00400	0.473
DEG_APCC_DBOX_1	345	353	PF00400	0.513
DEG_APCC_DBOX_1	44	52	PF00400	0.619
DEG_APCC_DBOX_1	899	907	PF00400	0.430
DEG_MDM2_SWIB_1	1073	1080	PF02201	0.544
DEG_SPOP_SBC_1	198	202	PF00917	0.514
DOC_CDC14_PxL_1	217	225	PF14671	0.697
DOC_CKS1_1	783	788	PF01111	0.778
DOC_CKS1_1	870	875	PF01111	0.557
DOC_CYCLIN_RxL_1	563	573	PF00134	0.539
DOC_CYCLIN_yCln2_LP_2	137	143	PF00134	0.607
DOC_MAPK_DCC_7	677	686	PF00069	0.540
DOC_MAPK_gen_1	1008	1015	PF00069	0.430
DOC_MAPK_gen_1	354	360	PF00069	0.631
DOC_MAPK_gen_1	396	404	PF00069	0.378
DOC_MAPK_gen_1	45	53	PF00069	0.609
DOC_MAPK_gen_1	677	686	PF00069	0.540
DOC_MAPK_gen_1	707	716	PF00069	0.775
DOC_MAPK_gen_1	745	755	PF00069	0.549
DOC_MAPK_gen_1	976	984	PF00069	0.430
DOC_MAPK_MEF2A_6	1008	1017	PF00069	0.376
DOC_MAPK_MEF2A_6	1043	1052	PF00069	0.482
DOC_MAPK_MEF2A_6	281	290	PF00069	0.508
DOC_MAPK_MEF2A_6	677	686	PF00069	0.540
DOC_MAPK_MEF2A_6	748	755	PF00069	0.497
DOC_MAPK_MEF2A_6	846	854	PF00069	0.419
DOC_MAPK_MEF2A_6	864	871	PF00069	0.439
DOC_MAPK_NFAT4_5	864	872	PF00069	0.467
DOC_PP1_RVXF_1	383	389	PF00149	0.430
DOC_PP1_RVXF_1	404	411	PF00149	0.376
DOC_PP2B_LxvP_1	264	267	PF13499	0.589
DOC_PP2B_LxvP_1	679	682	PF13499	0.530
DOC_PP4_FxxP_1	274	277	PF00568	0.695
DOC_PP4_FxxP_1	57	60	PF00568	0.405
DOC_PP4_FxxP_1	971	974	PF00568	0.376
DOC_PP4_MxPP_1	216	219	PF00568	0.622
DOC_USP7_MATH_1	191	195	PF00917	0.598
DOC_USP7_MATH_1	280	284	PF00917	0.769
DOC_USP7_MATH_1	325	329	PF00917	0.649
DOC_USP7_MATH_1	628	632	PF00917	0.696
DOC_USP7_MATH_1	791	795	PF00917	0.800
DOC_USP7_UBL2_3	1043	1047	PF12436	0.465
DOC_USP7_UBL2_3	592	596	PF12436	0.527
DOC_WW_Pin1_4	105	110	PF00397	0.556
DOC_WW_Pin1_4	184	189	PF00397	0.412
DOC_WW_Pin1_4	254	259	PF00397	0.559
DOC_WW_Pin1_4	56	61	PF00397	0.653
DOC_WW_Pin1_4	692	697	PF00397	0.759
DOC_WW_Pin1_4	775	780	PF00397	0.733
DOC_WW_Pin1_4	782	787	PF00397	0.636
DOC_WW_Pin1_4	869	874	PF00397	0.476
DOC_WW_Pin1_4	91	96	PF00397	0.519
LIG_14-3-3_CanoR_1	1008	1014	PF00244	0.330
LIG_14-3-3_CanoR_1	182	187	PF00244	0.606
LIG_14-3-3_CanoR_1	244	254	PF00244	0.718
LIG_14-3-3_CanoR_1	281	289	PF00244	0.745
LIG_14-3-3_CanoR_1	47	52	PF00244	0.534
LIG_14-3-3_CanoR_1	583	593	PF00244	0.529
LIG_14-3-3_CanoR_1	709	717	PF00244	0.644
LIG_14-3-3_CanoR_1	891	896	PF00244	0.350
LIG_14-3-3_CanoR_1	907	916	PF00244	0.412
LIG_14-3-3_CanoR_1	922	928	PF00244	0.322
LIG_Actin_WH2_2	746	761	PF00022	0.535
LIG_BIR_III_4	653	657	PF00653	0.825
LIG_BRCT_BRCA1_1	440	444	PF00533	0.376
LIG_BRCT_BRCA1_1	989	993	PF00533	0.430
LIG_Clathr_ClatBox_1	507	511	PF01394	0.501
LIG_Clathr_ClatBox_1	86	90	PF01394	0.641
LIG_Clathr_ClatBox_1	955	959	PF01394	0.376
LIG_deltaCOP1_diTrp_1	134	139	PF00928	0.472
LIG_deltaCOP1_diTrp_1	20	31	PF00928	0.745
LIG_EH1_1	565	573	PF00400	0.579
LIG_FHA_1	1056	1062	PF00498	0.500
LIG_FHA_1	223	229	PF00498	0.684
LIG_FHA_1	261	267	PF00498	0.503
LIG_FHA_1	268	274	PF00498	0.598
LIG_FHA_1	328	334	PF00498	0.641
LIG_FHA_1	362	368	PF00498	0.628
LIG_FHA_1	382	388	PF00498	0.430
LIG_FHA_1	63	69	PF00498	0.749
LIG_FHA_1	70	76	PF00498	0.650
LIG_FHA_1	732	738	PF00498	0.566
LIG_FHA_1	81	87	PF00498	0.424
LIG_FHA_1	830	836	PF00498	0.556
LIG_FHA_1	891	897	PF00498	0.366
LIG_FHA_1	910	916	PF00498	0.446
LIG_FHA_1	932	938	PF00498	0.376
LIG_FHA_2	120	126	PF00498	0.733
LIG_FHA_2	129	135	PF00498	0.478
LIG_FHA_2	31	37	PF00498	0.631
LIG_Integrin_RGD_1	292	294	PF01839	0.569
LIG_LIR_Apic_2	271	277	PF02991	0.671
LIG_LIR_Apic_2	397	403	PF02991	0.376
LIG_LIR_Apic_2	55	60	PF02991	0.396
LIG_LIR_Gen_1	1002	1011	PF02991	0.376
LIG_LIR_Gen_1	1071	1080	PF02991	0.532
LIG_LIR_Gen_1	134	143	PF02991	0.483
LIG_LIR_Gen_1	309	319	PF02991	0.637
LIG_LIR_Gen_1	441	450	PF02991	0.399
LIG_LIR_Gen_1	502	513	PF02991	0.404
LIG_LIR_Gen_1	754	763	PF02991	0.655
LIG_LIR_Gen_1	893	903	PF02991	0.319
LIG_LIR_Gen_1	990	999	PF02991	0.376
LIG_LIR_Nem_3	1002	1007	PF02991	0.376
LIG_LIR_Nem_3	1071	1076	PF02991	0.514
LIG_LIR_Nem_3	134	139	PF02991	0.467
LIG_LIR_Nem_3	21	27	PF02991	0.762
LIG_LIR_Nem_3	309	314	PF02991	0.646
LIG_LIR_Nem_3	441	447	PF02991	0.357
LIG_LIR_Nem_3	502	508	PF02991	0.346
LIG_LIR_Nem_3	754	758	PF02991	0.493
LIG_LIR_Nem_3	872	877	PF02991	0.483
LIG_LIR_Nem_3	893	898	PF02991	0.560
LIG_LIR_Nem_3	924	930	PF02991	0.430
LIG_LIR_Nem_3	959	963	PF02991	0.376
LIG_LIR_Nem_3	990	996	PF02991	0.376
LIG_MLH1_MIPbox_1	440	444	PF16413	0.376
LIG_NRBOX	1014	1020	PF00104	0.376
LIG_NRBOX	348	354	PF00104	0.565
LIG_PCNA_PIPBox_1	899	908	PF02747	0.430
LIG_PCNA_yPIPBox_3	558	569	PF02747	0.582
LIG_PCNA_yPIPBox_3	899	907	PF02747	0.376
LIG_PCNA_yPIPBox_3	976	985	PF02747	0.430
LIG_Pex14_2	1073	1077	PF04695	0.538
LIG_Pex14_2	132	136	PF04695	0.551
LIG_REV1ctd_RIR_1	311	319	PF16727	0.646
LIG_SH2_CRK	1004	1008	PF00017	0.376
LIG_SH2_CRK	27	31	PF00017	0.728
LIG_SH2_CRK	505	509	PF00017	0.404
LIG_SH2_CRK	874	878	PF00017	0.422
LIG_SH2_CRK	930	934	PF00017	0.376
LIG_SH2_NCK_1	103	107	PF00017	0.658
LIG_SH2_NCK_1	171	175	PF00017	0.654
LIG_SH2_NCK_1	27	31	PF00017	0.679
LIG_SH2_NCK_1	37	41	PF00017	0.564
LIG_SH2_NCK_1	479	483	PF00017	0.430
LIG_SH2_SRC	265	268	PF00017	0.617
LIG_SH2_STAP1	103	107	PF00017	0.586
LIG_SH2_STAP1	453	457	PF00017	0.342
LIG_SH2_STAP1	923	927	PF00017	0.392
LIG_SH2_STAT3	78	81	PF00017	0.535
LIG_SH2_STAT5	1060	1063	PF00017	0.448
LIG_SH2_STAT5	130	133	PF00017	0.622
LIG_SH2_STAT5	265	268	PF00017	0.545
LIG_SH2_STAT5	311	314	PF00017	0.610
LIG_SH2_STAT5	332	335	PF00017	0.694
LIG_SH2_STAT5	400	403	PF00017	0.392
LIG_SH2_STAT5	42	45	PF00017	0.594
LIG_SH2_STAT5	443	446	PF00017	0.360
LIG_SH2_STAT5	505	508	PF00017	0.412
LIG_SH2_STAT5	742	745	PF00017	0.528
LIG_SH2_STAT5	870	873	PF00017	0.556
LIG_SH2_STAT5	905	908	PF00017	0.402
LIG_SH2_STAT5	923	926	PF00017	0.267
LIG_SH2_STAT5	930	933	PF00017	0.402
LIG_SH2_STAT5	962	965	PF00017	0.376
LIG_SH2_STAT5	999	1002	PF00017	0.376
LIG_SH3_3	215	221	PF00018	0.639
LIG_SH3_3	337	343	PF00018	0.611
LIG_SH3_3	57	63	PF00018	0.688
LIG_SH3_3	726	732	PF00018	0.476
LIG_SH3_3	73	79	PF00018	0.679
LIG_SH3_3	780	786	PF00018	0.648
LIG_SH3_3	89	95	PF00018	0.499
LIG_SH3_3	967	973	PF00018	0.376
LIG_SUMO_SIM_anti_2	2	11	PF11976	0.622
LIG_SUMO_SIM_anti_2	712	718	PF11976	0.620
LIG_SUMO_SIM_anti_2	980	986	PF11976	0.430
LIG_SUMO_SIM_par_1	139	145	PF11976	0.506
LIG_SUMO_SIM_par_1	506	511	PF11976	0.430
LIG_TRAF2_1	122	125	PF00917	0.482
LIG_TYR_ITIM	903	908	PF00017	0.430
LIG_TYR_ITSM	870	877	PF00017	0.553
LIG_Vh1_VBS_1	1065	1083	PF01044	0.509
LIG_WRC_WIRS_1	129	134	PF05994	0.629
LIG_WRC_WIRS_1	54	59	PF05994	0.385
LIG_WRC_WIRS_1	892	897	PF05994	0.566
LIG_WRC_WIRS_1	932	937	PF05994	0.376
MOD_CDC14_SPxK_1	695	698	PF00782	0.595
MOD_CDK_SPxK_1	692	698	PF00069	0.594
MOD_CDK_SPxK_1	869	875	PF00069	0.480
MOD_CK1_1	105	111	PF00069	0.510
MOD_CK1_1	1068	1074	PF00069	0.474
MOD_CK1_1	200	206	PF00069	0.742
MOD_CK1_1	247	253	PF00069	0.778
MOD_CK1_1	56	62	PF00069	0.567
MOD_CK1_1	614	620	PF00069	0.708
MOD_CK1_1	621	627	PF00069	0.723
MOD_CK1_1	639	645	PF00069	0.846
MOD_CK1_1	69	75	PF00069	0.651
MOD_CK2_1	119	125	PF00069	0.745
MOD_CK2_1	658	664	PF00069	0.752
MOD_CK2_1	908	914	PF00069	0.404
MOD_GlcNHglycan	1001	1004	PF01048	0.430
MOD_GlcNHglycan	104	107	PF01048	0.582
MOD_GlcNHglycan	205	208	PF01048	0.625
MOD_GlcNHglycan	249	252	PF01048	0.782
MOD_GlcNHglycan	336	340	PF01048	0.573
MOD_GlcNHglycan	480	483	PF01048	0.501
MOD_GlcNHglycan	520	523	PF01048	0.674
MOD_GlcNHglycan	616	619	PF01048	0.731
MOD_GlcNHglycan	630	633	PF01048	0.729
MOD_GlcNHglycan	669	672	PF01048	0.687
MOD_GlcNHglycan	711	714	PF01048	0.748
MOD_GlcNHglycan	745	748	PF01048	0.553
MOD_GlcNHglycan	765	768	PF01048	0.461
MOD_GlcNHglycan	98	101	PF01048	0.564
MOD_GSK3_1	199	206	PF00069	0.536
MOD_GSK3_1	499	506	PF00069	0.501
MOD_GSK3_1	52	59	PF00069	0.584
MOD_GSK3_1	610	617	PF00069	0.680
MOD_GSK3_1	618	625	PF00069	0.691
MOD_GSK3_1	62	69	PF00069	0.616
MOD_GSK3_1	636	643	PF00069	0.561
MOD_GSK3_1	658	665	PF00069	0.722
MOD_GSK3_1	720	727	PF00069	0.614
MOD_GSK3_1	810	817	PF00069	0.615
MOD_GSK3_1	890	897	PF00069	0.491
MOD_GSK3_1	987	994	PF00069	0.460
MOD_GSK3_1	999	1006	PF00069	0.376
MOD_N-GLC_1	618	623	PF02516	0.816
MOD_N-GLC_1	829	834	PF02516	0.428
MOD_N-GLC_1	909	914	PF02516	0.430
MOD_N-GLC_2	298	300	PF02516	0.542
MOD_N-GLC_2	318	320	PF02516	0.578
MOD_N-GLC_2	655	657	PF02516	0.574
MOD_NEK2_1	1	6	PF00069	0.654
MOD_NEK2_1	1050	1055	PF00069	0.478
MOD_NEK2_1	334	339	PF00069	0.656
MOD_NEK2_1	381	386	PF00069	0.430
MOD_NEK2_1	500	505	PF00069	0.430
MOD_NEK2_1	53	58	PF00069	0.622
MOD_NEK2_1	576	581	PF00069	0.516
MOD_NEK2_1	584	589	PF00069	0.487
MOD_NEK2_1	604	609	PF00069	0.346
MOD_NEK2_1	622	627	PF00069	0.741
MOD_NEK2_1	640	645	PF00069	0.580
MOD_NEK2_1	737	742	PF00069	0.470
MOD_NEK2_1	751	756	PF00069	0.457
MOD_NEK2_1	8	13	PF00069	0.647
MOD_NEK2_2	1003	1008	PF00069	0.501
MOD_NEK2_2	260	265	PF00069	0.550
MOD_NEK2_2	438	443	PF00069	0.430
MOD_PIKK_1	1055	1061	PF00454	0.450
MOD_PIKK_1	245	251	PF00454	0.712
MOD_PIKK_1	300	306	PF00454	0.655
MOD_PIKK_1	327	333	PF00454	0.642
MOD_PIKK_1	791	797	PF00454	0.817
MOD_PIKK_1	947	953	PF00454	0.430
MOD_PK_1	64	70	PF00069	0.682
MOD_PKA_1	244	250	PF00069	0.638
MOD_PKA_1	459	465	PF00069	0.249
MOD_PKA_2	244	250	PF00069	0.635
MOD_PKA_2	280	286	PF00069	0.680
MOD_PKA_2	614	620	PF00069	0.687
MOD_PKA_2	768	774	PF00069	0.774
MOD_PKA_2	890	896	PF00069	0.325
MOD_PKA_2	921	927	PF00069	0.387
MOD_PKB_1	45	53	PF00069	0.537
MOD_PKB_1	516	524	PF00069	0.440
MOD_PKB_1	707	715	PF00069	0.683
MOD_Plk_1	381	387	PF00069	0.378
MOD_Plk_1	618	624	PF00069	0.574
MOD_Plk_1	636	642	PF00069	0.758
MOD_Plk_1	829	835	PF00069	0.475
MOD_Plk_4	1009	1015	PF00069	0.282
MOD_Plk_4	1068	1074	PF00069	0.474
MOD_Plk_4	260	266	PF00069	0.461
MOD_Plk_4	309	315	PF00069	0.651
MOD_Plk_4	348	354	PF00069	0.513
MOD_Plk_4	438	444	PF00069	0.376
MOD_Plk_4	500	506	PF00069	0.405
MOD_Plk_4	53	59	PF00069	0.628
MOD_Plk_4	622	628	PF00069	0.810
MOD_Plk_4	658	664	PF00069	0.557
MOD_Plk_4	737	743	PF00069	0.530
MOD_Plk_4	8	14	PF00069	0.715
MOD_Plk_4	891	897	PF00069	0.502
MOD_ProDKin_1	105	111	PF00069	0.565
MOD_ProDKin_1	184	190	PF00069	0.423
MOD_ProDKin_1	254	260	PF00069	0.543
MOD_ProDKin_1	56	62	PF00069	0.663
MOD_ProDKin_1	692	698	PF00069	0.761
MOD_ProDKin_1	775	781	PF00069	0.733
MOD_ProDKin_1	782	788	PF00069	0.638
MOD_ProDKin_1	869	875	PF00069	0.480
MOD_ProDKin_1	91	97	PF00069	0.512
MOD_SUMO_rev_2	316	325	PF00179	0.569
MOD_SUMO_rev_2	990	998	PF00179	0.376
TRG_DiLeu_BaEn_1	382	387	PF01217	0.430
TRG_DiLeu_BaEn_2	484	490	PF01217	0.430
TRG_DiLeu_BaEn_4	382	388	PF01217	0.430
TRG_DiLeu_BaLyEn_6	453	458	PF01217	0.430
TRG_DiLeu_BaLyEn_6	536	541	PF01217	0.576
TRG_DiLeu_BaLyEn_6	951	956	PF01217	0.376
TRG_DiLeu_LyEn_5	382	387	PF01217	0.430
TRG_ENDOCYTIC_2	1004	1007	PF00928	0.402
TRG_ENDOCYTIC_2	311	314	PF00928	0.610
TRG_ENDOCYTIC_2	390	393	PF00928	0.501
TRG_ENDOCYTIC_2	505	508	PF00928	0.404
TRG_ENDOCYTIC_2	874	877	PF00928	0.426
TRG_ENDOCYTIC_2	905	908	PF00928	0.430
TRG_ENDOCYTIC_2	930	933	PF00928	0.376
TRG_ER_diArg_1	243	245	PF00400	0.588
TRG_ER_diArg_1	353	355	PF00400	0.651
TRG_ER_diArg_1	44	47	PF00400	0.566
TRG_ER_diArg_1	516	518	PF00400	0.441
TRG_ER_diArg_1	541	543	PF00400	0.571
TRG_NES_CRM1_1	499	511	PF08389	0.430
TRG_NES_CRM1_1	887	901	PF08389	0.579
TRG_Pf-PMV_PEXEL_1	456	461	PF00026	0.405
TRG_Pf-PMV_PEXEL_1	542	546	PF00026	0.522
TRG_Pf-PMV_PEXEL_1	954	959	PF00026	0.376

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P435	Leptomonas seymouri	59%	96%
A0A3Q8IGA3	Leishmania donovani	86%	100%
A4I109	Leishmania infantum	86%	100%
C9ZWA0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	100%
E9AX47	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%
Q4QAC9	Leishmania major	85%	100%